RU93004982A - Способ лечения эндотоксинового шока с применением антиадгезивных антител - Google Patents

Способ лечения эндотоксинового шока с применением антиадгезивных антител

Info

Publication number
RU93004982A
RU93004982A RU93004982/14A RU93004982A RU93004982A RU 93004982 A RU93004982 A RU 93004982A RU 93004982/14 A RU93004982/14 A RU 93004982/14A RU 93004982 A RU93004982 A RU 93004982A RU 93004982 A RU93004982 A RU 93004982A
Authority
RU
Russia
Prior art keywords
endotoxin shock
anti adhesive
treating endotoxin
adhesive antibodies
antibodies
Prior art date
Application number
RU93004982/14A
Other languages
English (en)
Other versions
RU2123861C1 (ru
Inventor
Гордон Леттс Линдсей
М.Уэлдон Стивен
Дж.Поссанца Дженус
Original Assignee
Берингер Ингельгейм Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Берингер Ингельгейм Фармасьютикалз, Инк. filed Critical Берингер Ингельгейм Фармасьютикалз, Инк.
Publication of RU93004982A publication Critical patent/RU93004982A/ru
Application granted granted Critical
Publication of RU2123861C1 publication Critical patent/RU2123861C1/ru

Links

Claims (1)

  1. Настоящее изобретение касается нового способа лечения пациента, страдающего от эндотоксинового штока, предусматривающего введение анти-СД18 антитела или анти-ICAM-1 антитела, или их фрагментов.
RU93004982A 1990-08-31 1991-08-30 Способ лечения эндотоксинового шока с применением антиадгезивных антител RU2123861C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57913790A 1990-08-31 1990-08-31
US07/579,137 1990-08-31

Publications (2)

Publication Number Publication Date
RU93004982A true RU93004982A (ru) 1995-09-10
RU2123861C1 RU2123861C1 (ru) 1998-12-27

Family

ID=24315708

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93004982A RU2123861C1 (ru) 1990-08-31 1991-08-30 Способ лечения эндотоксинового шока с применением антиадгезивных антител

Country Status (11)

Country Link
EP (1) EP0546076B1 (ru)
JP (1) JPH06501931A (ru)
AT (1) ATE166230T1 (ru)
AU (1) AU645348B2 (ru)
CA (1) CA2090464A1 (ru)
DE (1) DE69129460T2 (ru)
DK (1) DK0546076T3 (ru)
ES (1) ES2115618T3 (ru)
HU (1) HU216097B (ru)
RU (1) RU2123861C1 (ru)
WO (1) WO1992004034A1 (ru)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629162A (en) * 1991-06-11 1997-05-13 The Center For Blood Research Method of identifying agents which modulate ICAM-3 binding to LFA-1
GB9115364D0 (en) * 1991-07-16 1991-08-28 Wellcome Found Antibody
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
CA2107097A1 (en) * 1992-01-27 1993-07-28 Michael W. Gallatin Icam-related protein
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US5852170A (en) * 1992-01-27 1998-12-22 Icos Corporation ICAM-4 materials and methods
US5811517A (en) * 1992-01-27 1998-09-22 Icos Corporation ICAM-related protein variants
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5700658A (en) * 1992-01-27 1997-12-23 Icos Corporation ICAM-4 materials and methods
US5702917A (en) * 1992-01-27 1997-12-30 Icos Corporation Polynucleotides encoding human ICAM-4
US5773293A (en) * 1992-01-27 1998-06-30 Icos Corporation Anti-ICAM-4 antibodies and hybridomas
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US5753502A (en) * 1993-08-05 1998-05-19 Icos Corporation Neuron-specific ICAM-4 promoter
JPH06511156A (ja) 1992-07-16 1994-12-15 イコス　コーポレイション 炎症性疾患状態に関連する症状の緩和
US5854070A (en) * 1992-07-16 1998-12-29 Icos Corporation Murine and humanizer 23F2G antibodies and cell lines expressing said antibodies
AU687755B2 (en) * 1992-08-21 1998-03-05 Genentech Inc. Method for treating an LFA-1-mediated disorder
US5695760A (en) * 1995-04-24 1997-12-09 Boehringer Inglehiem Pharmaceuticals, Inc. Modified anti-ICAM-1 antibodies and their use in the treatment of inflammation
JP3813450B2 (ja) * 2000-02-29 2006-08-23 古河電気工業株式会社 半導体レーザ素子

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0314863B1 (en) * 1987-11-02 1994-12-07 Baylor College Of Medicine Use of ICAM-1 or its functional derivatives for the treatment of non-specific inflammation
US5147637A (en) * 1988-06-07 1992-09-15 The Rockefeller University Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma

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