RU95101846A - Polysubstituted derivatives of 3-acylamino-5-phenyl-1,4-benzodiazepine-2-one, method of their synthesis and pharmaceutical composition containing thereof - Google Patents

Polysubstituted derivatives of 3-acylamino-5-phenyl-1,4-benzodiazepine-2-one, method of their synthesis and pharmaceutical composition containing thereof

Info

Publication number
RU95101846A
RU95101846A RU95101846/04A RU95101846A RU95101846A RU 95101846 A RU95101846 A RU 95101846A RU 95101846/04 A RU95101846/04 A RU 95101846/04A RU 95101846 A RU95101846 A RU 95101846A RU 95101846 A RU95101846 A RU 95101846A
Authority
RU
Russia
Prior art keywords
synthesis
benzodiazepine
acylamino
phenyl
pharmaceutical composition
Prior art date
Application number
RU95101846/04A
Other languages
Russian (ru)
Other versions
RU2142948C1 (en
Inventor
Вадорк Ален
Fr]
Депейру Пьер
Гюллий Даниель
де Куанте Поль
Фреель Даниель
Маффран Жан-Пьер
Original Assignee
Санофи (FR)
Санофи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9408665A external-priority patent/FR2716195B1/en
Application filed by Санофи (FR), Санофи filed Critical Санофи (FR)
Publication of RU95101846A publication Critical patent/RU95101846A/en
Application granted granted Critical
Publication of RU2142948C1 publication Critical patent/RU2142948C1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

FIELD: organic chemistry. SUBSTANCE: product: compounds of the formula (I) given in description that show agonistic activity with respect to "ССК"-receptors, method of their synthesis and pharmcompositions based on thereof. EFFECT: improved method of synthesis.

Claims (1)

Изобретение относится к соединениям формулы I (см. описание), которые проявляют агонистическую активность в отношении рецепторов ССК, к способу их получения и фармкомпозициям на их основе.The invention relates to compounds of formula I (see description) that exhibit agonistic activity against CCK receptors, to a method for their preparation and pharmaceutical compositions based on them.
RU95101846A 1994-02-14 1995-02-13 Substituted 3-acylamino-5-phenyl-1,4-benzodiazepin 2-one derivatives, method of preparation thereof, and intermediate product RU2142948C1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9401642A FR2716194B1 (en) 1994-02-14 1994-02-14 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them
FR9401642 1994-02-14
FR9408665A FR2716195B1 (en) 1994-02-14 1994-07-12 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them
FR9408665 1994-07-12

Publications (2)

Publication Number Publication Date
RU95101846A true RU95101846A (en) 1996-12-27
RU2142948C1 RU2142948C1 (en) 1999-12-20

Family

ID=9460046

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95101846A RU2142948C1 (en) 1994-02-14 1995-02-13 Substituted 3-acylamino-5-phenyl-1,4-benzodiazepin 2-one derivatives, method of preparation thereof, and intermediate product

Country Status (3)

Country Link
FR (1) FR2716194B1 (en)
RU (1) RU2142948C1 (en)
ZA (1) ZA951136B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4204657B2 (en) * 1997-12-05 2009-01-07 有限会社ケムフィズ Diabetes prevention and treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
FR2641280B1 (en) * 1988-12-29 1994-01-21 Roussel Uclaf NOVEL 2,4-DIOXO 2,3,4,5-TETRAHYDRO 1H-1,5-BENZODIAZEPINE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS

Also Published As

Publication number Publication date
FR2716194B1 (en) 1996-05-31
FR2716194A1 (en) 1995-08-18
ZA951136B (en) 1996-08-13
RU2142948C1 (en) 1999-12-20

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