RU2564000C2 - Method for producing anti-inflammatory agent, version 5 - Google Patents

Abstract

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to the pharmaceutical industry, namely to a method for producing an anti-inflammatory agent. The method for producing the anti-inflammatory agent from an elevated part of Geranium eriostemon Fisch., which is dried, milled, extracted in 60% ethanol in a porcelain dish while stirring, filtered through a paper filter; the filtrate is evaporated in a porcelain dish to a dry residue in a certain environment.

EFFECT: agent produced by the method described above possesses an evident anti-inflammatory action.

Description

FIELD OF THE INVENTION

The invention relates to medicine, namely to pharmacology. The proposed product can be used as an anti-inflammatory agent.

State of the art

An analogue of the claimed product is a herbal product (RU 94025157 A1), which relates to compositions based on plant materials, and is a substance for dosage forms of anti-inflammatory and wound healing effects for external use in paraproctitis, ulcerative processes with infiltration and atrophic ulcers, as well as for internal use for injuries, fractures and to normalize the intestinal biocenosis in drug dysbacterioses. In addition, the composition can be used as a stimulant for the growth of plants, farm animals and poultry, as a biologically active substance for the manufacture of artificial soil, for the preparation (cultivation) of mycelial masses and fruit bodies of mushrooms, as a component of a cutting fluid, as a food additive, as a compound component in the perfumery and cosmetic industries, etc.

An object of the invention is the expansion of the raw material base (feedstock) for preparing the composition, its artificial production with adjustable properties.

The prototype is a plant-based agent (RU 2116079 C1) based on biologically active substances of plant origin, which can be used as an anti-inflammatory, immunomodulatory, anabolic agent. This phytopreparation of biogenic action contains alfalfa extract (50-90 wt.%) And fillers, as fillers - calcium gluconate, sucrose, calcium stearate and talc (9.6-53.0 wt.%). The invention provides an extension of the scope of the drug due to the absence of contraindications and side effects.

Disclosure of invention

The objective of the invention is to expand the range of anti-inflammatory drugs obtained in the form of a dry extract from plant materials.

The proposed product is obtained from Geranium eriostemon Fisch. - Hairy geranium.

To obtain the proposed product, the aerial part of the specified plant is taken, dried, crushed to a particle size of 2-3 mm, extraction is carried out for 30-35 minutes with a 60% solution of ethyl alcohol in a mass ratio of 1:20 in porcelain with stirring, filtered through a paper filter, the filtrate is evaporated in porcelain at atmospheric pressure and a temperature of 55-60 ° C to a dry residue.

for example

100 g of dried and crushed plants are hung, placed in porcelain dishes, filled with an aqueous solution of ethyl alcohol (60%) in an amount of 2000 g, incubated for 30-35 minutes, filtered through a paper filter, evaporated to a dry residue, and the dry residue is stored in a protected away from light at a temperature of 18-20 ° C for no more than 2 years.

The effect of the proposed tool on laboratory animals was investigated. At the same time, a statistically significant improvement in their condition was recorded, not inferior to the comparison drugs.

Claims (1)

The method of obtaining anti-inflammatory drugs from plant materials, which consists in the fact that they take the aerial part of Geranium eriostemon Fisch. (Hairy geranium), dried, crushed to a particle size of 2-3 mm, extraction is carried out for 30-35 minutes with a 60% solution of ethyl alcohol in a mass ratio of 1:20 in a porcelain dish with stirring, filtered through a paper filter, the filtrate is evaporated in porcelain dishes at atmospheric pressure and a temperature of 55-60 ° C to a dry residue.