RU92004370A - PHTHALASINE DERIVATIVES, METHOD OF THEIR PRODUCTION AND MEDICINES ON THEIR BASIS - Google Patents

PHTHALASINE DERIVATIVES, METHOD OF THEIR PRODUCTION AND MEDICINES ON THEIR BASIS

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Publication number
RU92004370A
RU92004370A RU92004370/04A RU92004370A RU92004370A RU 92004370 A RU92004370 A RU 92004370A RU 92004370/04 A RU92004370/04 A RU 92004370/04A RU 92004370 A RU92004370 A RU 92004370A RU 92004370 A RU92004370 A RU 92004370A
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RU
Russia
Prior art keywords
residue
alkyl
pyridyl
phenyl
substituted
Prior art date
Application number
RU92004370/04A
Other languages
Russian (ru)
Inventor
Шеффлер Герхард
Фляйшхауэр Илона
Уучер Бернхард
Энгель Юрген
Селеньи Штефан
Вернер Ульрих
Original Assignee
Аста Медика Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аста Медика Аг filed Critical Аста Медика Аг
Publication of RU92004370A publication Critical patent/RU92004370A/en

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Claims (1)

Предложены фармакологически эффективные производные фталазина общей формулы (I)
Figure 00000001

где Х обозначает кислород или серу и остаток R представляет остаток хинуклидила, С1 - С6 -алкильный остаток, остаток фенила, остаток пиридила, замещенный остатками R1, R2 и/или R3 остаток фенила или пиридила, замещенный пиридилом или алкилпиридилом С1 - С6 -алкильный остаток или замещенный фенилом С1 - С6 -алкильный остаток, причем этот остаток фенила может быть замещен также остатками R1, R2 и/или R3, и остатки R1, R2 и R3 одинаковые или различные и обозначают водород, галоген, ригалогенметил, С1 - С6-алкил, С1 - С6 -алкокси, карбокси, карб-С1 - С6 -алкокси, амино, С1 - С6 -алкиламино, С1 - С6 -диалкиламино, С1 - С6 -триалкиламино, С2 - С6 - алканоиламино или С2 - С6 -алканоиламино, который в алкильной части содержит еще аминогруппу, и их физиологически совместимые кислые аддитивные соли, способ их получения и лекарственное средство на их основе.Pharmacologically effective phthalazine derivatives of general formula (I) are provided.
Figure 00000001

where X is oxygen or sulfur and the residue R represents a quinuclidyl residue, a C 1 -C 6 -alkyl residue, a phenyl residue, a pyridyl residue substituted by R 1 , R 2 and / or R 3 residues of a phenyl or pyridyl residue substituted by pyridyl or alkyl pyridyl C 1 - C 6 -alkyl residue or substituted with phenyl C 1 - C 6 -alkyl residue, and this phenyl residue may also be substituted by residues R 1 , R 2 and / or R 3 , and residues R 1 , R 2 and R 3 are the same or different and denote hydrogen, halogen, rihalogenmethyl, C 1 - C 6 -alkyl, C 1 - C 6 -alkoxy, carboxy, carb-C 1 - C 6 -alko Xi, amino, C 1 - C 6 alkylamino, C 1 - C 6 dialkylamino, C 1 - C 6 -trialkilamino, C 2 - C 6 - alkanoylamino or C 2 - C 6 alkanoylamino which the alkyl portion contains more an amino group, and their physiologically compatible acid addition salts, a method for their preparation and a medicament based thereon.
RU92004370/04A 1991-10-31 1992-10-30 PHTHALASINE DERIVATIVES, METHOD OF THEIR PRODUCTION AND MEDICINES ON THEIR BASIS RU92004370A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEP4135910.0 1991-10-31

Publications (1)

Publication Number Publication Date
RU92004370A true RU92004370A (en) 1995-08-20

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