RU93004828A - SALTS FORMED BY RANITIDINE AND COMPLEX COMPOUND OF BISMUTH WITH CARBONIC ACID, PHARMACEUTICAL PRODUCT - Google Patents

SALTS FORMED BY RANITIDINE AND COMPLEX COMPOUND OF BISMUTH WITH CARBONIC ACID, PHARMACEUTICAL PRODUCT

Info

Publication number
RU93004828A
RU93004828A RU93004828/04A RU93004828A RU93004828A RU 93004828 A RU93004828 A RU 93004828A RU 93004828/04 A RU93004828/04 A RU 93004828/04A RU 93004828 A RU93004828 A RU 93004828A RU 93004828 A RU93004828 A RU 93004828A
Authority
RU
Russia
Prior art keywords
ranitidine
bismuth
salts formed
salts
carbonic acid
Prior art date
Application number
RU93004828/04A
Other languages
Russian (ru)
Other versions
RU2114857C1 (en
Inventor
Уотсон Клитроу Джон
Original Assignee
Глэксо Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888817098A external-priority patent/GB8817098D0/en
Application filed by Глэксо Груп Лимитед filed Critical Глэксо Груп Лимитед
Publication of RU93004828A publication Critical patent/RU93004828A/en
Application granted granted Critical
Publication of RU2114857C1 publication Critical patent/RU2114857C1/en

Links

Claims (1)

Изобретение относится к солям, образованным ранитидином и комплексом висмута с карбоновой кислотой, и сольватам этих солей. Примеры приемлемых карбоновых кислот включают: лимонную кислоту, винную кислоту и агарициновую кислоту. Соли применимы для лечения желудочно-кишечных нарушений, в частности, состояний, относящихся к желудку и двенадцатиперстной кишке. Соли проявляют антисекреторную активность, характерную для ранитидина, в сочетании с бактерицидной активностью к Campylobacter pylori и они также обладают цитозащитными свойствами.The invention relates to salts formed by ranitidine and a complex of bismuth with a carboxylic acid, and solvates of these salts. Examples of suitable carboxylic acids include: citric acid, tartaric acid and agaricic acid. Salts are useful for the treatment of gastrointestinal disorders, in particular conditions related to the stomach and duodenum. The salts exhibit the antisecretory activity characteristic of ranitidine in combination with the bactericidal activity of Campylobacter pylori and they also have cytotoxic properties.
RU93004828A 1988-07-18 1993-04-19 Salts formed by ranitidine and bismuth chelate compound with carboxylic acid and pharmaceutical preparation RU2114857C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888817098A GB8817098D0 (en) 1988-07-18 1988-07-18 Chemical compounds
GB8817098.0 1989-03-01
GB8904686.6 1989-03-01

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU4614571 Division

Publications (2)

Publication Number Publication Date
RU93004828A true RU93004828A (en) 1997-01-20
RU2114857C1 RU2114857C1 (en) 1998-07-10

Family

ID=10640673

Family Applications (2)

Application Number Title Priority Date Filing Date
SU4614571 RU2029767C1 (en) 1988-07-18 1989-07-17 Process for preparing salt formed by ranitidine and bismuth-carboxylic acid complex
RU93004828A RU2114857C1 (en) 1988-07-18 1993-04-19 Salts formed by ranitidine and bismuth chelate compound with carboxylic acid and pharmaceutical preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SU4614571 RU2029767C1 (en) 1988-07-18 1989-07-17 Process for preparing salt formed by ranitidine and bismuth-carboxylic acid complex

Country Status (4)

Country Link
GB (1) GB8817098D0 (en)
RU (2) RU2029767C1 (en)
SA (1) SA90100090B1 (en)
ZA (1) ZA895418B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2555360C2 (en) * 2012-11-06 2015-07-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Method for measuring water in complex compounds

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