RU94000063A - BIPHENYLIC DERIVATIVES, METHOD OF THEIR PRODUCTION, INTERMEDIATE PRODUCTS FOR THEIR SYNTHESIS - Google Patents
BIPHENYLIC DERIVATIVES, METHOD OF THEIR PRODUCTION, INTERMEDIATE PRODUCTS FOR THEIR SYNTHESISInfo
- Publication number
- RU94000063A RU94000063A RU94000063/04A RU94000063A RU94000063A RU 94000063 A RU94000063 A RU 94000063A RU 94000063/04 A RU94000063/04 A RU 94000063/04A RU 94000063 A RU94000063 A RU 94000063A RU 94000063 A RU94000063 A RU 94000063A
- Authority
- RU
- Russia
- Prior art keywords
- synthesis
- derivatives
- biphenylic
- production
- intermediate products
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title claims 2
- 238000003786 synthesis reaction Methods 0.000 title claims 2
- 230000002194 synthesizing Effects 0.000 title claims 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 239000000543 intermediate Substances 0.000 claims 1
- -1 phenyl halide compound Chemical class 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
Claims (1)
где X обозначает в случае необходимости защищенную формильную группу, R обозначает группу, инертную в реакционных условиях, например -CN, а также к способу их получения, заключающемуся в том, что соединение общей формулы (II):
причем X имеет вышеуказанное значение, вводят во взаимодействие с замещенным фенилгалоидным соединением формулы (III):
где Гал обозначает, например, бром. Соединения являются ценными промежуточными продуктами для синтеза лекарственных средств.The invention relates to biphenyl derivatives of General formula (I):
where X denotes, if necessary, a protected formyl group, R denotes a group that is inert under the reaction conditions, for example —CN, as well as to the method for their preparation, namely, that the compound of general formula (II)
moreover, X has the above value, enter into interaction with the substituted phenyl halide compound of formula (III):
where Gal means, for example, bromine. The compounds are valuable intermediates for the synthesis of drugs.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP4300137.8 | 1993-01-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU94000063A true RU94000063A (en) | 1995-09-10 |
Family
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