RU94026248A - METHODS FOR PRODUCING CARBOHYDRATE fucosylated by enzymic fucosylation NUCLEOTIDE sugar with GDP-fucose REGENERATION IN SITU, REACTION SYSTEM IN VITRO, METHOD FOR PRODUCING glycosyl 1- or 2-phosphite-protected FOSFITILNY monosaccharides GALOIDGIDRATIROVANIYA METHOD, GLIKOZILGALOIDGIDRINY - Google Patents

METHODS FOR PRODUCING CARBOHYDRATE fucosylated by enzymic fucosylation NUCLEOTIDE sugar with GDP-fucose REGENERATION IN SITU, REACTION SYSTEM IN VITRO, METHOD FOR PRODUCING glycosyl 1- or 2-phosphite-protected FOSFITILNY monosaccharides GALOIDGIDRATIROVANIYA METHOD, GLIKOZILGALOIDGIDRINY

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Publication number
RU94026248A
RU94026248A RU94026248/13A RU94026248A RU94026248A RU 94026248 A RU94026248 A RU 94026248A RU 94026248/13 A RU94026248/13 A RU 94026248/13A RU 94026248 A RU94026248 A RU 94026248A RU 94026248 A RU94026248 A RU 94026248A
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RU
Russia
Prior art keywords
producing
methods
fucosylation
fucosylated
glikozilgaloidgidriny
Prior art date
Application number
RU94026248/13A
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Russian (ru)
Other versions
RU2125092C1 (en
Inventor
Вонг Ти-Хью
Итикава Еситака
Сен Гво-Енн
Лиу Кун-Тин
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Дзе Скриппс Рисерч Инститьют
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Application filed by Дзе Скриппс Рисерч Инститьют filed Critical Дзе Скриппс Рисерч Инститьют
Priority claimed from PCT/US1992/008789 external-priority patent/WO1993008205A1/en
Publication of RU94026248A publication Critical patent/RU94026248A/en
Application granted granted Critical
Publication of RU2125092C1 publication Critical patent/RU2125092C1/en

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Claims (1)

Настоящее изобретение относится к усовершенствованным способам ферментативного получения углеводов, особенно фукозилированных углеводов. Предложены также усовершенствованные способы получения гликозил-1- или 2-фосфатов с использованием как химических, так и ферментативных средств. Далее фосфорилированные гликозиды используют для получения нуклеотидов сахаров, которые, в свою очередь, используют как донорные сахара для гликозилирования акцепторных углеводов, которые наиболее предпочтительны при использовании раскрытых здесь способов фукозилирования.The present invention relates to improved methods for the enzymatic production of carbohydrates, especially fucosylated carbohydrates. Improved methods for the production of glycosyl-1- or 2-phosphates using both chemical and enzymatic agents are also proposed. Further, phosphorylated glycosides are used to obtain sugar nucleotides, which, in turn, are used as donor sugars for glycosylation of acceptor carbohydrates, which are most preferable when using the methods of fucosylation disclosed here.
RU94026248A 1991-10-15 1992-10-15 Method of synthesis of fucosylated carbohydrate, method of synthesis of fucosylated sialylated carbohydrate molecule, reaction system in vitro RU2125092C1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US77766291A 1991-10-15 1991-10-15
US777662 1991-10-15
US777,662 1991-10-15
US901260 1992-06-19
US910612 1992-07-08
PCT/US1992/008789 WO1993008205A1 (en) 1991-10-15 1992-10-15 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of gdp-fucose
US961076 2001-09-21

Publications (2)

Publication Number Publication Date
RU94026248A true RU94026248A (en) 1995-11-27
RU2125092C1 RU2125092C1 (en) 1999-01-20

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RU (1) RU2125092C1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2456292T3 (en) * 2006-03-09 2014-04-21 Centre National De La Recherche Scientifique (Cnrs) Sialylated oligosaccharide production process
CN102257128A (en) * 2008-12-19 2011-11-23 詹内怀恩生物技术股份有限公司 Synthesis of fucosylated compounds
EP2944690B1 (en) * 2010-10-11 2017-12-20 Jennewein Biotechnologie GmbH Novel fucosyltransferases and their applications
EP2479263B1 (en) * 2011-01-20 2013-11-27 Jennewein Biotechnologie GmbH Novel Fucosyltransferases and their applications
AU2012225900B2 (en) * 2011-03-04 2015-09-17 Glytech, Inc. Method for producing sialic-acid-containing sugar chain
EP3050973A1 (en) * 2015-01-30 2016-08-03 Jennewein Biotechnologie GmbH Fermentation process for producing monosaccharides in free form from nucleotide-activated sugars

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