RU62527U1 - FLOW TRANSMEMBRANE DIALYSING COMPLEX - Google Patents

Abstract

The utility model relates to medicine, in particular to surgery, and can be used in the local treatment of infected wounds and purulent cavities. The essence of the utility model is that in a flowing transmembrane dialysis complex, the container with the dialysis solution and the container with spent dialysate are interconnected by means of an elastic duct pipe, as a result of which a vacuum is created in the tank for spent dialysate, which ensures effective dialysis. The application of the proposed dialysis complex does not require special energy-intensive equipment and allows for effective local detoxification of open and closed infected cavities both in stationary and in extreme conditions of peacetime and war.

Description

The utility model relates to medicine, in particular to surgery, and can be used in the local treatment of infected wounds, purulent-septic diseases of soft tissues, abdominal cavity, retroperitoneal space, hollow organs and cavities.

The known method of wound dialysis using drainage from a semipermeable membrane that provides, on the one hand, stable diffusion of drugs in the body tissue, and on the other, the removal of toxic products from the wound cavity [1]. The method is widely used in various fields of surgery, but it is ineffective, since it does not provide for the circulation of dialysate in the cavity of the membrane capsule. In addition, the replacement of the spent dialysate solution with a new one in the known method is carried out by repeatedly removing the membrane capsule from the wound, which leads to disruption of reparative processes in the wound.

A dialysis device is also described in the transmembrane dialysis method in coloproctology [2]. The device consists of a standard double-lumen tube, on which a piece of a cellulose tubular casing is hermetically fixed. The cavity created in this way communicates with the external environment through the narrow channel of the double-lumen tube, which is muffled at one end and has 2-3 openings under the shell. At the second end of the canal, a segment of the subclavian catheter with a plug is fixed. Through it, medicinal substances are introduced into the cavity of the membrane membrane. However, the known dialysis drainage does not provide continuous tissue detoxification, since every 4-6 hours it is necessary to re-introduce the dialysis solution into

the membrane. The device does not provide for the circulation of dialysate in the cavity of the membrane capsule, which also reduces its effectiveness.

Closest to the proposed model in technical essence is a device for conducting transmembrane dialysis of the stuffing bag in patients with pancreatic necrosis, including a container with a dialysis solution, a membrane dialyzer installed in a stuffing bag, a microperistaltic pump and a container with spent dialysate [3]. Using this device, the dialysate solution is pumped through the inlet tube into the membrane capsule, and the spent dialysate from the capsule is actively aspirated through the outlet tube. Known dialysis device provides a fairly effective detoxification of tissues, however, it is energy-intensive, technically complex and can only be used in stationary conditions.

The objective of the utility model is to create a reliable, cost-effective dialysis device that provides effective dialysis of both open and closed infected cavities.

The task is achieved in that in a flowing transmembrane dialysis complex, which includes a system for introducing a dialysate solution into a membrane capsule installed in an infected cavity, and a waste dialysate removal system, a dialysis solution container and a spent dialysate container are interconnected by means of an elastic air duct. This allows you to create a vacuum in the container for spent dialysate, providing effective dialysis. The tube for feeding the dialysate solution and the tube for draining the spent dialysate are brought directly to the membrane capsule and are fixed on it.

The essence of the utility model is illustrated in the drawing.

Figure 1 shows the drainage installation, which consists of three pyrogen-free elastic tubes - (1), (2), (3), a container with a dialysate solution (4) and a container for spent dialysate (5). Capacity with

the dialysate solution (4) is installed upside down above the infected cavity (6) of the patient on a standard stand (8) for the dropper. The spent dialysate container (5) is installed below the container with the dialysate solution (4), for example on the floor. Tanks (4) and (5) are standard 400 ml glass bottles. Directly in the infected cavity (6) is a membrane capsule (7), to which a supply tube (1) and a discharge tube (2) are connected and sealed on both sides. The container (4) communicates with the cavity of the membrane capsule (7) by means of a supply pipe (1) through which the dialysate solution enters the membrane capsule (7). The spent dialysate from the membrane capsule (7) through the discharge tube (2) enters the container for spent dialysate (5). An elastic tube (3) serving as an air duct connects the air space of containers (4) and (5) to each other. The tube (1) has a clamp (9) for regulating the dialysate current into the cavity of the membrane capsule (7). The clamp (10) on the tube (2) controls the current of spent dialysate from the membrane capsule (7). The air duct (3) is also provided with a clamp (11).

Elastic pyrogen-free tubes (1), (2) and (3) are made of polyvinyl chloride. Any type of semipermeable membrane can be used as a membrane capsule, but the most effective are dialysis tubular membranes made of synthetically modified cellulose (SMC) with a lumen diameter of 20 mm, a pore size of 3.0 nm, manufactured by Sigma-Aldrich Fine Chemicals (USA).

The principle of operation of the proposed dialysis unit is based on the creation of negative pressure in the spent dialysate container (5), which ensures effective outflow of spent dialysate from the membrane capsule (7). Since the container with the dialysate solution (4) and the spent dialysate container (5) are interconnected by an air pipe (3), negative pressure in the container (5) is ensured by creating a vacuum in the tank upside down (4), which

occurs when the dialysis solution enters the membrane capsule (7) under the influence of gravity.

The dialysis complex works as follows.

The end of the supply pipe (1) is hermetically fixed at the upper pole of the membrane capsule (7) located in the infected cavity of the patient, and the end of the tube (2) for the outflow of spent dialysate is hermetically fixed at the lower pole of the membrane capsule (7). Clamp (11) block the tube-duct (3) to prevent the ingestion of a dialysate solution. Open the clamp (9) on the inlet tube (1), and then open the clamp (12) on the tube-duct (3). After the cavity of the membrane capsule (7) is completely filled with a dialysis solution, the clamp (10) sets the necessary outflow rate of spent dialysate from the capsule (7). After the preparatory operations, the dialysate solution from the container (4) through the inlet tube (1) begins to enter the membrane capsule (7) installed in the infected cavity (6), and the spent dialysate through the outlet tube (2) begins to be actively discharged into the container (5 )

The cycle is repeated with the frequency and duration set by the doctor. The therapeutic effect of dialysis drainage from a semipermeable membrane is ensured by the controlled administration of a drug solution into the cavity of a semipermeable membrane capsule, through the pores of which it enters the infected cavity of the patient, and the controlled outflow of spent dialysate from it. Any osmotically active substance can be used as a dialysate, but the most effective is the use of chitosan ascorbate. The effectiveness of therapeutic drainage in a clinical setting can be judged by the results of clinical and laboratory studies, as well as by the well-being of the patient.

The technical result obtained by the implementation of the described dialysis complex:

creation of optimal conditions in a wound for preserving and activating the natural mechanisms of antimicrobial protection, purification and regeneration;

continuous uniform diffusion in the tissue of medicinal substances;

continuous tissue detoxification;

a decrease in the frequency of purulent-septic complications;

simplicity in installation and reliability in work;

lack of special energy-intensive equipment.

The use of the proposed dialysis complex allows for effective local detoxification of open and closed infected cavities both in stationary and in extreme conditions of peacetime and war.

Information sources:

1. Gulman M.I., Vinnik Yu.S., Miller S.V. et al. Atlas of drainage in surgery. - Krasnoyarsk, 2004. - P.36-37;

2. Naumov N.V., Shvetsky A.G., Runkelov N.V., Naumova E.B. Semi-permeable membrane in coloproctology. - Krasnoyarsk: Sibmed, 1999 .-- p.90.

3. Gulman M.I., Vinnik Yu.S., Miller S.V. et al. Atlas of drainage in surgery. - Krasnoyarsk, 2004. - P.54-56;

Claims (1)

Flowing transmembrane dialysis complex, which includes a system for introducing a dialysate solution into a membrane capsule installed in an infected cavity, and a spent dialysate removal system, characterized in that the container with the dialysis solution and the container with spent dialysate are interconnected by means of an elastic air duct, as a result of which a vacuum is created in the container for the spent dialysate, which ensures dialysis, while the tube for feeding the dialysate solution and the tube for Oda spent dialysate summed directly to the membrane capsule and fixed on it.