RU94016876A - IMIDAZO DERIVATIVES (5,1-С) (1,4) BENZOXAZIN-1-SHE, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION AND INTERMEDIATE CONNECTIONS - Google Patents
IMIDAZO DERIVATIVES (5,1-С) (1,4) BENZOXAZIN-1-SHE, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION AND INTERMEDIATE CONNECTIONSInfo
- Publication number
- RU94016876A RU94016876A RU94016876/04A RU94016876A RU94016876A RU 94016876 A RU94016876 A RU 94016876A RU 94016876/04 A RU94016876/04 A RU 94016876/04A RU 94016876 A RU94016876 A RU 94016876A RU 94016876 A RU94016876 A RU 94016876A
- Authority
- RU
- Russia
- Prior art keywords
- benzoxazin
- production
- pharmaceutical composition
- intermediate connections
- imidazo
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000012450 pharmaceutical intermediate Substances 0.000 title 1
- PVTXJGJDOHYFOX-UHFFFAOYSA-N 2H-1,4-benzoxazine Chemical compound C1=CC=C2N=CCOC2=C1 PVTXJGJDOHYFOX-UHFFFAOYSA-N 0.000 claims 1
- 229940035676 ANALGESICS Drugs 0.000 claims 1
- 206010012335 Dependence Diseases 0.000 claims 1
- 208000008085 Migraine Disorders Diseases 0.000 claims 1
- 206010047700 Vomiting Diseases 0.000 claims 1
- 239000012190 activator Substances 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 230000000202 analgesic Effects 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 125000001589 carboacyl group Chemical group 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000003930 cognitive ability Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 201000009457 movement disease Diseases 0.000 claims 1
- 239000004081 narcotic agent Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Claims (1)
в которой среди прочих символов R3 представляет
где n представляет целое число 1 или 2, и R8 представляет водород, /1 - 6/C алкил, незамещенный или замещенный фенилом, /2 - 4/C алкенил, /2 - 4/C алкинил, формил или /2 - 6/C алканоил, и их фармацевтически приемлемые соли, которые полезны при лечении нарушений ЦНС, расстройств двигательной активности кишечника, рвоты и мигрени, в качестве активатора познавательной способности, агентов против привыкания к чрезмерному употреблению лекарственных средств или к наркотическим агентам, и в качестве анальгетиков.The invention provides derivatives of 2, 3, 3a, 4-tetrahydro-2-azabicyclo-alkyl-IH-imidazo [5,1 - c] [1, 4] benzoxazine I-she of the general formula
in which, among other characters, R 3 represents
where n represents an integer of 1 or 2, and R 8 represents hydrogen, / 1 - 6 / C alkyl, unsubstituted or substituted by phenyl, / 2-4 / C alkenyl, / 2-4 / C alkynyl, formyl or / 2-6 / C alkanoyl, and their pharmaceutically acceptable salts, which are useful in treating CNS disorders, bowel movement disorders, vomiting and migraines, as an activator of cognitive ability, agents against addiction to excessive drug use or narcotic agents, and as analgesics.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB92124866 | 1992-06-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU94016876A true RU94016876A (en) | 1995-09-27 |
Family
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