RU93052889A - ECHO-CONTRAST MATTER AND METHOD OF ITS PRODUCTION - Google Patents

ECHO-CONTRAST MATTER AND METHOD OF ITS PRODUCTION

Info

Publication number
RU93052889A
RU93052889A RU93052889/14A RU93052889A RU93052889A RU 93052889 A RU93052889 A RU 93052889A RU 93052889/14 A RU93052889/14 A RU 93052889/14A RU 93052889 A RU93052889 A RU 93052889A RU 93052889 A RU93052889 A RU 93052889A
Authority
RU
Russia
Prior art keywords
echo
production
contrast
matter
contrast matter
Prior art date
Application number
RU93052889/14A
Other languages
Russian (ru)
Other versions
RU2091079C1 (en
Inventor
Беллер Клаус-Дитер
Линдер Рудольф
Original Assignee
Бик Гульден Ломберг Хемише Фабрик ГмбХ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4100470A external-priority patent/DE4100470A1/en
Application filed by Бик Гульден Ломберг Хемише Фабрик ГмбХ filed Critical Бик Гульден Ломберг Хемише Фабрик ГмбХ
Publication of RU93052889A publication Critical patent/RU93052889A/en
Application granted granted Critical
Publication of RU2091079C1 publication Critical patent/RU2091079C1/en

Links

Claims (1)

Предложен водный раствор для поглощения и стабилизации газовых микропузырьков для применения в качестве эхоконтрастных веществ, содержащий полиоксиэтиленполиоксипропиленовые полимеры и отрицательно заряженные фосфолипиды, который пригоден для изображения левого предсердия.An aqueous solution is proposed for absorption and stabilization of gas microbubbles for use as echo contrast agents, containing polyoxyethylene polyoxypropylene polymers and negatively charged phospholipids, which is suitable for imaging the left atrium.
RU9293052889A 1991-01-09 1992-01-04 Aqueous solution for preparing the contrasting medium used in ultrasonic diagnosis and a method of its preparing RU2091079C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP4100470.1 1991-01-09
DE4100470A DE4100470A1 (en) 1991-01-09 1991-01-09 Echo contrast agent
PCT/EP1992/000012 WO1992011873A1 (en) 1991-01-09 1992-01-04 Echo contrast agent

Publications (2)

Publication Number Publication Date
RU93052889A true RU93052889A (en) 1996-10-10
RU2091079C1 RU2091079C1 (en) 1997-09-27

Family

ID=6422745

Family Applications (1)

Application Number Title Priority Date Filing Date
RU9293052889A RU2091079C1 (en) 1991-01-09 1992-01-04 Aqueous solution for preparing the contrasting medium used in ultrasonic diagnosis and a method of its preparing

Country Status (25)

Country Link
US (1) US5599523A (en)
EP (2) EP0566601B2 (en)
JP (1) JP3290655B2 (en)
KR (1) KR100203221B1 (en)
AT (1) ATE126708T1 (en)
AU (1) AU652803B2 (en)
BG (1) BG61667B2 (en)
CA (1) CA2098915C (en)
CZ (1) CZ280939B6 (en)
DE (3) DE4100470A1 (en)
DK (1) DK0566601T4 (en)
ES (1) ES2079176T5 (en)
FI (1) FI119913B (en)
GR (1) GR3017925T3 (en)
HK (1) HK1006147A1 (en)
HU (1) HU220763B1 (en)
IE (1) IE70131B1 (en)
IL (1) IL100607A (en)
NZ (1) NZ241246A (en)
PL (1) PL167253B1 (en)
RU (1) RU2091079C1 (en)
SK (1) SK278776B6 (en)
UA (1) UA27121C2 (en)
WO (1) WO1992011873A1 (en)
ZA (1) ZA92118B (en)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
IN172208B (en) 1990-04-02 1993-05-01 Sint Sa
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US20010024638A1 (en) * 1992-11-02 2001-09-27 Michel Schneider Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20040208826A1 (en) * 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9106686D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
GB9107628D0 (en) * 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
US5993805A (en) * 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
MX9205298A (en) * 1991-09-17 1993-05-01 Steven Carl Quay GASEOUS ULTRASOUND CONTRASTING MEDIA AND METHOD FOR SELECTING GASES TO BE USED AS ULTRASOUND CONTRASTING MEDIA
US6875420B1 (en) 1991-09-17 2005-04-05 Amersham Health As Method of ultrasound imaging
US6723303B1 (en) 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
JP3231768B2 (en) * 1991-09-17 2001-11-26 ソーナス ファーマシューティカルス，インコーポレイテッド Gaseous ultrasonic contrast agent and method for selecting gas to be used as ultrasonic contrast agent
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
GB9221329D0 (en) * 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Phase shift colloids as ultrasound contrast agents
PL176116B1 (en) * 1993-01-25 1999-04-30 Sonus Pharma Inc Colloidal suspensions able to undergo phase transitions for use as usg contrast media
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
US5716597A (en) * 1993-06-04 1998-02-10 Molecular Biosystems, Inc. Emulsions as contrast agents and method of use
US5798091A (en) 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
WO1995003835A1 (en) 1993-07-30 1995-02-09 Alliance Pharmaceutical Corp. Stabilized microbubble compositions for ultrasound
DE4328642A1 (en) * 1993-08-26 1995-03-02 Byk Gulden Lomberg Chem Fab Ultrasound contrast media
GB9318288D0 (en) * 1993-09-03 1993-10-20 Nycomed Imaging As Improvements in or relating to contrast agents
RU2138293C1 (en) * 1993-12-15 1999-09-27 Бракко Рисерч С.А. Contrast substances for ultrasonic echography, contrast means containing these substances, and method of preparation thereof
GB9417941D0 (en) * 1994-09-06 1994-10-26 Nycomed Imaging As Improvements in or relating to contrast agents
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
GB9423419D0 (en) * 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
WO2004073750A1 (en) * 1995-06-07 2004-09-02 Harald Dugstad Improvements in or relating to contrast agents
KR100500334B1 (en) 1996-02-19 2005-09-09 아머샴 헬스 에이에스 Improvements in or Relating to Contrast Agents
PT904113E (en) * 1996-03-05 2004-09-30 Acusphere Inc FLUORATED GASES MICROENCAPSULATED FOR USE AS IMAGE ACQUISITIVE AGENTS
DE19626530A1 (en) * 1996-07-02 1998-01-15 Byk Gulden Lomberg Chem Fab Aqueous magnetic resonance contrast agent compositions
CZ28999A3 (en) * 1996-08-02 1999-07-14 Nycomed Imaging As Use of contrast preparation
US6017310A (en) * 1996-09-07 2000-01-25 Andaris Limited Use of hollow microcapsules
US6068600A (en) * 1996-12-06 2000-05-30 Quadrant Healthcare (Uk) Limited Use of hollow microcapsules
GB9701237D0 (en) * 1997-01-22 1997-03-12 Nycomed Imaging As Improvements in or relating to contrast agents
US6054118A (en) * 1997-01-22 2000-04-25 Nycomed Imaging As Contrast agents comprising two types of gas-containing microparticles
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19805012A1 (en) * 1998-02-07 1999-08-12 Thomas Gieselmann Contrast agent for use as a diagnostic agent in imaging processes and its production
GB9912356D0 (en) 1999-05-26 1999-07-28 Btg Int Ltd Generation of microfoam
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
JP2007511590A (en) 2003-11-17 2007-05-10 ビーティージー・インターナショナル・リミテッド Therapeutic form
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
GB0509824D0 (en) 2005-05-13 2005-06-22 Btg Int Ltd Therapeutic foam
US20070140973A1 (en) * 2005-12-15 2007-06-21 Bristol-Myers Squibb Pharma Company Contrast agents for myocardium perfusion imaging

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3141641A1 (en) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen ULTRASONIC CONTRAST AGENTS AND THEIR PRODUCTION
US4900540A (en) * 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
EP0318081B1 (en) * 1987-11-27 1991-07-24 Akzo N.V. Stabilization of antibodies
IN172208B (en) * 1990-04-02 1993-05-01 Sint Sa

Similar Documents

Publication Publication Date Title
RU93052889A (en) ECHO-CONTRAST MATTER AND METHOD OF ITS PRODUCTION
ATE126708T1 (en) ECHOCONTRAST AGENTS.
ATE38672T1 (en) 7-OXABICYCLOHEPTAN AMINO-SUBSTITUTED PROSTAGLAND-LIKE COMPOUNDS.
RU93042100A (en) NEW 7- (SUBSTITUTED) -8- (SUBSTITUTED) -9 - [(SUBSTITUTED GLYCYL) AMIDO] -6-DEMETHYL-6-DEOXYTETRICINE
ZA837976B (en) Imidazolylalkylthienyl-tetrahydropyridazines and processes for their preparation
IE822648L (en) 7-oxabicycloheptane and 7-oxabicycloheptene compounds.
IT8022782A0 (en) PROCEDURE TO REDUCE THE SOLUBILITY OF ZEOLITE MOLECULAR SIEVES IN AN AQUEOUS SYSTEM.
ES2112859T3 (en) CONTRAST MEANS FOR THE FORMATION OF ECHOGRAPHIC IMAGES.
IE832998L (en) Prostaglandin analogs
AU578783B2 (en) Pyridopyrimidines, several processes for their preparation and their use as medicaments
IT8148348A0 (en) PROCEDURE FOR THE ELECTROLYSIS OF AN AQUEOUS SOLUTION OF KALINO CHLORIDE
EP0304036A3 (en) 3-(substituted)propenyl-7-(aminothiazolylacetamido)ceph-3-em-4-carboxylic acids and esters thereof
CA2224565A1 (en) Agent for combating parasites in farmed fish
RU94037761A (en) Method of synthesis of 3-acylestratrienes and acylbenzenes
JPS5344572A (en) 5-alkoxy-picolic acid, its preparation and hypotensives containing the same
PH24526A (en) Novel imidazo and triazolothiadiazines and medicaments containing same
RU97102193A (en) METHOD FOR PRODUCING DENTAL PLATES FROM COMBINED TRANSPLANT
RU93045690A (en) PREPARATION FOR MASSAGE "MALAVIT"
RU93048526A (en) SUBSTANCE FOR INACTIVATION OF INFLUENZA VIRUS, METHOD FOR ITS OBTAINING AND METHOD FOR ITS USE
IT8322402A0 (en) PROCEDURE FOR THE PREPARATION OF NON-SEDIMENTING AQUEOUS DISPERSIONS.
RU98105699A (en) VODKA "GREAT MAESTRO"
RU93016350A (en) METHOD FOR PRODUCING URENDE DERIVATIVES OF PENICILLIN OR CEFALOSPORIN
RU93015992A (en) METHOD OF DRY RECEPTION OF POSITIVE IMAGE IN PHOTOLITOGRAPHY
TH24381B (en) Substituted benzoyl guanidine, preparation method The use of these substances as drugs or diagnostic substances. And drugs containing these substances
RU93028386A (en) EGG SURFACE TREATMENT METHOD