CN211024414U - ECMO closed pre-charging device - Google Patents

Abstract

The utility model relates to the field of medical equipment, a ECMO closed preflush device is disclosed, including ECMO device and with the accurate infusion external member of ECMO device intercommunication, the ECMO device includes ECMO machine, centrifugal pump, membrane lung exit end to the drainage tube of centrifugal pump entry end, centrifugal pump exit end to the drainage tube of membrane lung entry end and two interfaces on the drainage tube of membrane lung exit end to the centrifugal pump entry end, accurate infusion external member includes backward flow bag and preflush bag, and this preflush bag and backward flow bag pass through the passageway intercommunication, and this passageway is equipped with filter head and one-way check valve, and the preflush bag even is equipped with the ECMO preflush pipe of connecting two interfaces respectively with backward flow bag lower part. The utility model discloses a filter head destroys intraductal preflush liquid bubble, and the preflush liquid circulates in advance through one-way check valve after, realizes the pipeline preflush of ECMO device, replaces air and bubble in the pipeline, save time, pollution abatement, and the preflush thoroughly, guarantees that ECMO effectively implements, strives for the time for rescuing the patient.

Description

An ECMO airtight pre-charging device

technical field

The utility model relates to the field of medical instruments, in particular to an ECMO airtight prefilling device.

Background technique

Extracorporeal membrane oxygenation (ECMO) is a technology for rescuing patients with severe heart and lung failure, representing the level of critical illness treatment in a country, region, and hospital. At present, ECMO technology is even considered to redefine the boundary between life and death. ECMO is an extracorporeal circulation technology that goes out of the heart operating room. Its principle is to lead the venous blood from the body out of the body, and then inject it into the patient's arterial or venous system after artificial cardiopulmonary bypass oxygenation with special materials, which plays a role of partial cardiopulmonary replacement and maintains human organs. Tissue oxygenation blood supply.

The basic structure of ECMO includes intravascular cannula, connecting tube, centrifugal pump (artificial heart), oxygenator (artificial lung), oxygen supply tube, and monitoring system. In clinical practice, the disposable parts are often combined into a kit, and the non-disposable parts are bound and stored, and are designed to be movable to improve emergency response capabilities.

The function of membrane lung is to synthesize oxygenated blood from non-oxygenated blood, also known as artificial lung. ECMO oxygenator is available in two types: silica membrane type and hollow fiber type. The silicone membrane type membrane lung has good compatibility, less plasma leakage, and less damage to blood components, so it is suitable for long-term assistance. For example, support cardiopulmonary function waiting for transplantation, respiratory failure caused by infection. The disadvantage is that the exhaust is difficult and expensive. The hollow fiber membrane lung is easy to exhaust, and plasma leakage can be seen within 2-3 days, and the damage to blood components is relatively large, but the first aid kit is still the first choice due to its easy installation. If necessary, a suitable oxygenator can be replaced within one to two days after the condition is stabilized.

The function of the centrifugal pump is to form a power to drive the blood to flow to one side of the pipe, similar to the function of the heart. There are mainly two types of centrifugal pumps in clinical practice: roller pumps and centrifugal pumps. Because the roller pump is not easy to move and difficult to manage, the centrifugal pump is the first choice for the first aid professional as the centrifugal pump. Its advantages are that it is easy to install and move, easy to manage and less blood damage; it has a suction effect within a reasonable negative pressure range, which can solve the problem of low flow caused by some reasons; the new generation of centrifugal pumps is also easy to control for children with low flow.

With the advancement of technology, ECMO is used more and more in critical diseases, but the pipeline must be pre-filled before use. patient life. At the same time, the first pre-charging is not complete, the time-consuming re-pre-charging increases, and the patient's cost increases, which affects the timely and effective application of ECMO.

Utility model content

In order to solve the above problems, the utility model provides an ECMO airtight pre-filling device, which can destroy the air bubbles of the pre-flushing liquid in the pipe through the filter head, and the pre-flushing liquid can circulate the pre-flushing liquid after passing through the filter head and the one-way check valve. Only a small amount of pre-flushing liquid can be used to pre-flush the pipeline of the ECMO device and replace the air and air bubbles in the pipeline.

In order to achieve the above purpose, the ECMO airtight pre-filling device of the present invention is communicated with an ECMO device, and the ECMO device includes an ECMO machine, a centrifugal pump, a membrane lung, and a drainage tube from the outlet end of the membrane lung to the inlet end of the centrifugal pump. The second drainage tube from the pump outlet end to the membrane lung inlet end and the first interface and the second interface on the first drainage tube from the membrane lung outlet end to the centrifugal pump inlet end;

A precision infusion set connected with the ECMO device, the precision infusion set includes a return bag and a pre-flushing bag;

The pre-flushing bag and the return bag are communicated through a channel, the channel is provided with a filter head and a one-way check valve, and the lower part of the pre-flushing bag is provided with an ECMO connecting the outlet end of the membrane lung to the inlet end of the centrifugal pump. Pre-flushing tube 1, the lower part of the return bag is provided with an ECMO pre-flushing tube 2 connecting the outlet end of the membrane lung to the interface 2 on the drainage tube 1 of the inlet end of the centrifugal pump;

The filter head is used to destroy air bubbles in the pre-flush;

a clamp part, the clamp part includes a first blood vessel clamp, a second blood vessel clamp, a third blood vessel clamp and a fourth blood vessel clamp;

The first blood vessel clamp is arranged on the ECMO drainage tube one between the first port and the second port, and after the first blood vessel clamp is clamped, it can prevent the priming fluid flowing out from the outlet end of the membrane lung from returning to the inlet end of the centrifugal pump;

The second blood vessel clamp is arranged on the second drainage tube between the outlet end of the centrifugal pump and the inlet end of the membrane lung, and is used to clamp the pipeline when the ECMO machine starts/stops;

The third blood vessel clamp is arranged on the second ECMO pre-flushing tube at the lower part of the return bag;

The fourth blood vessel clamp is arranged on the ECMO pre-flushing tube 1 at the lower part of the pre-flushing bag, and the third blood vessel clamp and the fourth blood vessel clamp can close/open the flow of the pre-flushing solution.

Preferably, the filter head is located on the channel connecting the return bag and the pre-flushing bag, and is fixedly connected with the one-way check valve.

Preferably, the filter head is a hollow structure composed of an outlet end, an inlet end and a side wall extending therebetween, and the side wall of the filter head is provided with a plurality of filter holes penetrating in the direction of the side wall.

Preferably, the diameter of the filter hole is 0.3-0.6 mm, and the length of the filter hole is 5-8 mm.

Preferably, the filter head is a boss-type hollow structure, the left end of the filter head is an inlet end connected to a return bag, the right end is an outlet end connected to a one-way check valve, and the opening diameter of the inlet end of the filter head is larger than that of the outlet end of the right end. Opening diameter.

Preferably, the one-way check valve is a one-way valve body, and the pre-flushing liquid entering the filter head can only enter the pre-flushing bag through the one-way check valve, and the pre-flushing liquid in the pre-flushing bag cannot directly pass through the one-way check valve. The return valve goes into the return bag.

Preferably, the first interface and the second interface are provided with internal threads, and one end of the second ECMO pre-flushing tube at the lower part of the return bag and one end of the ECMO pre-flushing tube 1 at the lower part of the pre-flushing bag are both provided with external threads;

Preferably, the external thread of the ECMO pre-flushing tube 1 at the lower part of the pre-flushing bag can be connected with the inner thread of the interface 1, and the external thread of the ECMO pre-flushing tube 2 at the lower part of the return bag can be connected with the inner thread of the interface 2.

Preferably, a puncture needle is provided on the other end of the ECMO pre-flushing tube 2 at the lower part of the return bag and the other end of the ECMO pre-flushing tube 1 at the lower part of the pre-flushing bag for connecting the pre-flushing bag and the return bag.

Preferably, the heights of the channel connecting the pre-flushing bag and the return bag, the filter head and the one-way check valve are located on the same horizontal plane and at 1/3 to 1/4 of the height of the pre-flushing bag.

Preferably, the bottom surfaces of the pre-flushing bag and the return bag have the same size, and the volume of the return bag does not exceed half of the volume of the pre-flush bag.

The beneficial effect of the utility model is: using the device of the utility model, the utility model pumps the pre-flushing liquid of the pre-flushing bag to the return bag through the centrifugal pump to form the pre-flushing of the ECMO pipeline, when the pre-flushing liquid in the return bag is used for the pre-flushing When the liquid height exceeds the height of the filter head, the pre-flushing liquid of the return bag enters the pre-flushing bag through the filter head and the one-way check valve, and at the same time, the filter head intercepts and destroys the air bubbles in the pre-flushing liquid, making it difficult for the air bubbles to enter the ECMO pipeline. inside, and the priming fluid can circulate in the pipeline. The whole pre-flushing of the utility model is carried out in a closed environment, eliminating the need for extubation and intubation when replacing the pre-flushing bag in the traditional pre-flushing, and the entire operation process is sterile. Compared with the traditional method, the pre-flushing is more thorough and can save time. , reduce pollution, can ensure the effective implementation of ECMO, improve work efficiency, save time for rescuing patients, and save costs.

Description of drawings

1 is a schematic diagram of an ECMO airtight pre-priming device according to a preferred embodiment of the present invention;

Fig. 2 is the filter head sectional view of the utility model;

3 is a cross-sectional view of a precision infusion kit according to a preferred embodiment of the present invention;

Description of reference numerals

1- Centrifugal pump, 2- Membrane lung, 3- Drainage tube 1, 31-Port 1, 32-Port 2, 4-Drainage tube 2, 5-Pre-flushing bag, 51-ECMO pre-flushing tube 1, 6-Return bag , 61-ECMO pre-flushing pipe two, 7-channel, 71-filter head, 711-outlet end, 712-inlet end, 713-side wall 713, 714-filter hole, 72-one-way check valve, 81-section A vessel clamp, 82-second vessel clamp, 83-third vessel clamp, 81-fourth vessel clamp.

Detailed ways

The present utility model will be described in detail below with reference to the accompanying drawings and specific embodiments. It should be understood that the specific embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

Referring to FIG. 1 , FIG. 2 and FIG. 3 , the present invention provides an ECMO airtight pre-charging device for pre-charging the ECMO device.

The ECMO improved closed pre-filling device of the present invention is communicated with the ECMO device, and the ECMO device comprises an ECMO machine in the prior art, a centrifugal pump 1, a membrane lung 2, and a drainage tube from the outlet end of the membrane lung 2 to the inlet end of the centrifugal pump 1 13. Interface one 31 and interface two 32 on the drainage tube 24 from the outlet end of the centrifugal pump 1 to the inlet end of the membrane lung 2 and the drainage tube 13 from the outlet end of the membrane lung 2 to the inlet end of the centrifugal pump 1;

The ECMO airtight pre-filling device further includes a precision infusion set connected to the ECMO device, and the precision infusion set includes a return bag 6 and a pre-filling bag 5;

The pre-flushing bag 5 and the return bag 6 are communicated through a channel 7, the channel 7 is provided with a filter head 71 and a one-way check valve 72, and the lower part of the pre-flushing bag 5 is provided with a drainage tube connecting the outlet end of the membrane lung 2 to the inlet end of the centrifugal pump 1 ECMO pre-flushing tube 1 51 of interface 31 on 1 3, ECMO pre-flushing tube 2 61 connecting the outlet end of membrane lung 2 to the inlet end of centrifugal pump 1 on drainage tube 1 3 and interface 2 32 on the lower part of return bag 6, The pre-flushing bag 6 is used to provide pre-flushing liquid;

The filter head 71 is used to destroy the air bubbles in the pre-flushing liquid. The filter head 71 is provided with a filter hole 714, and the filter hole 714 communicates with the interior of the filter head 71 and the return bag 6 and the one-way check valve 72. When the filter holes 714 of the filter head 71 are used, air bubbles in the priming solution can be destroyed.

The ECMO airtight pre-filling device of the present invention is further provided with a clamp part, including a first blood vessel clamp 81 , a second blood vessel clamp 82 , a third blood vessel clamp 83 and a fourth blood vessel clamp 84 ;

The first vascular clamp 81 is set on the ECMO drainage tube 1 3 between the port 1 31 and the port 2 32. After the first vascular clamp 81 is clamped, the pre-flush flowing from the outlet end of the membrane lung 2 is prevented from returning to the inlet end of the centrifugal pump 1. .

The second vascular clamp 82 is arranged on the drainage tube 24 from the outlet end of the centrifugal pump 1 to the inlet end of the membrane lung 2, and the second vascular clamp 82 clamps the pipeline of the drainage tube 24 when the ECMO machine is turned on/off;

The third vascular clamp 83 is set on the ECMO pre-flushing tube 2 61 at the lower part of the return bag 6 , and the fourth vascular clamp 84 is set on the ECMO pre-flushing tube 1 51 at the lower part of the pre-flushing bag 5 . Vascular clamp 84 can turn off/on the flow of priming fluid.

When using the utility model to pre-flush the ECMO pipeline, the centrifugal pump 1 works to return the pre-flush in the pre-flush bag 5 to the return bag 6 through the centrifugal pump 1 and the membrane lung 2. When the pre-flush in the return bag 6 When the height of the flushing liquid exceeds the height of the filter head 71, the pre-flushing liquid flows through the filter head 71 and the one-way check valve 72 and enters the pre-flushing bag 5, thereby realizing the cyclic pre-flushing of the ECMO device.

The first vascular forceps 81 is clamped, so that the return bag 6, the pre-flush bag 5 and the channel 8 connecting the pre-flush bag 5 and the return bag 6 become the circulating pre-flush bypass instead of this section of pipeline.

The filter head 71 is a hollow structure composed of an outlet end 711, an inlet end 712 and a side wall 713 extending therebetween. 714 communicates the interior of the filter head 71 with the return bag 6 and the one-way check valve 72 .

The filter head 71 is a hollow structure with a large end and a small boss, the large end is the inlet end 712 of the pre-flushing liquid, and the small end is the outlet end 711 of the pre-flushing liquid; the one-way check valve 72 is a one-way Valve body, the pre-flushing liquid entering the filter head 71 can only enter the pre-flushing bag 5 through the one-way valve 72 , and the pre-flushing liquid in the pre-flushing bag 5 cannot directly enter the return bag 6 through the one-way check valve 72 .

In a preferred embodiment of the present invention, the diameter of the filter hole 714 is 0.3-0.6 mm, and the length of the filter hole 714 is 5-8 mm, which can filter the air bubbles in the pre-flushing solution, so that the air bubbles pass through the filter head 71 rupture.

3, in a preferred embodiment of the present invention, the channel 7, the filter head 71 and the one-way check valve 72 communicating with the pre-flushing bag 5 and the return bag 6 are located on the same level and are located in the pre-flushing bag 5 At 1/4 of the height, when the volume of the pre-flush in the pre-flush bag 5 drops to a height not less than the height of the filter head 71, the height of the pre-flush solution in the return bag 6 has exceeded the height of the filter head 71/or the pre-flush solution has been filled The return bag 6 realizes the circulating pre-flushing of the pre-flushing liquid.

The filter head 71 is a boss-type hollow structure, the left end of the filter head 71 is the inlet end 712 connected to the return bag 6, the right end is the outlet end 711 connected to the one-way check valve 72, and the opening diameter of the inlet end 712 of the left end of the filter head 71 is larger than The diameter of the opening of the outlet end 711 at the right end is designed so that the air bubbles can enter the filter head 71 more quickly, and the air bubbles will be destroyed after passing through the filter hole 714 .

The one-way check valve 72 is a one-way valve body, the pre-flushing liquid entering the filter head 71 can only enter the pre-flushing bag 5 through the one-way check valve 72, and the pre-flushing liquid in the pre-flushing bag 5 cannot directly pass through the one-way check valve 72. The check valve 72 enters the return bag 6 .

In the existing ECMO device, the first interface 31 and the second interface 32 are provided with internal threads. In a preferred embodiment of the present invention, the second ECMO pre-flushing tube 61 at the lower part of the return bag 6 and the lower part of the pre-flushing bag 5 The outlet of the ECMO pre-flushing tube-51 is provided with external threads, and the external thread of the ECMO pre-flushing tube-51 at the lower part of the pre-flushing bag 5 is connected with the inner thread of the interface-31, and the ECMO pre-flushing tube at the bottom of the return bag 6 is connected. The external thread of the second 61 is connected with the internal thread of the interface 2 32, which realizes the rapid connection between the precision infusion kit and the ECMO pipeline.

In a preferred embodiment of the present invention, the other end of the ECMO pre-flushing tube 2 61 at the lower part of the return bag 6 and the other end of the ECMO pre-flushing tube 1 51 at the lower part of the pre-flushing bag 5 are provided with plastic steel needles, which can quickly It is directly inserted into the pre-flushing bag 5 and the return bag 6 to realize the quick connection between the ECMO pre-flushing tube 1 51 and the pre-flushing bag 5 , and the quick connection between the ECMO pre-flushing tube 2 61 and the return bag 6 .

In a preferred embodiment of the present invention, the return bag 6 and the pre-flush bag 5 can be processed into a bottle shape or a bag shape, and the size of the bottom surface of the return bag 6 is the same as that of the pre-flush bag 5; The volume is not more than half of the volume of the pre-flush bag 5, the volume relationship between the pre-flush bag 5 and the return bag 6 is such that the volume of the pre-flush liquid in the pre-flush bag 5 falls not less than the height of the filter head 71, and the pre-flush in the return bag 6 is not smaller than the height of the filter head 71. The flushing height has already exceeded the height of the filter head 71, which can ensure the realization of preflushing circulating and preflushing.

In a preferred embodiment of the present invention, using the ECMO airtight pre-priming device to perform priming includes the following steps:

S1. ECMO pre-flushing materials and ECMO machine preparation to ensure that the ECMO machine is in a complete state;

S2. Configure ECMO pre-flushing solution, and then add the pre-flushing solution to the pre-flushing bag 5 of the precision infusion kit;

S3. Connect the components of the ECMO device and the pre-charging device;

S4. Using the principle of gravity, first remove the air in the drainage pipe-3 pipeline at the inlet end of the centrifugal pump 1 and the air in the pump head of the centrifugal pump 1;

S5, use the centrifugal pump 1 for pre-flushing;

S6. After the pre-flushing is completed, the intubation of the patient is completed, and the ECMO kit is opened to connect with the intubation of the patient.

Step S1 includes preparing the ECMO machine, vascular clamp, couplant, 700-800ml Ringer's solution, precision infusion kit and ECMO kit; instrument confirmation includes connecting the ECMO power supply, connecting the oxygen source and gas source, and checking that the instrument is in a good standby state.

Step S2 includes mixing 700-800ml of Ringer's solution into the pre-flushing bag 5 of the precision infusion set, inserting the puncture needle of ECMO pre-flushing tube 1 51 into the pre-flushing bag 5, and inserting the puncture needle of ECMO pre-flushing tube 2 61 into the pre-flushing bag 5. Connect to the return bag 6, keep the ECMO pre-flushing tube 1 51 and the ECMO pre-flushing tube 2 61 aseptically suspended on the ECMO infusion stand.

Step S3 is the connection between the ECMO device and the pre-flushing device, first open the ECMO package, connect the drainage tube-3 to the inlet end of the centrifugal pump 1, and fix it with a self-locking cable tie, and connect the interface-31 and the ECMO pre-flushing tube-51 threadedly , place membrane lung 2 on the ECMO fixing frame, connect the oxygen source and gas source, open the variable temperature water tank at the same time, add sterile water for injection without exceeding the water level line, set the temperature to 35 ℃ ~ 37 ℃, connect the ECMO machine for oxygenation The pressure extension tubes at both ends of the device, the outlet end of the membrane lung 2 is connected to the other end of the drainage tube 1 3, and the interface 2 32 and the ECMO pre-flushing tube 2 61 are screwed together; A vascular clamp 81 clamps the ECMO drainage tube 1 3 between the first port 31 and the second port 32 , and the clamping position is close to the inlet end of the centrifugal pump 1 .

Step S4 includes S41. Open the third vascular clamp 83 and the fourth vascular clamp 84, the priming fluid flows into the drainage tube-3 pipeline at the inlet end of the centrifugal pump 1 due to its own gravity, and cooperates with the vascular clamp to remove the front-end drainage tube-1 of the centrifugal pump 1. 3 and the air in the ECMO pre-flushing tube-51 at the bottom of the pre-flushing bag 5;

S42. Use the vascular clamp to perform reverse exhaust again to exhaust the air in the centrifugal pump 1, so that before the preflush reaches the membrane lung 2, the second vascular clamp 82 clamps the drainage tube 24 between the centrifugal pump 1 and the membrane lung 2 pipeline;

In this way, in the first priming in step S41, the drainage tube 1 3 is connected with the centrifugal pump 1, and the interface 31 and the ECMO priming tube 1 51 are threadedly connected, and then the fourth vascular clamp 84 is opened, and the front end of the centrifugal pump 1 is caused by the action of gravity. The air in the drainage tube-3 and the ECMO pre-flushing tube-51 at the bottom of the pre-flushing bag 5 is discharged more quickly. When the centrifugal pump 1 is filled with the pre-flushing liquid, the outlet end of the centrifugal pump 1 and the inlet end of the membrane lung 2 pass through. The drainage tube two and 4 are connected, so that the pre-charging time can be shortened.

Step S5 includes S51. After the coupling agent is applied to the 1 end of the centrifugal pump, it is loaded into the centrifugal pump 1 driving device of the ECMO machine;

S52. The instrument is reset to zero: the instrument is turned on for self-checking, the main switch of the instrument is always in the ON state, long press the reset button, and four 0s appear on the screen, that is, the zeroing is successful;

S53. Adjust the rotational speed of centrifugal pump 1 to 1500, open the second blood vessel clamp 82 at the pump head outlet of centrifugal pump 1, and then adjust the rotational speed of centrifugal pump 1 to 2500. Pay attention to the liquid level in the return bag 6 and the pre-flushing bag 5 ; During the pre-filling process, check whether there are air bubbles in each joint, tighten each joint, and remove the air from the pressure extension tubes at both ends and the interface behind the membrane before and above the membrane;

S54. When the height of the pre-flushing liquid in the return bag 6 and the pre-flushing bag 5 is higher than the filter head 71, the ECMO starts to remove the remaining air bubbles in the pipeline from the circulation, and confirms again that there are no air bubbles in the pipeline.

Step S6 includes: S61. Adjust the rotational speed of the centrifugal pump 1 to 1500, use the second vascular clamp 82 to clamp the drainage tube 2 4 at the outlet end of the centrifugal pump 1, immediately adjust the rotational speed to 0, and remove the ECMO pre-flushing tube 2 61 and ECMO pre-flushing tube 1 51, connect the upper heparin cap to interface 1 31 and interface 2 32, then adjust the speed to 1500, release the first vascular clamp 81 and the second vascular clamp 82 at the same time, the instrument starts to circulate;

S62. Set the arterial cannula and venous cannula in place, stop the ECMO machine, open the wrapping tube package, hand the pipeline to the doctor on the table in a sterile environment, straighten out the entire circulation pipeline, and fix it in a proper position.

In the pre-flushing process of the present invention, the air in the ECMO pipeline is replaced by the pre-flushing liquid in the precision infusion kit, and the air bubbles in the pre-flushing liquid are destroyed by the interception of the filter head 71, so that the circulating pre-flushing The liquid does not contain air, and after repeated pre-flushing cycles, the air in the ECMO pipeline can be removed; after the pre-flushing liquid in the pre-flushing bag 5 is pumped into the return bag 6, it is returned to the pre-flushing bag through the channel 7 5, the whole pre-flush can circulate.

The whole pre-flushing of the utility model is carried out in a closed environment, which avoids the problem of incomplete pre-flushing caused by extubation and intubation in the traditional pre-flushing process, and the entire operation process is sterile. Compared with the traditional method, the pre-flushing is more thorough and can save money Time, reduce pollution, and reduce the incidence of complications such as membrane lung coagulation and air embolism, which can ensure the effective implementation of ECMO, improve work efficiency, save time for rescuing patients, and save costs.

The above are the preferred embodiments of the present utility model, explaining the basic structure, operation method and advantages of the present utility model. However, the present utility model is not limited to this. The technical solution of the new model carries out a variety of simple modifications, including combining various technical features in any other suitable manner. These simple modifications and combinations should also be regarded as the contents disclosed in the present invention, and belong to the protection scope of the present invention.

Claims (10)

1. An ECMO pre-fill apparatus, comprising:

the ECMO device comprises an ECMO machine, a centrifugal pump (1), a membrane lung (2), a first drainage tube (3) from the outlet end of the membrane lung (2) to the inlet end of the centrifugal pump (1), a second drainage tube (4) from the outlet end of the centrifugal pump (1) to the inlet end of the membrane lung (2), and a first interface (31) and a second interface (32) on the first drainage tube (3) from the outlet end of the membrane lung (2) to the inlet end of the centrifugal pump (1);

a precision infusion set connected to the ECMO apparatus, the precision infusion set comprising a reflux bag (6) and a priming bag (5);

the pre-flushing bag (5) is communicated with the backflow bag (6) through a channel (7), the channel (7) is provided with a filter head (71) and a one-way check valve (72), the lower part of the pre-flushing bag (5) is provided with a first ECMO pre-flushing pipe (51) which is used for connecting the outlet end of the membrane lung (2) to a first interface (31) on a first drainage pipe (3) at the inlet end of the centrifugal pump (1), and the lower part of the backflow bag (6) is provided with a second ECMO pre-flushing pipe (61) which is used for connecting the outlet end of the membrane lung (2) to a second interface (32) on the first drainage pipe (3) at the inlet end;

the filter head (71) is used for destroying bubbles in the pre-flushing liquid;

a clamp portion comprising a first vascular clamp (81), a second vascular clamp (82), a third vascular clamp (83), and a fourth vascular clamp (84);

the first vascular clamp (81) is arranged on the ECMO drainage tube I (3) between the interface I (31) and the interface II (32), and the pre-flushing liquid flowing out from the outlet end of the membrane lung (2) can be prevented from returning to the inlet end of the centrifugal pump (1) after the first vascular clamp (81) is clamped;

the second vascular clamp (82) is arranged on a second drainage tube (4) from the outlet end of the centrifugal pump (1) to the inlet end of the membrane lung (2) and is used for clamping a pipeline at the position when the ECMO machine is started up/shut down;

the third vascular clamp (83) is arranged on the ECMO pre-flushing pipe II (61) at the lower part of the reflux bag (6);

the fourth vascular clamp (84) is arranged on the first ECMO pre-flushing pipe (51) at the lower part of the pre-flushing bag (5), and the third vascular clamp (83) and the fourth vascular clamp (84) can close/open the flow of the pre-flushing liquid.

2. The ECMO pre-fill system according to claim 1, wherein the filter head (71) is located in a passage (7) communicating the return bag (6) and the pre-fill bag (5), and is fixedly connected to the one-way check valve (72).

3. The ECMO pre-fill system according to claim 2, wherein the filter head (71) is a hollow structure having an outlet end (711), an inlet end (712), and sidewalls (713) extending therebetween, and the sidewalls (713) of the filter head (71) are provided with a plurality of filter holes (714) extending therethrough in a direction of the sidewalls.

4. The ECMO pre-fill system as claimed in claim 3, wherein the diameter of the filtering hole (714) is 0.3-0.6 mm, and the length of the filtering hole (714) is 5-8 mm.

5. An ECMO pre-fill system according to any one of claims 1-4, wherein the filter head (71) is a hollow structure of boss type, the left end of the filter head (71) is connected to the inlet port (712) of the return bag (6), the right end is connected to the outlet port (711) of the return bag (72), and the diameter of the opening of the inlet port (712) at the left end of the filter head (71) is larger than the diameter of the opening of the outlet port (711) at the right end.

6. An ECMO pre-fill device in accordance with any one of claims 1-4, wherein the one-way check valve (72) is a one-way valve body, and pre-fill fluid entering the filter head (71) can only enter the pre-fill bag (5) through the one-way check valve (72), and pre-fill fluid entering the pre-fill bag (5) cannot directly enter the return bag (6) through the one-way check valve (72).

7. An ECMO hermetic pre-filling device according to any one of claims 1-4, wherein the first port (31) and the second port (32) are provided with female screws, and one end of the second ECMO pre-filling pipe (61) at the lower part of the return bag (6) and one end of the first ECMO pre-filling pipe (51) at the lower part of the pre-filling bag (5) are both provided with male screws;

the external thread of an ECMO pre-washing pipe I (51) at the lower part of the pre-washing bag (5) can be connected with the internal thread of the connector I (31), and the external thread of an ECMO pre-washing pipe II (61) at the lower part of the backflow bag (6) can be connected with the internal thread of the connector II (32).

8. An ECMO hermetic pre-filling device according to any one of claims 1-4, wherein the other end of the ECMO pre-filling tube II (61) at the lower part of the pre-filling bag (6) and the other end of the ECMO pre-filling tube I (51) at the lower part of the pre-filling bag (5) are provided with piercing needles for connecting the pre-filling bag (5) and the pre-filling bag (6).

9. An ECMO pre-fill system according to any one of claims 1-4, wherein the height of the passageway (7) connecting the pre-fill bag (5) and the return bag (6), the filter head (71) and the one-way check valve (72) are located on the same horizontal plane and located at 1/3-1/4 of the pre-fill bag (5) height.

10. The ECMO pre-fill system according to claim 8, wherein the pre-fill bag (5) and the return bag (6) have the same size of bottom surface, and the volume of the return bag (6) is not more than half of the volume of the pre-fill bag (5).

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