EP0273916A4 - Pulmonary hydrophobic surfactant-associated protein of 6,000 daltons molecular weight and multimers thereof. - Google Patents

Pulmonary hydrophobic surfactant-associated protein of 6,000 daltons molecular weight and multimers thereof.

Info

Publication number
EP0273916A4
EP0273916A4 EP19860906670 EP86906670A EP0273916A4 EP 0273916 A4 EP0273916 A4 EP 0273916A4 EP 19860906670 EP19860906670 EP 19860906670 EP 86906670 A EP86906670 A EP 86906670A EP 0273916 A4 EP0273916 A4 EP 0273916A4
Authority
EP
European Patent Office
Prior art keywords
multimers
pulmonary
molecular weight
associated protein
hydrophobic surfactant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19860906670
Other languages
German (de)
French (fr)
Other versions
EP0273916A1 (en
Inventor
Jeffrey A Whitsett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cincinnati Childrens Hospital Medical Center
Original Assignee
Cincinnati Childrens Hospital Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cincinnati Childrens Hospital Medical Center filed Critical Cincinnati Childrens Hospital Medical Center
Publication of EP0273916A1 publication Critical patent/EP0273916A1/en
Publication of EP0273916A4 publication Critical patent/EP0273916A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6884—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP19860906670 1986-05-06 1986-10-24 Pulmonary hydrophobic surfactant-associated protein of 6,000 daltons molecular weight and multimers thereof. Withdrawn EP0273916A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86023986A 1986-05-06 1986-05-06
US860239 2001-05-18

Publications (2)

Publication Number Publication Date
EP0273916A1 EP0273916A1 (en) 1988-07-13
EP0273916A4 true EP0273916A4 (en) 1989-11-30

Family

ID=25332781

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19860906670 Withdrawn EP0273916A4 (en) 1986-05-06 1986-10-24 Pulmonary hydrophobic surfactant-associated protein of 6,000 daltons molecular weight and multimers thereof.

Country Status (3)

Country Link
EP (1) EP0273916A4 (en)
JP (1) JPS63503222A (en)
WO (1) WO1987006943A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430020A (en) * 1984-12-11 1995-07-04 Scios Nova Inc. Recombinant alveolar surfactant protein
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US5169761A (en) * 1984-12-11 1992-12-08 California Biotechnology Inc. Dna encoding and expression systems for alveolar surfactant proteins
US5840527A (en) * 1984-12-11 1998-11-24 Byk Gulden Lomberg Chemische Fabrik Gmbh Recombinant alveolar surfactant protein
IT1203873B (en) * 1987-04-08 1989-02-23 Chiesi Farma Spa PHARMACEUTICAL COMPOSITIONS THAT THE NATURAL PULMONARY SURFACTANT CONTAIN. PREPARATION METHOD E
WO1989000167A1 (en) * 1987-07-01 1989-01-12 Kabigen Ab Proteins and protein compositions and their use
US5164369A (en) * 1988-01-06 1992-11-17 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
US6613734B2 (en) 1988-01-06 2003-09-02 The Scripps Research Institute Peptides-containing liposomal surfactants
AU3073789A (en) * 1988-03-31 1989-10-05 Abbott Laboratories Drug delivery using pulmonary surfactant to facilitate absorption
SE8803713D0 (en) * 1988-10-18 1988-10-18 Kabigen Ab BIOLOGICALLY ACTIVE LIPOPROTEIN AND ITS USE
EP0458167B1 (en) * 1990-05-21 1997-04-23 Abbott Laboratories Fatty acid-pulmonary surfactant conjugates
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
JPH05294996A (en) * 1992-04-17 1993-11-09 Tokyo Tanabe Co Ltd Synthetic peptides, lung surfactant containing the same and therapeutic agents for respiration distress syndrome
US5958902A (en) 1997-04-16 1999-09-28 Wisconsin Alumni Research Foundation Method and composition for treating sleep apnea
AU6083899A (en) 1999-09-16 2001-04-17 Aventis Behring Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
ES2346048T3 (en) 2001-10-11 2010-10-08 Nycomed Gmbh NEW USE OF A PULMONARY TENSIOACTIVE AGENT.
WO2006013183A1 (en) 2004-08-06 2006-02-09 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
US9289388B2 (en) 2008-12-10 2016-03-22 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003408A1 (en) * 1984-12-11 1986-06-19 California Biotechnology Inc. Recombinant alveolar surfactant protein
WO1987002037A1 (en) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Pulmonary surfactant proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4113711A (en) * 1976-01-19 1978-09-12 Said Sami I Vasoactive lung polypeptides
US4220642A (en) * 1978-09-07 1980-09-02 Viktor Mutt Vasoactive lung polypeptides
JPS61501761A (en) * 1984-10-05 1986-08-21 ザ　ダウ　ケミカル　カンパニ− Improved molding method for semi-finished products for solid phase molding of thermoplastic articles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003408A1 (en) * 1984-12-11 1986-06-19 California Biotechnology Inc. Recombinant alveolar surfactant protein
WO1987002037A1 (en) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Pulmonary surfactant proteins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO8706943A1 *

Also Published As

Publication number Publication date
EP0273916A1 (en) 1988-07-13
WO1987006943A1 (en) 1987-11-19
JPS63503222A (en) 1988-11-24

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19880517

A4 Supplementary search report drawn up and despatched

Effective date: 19891130

17Q First examination report despatched

Effective date: 19910507

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19940820

RIN1 Information on inventor provided before grant (corrected)

Inventor name: WHITSETT, JEFFREY, A.