FR2716194B1 - Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents

Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
FR2716194B1
FR2716194B1 FR9401642A FR9401642A FR2716194B1 FR 2716194 B1 FR2716194 B1 FR 2716194B1 FR 9401642 A FR9401642 A FR 9401642A FR 9401642 A FR9401642 A FR 9401642A FR 2716194 B1 FR2716194 B1 FR 2716194B1
Authority
FR
France
Prior art keywords
benzodiazepin
polysubstituted
acylamino
phenyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9401642A
Other languages
French (fr)
Other versions
FR2716194A1 (en
Inventor
Alain Badorc
Pierre Despeyroux
Daniele Gully
Cointet Paul De
Daniel Frehel
Jean-Pierre Maffrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elf Sanofi SA
Original Assignee
Elf Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elf Sanofi SA filed Critical Elf Sanofi SA
Priority to FR9401642A priority Critical patent/FR2716194B1/en
Priority to FR9408665A priority patent/FR2716195B1/en
Priority to IL11258995A priority patent/IL112589A/en
Priority to AU11668/95A priority patent/AU692202B2/en
Priority to NZ270478A priority patent/NZ270478A/en
Priority to NO950537A priority patent/NO307784B1/en
Priority to RU95101846A priority patent/RU2142948C1/en
Priority to ZA951136A priority patent/ZA951136B/en
Priority to FI950625A priority patent/FI950625A/en
Priority to HU9500434A priority patent/HUT70050A/en
Priority to KR1019950002560A priority patent/KR950032145A/en
Priority to CN95101504A priority patent/CN1053438C/en
Priority to EP95400293A priority patent/EP0667344A1/en
Priority to JP7023848A priority patent/JPH07300467A/en
Priority to CA002142411A priority patent/CA2142411A1/en
Priority to PL95307255A priority patent/PL179904B1/en
Priority to US08/390,770 priority patent/US5719143A/en
Priority to TW084101431A priority patent/TW427982B/en
Publication of FR2716194A1 publication Critical patent/FR2716194A1/en
Application granted granted Critical
Publication of FR2716194B1 publication Critical patent/FR2716194B1/en
Priority to US08/975,003 priority patent/US5798353A/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9401642A 1994-02-14 1994-02-14 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them Expired - Fee Related FR2716194B1 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
FR9401642A FR2716194B1 (en) 1994-02-14 1994-02-14 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them
FR9408665A FR2716195B1 (en) 1994-02-14 1994-07-12 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them
IL11258995A IL112589A (en) 1994-02-14 1995-02-09 Polysubstituted-3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives process and novel intermediates for their preparation and pharmaceutical compositions containing them
NZ270478A NZ270478A (en) 1994-02-14 1995-02-10 Benzodiazepine derivatives, pharmaceutical compositions thereof and intermediates
AU11668/95A AU692202B2 (en) 1994-02-14 1995-02-10 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-onederivatives, process for their preparation and the pharmaceutical compositions containing them
CA002142411A CA2142411A1 (en) 1994-02-14 1995-02-13 Polysubstituted 3-acylamino-5-phenyl-1,4- benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them
ZA951136A ZA951136B (en) 1994-02-14 1995-02-13 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives process for their preparation and the pharmaceutical compositions containing them
FI950625A FI950625A (en) 1994-02-14 1995-02-13 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them
HU9500434A HUT70050A (en) 1994-02-14 1995-02-13 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for producing them and pharmaceutical compositions containing them
KR1019950002560A KR950032145A (en) 1994-02-14 1995-02-13 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, methods for their preparation and pharmaceutical compositions containing them
NO950537A NO307784B1 (en) 1994-02-14 1995-02-13 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, pharmaceutical compositions containing them and intermediates for their preparation
EP95400293A EP0667344A1 (en) 1994-02-14 1995-02-13 3-acylamino-5-(polysubstituted phenyl)-1,4-benzodiazepin-2-ones useful as CCK-receptor agonists
JP7023848A JPH07300467A (en) 1994-02-14 1995-02-13 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-onederivative,its production and medicinal composition containing same
RU95101846A RU2142948C1 (en) 1994-02-14 1995-02-13 Substituted 3-acylamino-5-phenyl-1,4-benzodiazepin 2-one derivatives, method of preparation thereof, and intermediate product
CN95101504A CN1053438C (en) 1994-02-14 1995-02-13 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them
PL95307255A PL179904B1 (en) 1994-02-14 1995-02-14 Polysubstituted derivatives of 3-acylamine 5-phenyl-1,4-benzoazepin-2-one, method of obtaining them and pharmaceutical preparations containing such derivatives
US08/390,770 US5719143A (en) 1994-02-14 1995-02-14 Polysubstituted 3-acylamino-5-phenyl-1, 4-benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them
TW084101431A TW427982B (en) 1994-02-14 1995-02-16 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them
US08/975,003 US5798353A (en) 1994-02-14 1997-11-20 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9401642A FR2716194B1 (en) 1994-02-14 1994-02-14 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
FR2716194A1 FR2716194A1 (en) 1995-08-18
FR2716194B1 true FR2716194B1 (en) 1996-05-31

Family

ID=9460046

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9401642A Expired - Fee Related FR2716194B1 (en) 1994-02-14 1994-02-14 Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and pharmaceutical compositions containing them

Country Status (3)

Country Link
FR (1) FR2716194B1 (en)
RU (1) RU2142948C1 (en)
ZA (1) ZA951136B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4204657B2 (en) * 1997-12-05 2009-01-07 有限会社ケムフィズ Diabetes prevention and treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
FR2641280B1 (en) * 1988-12-29 1994-01-21 Roussel Uclaf NOVEL 2,4-DIOXO 2,3,4,5-TETRAHYDRO 1H-1,5-BENZODIAZEPINE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS

Also Published As

Publication number Publication date
RU95101846A (en) 1996-12-27
FR2716194A1 (en) 1995-08-18
ZA951136B (en) 1996-08-13
RU2142948C1 (en) 1999-12-20

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TP Transmission of property
ST Notification of lapse