RU92016459A -
E.COLI, PROTEIN, DNA
- Google Patents
E.COLI, PROTEIN, DNA
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Publication number
RU92016459A
RU92016459ARU92016459/13ARU92016459ARU92016459ARU 92016459 ARU92016459 ARU 92016459ARU 92016459/13 ARU92016459/13 ARU 92016459/13ARU 92016459 ARU92016459 ARU 92016459ARU 92016459 ARU92016459 ARU 92016459A
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Application filed by Дзе Дженерал Хоспитал КорпорейшнfiledCriticalДзе Дженерал Хоспитал Корпорейшн
Publication of RU92016459ApublicationCriticalpatent/RU92016459A/en
Изобретение описывает штаммы Е.соli, способные к высокого уровня стабильной экспрессии гетерологичных белков вследствие мутаций, приводящих к снижению скорости деградации гетерологических белков. Предложены также рекомбинантные белки, экспрессируемые мутантами E.coli, и ДНК, несущая мутации.The invention describes E. coli strains capable of a high level of stable expression of heterologous proteins due to mutations leading to a decrease in the rate of degradation of heterologous proteins. Recombinant proteins expressed by E. coli mutants and DNA carrying mutations are also proposed.
RU92016459/13A1990-05-021991-05-02
E.COLI, PROTEIN, DNA
RU92016459A
(en)
PROTEIN SO PRODUCED. A RECOMBINANT PLASMID, A TRANSFORMING MICROORGANISM, A SEGMENT OF POLIDEOXYRIBONUCLEOTIDE, A PROCESS TO PRODUCE A BIOLOGICALLY ACTIVE PROTEIN AND THE