RU93035094A - METHOD FOR PRODUCING 3- (BENZAZOLYL-) SUBSTITUTED 7-DIETHYLAMINOCUMARINES - Google Patents

METHOD FOR PRODUCING 3- (BENZAZOLYL-) SUBSTITUTED 7-DIETHYLAMINOCUMARINES

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Publication number
RU93035094A
RU93035094A RU93035094/04A RU93035094A RU93035094A RU 93035094 A RU93035094 A RU 93035094A RU 93035094/04 A RU93035094/04 A RU 93035094/04A RU 93035094 A RU93035094 A RU 93035094A RU 93035094 A RU93035094 A RU 93035094A
Authority
RU
Russia
Prior art keywords
producing
diethylaminosalicylic
benzazolylacetic
aldehyde
ethyl ester
Prior art date
Application number
RU93035094/04A
Other languages
Russian (ru)
Other versions
RU2095384C1 (en
Inventor
В.И. Алексеева
О.Л. Калия
Е.А. Лукьянец
Л.Е. Маринина
Л.П. Саввина
И.И. Ткач
Original Assignee
Товарищество с ограниченной ответственностью - Научно-производственная фирма "Бэта"
Filing date
Publication date
Application filed by Товарищество с ограниченной ответственностью - Научно-производственная фирма "Бэта" filed Critical Товарищество с ограниченной ответственностью - Научно-производственная фирма "Бэта"
Priority to RU93035094A priority Critical patent/RU2095384C1/en
Priority claimed from RU93035094A external-priority patent/RU2095384C1/en
Publication of RU93035094A publication Critical patent/RU93035094A/en
Application granted granted Critical
Publication of RU2095384C1 publication Critical patent/RU2095384C1/en

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Claims (1)

Изобретение относится к способу получения кумаринов взаимодействием м-диэтиламиносалицилового альдегида с производными бензазолилуксусной кислоты. Цель: увеличение выхода, упрощение технологии и расширение ассортимента целевых соединений. Конденсацию м-диэтиламиносалицилового альдегида проводят с этиловым эфиром бензазолилуксусной кислоты, образующимся при взаимодействии смеси о-фенилендиамина (или о-аминофенола) и гидрохлорида этилового эфира карбэтоксиацетимида при кипячении в этаноле или других спиртах (пропиловом, изо-пропиловом, бутиловом) в течение 3 ч, без предварительного выделения, в присутствии пиперидина в том же растворителе при кипячении в течение 3,5 ч.The invention relates to a method for producing coumarins by reacting m-diethylaminosalicylic aldehyde with benzazolylacetic acid derivatives. Goal: increase yield, simplify technology and expand the range of target compounds. Condensation of m-diethylaminosalicylic aldehyde is carried out with benzazolylacetic acid ethyl ester, which is formed by the reaction of a mixture of o-phenylenediamine (or o-aminophenol) and carbethoxyacetimide ethyl ester hydrochloride during boiling in ethanol or other butyl propyl alcohol, butyl alcohol, , without preliminary isolation, in the presence of piperidine in the same solvent while boiling for 3.5 hours
RU93035094A 1993-07-06 1993-07-06 Method for production of 3-(benzazolyl-) substituted-7-diethylaminocoumarines RU2095384C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU93035094A RU2095384C1 (en) 1993-07-06 1993-07-06 Method for production of 3-(benzazolyl-) substituted-7-diethylaminocoumarines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU93035094A RU2095384C1 (en) 1993-07-06 1993-07-06 Method for production of 3-(benzazolyl-) substituted-7-diethylaminocoumarines

Publications (2)

Publication Number Publication Date
RU93035094A true RU93035094A (en) 1996-10-10
RU2095384C1 RU2095384C1 (en) 1997-11-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU93035094A RU2095384C1 (en) 1993-07-06 1993-07-06 Method for production of 3-(benzazolyl-) substituted-7-diethylaminocoumarines

Country Status (1)

Country Link
RU (1) RU2095384C1 (en)

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