RU93053905A - OXYPURINE NUCLEOSIDES AND RELATED COMPOUNDS THEREOF, AND ALSO THEIR Acyl DERIVATIVES TO IMPROVE HEMOPOESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT AND / OR PREVENTION - Google Patents

OXYPURINE NUCLEOSIDES AND RELATED COMPOUNDS THEREOF, AND ALSO THEIR Acyl DERIVATIVES TO IMPROVE HEMOPOESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT AND / OR PREVENTION

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Publication number
RU93053905A
RU93053905A RU93053905/14A RU93053905A RU93053905A RU 93053905 A RU93053905 A RU 93053905A RU 93053905/14 A RU93053905/14 A RU 93053905/14A RU 93053905 A RU93053905 A RU 93053905A RU 93053905 A RU93053905 A RU 93053905A
Authority
RU
Russia
Prior art keywords
hemopoesis
prevention
treatment
improve
pharmaceutical composition
Prior art date
Application number
RU93053905/14A
Other languages
Russian (ru)
Other versions
RU2158269C2 (en
Inventor
Уоррен Фон БОРСТЕЛ Рейд
Кевин БЭМАТ Майкл
Марк Хилтбрэнд Бредли
Чарльз БАТЛЕР Джеймс
Original Assignee
Про-Ньюрон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Про-Ньюрон, Инк. filed Critical Про-Ньюрон, Инк.
Publication of RU93053905A publication Critical patent/RU93053905A/en
Application granted granted Critical
Publication of RU2158269C2 publication Critical patent/RU2158269C2/en

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Claims (1)

Изобретение относится к определенным оксипуриновым нуклеозидам, родственным им соединениям и ацильным производным таких соединений, а также к композициям, которые содержат по меньшей мере одно из таких соединений. Изобретение относится также к способам лечения или предотвращения гемопоэтических (кровотворных) нарушений и изменения гемопоэза путем назначения животному соединения или композиции по настоящему изобретению.The invention relates to certain oxypurine nucleosides, related compounds and an acyl derivative of such compounds, as well as to compositions that contain at least one of such compounds. The invention also relates to methods for treating or preventing hematopoietic (hematopoietic) disorders and changes in hematopoiesis by administering to an animal a compound or composition of the present invention.
RU93053905/14A 1991-02-08 1992-02-05 Acyl derivatives of guanosine, inosine, xanthosine, deoxy-inosine, deoxyguanosine, inosine-2',3'-(acyclic)-dialcohol or their pharmaceutically acceptable salts, hemopoiesis-stimulating pharmaceutical composition, method of treatment of cytopenia RU2158269C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65388291A 1991-02-08 1991-02-08
US653,882 1991-02-08

Publications (2)

Publication Number Publication Date
RU93053905A true RU93053905A (en) 1997-04-10
RU2158269C2 RU2158269C2 (en) 2000-10-27

Family

ID=24622651

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93053905/14A RU2158269C2 (en) 1991-02-08 1992-02-05 Acyl derivatives of guanosine, inosine, xanthosine, deoxy-inosine, deoxyguanosine, inosine-2',3'-(acyclic)-dialcohol or their pharmaceutically acceptable salts, hemopoiesis-stimulating pharmaceutical composition, method of treatment of cytopenia

Country Status (12)

Country Link
EP (1) EP0570519B1 (en)
JP (6) JP3393645B2 (en)
KR (2) KR100263943B1 (en)
AT (1) ATE179615T1 (en)
AU (1) AU663309C (en)
CA (2) CA2100655C (en)
DE (1) DE69229108T2 (en)
HK (1) HK1003425A1 (en)
IL (1) IL100874A (en)
RU (1) RU2158269C2 (en)
WO (1) WO1992013561A1 (en)
ZA (1) ZA92914B (en)

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SE9800452D0 (en) * 1998-02-13 1998-02-13 Medivir Ab antivirals
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
US7307166B1 (en) 1987-10-28 2007-12-11 Wellstat Therapeutics Corporation Oxpurine nucleosides and their congeners, and acyl, derivatives thereof, for improvement of hematopoiesis
CA2504078C (en) * 1991-07-05 2007-08-28 Wellstat Therapeutics Corporation Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides
US5641758A (en) * 1993-11-10 1997-06-24 Kluge; Michael Cytarabine derivatives, the preparation and use thereof
US5762922A (en) * 1994-01-31 1998-06-09 Ludwig Institute For Cancer Research Antioxidants and intracellular gluthathione raising agents for therapeutic treatments
WO1996004923A1 (en) * 1994-08-12 1996-02-22 Pro-Neuron, Inc. Methods for treating sepsis or inflammatory diseases with oxypurine nucleosides
ES2158689T3 (en) * 1997-08-15 2001-09-01 Medivir Ab ANALOGS OF NUCLEOSIDS, SUCH AS ANTIVIRALS, INCLUDING INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTASE AND THE DNA-POLYMERASE OF HEPATITIS B VIRUS (HBV).
WO1999051613A1 (en) * 1998-04-03 1999-10-14 Medivir Ab Prodrugs of phosphorous-containing pharmaceuticals
EP1567112B1 (en) * 2002-11-22 2008-10-15 Smithkline Beecham Corporation THIAZOLIDIN-4-ONES FOR INHIBITING hYAK3 PROTEINS
JP3929949B2 (en) 2003-08-08 2007-06-13 独立行政法人科学技術振興機構 Nucleoside releasing functional unit by oxidation and method for producing oligonucleotide containing the same
AU2016222458B2 (en) * 2007-08-16 2018-11-08 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions containing Nucleosides and Manganese and their Uses
WO2009045655A2 (en) * 2007-08-16 2009-04-09 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Compositions containing purine nucleosides and manganese and their uses
JP5916147B2 (en) 2010-04-29 2016-05-11 ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド Compositions containing purine and pyrimidine nucleosides, peptides and manganese and their use
BR112015025206A2 (en) 2013-04-08 2017-07-18 Univ Texas telomerase-mediated telomer altering compounds
JP2021514985A (en) * 2018-03-02 2021-06-17 ジャニュアリー セラピューティクス，インク． Nanoparticle composition

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US4002963A (en) * 1975-05-29 1977-01-11 North Electric Company Converter circuit and method having fast responding current balance and limiting
IT1202370B (en) * 1976-07-12 1989-02-09 Hoffmann La Roche INJECTABLE SOLUTIONS IN WHICH THE EMOLITHIC LIFE OF NATURAL MICELLES TRAINING AGENTS IS AVOIDED BY THE ADDITION OF LIPOIDS AND RELATED PRODUCTS
US4849411A (en) * 1982-11-09 1989-07-18 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
GB2177914B (en) * 1985-06-04 1989-10-25 Chugai Pharmaceutical Co Ltd A pharmaceutical composition containing human erythropoietin and a surface active agent for nasal administration for the treatment of anemia
ATE142221T1 (en) * 1987-10-28 1996-09-15 Pro Neuron Inc ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF
WO1989003837A1 (en) * 1987-10-28 1989-05-05 Pro-Neuron, Inc. Acylated uridine and cytidine and uses thereof
ZA892928B (en) * 1988-04-25 1991-01-30 Pro Neuron Inc Pharmaceutical compositions containing deoxyribonucleosides for wound healing
ATE111157T1 (en) * 1988-04-29 1994-09-15 Genetics Inst STORAGE-STABLE COMPOSITIONS OF HOMOGENEOUS DIMER M-CSF.

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