RU92004314A - COMPLEX SALTS OF HEMATOPORPHIRIN AND ITS DERIVATIVES, METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL AGENT - Google Patents
COMPLEX SALTS OF HEMATOPORPHIRIN AND ITS DERIVATIVES, METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL AGENTInfo
- Publication number
- RU92004314A RU92004314A RU92004314/04A RU92004314A RU92004314A RU 92004314 A RU92004314 A RU 92004314A RU 92004314/04 A RU92004314/04 A RU 92004314/04A RU 92004314 A RU92004314 A RU 92004314A RU 92004314 A RU92004314 A RU 92004314A
- Authority
- RU
- Russia
- Prior art keywords
- carboxy
- ethylamine
- group
- complex salts
- propylamine
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 239000008177 pharmaceutical agent Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims 3
- 239000011780 sodium chloride Substances 0.000 claims 3
- UJKPHYRXOLRVJJ-MLSVHJFASA-N CC(O)C1=C(C)/C2=C/C3=N/C(=C\C4=C(CCC(O)=O)C(C)=C(N4)/C=C4\N=C(\C=C\1/N\2)C(C)=C4C(C)O)/C(CCC(O)=O)=C3C Chemical class CC(O)C1=C(C)/C2=C/C3=N/C(=C\C4=C(CCC(O)=O)C(C)=C(N4)/C=C4\N=C(\C=C\1/N\2)C(C)=C4C(C)O)/C(CCC(O)=O)=C3C UJKPHYRXOLRVJJ-MLSVHJFASA-N 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- -1 1-carboxy-5-aminopentyl Chemical group 0.000 claims 1
- KYNMONSTYCGIDJ-UHFFFAOYSA-N 2-amino-3-(1H-indol-2-yl)propanoic acid Chemical compound C1=CC=C2NC(CC(N)C(O)=O)=CC2=C1 KYNMONSTYCGIDJ-UHFFFAOYSA-N 0.000 claims 1
- QNAYBMKLOCPYGJ-UHFFFAOYSA-N DL-alanine Chemical compound CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 claims 1
- CKLJMWTZIZZHCS-UHFFFAOYSA-N DL-aspartic acid Chemical compound OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N DL-cysteine Chemical compound SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N DL-glutamic acid Chemical compound OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N DL-glutamine Chemical compound OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N DL-isoleucine Chemical compound CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N DL-phenylalanine Chemical compound OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N DL-serine Chemical compound OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N DL-threonine Chemical compound CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N DL-tyrosine Chemical compound OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N DL-valine Chemical compound CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 229960003569 Hematoporphyrin Drugs 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- LRQKBLKVPFOOQJ-UHFFFAOYSA-N Norleucine Chemical compound CCCCC(N)C(O)=O LRQKBLKVPFOOQJ-UHFFFAOYSA-N 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N glycine Chemical group NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
Claims (1)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL91292220A PL165249B1 (en) | 1991-10-29 | 1991-10-29 | Method op obtaining complex salts of hematporphyrine and its derivatives |
PLP-292220 | 1991-10-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU92004314A true RU92004314A (en) | 1995-05-20 |
RU2122003C1 RU2122003C1 (en) | 1998-11-20 |
Family
ID=20055985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU92004314/04A RU2122003C1 (en) | 1991-10-29 | 1992-10-28 | Complex salt of hematoporphyrine and derivatives thereof, mixture of complex salts of hematoporhyrine and derivatives thereof, method of preparing complex salts, method of preparing mixture of complex salts, and pharmaceutical composition |
Country Status (18)
Country | Link |
---|---|
US (1) | US5451599A (en) |
EP (1) | EP0539960B1 (en) |
JP (1) | JP3020759B2 (en) |
CN (1) | CN1040328C (en) |
BG (1) | BG61648B1 (en) |
CA (1) | CA2081605C (en) |
CZ (1) | CZ281694B6 (en) |
DE (1) | DE69217819T2 (en) |
DK (1) | DK0539960T3 (en) |
FI (1) | FI100243B (en) |
HR (1) | HRP921337B1 (en) |
LV (1) | LV11952B (en) |
NO (1) | NO300499B1 (en) |
PL (1) | PL165249B1 (en) |
RU (1) | RU2122003C1 (en) |
SI (1) | SI9200286B (en) |
UA (1) | UA40568C2 (en) |
YU (1) | YU48961B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO180167C (en) * | 1994-09-08 | 1997-02-26 | Photocure As | Photochemical method for introducing molecules into the cytosol of cells |
US5948771A (en) * | 1996-01-31 | 1999-09-07 | The Trustees Of Columbia University In The City Of New York | Method for treating heart failure using tetrapyrroles and metallotetrapyrroles |
GB9606293D0 (en) * | 1996-03-26 | 1996-05-29 | William Harvey Research Limite | Treatment of cancers and other tumours |
AU2210402A (en) | 2000-11-29 | 2002-06-11 | Norwegian Radium Hospital Res | Photochemical internalization for virus-mediated molecule delivery into the cyosol |
KR20080080685A (en) | 2000-11-29 | 2008-09-04 | 피씨아이 바이오테크 에이에스 | Photochemical internalization for delivery of molecules into the cytosol |
CN104130266A (en) * | 2013-05-02 | 2014-11-05 | 中国医学科学院生物医学工程研究所 | Novel protoporphyrin derivative and preparation method thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2912M (en) * | 1963-07-24 | 1964-11-09 | Rech S Pharma E R P H A R Soc | Procaine hematoporphyrinate dihydrochloride. |
EP0220686B1 (en) * | 1985-10-23 | 1992-12-30 | Nihon Medi-Physics Co., Ltd. | Porphyrin derivatives, and their production and use |
US4882234A (en) * | 1986-11-12 | 1989-11-21 | Healux, Inc. | Storage-stable porphin compositions and a method for their manufacture |
US4968715A (en) * | 1988-07-06 | 1990-11-06 | Health Research, Inc. | Use of purified hematoporphyrin trimers in photodynamic therapy |
US5190966A (en) * | 1988-07-06 | 1993-03-02 | Health Research, Inc. | Purified hematoporphyrin dimers and trimers useful in photodynamic therapy |
US4961920A (en) * | 1988-12-08 | 1990-10-09 | Luminis Pty, Ltd. | Phototherapeutic monovinyl and divinyl ether-linked dimers |
CN102565846B (en) * | 2011-12-30 | 2014-05-14 | 清华大学 | Honeycomb-type thermal neutron detector |
-
1991
- 1991-10-29 PL PL91292220A patent/PL165249B1/en not_active IP Right Cessation
-
1992
- 1992-10-26 FI FI924856A patent/FI100243B/en not_active IP Right Cessation
- 1992-10-28 CA CA002081605A patent/CA2081605C/en not_active Expired - Lifetime
- 1992-10-28 EP EP92118447A patent/EP0539960B1/en not_active Expired - Lifetime
- 1992-10-28 DE DE69217819T patent/DE69217819T2/en not_active Expired - Lifetime
- 1992-10-28 DK DK92118447.9T patent/DK0539960T3/en active
- 1992-10-28 NO NO924151A patent/NO300499B1/en not_active IP Right Cessation
- 1992-10-28 BG BG97030A patent/BG61648B1/en unknown
- 1992-10-28 RU RU92004314/04A patent/RU2122003C1/en not_active IP Right Cessation
- 1992-10-29 YU YU94592A patent/YU48961B/en unknown
- 1992-10-29 JP JP4291322A patent/JP3020759B2/en not_active Expired - Lifetime
- 1992-10-29 CN CN92112561A patent/CN1040328C/en not_active Expired - Fee Related
- 1992-10-29 US US07/968,434 patent/US5451599A/en not_active Expired - Lifetime
- 1992-10-29 SI SI9200286A patent/SI9200286B/en not_active IP Right Cessation
- 1992-10-29 CZ CS923252A patent/CZ281694B6/en not_active IP Right Cessation
- 1992-11-24 HR HRP-945A patent/HRP921337B1/en not_active IP Right Cessation
-
1993
- 1993-06-15 UA UA93002921A patent/UA40568C2/en unknown
-
1997
- 1997-06-05 LV LVP-97-110A patent/LV11952B/en unknown
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