RU2593953C2 - Вакцины с живыми бактериальными изолятами для системного введения - Google Patents

Вакцины с живыми бактериальными изолятами для системного введения Download PDF

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Publication number
RU2593953C2
RU2593953C2 RU2013133856/10A RU2013133856A RU2593953C2 RU 2593953 C2 RU2593953 C2 RU 2593953C2 RU 2013133856/10 A RU2013133856/10 A RU 2013133856/10A RU 2013133856 A RU2013133856 A RU 2013133856A RU 2593953 C2 RU2593953 C2 RU 2593953C2
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RU
Russia
Prior art keywords
vaccine
bronchiseptica
canine
infection
live
Prior art date
Application number
RU2013133856/10A
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English (en)
Russian (ru)
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RU2013133856A (ru
Inventor
Кевин А. О'КОННЕЛЛ
Ронда ЛАФЛЕР
Гауда Джаяппа ХУЧАППА
Терри Ли УЕСМОЕН
Original Assignee
Интервет Интернэшнл Бв
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Publication of RU2013133856A publication Critical patent/RU2013133856A/ru
Application granted granted Critical
Publication of RU2593953C2 publication Critical patent/RU2593953C2/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18711Rubulavirus, e.g. mumps virus, parainfluenza 2,4
    • C12N2760/18734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2013133856/10A 2010-12-22 2011-12-21 Вакцины с живыми бактериальными изолятами для системного введения RU2593953C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201061425855P 2010-12-22 2010-12-22
US61/425,855 2010-12-22
EP11152829.5 2011-02-01
EP11152829 2011-02-01
US201161556975P 2011-11-08 2011-11-08
US61/556,975 2011-11-08
PCT/IB2011/003100 WO2012085642A1 (en) 2010-12-22 2011-12-21 Vaccines with live bacterial isolates for systemic administration

Publications (2)

Publication Number Publication Date
RU2013133856A RU2013133856A (ru) 2015-01-27
RU2593953C2 true RU2593953C2 (ru) 2016-08-10

Family

ID=43628729

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2013133856/10A RU2593953C2 (ru) 2010-12-22 2011-12-21 Вакцины с живыми бактериальными изолятами для системного введения

Country Status (8)

Country Link
US (1) US8821852B2 (https=)
EP (1) EP2655403A1 (https=)
JP (1) JP6145046B2 (https=)
CN (1) CN103261214B (https=)
BR (1) BR112013015009B1 (https=)
CA (2) CA2821422C (https=)
RU (1) RU2593953C2 (https=)
WO (1) WO2012085642A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729683B (zh) * 2016-12-16 2019-12-03 青岛易邦生物工程有限公司 一种猪支气管败血波氏杆菌病疫苗
JP2022520925A (ja) * 2019-01-04 2022-04-04 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 弱毒化ボルデテラ・ブロンキセプチカ株、当該弱毒化株を含む経口ワクチン並びに前記の製造及び使用方法
EP4061303A1 (en) * 2019-11-18 2022-09-28 Elanco Us Inc. Lyophilized cake in straight-walled vial
MX2022007578A (es) * 2019-12-18 2022-07-19 Intervet Int Bv Vacuna respiratoria oral.
EP3909971A1 (en) 2020-09-28 2021-11-17 Institute of Life Sciences (ILS) Whole cell livestock vaccine for respiratory diseases

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989005856A1 (en) * 1987-12-23 1989-06-29 The Wellcome Foundation Limited Vaccines
WO2003060105A1 (en) * 2001-12-28 2003-07-24 University Of Southern Queensland Defective entities and uses therefor
RU2005124130A (ru) * 2003-01-29 2006-01-20 Пфайзер Продактс Инк. (Us) Вакцины для собак против bordetella bronchiseptica
CN101575586B (zh) * 2009-05-31 2011-01-19 华中农业大学 一种支气管败血波氏杆菌基因缺失疫苗及应用

Family Cites Families (9)

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US5955089A (en) * 1993-04-20 1999-09-21 Uab Research Foundation Strain selection of pneumococcal surface proteins
US5840556A (en) 1996-05-08 1998-11-24 The United States Of America As Represented By The Department Of Agriculture Molecular genetic construction of vaccine strains of pasteurellaceae
EP0835928A1 (en) * 1996-10-11 1998-04-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin Helicobacter pylori live vaccine
US7959929B2 (en) 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
PH12011502633A1 (en) * 2005-10-07 2012-11-12 Zoetis P Llc Vaccines and methods to treat canine influenza
EP3800244A1 (en) 2006-03-10 2021-04-07 Institut Pasteur de Lille Live attenuated bordetella strains as a single dose vaccine against whooping cough
EP2134359A4 (en) 2007-02-23 2010-06-16 Penn State Res Found USE OF A NONVIRULENT BORDETELLA MUTANT AS LIVING VACCINE VECTOR
KR20080082883A (ko) * 2007-03-09 2008-09-12 전남대학교산학협력단 약독화된 보르데텔라 브론키셉티카 (bbs) 균주 및 그의제조 방법, 그를 포함하는 면역원성 조성물 및 그를 이용한포유동물의 bbs 감염증을 치료 또는 예방하는 방법
TWI468157B (zh) 2009-04-29 2015-01-11 Intervet Int Bv 形成錠劑的方法,進行該方法的系統及包含該錠劑的包裝物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989005856A1 (en) * 1987-12-23 1989-06-29 The Wellcome Foundation Limited Vaccines
WO2003060105A1 (en) * 2001-12-28 2003-07-24 University Of Southern Queensland Defective entities and uses therefor
RU2005124130A (ru) * 2003-01-29 2006-01-20 Пфайзер Продактс Инк. (Us) Вакцины для собак против bordetella bronchiseptica
CN101575586B (zh) * 2009-05-31 2011-01-19 华中农业大学 一种支气管败血波氏杆菌基因缺失疫苗及应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHLADEK D.W. ET AL. Canine parainfluenza-Bordetella bronchiseptica vaccine immunogenicity. AMERICAN JOURNAL OF VETERINARY RESEARCH. 1981. Vol. 42. No 2. P. 266-270. *
MCARTHUR J.D. ET AL. An aromatic amino acid auxotrophic mutant of Bordetella bronchiseptica is attenuated and immunogenic in a mouse model of infection. FEMS MICROBIOLOGY LETTERS. 2003. Vol. 221. P. 7-16. *

Also Published As

Publication number Publication date
JP2014500302A (ja) 2014-01-09
US20130273100A1 (en) 2013-10-17
JP6145046B2 (ja) 2017-06-07
EP2655403A1 (en) 2013-10-30
CA2821422A1 (en) 2012-06-28
BR112013015009B1 (pt) 2020-11-10
CA2821422C (en) 2024-01-02
CA3219727A1 (en) 2012-06-28
WO2012085642A1 (en) 2012-06-28
CN103261214B (zh) 2016-10-26
RU2013133856A (ru) 2015-01-27
US8821852B2 (en) 2014-09-02
CN103261214A (zh) 2013-08-21
BR112013015009A2 (pt) 2016-08-09

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