RU93058237A - PRODUCTION 4-ARIL-B- (HETEROARYLUREIDO) QUINOLINE, PRODUCTION METHODS, PHARMACEUTICAL COMPOSITION - Google Patents

PRODUCTION 4-ARIL-B- (HETEROARYLUREIDO) QUINOLINE, PRODUCTION METHODS, PHARMACEUTICAL COMPOSITION

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Publication number
RU93058237A
RU93058237A RU93058237/04A RU93058237A RU93058237A RU 93058237 A RU93058237 A RU 93058237A RU 93058237/04 A RU93058237/04 A RU 93058237/04A RU 93058237 A RU93058237 A RU 93058237A RU 93058237 A RU93058237 A RU 93058237A
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RU
Russia
Prior art keywords
production
heteroarylureido
aril
quinoline
pharmaceutical composition
Prior art date
Application number
RU93058237/04A
Other languages
Russian (ru)
Inventor
С.Хоманака Эрнст
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of RU93058237A publication Critical patent/RU93058237A/en

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Claims (1)

Предложены соединения общей формулы I
Figure 00000001

их фармацевтически приемлемые соли, где R1, R2, R3, R4, m, X и Q определены ниже, и новые промежуточные соединения, использованные для синтеза указанных соединений. Соединения общей формулы I являются ингибиторам ацилкоэнзима А: холестеринацилтрансферазы (АСАТ) и используются в качестве гиполипидемических и антиатеросклерозных агентов.Compounds of general formula I are provided
Figure 00000001

their pharmaceutically acceptable salts, where R 1 , R 2 , R 3 , R 4 , m, X and Q are defined below, and new intermediates used for the synthesis of these compounds. The compounds of general formula I are inhibitors of acylcoenzyme A: cholesterol acyltransferase (ACAT) and are used as lipid-lowering and anti-atherosclerosis agents.
RU93058237/04A 1991-04-26 1992-03-16 PRODUCTION 4-ARIL-B- (HETEROARYLUREIDO) QUINOLINE, PRODUCTION METHODS, PHARMACEUTICAL COMPOSITION RU93058237A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US692,323 1991-04-26

Publications (1)

Publication Number Publication Date
RU93058237A true RU93058237A (en) 1997-01-20

Family

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