RU92001064A - METHOD OF MODELING THE SECONDARY IMMUNODEFICIENCY CONDITION - Google Patents

METHOD OF MODELING THE SECONDARY IMMUNODEFICIENCY CONDITION

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Publication number
RU92001064A
RU92001064A RU92001064/14A RU92001064A RU92001064A RU 92001064 A RU92001064 A RU 92001064A RU 92001064/14 A RU92001064/14 A RU 92001064/14A RU 92001064 A RU92001064 A RU 92001064A RU 92001064 A RU92001064 A RU 92001064A
Authority
RU
Russia
Prior art keywords
modeling
secondary immunodeficiency
immunodeficiency state
development
invention allows
Prior art date
Application number
RU92001064/14A
Other languages
Russian (ru)
Other versions
RU2050020C1 (en
Inventor
Е.П. Москаленко
С.И. Ильина
С.Ф. Уразовский
З.Т. Тагиров
Original Assignee
Е.П. Москаленко
С.И. Ильина
С.Ф. Уразовский
З.Т. Тагиров
Filing date
Publication date
Application filed by Е.П. Москаленко, С.И. Ильина, С.Ф. Уразовский, З.Т. Тагиров filed Critical Е.П. Москаленко
Priority to RU92001064A priority Critical patent/RU2050020C1/en
Priority claimed from RU92001064A external-priority patent/RU2050020C1/en
Publication of RU92001064A publication Critical patent/RU92001064A/en
Application granted granted Critical
Publication of RU2050020C1 publication Critical patent/RU2050020C1/en

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Claims (1)

Способ моделирования вторичного иммунодефицитного состояния относится к медицине, преимущественно к иммунологии, и может найти применение при моделировании недостаточности иммунной системы по тимусзависимому типу для изучения патогенетических механизмов развития вторичного иммунодефицитного состояния, разработки новых методов лечения, принципов лекарственной иммунокоррекции. Изобретение позволяет упростить метод и повысить воспроизводимость модели вторичного иммунодефицитного состояния. Для этого подопытным животным вводят коклюшную агглютинирующую сыворотку в дозе 0,10 мл однократно внутрибрюшинно. Применение изобретения позволяет значительно упростить способ и исключить вариабельность результатов за счет использования стандартного препарата.The method of modeling a secondary immunodeficiency state relates to medicine, primarily immunology, and can be used in modeling a deficiency of the immune system of a thymus-dependent type to study the pathogenetic mechanisms of the development of a secondary immunodeficiency state, the development of new treatments, and the principles of drug immunocorrection. The invention allows to simplify the method and improve the reproducibility of the model of the secondary immunodeficiency state. For this purpose, pertussis agglutinating serum is administered in experimental animals at a dose of 0.10 ml intraperitoneally once. The use of the invention allows to significantly simplify the method and eliminate the variability of results due to the use of a standard preparation.
RU92001064A 1992-10-16 1992-10-16 Method for modeling secondary immunodeficiency state of t- cell type RU2050020C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU92001064A RU2050020C1 (en) 1992-10-16 1992-10-16 Method for modeling secondary immunodeficiency state of t- cell type

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU92001064A RU2050020C1 (en) 1992-10-16 1992-10-16 Method for modeling secondary immunodeficiency state of t- cell type

Publications (2)

Publication Number Publication Date
RU92001064A true RU92001064A (en) 1995-05-20
RU2050020C1 RU2050020C1 (en) 1995-12-10

Family

ID=20130603

Family Applications (1)

Application Number Title Priority Date Filing Date
RU92001064A RU2050020C1 (en) 1992-10-16 1992-10-16 Method for modeling secondary immunodeficiency state of t- cell type

Country Status (1)

Country Link
RU (1) RU2050020C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2644539C2 (en) * 2016-03-28 2018-02-12 Федеральное государственное бюджетное образовательное учреждение высшего образования "Тихоокеанский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО ТГМУ Минздрава России) Method for secondary immunodeficiency simulation for small laboratory animals

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