RU2524188C1 - Rodenticide composition "izorat-3" (versions) - Google Patents

Abstract

FIELD: agriculture.

SUBSTANCE: rodenticide composition comprises anticoagulant - zoocumarin, gelling agent - xanthan or carrageenan, or a mixture of xanthan and locust gum, or a mixture of carrageenan and locust gum, or a mixture of xanthan and guar gum, dye and water. It additionally comprises sulphaquinoxaline, polyethylene glycol as a stabiliser. The rodenticide composition comprises carmine or carmoisine as dye, or chlorophyll, or methylene blue. Also the rodenticide composition may additionally comprise a preservative-potassium sorbate or sodium benzoate. Also the rodenticide composition additionally comprises an attractant, and as the attractant it may comprise sugar or honey, or vegetable oil - sunflower or corn, or wheat or barley grain, or seeds of sunflowers.

EFFECT: rodenticide composition is effective in destruction of rats and rodents, including those resistant to first generation anticoagulants, retains its shape and stability of the freeze-thaw cycle and is suitable for use at any time of the year, including in sub-zero temperatures.

24 cl, 106 ex

Description

The invention relates to agriculture and can be used to exterminate rats and mice.

Known rodenticidal composition, including the active substance - anticoagulant, attractant and food base, and zoocoumarin (2α-phenyl-β-acetyl ethyl) -4-hydroxycoumarin is used as an anticoagulant. C ₁₉ H ₁₆ O ₄ (TU9392-042-0049413-02. Guidelines for the use of zoocoumarin dust for rodent control in veterinary services ”, approved by the Department of Veterinary of the Ministry of Agriculture of the Russian Federation on September 18, 1995, No. 13-7-2 / 395).

However, the known composition is not effective enough, it must be reused (at least 3-4-fold use). In addition, with prolonged use in a number of populations of rodents (especially rats), resistance to this rodenticide appears, as a result of which its activity sharply decreases.

Known rodenticidal composition in polyethylene glycol, including the active substance - the first generation anticoagulant - zoocoumarin with the addition of sulfachinoxaline - synergist to it (patent RU 2285404 C2, IPC A01N 25/08, publ. 20.10.2006, Bull. No. 29). However, the known composition is not effective enough due to the low rodent eatability of grain-based baits.

Also known rodenticidal composition, including the active substance - anticoagulant, gelling agent - xanthan or carrageenan, stabilizer, dye and water (patent RU 2324349, IPC A01N 25/04, publ. 05.20.2008, BI No. 14). In the known composition, anticoagulants of intestinal action, anticoagulants (anticoagulants) from the group of derivatives of indandion or hydroxycoumarin (1st and 2nd generation), in particular (1-phenyl-2-acetyl) -3-ethyl-4, are used as an anticoagulant -hydroxycoumarin ("warfarin"), 3- (α-acetonyl-4-chloro-benzyl) -4-hydroxycoumarin ("coumachlor"), [3- (4'-hydroxy-3'-coumarin) -3-phenyl- 1- (4'-bromo-4'-biphenyl) -propan-1-ol ("bromadiolone"), 3- (3'-paradiphenylyl-1 ', 2', 3 ', 4'-tetrahydro-1'- naphthyl) -4-hydroxycoumarin ("diphenacum"), brodifacum, flocumafen and 3- (1 ', 2', 3 ', 4'-tetrahydro-1'-naphthyl) -4- idroksikumarin ( "kumatetralil"); derivatives of indandion, in particular 1,1-diphenyl-2-acetylindane-1,3-dione ("difacinone") and (1'-p-chlorophenyl-1'-phenyl) -2-acetylindane-1,3-dione ( “chlordifacinone”), as well as hydroxy-4-benzothiopyranones, for example, “diphethalion” As other anticoagulants suitable for preparing the bait according to the invention, mention should be made of benzhydryl ketones and benzhydryl carbinols substituted by 2-azacycloalkylmethyl: 1-phenyl-3- (2-piperidyl) -1- (p-tolyl) -2-propanone, 3.3- diphenyl-1- (2-pyrrolidinyl) -2-pentanone, 1,1-diphenyl-3- [2- (hexahydro-1H-azepinyl)] - 2-propanone, 1- (4-fluorophenyl) -1-phenyl- 3- (2-piperidyl) -2-propanone, 1- (4-methylthiophenyl) -1-phenyl-3- (5,5-dimethyl-2-pyrrolidinyl) -2-propanone, 1- (p-cumenyl) - 1-phenyl-3- (4-tert-butyl-2-piperidinyl) -2-propanone, 3,3-diphenyl-1- [2- (hexahydro-1H-azepinyl] -2-butanone, 3- (2, 4-dichlorophenyl) -3- phenyl-1- (2-piperidyl) 2-heptanone, 1,1-diphenyl-3- (5-methyl-2-pyrrolidinyl) -2-propanone, 3,3-diphenyl-1- (2-piperidyl) -2-butanone, α- (α-methyl-α-phenylbenzyl) -2-piperidinethanol, α- (α-ethyl-α-phenylbenzyl) -2-pyrrolidinethanol, (2,5-dimethyl-α-phenylbenzyl) -2 -piperidinethanol, α- (diphenylmethyl) -2- (hexahydro-1H-azepine) ethanol and the corresponding salts described in German patent application DT-OS 2417783, as well as 4 '- (fluorophenyl) -2- (2-pyrrolidinyl) acetophenone, 4'-phenyl-2- (5,5-dimethyl-2-pyrrolidinyl) acetophenone, 4'- [p- (trifluoromethyl) phenyl] -2- (2-piperidyl) acetophenone, 4 '- (p-butoxyphenyl ) -2- (4-tert-butyl-2-piperidyl) acetophenone, 2'-phenoxy-2- (2-piperidyl) acetophenone, 4 '- (p-fluorophenoxy) -2- (5,5-dimethyl-2-pyrrolidinyl) acetophenone, 4' - (p-chlorophenoxy) -2 - (2-piperidyl) acetophenone, 4 '- [m- (trifluoromethyl) phenoxy] -2- (2-piperidyl) acetophenone, 4' - (p-butoxyphenoxy) -2- (2-pyrrolidinyl) acetophenone, 2- (2-piperidyl) -4 '- (trans-p-tolylvinyl) acetophenone, 2- (2-hexahydro-1H-azepinyl) -4' - (trans-styryl) acetophenone, 4 '- (m-methoxyphenylvinyl) -2 - (2-pyrrolidinyl) acetophenone, 2- (2-piperidyl) -4 '- [(p-methylthio) phenylvinyl] acetophenone, 4' - (3-phenoxypropoxy) -2- (2-piperidyl) acetophenone, 4'- (4-phenylbutyl) -2- (2-piperidyl) acetophenone, 4 '- (α, (-dimethylbenzyl) -2- (piperidyl) acetophenone, 4'-phenylethyl-2- (3,5-diethyl-2-piperidyl) acetophenone, α- [2- (2-phenylethoxy) phenyl] -2-piperidinethanol, α - (p-phenoxyphenyl) -2-pyrrolidinethanol, α- [4- (4-bromophenoxy) phenyl] -6-methyl-2-piperidine-ethanol, α- (p-phenethyl) phenyl-2-pyrpolidinethanol, α-p -bisphenyl-2-hexanehydro-1H-azepinethanol, α- [3- (4-phenoxybutoxy) phenyl] -2-piperidinethanol, α- (4-benzyl) phenyl-2-piperidinethanol and the corresponding salts.

In addition, the following rare-earth metal salts are used as anticoagulants: dineodimide dihydroxybenzene disulfonate, dineodim-3-sulfonate pyridine carboxylate- (4) and germanium- (III) -tris- (4-aminobenzenesulfonate). In addition, any other rodenticidal active agents, in particular acute rodenticides, for example alpha-chloralose, alpha-naphthylthiourea, N-methyl-2,4-dinitro-ro-N- (2,4,6- tribromophenyl) -6- (trifluoromethyl) benzamine ("brometaline"), vitamins D2 and D3 (calciferol, cholecalceferol), (2-chloro-4-dimethyl-amino-6-methylpyrimidine ("crimidine"), O, O-bis (p-chlorophenyl) acetimidoylphosphoramidothioate, sodium monofluoracetate, N-3-pyridylmethyl-N'-p-nitrophenylurea ("pyriminyl"), 3,4,5, -trimethoxybenzoylmethylreserpate ("reserpine"), sulfate t allia, zincfossrid.

Hydroxycoumarins, indandione derivatives and calciferol (vitamins D2 and D3), as well as a combination of anticoagulant with calciferol, are also used as active substances.

As preservatives, the composition contains, for example, paraben (methyl 4-hydroxybenzoate, propyl 4-hydroxybenzoate), benzoic acid and its salts (e.g. sodium benzoate), sorbic acid and its salts (e.g. potassium sorbate), propionic acid and salts thereof (e.g. sodium propionate), ethanol, benzyl alcohol, cresol, chlorocresol, mixtures of chloromethylisothiazolinone and methylisothiazolinone, 2-bromo-2-nitropropane-1,3-diol and 1,2-benzisothiazole-3 (2H) -one .

As moisture stabilizers are used, for example, polyols, in particular glycerol, propylene glycol, ethylene glycol, polyhydric alcohols, which give monosaccharide during oxidation, and polypropylene glycols.

As oxidation stabilizers, bottled oxytoluene, butylated hydroxyanisole, tocopherols (e.g., vitamin E) or ascorbic acid and its derivatives (e.g., ascorbic acid palmitate, sodium ascorbate) are used.

As dyes, blue, green and red pigment dyes are used, as well as blue, green and red soluble dyes.

Vegetable or animal foods or feeds are used as bait materials: cereal or flour meal (for example, from oats, wheat, barley, corn, soybeans, rice), coconut flakes and flour, sugar syrups (for example, glucose syrup obtained by hydrolysis of starch, invert sugar syrup, beet sugar, maple syrup), sugar (e.g. sucrose, lactose, fructose, glucose), scrapers and flour of nuts (e.g. hazelnuts and walnuts, almonds), vegetable fats / oils (e.g. rapeseed, soy, sunflower, cocoa, peanut, corn oils), animal fats / oils (e.g. butter, melted pork fat, fish oil), proteins (e.g. skimmed milk powder, egg powder, protein hydrolysates).

However, the known rodenticidal compositions are not effective enough at sub-zero temperatures - their attractiveness for rodents and, accordingly, rodenticidal activity are reduced. In the study of the stability of the compositions in the freeze-thaw cycles, it was observed that a number of reference samples are characterized by synerisation - the removal of moisture from the gel.

The objective of the invention is to create a finished gel-like bait, effective in the fight against rodents at any time of the year, including at subzero temperatures.

A group of inventions is proposed, combined by a single inventive concept with the achievement of a single technical result.

The problem is solved in a rodenticidal composition, including the active substance - an anticoagulant, a gelling agent, a dye and water, by the fact that it contains zoocoumarin as an anticoagulant, additionally contains xanthan or carrageenan, or a mixture of xanthan and carob gum taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture of carrageenan and locust bean gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture of xanthan and guar gum they are found in a weight ratio equal to (1-9) :( 1-9), respectively, additionally contains sulfachinoxaline in the following ratio of components, wt.%:

Zoocoumarin 0.01-5.0 Sulfachinoxaline 0.025-0.1 Xanthan, or carrageenan, or a mixture of xanthan and carob gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture of carrageenan and carob gum, taken in a weight ratio equal to (1- 9) :( 1-9), respectively, or a mixture of xanthan gum and guar gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively 0.3-15 Dye 0.02-0.05 Water, or milk, or whey Rest

The problem is also solved in a rodenticidal composition, including the active substance - anticoagulant, gelling agent, stabilizer, dye and water, in that it contains zoocoumarin as an anticoagulant, additionally contains xanthan or carrageenan, or a mixture of xanthan and carob gum as a gelling substance taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture of carrageenan and locust bean gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively, or xanthan mixture guar gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively, as a stabilizer - polyethylene glycol sulfahinoksalin further comprises the following component ratio, wt.%:

Zoocoumarin 0.01-5.0 Sulfachinoxaline 0.025-0.1 Xanthan, or carrageenan, or a mixture of xanthan and carob gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture of carrageenan and carob gum, taken in a weight ratio equal to (1- 9) :( 1-9), respectively, or a mixture of xanthan gum and guar gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively 0.3-15 Polyethylene glycol 3.0-20.0 Dye 0.02-0.05 Water, or milk, or whey Rest

The problem is also solved in a rodenticidal composition, including the active substance - anticoagulant, gelling agent, dye and water, in that it contains zoocoumarin as an anticoagulant, additionally contains locust bean gum, or guar gum, and additionally contains sulfachinoxaline in the following ratio components, wt.%:

Zoocoumarin 0.01-5.0 Sulfachinoxaline 0.025-0.1 Locust bean gum or guar gum 4.0-15 Dye 0.02-0.05 Water, or milk, or whey Rest

The problem is also solved in a rodenticidal composition, including the active substance - an anticoagulant, gelling agent, stabilizer, dye and water, in that it contains zoocoumarin as an anticoagulant, additionally contains locust bean gum, or guar gum, as a stabilizer - polyethylene glycol additionally contains sulfachinoxaline in the following ratio of components, wt.%:

Zoocoumarin 0.01-5.0 Sulfachinoxaline 0.025-0.1 Locust bean gum or guar gum 4.0-15 Dye 0.02-0.05 Polyethylene glycol 3.0-20.0 Water, or milk, or whey Rest

The problem is also solved in a rodenticidal composition by the fact that it contains carmine as a dye.

The problem is also solved in a rodenticidal composition by the fact that it additionally contains a preservative - potassium sorbate or sodium benzoate - in a final concentration of 0.01-2.0%.

The task is also solved in a rodenticidal composition by the fact that it additionally contains an attractant.

The task is also solved in a rodenticidal composition by the fact that as an attractant it contains sugar, or honey, or vegetable oil - sunflower, or corn oil - in a final concentration of 1-20%.

The problem is also solved in a rodenticidal composition by the fact that as an attractant contains grain - wheat, or barley, or sunflower seeds - in a final concentration of 10-80%.

Xanthan gum (E415) - corn sugar gum - heteropolysaccharides formed as secondary metabolites during aerobic fermentation of sugars (e.g. corn syrup) by Xanthomonas campestris bacteria, with a molecular weight of one to several millions, the molecules of which are formed from three types of monosaccharides - β, D -glucose, α, D-mannose and α, D-glucuronic acid in a ratio of 2: 2: 1. Xanthan gums are used in food systems as thickeners, gelling agents and stabilizers. Carrageenans (E407) combine a family of polysaccharides contained in red algae. By their chemical nature, they are unbranched sulfated heteroglycans whose molecules are constructed from residues of D-galactopyranose derivatives with a strict alternation of α (1 → 3) and β- (1 → 4) bonds between them, i.e. from repeating disaccharide units, including β-, D-galactopyranose and 3,6-anhydro-α-, D-galactopyranose residues (A.P. Nechaev, A.A. Kochetkova, A.N. Zaitsev “Nutritional Supplements”, M : published by Kolos, 2001, p. 74, 80, 81).

Carob gums (E410) and guar gum (E412) are heteroglycans contained in the seeds of leguminous plants. These gums have a similar chemical structure and are neutral polysaccharides consisting of 1.4 β-glycosidically linked mannose residues, to which side chains consisting of single α, D-galactose residues are attached at equal intervals by 1,6-bonds. For guar gum, called guaran, the galactose residue is attached to every second mannose residue, and for every carob bean gum, to every fourth. Moreover, the galactopyranose structural units are distributed along the polymer chain of mannan not uniformly, but in the form of blocks, which is especially typical for carob tree galactomania. Thus, the polymer chain of gallactomania has an irregular structure with alternating linear and branched zones. The main properties of galactomanians depend on the nature of the distribution of these zones, as well as on the ratio of galactose and mannose. In the food industry, carob gum and guaran are used in the production of dairy products, sauces, flour products, in the production of ice cream, cheeses (A.P. Nechaev, A.A. Kochetkova, A.N. Zaitsev "Food additives", M: ed Kolos, 2001, p. 67-68).

The substance sulfaquinoxaline - C ₁₄ H ₁₂ N ₄ O ₂ S - is a powder of light yellow color, odorless, readily soluble in water and slightly soluble in alcohols, belongs to the group of sulfanilamide preparations. In veterinary practice it is used as a medicinal substance for the treatment of coccidiosis in animals (Yu.V. Borisovich, L.V. Kirillov. “Veterinary preparations”, published by Kolos, 1981, p. 343). However, the known composition is not a bait, but a concentrate, and is an intermediate product for the manufacture of finished baits.

In the patent and scientific and technical literature unknown technical solutions similar to the claimed, i.e. the proposal meets the criteria of the invention of "novelty."

All components of the claimed bait are produced by domestic industry, i.e. the proposal is “industrially applicable”.

We have shown for the first time that the combined use of the above components with rodenticide and synergist allows us to make the finished form of gel-like baits that are attractive to rodents, retain their shape, are stable in the “freeze-thaw” cycle, can stick to surfaces, are effective in exterminating rats and mice, including those resistant to first-generation anticoagulants, therefore, the invention meets the criterion of "inventive step".

The gel according to the invention can also be used as a poisonous coating, or for coating, or for plugging rodent holes. The invention is illustrated by the following examples:

Example 1. 0.01 kg of zookoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine and milk up to 100 kg are mixed, obtaining composition 1 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Xanthan 0.3 Dye 0.02 Milk rest

Example 2. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of xanthan, 0.05 kg of carmine and milk up to 100 kg, obtaining composition 2 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Xanthan 15.0 Dye 0.05 Milk Rest

Example 3. Mix 0.01 kg of zookoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carrageenan and milk up to 100 kg, obtaining a composition of 3 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carrageenan 0.3 Dye 0.02 Milk Rest

Example 4. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of carrageenan, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 4 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Carrageenan 15.0 Dye 0.05 Milk Rest

Example 5. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and locust bean gum in a ratio of 1: 9, 0.02 kg of carmine and milk up to 100 kg, obtaining a composition of 5 in the following ratio, wt. .%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan gum and carob in a ratio of 1: 9 0.3 Dye 0.02 Milk Rest

Example 6. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and locust bean gum in a ratio of 9: 1, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 6 in the following ratio of components, wt .%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and carob in a ratio of 9: 1 15.0 Dye 0.05 Milk Rest

Example 7. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of carrageenan and locust bean gum in a ratio of 1: 9, 0.02 kg of carrageenan and milk up to 100 kg, obtaining a composition of 7 in the following ratio of components, wt .%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of carrageenan and carob gum in a ratio of 9: 1 0.3 Dye 0.02 Milk Rest

Example 8. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of carrageenan and carob gum in a ratio of 9: 1, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 8 in the following ratio of components, wt .%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of carrageenan and carob gum in a ratio of 9: 1 15.0 Dye 0.05 Milk Rest

Example 9. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and guar gum in a ratio of 1: 9, 0.02 kg of carrageenan and milk up to 100 kg, obtaining a composition of 9 in the following ratio, wt. %:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan and guar gum in a ratio of 1: 9 0.3 Dye 0.02 Milk Rest

Example 10. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and guar gum in a ratio of 9: 1, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 10 in the following ratio, wt. %:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and guar gum in a ratio of 9: 1 15.0 Dye 0.05 Milk Rest

Example 11. Mix 0.01 kg of zookoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan gum, 0.02 kg of carmine and water up to 100 kg, obtaining a composition of 11 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Xanthan 0.3 Dye 0.02 Water Rest

Example 12. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of xanthan gum, 0.05 kg of carmine and water up to 100 kg, obtaining a composition of 12 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Xanthan 15.0 Dye 0.05 Water Rest

Example 13. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan gum, 0.02 kg of carrageenan and water to 100 kg, obtaining a composition of 13 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carrageenan 0.3 Dye 0.02 Water Rest

Example 14. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of carrageenan, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 14 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Carrageenan 15.0 Dye 0.05 Water Rest

Example 15. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and locust bean gum in a ratio of 1: 9, 0.02 kg of carmine and water to 100 kg, obtaining a composition of 15 in the following ratio, wt. .%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan gum and carob in a ratio of 1: 9 0.3 Dye 0.02 Water Rest

Example 16. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and locust bean gum in a ratio of 9: 1, 0.05 kg of carmine and water to 100 kg, obtaining a composition of 16 in the following ratio of components, wt .%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and carob in a ratio of 9: 1 15.0 Dye 0.05 Water Rest

Example 17. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of carrageenan and locust bean gum in a ratio of 1: 9, 0.02 kg of carrageenan and water to 100 kg, obtaining a composition of 17 in the following ratio of components, wt .%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of carrageenan and carob gum in a ratio of 9: 1 0.3 Dye 0.02 Water Rest

Example 18. 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of carrageenan and locust bean gum are mixed in a ratio of 9: 1, 0.05 kg of carmine and water to 100 kg, obtaining a composition of 18 in the following ratio of components, wt .%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of carrageenan and carob gum in a ratio of 9: 1 15.0 Dye 0.05 Water Rest

Example 19. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and guar gum in a ratio of 1: 9, 0.02 kg of carrageenan and water to 100 kg, obtaining a composition of 19 in the following ratio of components, wt. %:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan and guar gum in a ratio of 1: 9 0.3 Dye 0.02 Water Rest

Example 20. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and guar gum in a ratio of 9: 1, 0.05 kg of carmine and water to 100 kg, obtaining a composition of 20 in the following ratio, wt. %:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and guar gum in a ratio of 9: 1 15.0 Dye 0.05 Water Rest

Example 21. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine and whey to 100 kg, obtaining a composition of 21 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Xanthan 0.3 Dye 0.02 Milk serum Rest

Example 22. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of xanthan, 0.05 kg of carmine and whey up to 100 kg, obtaining a composition of 22 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Xanthan 15.0 Dye 0.05 Milk serum Rest

Example 23. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carrageenan and whey up to 100 kg, obtaining a composition of 23 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carrageenan 0.3 Dye 0.02 Milk serum Rest

Example 24. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of carrageenan, 0.05 kg of carmine and whey to 100 kg, obtaining a composition of 24 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Carrageenan 15.0 Dye 0.05 Milk serum Rest

Example 25. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and locust bean gum in a ratio of 1: 9, 0.02 kg of carmine and whey up to 100 kg, obtaining a composition of 25 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan gum and carob in a ratio of 1: 9 0.3 Dye 0.02 Milk serum Rest

Example 26. Mix 5.0 kg of zookoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and locust bean gum in a ratio of 9: 1, 0.05 kg of carmine and whey to 100 kg, obtaining a composition of 26 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and carob in a ratio of 9: 1 15.0 Dye 0.05 Milk serum Rest

Example 27. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of carrageenan and locust bean gum in a ratio of 1: 9, 0.02 kg of carrageenan and whey up to 100 kg, obtaining a composition of 27 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of carrageenan and carob gum in a ratio of 9: 1 0.3 Dye 0.02 Milk serum Rest

Example 28. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of carrageenan and locust bean gum in a ratio of 9: 1, 0.05 kg of carmine and whey to 100 kg, obtaining a composition of 28 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of carrageenan and carob gum in a ratio of 9: 1 15.0 Dye 0.05 Milk serum Rest

Example 29. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and guar gum in a ratio of 1: 9, 0.02 kg of carrageenan and whey up to 100 kg, obtaining a composition of 29 in the following ratio, wt. .%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan and guar gum in a ratio of 1: 9 0.3 Dye 0.02 Milk serum Rest

Example 30. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and guar gum in a ratio of 9: 1, 0.05 kg of carmine and whey up to 100 kg, obtaining a composition of 30 in the following ratio of components, wt .%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and guar gum in a ratio of 9: 1 15.0 Dye 0.05 Milk serum Rest

Example 31. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 3.0 kg of polyethylene glycol, 0.3 kg of xanthan, 0.02 kg of carmine and milk up to 100 kg, obtaining a composition of 31 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Xanthan 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk Rest

Example 32. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 20.0 kg of polyethylene glycol, 15 kg of xanthan, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 32 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Xanthan 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk Rest

Example 33. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 3.0 kg of polyethylene glycol, 0.02 kg of carrageenan and milk up to 100 kg, obtaining a composition of 33 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carrageenan 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk Rest

Example 34. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of carrageenan, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 34 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Carrageenan 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk Rest

Example 35. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and locust bean gum in a ratio of 1: 9, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and milk up to 100 kg, obtaining a composition of 35 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan gum and carob in a ratio of 1: 9 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk Rest

Example 36. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and locust bean gum in a ratio of 9: 1, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and milk to 100 kg, obtaining a composition of 36 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and carob in a ratio of 9: 1 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk Rest

Example 37. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of carrageenan and locust bean gum in a ratio of 1: 9, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and milk up to 100 kg, obtaining a composition of 37 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of carrageenan and carob gum in a ratio of 9: 1 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk Rest

Example 38. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of carrageenan and locust bean gum in a ratio of 9: 1, 0.05 kg of carmine, 20.0 kg of polyethylene glycol and milk up to 100 kg, obtaining a composition of 38 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of carrageenan and carob gum in the ratio 15.0 9: 1 Polyethylene glycol 20,0 Dye 0.05 Milk Rest

Example 39. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and guar gum in a ratio of 1: 9, 3.0 kg of polyethylene glycol, 0.02 kg of carrageenan and milk up to 100 kg, obtaining a composition of 39 with the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan and guar gum in a ratio of 1: 9 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk Rest

Example 40. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and guar gum in a ratio of 9: 1, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 40 at the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and guar gum in a ratio of 9: 1 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk Rest

Example 41. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and water up to 100 kg, obtaining composition 41 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Xanthan 0.3 Polyethylene glycol 3.0 Dye 0.02 Water Rest

Example 42. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of xanthan gum, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and water to 100 kg, obtaining a composition of 42 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Xanthan 15.0 Polyethylene glycol 20,0 Dye 0.05 Water Rest

Example 43. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 3.0 kg of polyethylene glycol, 0.02 kg of carrageenan and water up to 100 kg, obtaining a composition of 43 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carrageenan 0.3 Polyethylene glycol 3.0 Dye 0.02 Water Rest

Example 44. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of carrageenan, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 44 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Carrageenan 15.0 Polyethylene glycol 20,0 Dye 0.05 Water Rest

Example 45. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and locust bean gum in a ratio of 1: 9, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and water to 100 kg, obtaining a composition of 45 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan gum and carob in a ratio of 1: 9 0.3 Polyethylene glycol 3.0 Dye 0.02 Water Rest

Example 46. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and locust bean gum in a ratio of 9: 1, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and water to 100 kg, obtaining a composition of 46 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and carob in a ratio of 9: 1 15.0 Polyethylene glycol 20,0 Dye 0.05 Water Rest

Example 47. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of carrageenan and locust bean gum are mixed in a ratio of 1: 9, 0.02 kg of carmine, 3.0 kg of polyethylene glycol and water up to 100 kg, obtaining a composition of 47 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of carrageenan and carob gum in a ratio of 9: 1 0.3 Polyethylene glycol 3.0 Dye 0.02 Water Rest

Example 48. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of carrageenan and locust bean gum in a ratio of 9: 1, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and water to 100 kg, obtaining a composition of 48 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of carrageenan and carob gum in a ratio of 9: 1 15.0 Polyethylene glycol 20,0 Dye 0.05 Water Rest

Example 49. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and guar gum in a ratio of 1: 9, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and water to 100 kg, obtaining a composition of 49 at the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan and guar gum in a ratio of 1: 9 0.3 Dye 0.02 Polyethylene glycol 3.0 Water Rest

Example 50. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and guar gum in a ratio of 9: 1, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and water to 100 kg, obtaining a composition of 50 at the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and guar gum in a ratio of 9: 1 15.0 Polyethylene glycol 20,0 Dye 0.05 Water Rest

Example 51. 0.01 kg of zookoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and whey up to 100 kg are mixed, obtaining composition 51 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Xanthan 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk serum Rest

Example 52. Mix 5.0 kg of zookoumarin, 0.1 kg of sulfachinoxaline, 15 kg of xanthan, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and whey up to 100 kg, obtaining a composition of 52 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Xanthan 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk serum Rest

Example 53. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and whey up to 100 kg, obtaining a composition of 53 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carrageenan 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk serum Rest

Example 54. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of carrageenan, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and whey up to 100 kg, obtaining a composition of 54 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Carrageenan 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk serum Rest

Example 55. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and locust bean gum in a ratio of 1: 9, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and whey up to 100 kg, obtaining the composition 55 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan gum and carob in a ratio of 1: 9 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk serum Rest

Example 56. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and locust bean gum in a ratio of 9: 1, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and whey up to 100 kg, obtaining the composition 56 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and carob in a ratio of 9: 1 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk serum Rest

Example 57. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of carrageenan and locust bean gum in a ratio of 1: 9, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and whey up to 100 kg, obtaining the composition 57 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of carrageenan and carob gum in a ratio of 9: 1 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk serum Rest

Example 58. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of carrageenan and locust bean gum in a ratio of 9: 1, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and whey up to 100 kg, obtaining the composition 58 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of carrageenan and carob gum in a ratio of 9: 1 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk serum Rest

Example 59. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of a mixture of xanthan gum and guar gum in a ratio of 1: 9, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and whey up to 100 kg, obtaining a composition of 59 in the following ratio of components, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 A mixture of xanthan and guar gum in a ratio of 1: 9 0.3 Polyethylene glycol 3.0 Dye 0.02 Milk serum Rest

Example 60. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of a mixture of xanthan gum and guar gum in a ratio of 9: 1, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and whey up to 100 kg, obtaining a composition of 60 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 A mixture of xanthan gum and guar gum in a ratio of 9: 1 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk serum Rest

Example 61. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 4.0 kg of locust bean gum, 0.02 kg of carmine and milk up to 100 kg, obtaining a composition of 61 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carob Gum 4.0 Dye 0.02 Milk Rest

Example 62. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15.0 kg of locust bean gum, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 62 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Carob Gum 15.0 Dye 0.05 Milk Rest

Example 63. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 4.0 kg of guar gum and milk up to 100 kg, obtaining a composition of 63 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Guar gum 4.0 Dye 0.02 Milk Rest

Example 64. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of guar gum, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 64 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Guar gum 15.0 Dye 0.05 Milk Rest

Example 65. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 4.0 kg of locust bean gum, 0.02 kg of carmine and water up to 100 kg, obtaining a composition of 65 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carob Gum 4.0 Dye 0.02 Water Rest

Example 66. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15.0 kg of locust bean gum, 0.05 kg of carmine and water up to 100 kg, obtaining a composition of 66 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Carob Gum 15.0 Dye 0.05 Water Rest

Example 67. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 4.0 kg of guar gum and water up to 100 kg are mixed, obtaining composition 67 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Guar gum 4.0 Dye 0.02 Water Rest

Example 68. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of guar gum, 0.05 kg of carmine and water to 100 kg, obtaining a composition of 68 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Guar gum 15.0 Dye 0.05 Water Rest

Example 69. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 4.0 kg of locust bean gum, 0.02 kg of carmine and whey up to 100 kg, obtaining a composition of 69 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carob Gum 4.0 Dye 0.02 Milk serum Rest

Example 70. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15.0 kg of locust bean gum, 0.05 kg of carmine and whey up to 100 kg, obtaining a composition of 70 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Carob Gum 15.0 Dye 0.05 Milk serum Rest

Example 71. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 4.0 kg of guar gum and whey to 100 kg, obtaining a composition of 71 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Guar gum 4.0 Dye 0.02 Milk serum Rest

Example 72. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of guar gum, 0.05 kg of carmine and whey up to 100 kg, obtaining a composition of 72 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Guar gum 15.0 Dye 0.05 Milk serum Rest

Example 73. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 4.0 kg of locust bean gum, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and milk up to 100 kg are mixed, obtaining composition 73 in the following ratio of components, wt.% :

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carob Gum 4.0 Polyethylene glycol 3.0 Dye 0.02 Milk Rest

Example 74. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15.0 kg of locust bean gum, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 74 in the following ratio of components, wt .%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Carob Gum 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk Rest

Example 75. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of carmine, 3.0 kg of polyethylene glycol, 4.0 kg of guar gum and milk up to 100 kg, obtaining a composition of 75 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Guar gum 4.0 Polyethylene glycol 3.0 Dye 0.02 Milk Rest

Example 76. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of guar gum, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and milk up to 100 kg, obtaining a composition of 76 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Guar gum 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk Rest

Example 77. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 4.0 kg of locust bean gum, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and water up to 100 kg, obtaining a composition of 77 in the following ratio, wt.% :

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carob Gum 4.0 Polyethylene glycol 3.0 Dye 0.02 Water Rest

Example 78. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15.0 kg of locust bean gum, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and water up to 100 kg, obtaining a composition of 78 in the following ratio, wt. .%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Carob Gum 15.0 Polyethylene glycol 20,0 Dye 0.05 Water Rest

Example 79. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.02 kg of carmine, 4.0 kg of guar gum, 3.0 kg of polyethylene glycol and water are mixed up to 100 kg, obtaining a composition of 79 in the following ratio, wt.%:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Guar gum 4.0 Polyethylene glycol 3.0 Dye 0.02 Water Rest

Example 80. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of guar gum, 20.0 kg of polyethylene glycol 0.05 kg of carmine and water up to 100 kg, obtaining a composition of 80 in the following ratio, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Guar gum 15.0 Polyethylene glycol 20,0 Dye 0.05 Water Rest

Example 81. Mix 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 4.0 kg of locust bean gum, 3.0 kg of polyethylene glycol, 0.02 kg of carmine and whey up to 100 kg, obtaining a composition of 81 in the following ratio of components, wt. %:

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Carob Gum 4.0 Polyethylene glycol 3.0 Dye 0.02 Milk serum Rest

Example 82. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15.0 kg of locust bean gum, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and whey to 100 kg, obtaining a composition of 82 in the following ratio of components, wt.%:

Zoocoumarin 5,0 Sulfachinoxaline 0.1 Carob Gum 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk serum Rest

Example 83. Mix 0.01 kg of zookoumarin, 0.025 kg of sulfachinoxaline, 0.02 kg of carmine, 3.0 kg of polyethylene glycol, 4.0 kg of guar gum and whey to 100 kg, obtaining a composition of 83 in the following ratio, wt.% :

Zoocoumarin 0.01 Sulfachinoxaline 0,025 Guar gum 4.0 Polyethylene glycol 3.0 Dye 0.02 Milk serum Rest

Example 84. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of guar gum, 20.0 kg of polyethylene glycol, 0.05 kg of carmine and whey up to 100 kg, obtaining a composition of 84 in the following ratio, wt.% :

Zoocoumarin 5,0 Sulfachinoxaline 0.5 Guar gum 15.0 Polyethylene glycol 20,0 Dye 0.05 Milk serum Rest

Example 85. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, 0.01 kg of preservative potassium sorbate and water up to 100 kg are added to obtain a composition of 85.

Example 86. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, 2.0 kg of preservative potassium sorbate and water up to 100 kg are added, obtaining composition 86.

Example 87. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, 0.01 kg of preservative of sodium benzoate and water up to 100 kg are added, obtaining composition 87.

Example 88. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, 2.0 kg of preservative of sodium benzoate and water up to 100 kg are added, obtaining composition 88.

Example 89. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, attractant - sugar - 1.0 kg and water up to 100 kg are added, obtaining the composition 89.

Example 90. Mix 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of xanthan, 0.02 kg of carmine, add attractant - sugar - 1.0 kg and water to 100 kg, obtaining a composition of 90.

Example 91. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, attractant - honey - 1.0 kg and water up to 100 kg are added, obtaining composition 91.

Example 92. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, attractant - honey - 20.0 kg and water up to 100 kg are added, obtaining a composition of 92.

Example 93. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, the attractant is added - sunflower oil - 1.0 kg and water up to 100 kg, obtaining a composition of 93.

Example 94. 0.01 kg of zookoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan gum, 0.02 kg of carmine are mixed, an attractant - sunflower oil - 20.0 kg and water up to 100 kg are added, obtaining a composition of 94.

Example 95. 0.01 kg of zookoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, the attractant is added - corn oil - 1.0 kg and water up to 100 kg, obtaining a composition of 95.

Example 96. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine are mixed, attractant - corn oil - 20.0 kg and water up to 100 kg are added, obtaining a composition of 96.

Example 97. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine and water up to 100 kg are mixed, an attractant is added - wheat at a final concentration of 10.0%, mixed thoroughly, getting the composition 97 .

Example 98. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine and water up to 100 kg are mixed, an attractant is added - wheat in a final concentration of 80.0%, mixed thoroughly, getting composition 98 .

Example 99. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine and water up to 100 kg are mixed, an attractant is added - barley at a final concentration of 10.0%, mixed thoroughly, getting the composition 99 .

Example 100. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine and water up to 100 kg are mixed, an attractant is added - barley at a final concentration of 80.0%, mixed thoroughly, getting the composition 100 .

Example 101. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine and water up to 100 kg are mixed, an attractant is additionally added - sunflower seeds at a final concentration of 10.0%, mix thoroughly to obtain the composition 101.

Example 102. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of carmine and water up to 100 kg are mixed, an attractant is additionally added - sunflower seeds at a final concentration of 80.0%, mixed thoroughly, getting the composition 102.

Example 103. 0.01 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan, 0.02 kg of chlorophyll are mixed, a preservative is added - potassium sorbate - 0.01 kg and water up to 100 kg, additionally an attractant - barley in a final concentration of 10 , 0%, mix thoroughly, getting the composition 103.

Example 104. 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of xanthan, 0.05 kg of chlorophyll are mixed, preservative - potassium sorbate - 2.0 kg and water up to 100 kg are added, additionally attractant - barley in a final concentration of 80 , 0%, mix thoroughly, getting the composition 104.

Example 105. Mix 0.1 kg of zoocoumarin, 0.025 kg of sulfachinoxaline, 0.3 kg of xanthan gum, 0.02 kg of carmuazine, add preservative - sodium benzoate - 0.01 kg and water up to 100 kg, additionally attractant - barley in a final concentration of 10 , 0%, mix thoroughly, getting the composition of 105.

Example 106. 5.0 kg of zoocoumarin, 0.1 kg of sulfachinoxaline, 15 kg of xanthan, 0.05 kg of carmoisine are mixed, a preservative - sodium benzoate - 2.0 kg and water up to 100 kg are added, an additional attractant is added - barley in a final concentration 80.0%, mix thoroughly, getting the composition 106.

Compositions 1-106 and the composition of the prototype was tested as follows.

The tested formulations were used both native and after freezing at a temperature of minus 20 degrees for 24 hours, followed by thawing.

The experiments were performed on rats in accordance with the “Methodological recommendations for assessing the efficacy, toxicity and danger of rodenticides” (approved by GKSEN No. 01-19 / 127-17, 1995). In each experiment, 5 rats quarantined for 2 weeks were taken. Each series of experiments was carried out in three to four times the sequence. All poisoned baits were fed to rats in the presence of alternative (non-poisoned) food. The poisoned bait was given in the feeders; in the same feeders, the poisoned food was also given. Rodent eatability of both bait and alternative food was taken into account daily. Water was given in plenty. Observation of experimental animals was carried out for 21 days, given the timing of intoxication and death. Rodenticidal activity was determined by the percentage of death of rats in the experiments. The dead rodents were subjected to autopsy to determine the cause of death of animals.

The test results showed that rodents consumed gel-like baits better (12.3 ± 1.4 g / head) than food-based baits (10.1 ± 1.2). In the study of native (not frozen) experimental compositions obtained according to examples 1-106, the percentage of death of rodents was 92 ± 1.3%, while when using the control (not frozen) - 71.4 ± 1.8% . Tests of samples of the compositions made according to examples 1-106, subjected to freezing-defrosting and the prototype, also subjected to freezing-defrosting, showed that when using the experimental compositions obtained according to examples 1-106, the percentage of death was 86 ± 2.1%, in while when using the prototype - 65 ± 1.6%.

Thus, the claimed composition allows you to effectively fight rodents at any time of the year, including at sub-zero temperatures, including those resistant to anticoagulants.

Claims (24)

1. Rodenticidal composition, characterized in that it includes an anticoagulant, a gelling agent, a dye and water or milk or milk whey, while it contains zoocoumarin as an anticoagulant, contains xanthan or carrageenan, or a mixture of xanthan and carob gum, as a gelling agent, taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture of carrageenan and carob gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture xanthan gum and guar gum taken in ve the ratio of (1-9) :( 1-9), respectively, additionally contains sulfachinoxaline in the following ratio of components, wt.%:
Zoocoumarin 0.01-5.0 Sulfachinoxaline 0.025-0.1
Xanthan, or carrageenan, or a mixture of xanthan
and carob gums taken in weight
ratio equal to (1-9) :( 1-9), respectively,
or a mixture of carrageenan and carob gum,
taken in a weight ratio equal to (1-9) :( 1-9),
respectively, or a mixture of xanthan and guar
gums taken in a weight ratio equal to
(1-9) :( 1-9), respectively 0.3-15 Dye 0.02-0.05 Water, or milk, or whey Rest 2. The rodenticidal composition according to claim 1, characterized in that the dye contains carmine, or carmuazine, or chlorophyll, or methylene blue. 3. The rodenticidal composition according to claim 1, characterized in that it further comprises a preservative - potassium sorbate or sodium benzoate - in a final concentration of 0.01-2.0%. 4. The rodenticidal composition according to claim 1, characterized in that it further comprises an attractant. 5. The rodenticidal composition according to claim 4, characterized in that it contains sugar or honey or vegetable oil — sunflower or corn oil — in a final concentration of 1-20% as an attractant. 6. The rodenticidal composition according to claim 4, characterized in that as an attractant contains grain - wheat, or barley, or sunflower seeds - in a final concentration of 10-80%. 7. Rodenticidal composition, characterized in that it includes an anticoagulant, a gelling agent, a dye and water or milk or milk whey, while it contains zoocoumarin as an anticoagulant, additionally contains xanthan or carrageenan, or a mixture of xanthan and carob gum as a gelling agent taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture of carrageenan and locust bean gum, taken in a weight ratio equal to (1-9) :( 1-9), respectively, or a mixture of xanthan and guar kam di, taken in a weight ratio equal to (1-9) :( 1-9), respectively, as a stabilizer - polyethylene glycol sulfahinoksalin further comprises the following component ratio, wt.%:
Zoocoumarin 0.01-5.0 Sulfachinoxaline 0.025-0.1
Xanthan, or carrageenan, or a mixture of xanthan
and carob gums taken in weight
ratio equal to (1-9) :( 1-9), respectively,
or a mixture of carrageenan and carob gum
tree taken in a weight ratio equal to
(1-9) :( 1-9), respectively, or a mixture of xanthan
and guar gum, taken in a weight ratio,
equal to (1-9) :( 1-9), respectively 0.3-15 Polyethylene glycol 3.0-20.0 Dye 0.02-0.05 Water, or milk, or whey Rest 8. The rodenticidal composition according to claim 7, characterized in that the dye contains carmine, or carmuazine, or chlorophyll, or methylene blue. 9. The rodenticidal composition according to claim 7, characterized in that it further comprises a preservative - potassium sorbate or sodium benzoate - in a final concentration of 0.01-2.0%. 10. The rodenticidal composition according to claim 7, characterized in that it further comprises an attractant. 11. The rodenticidal composition of claim 10, wherein the attractant contains sugar, or honey, or vegetable oil - sunflower or corn oil - in a final concentration of 1-20%. 12. The rodenticidal composition of claim 10, wherein the attractant contains grain - wheat, or barley, or sunflower seeds - in a final concentration of 10-80%. 13. A rodenticidal composition, characterized in that it includes an anticoagulant, a gelling agent, a dye and water or milk or milk whey, while it contains zoocoumarin as an anticoagulant, characterized in that it additionally contains locust bean gum or guar gum, additionally contains sulfachinoxaline in the following ratio, wt.%:
Zoocoumarin 0.01-5.0 Sulfachinoxaline 0.025-0.1 Locust bean gum, or guar gum 4.0-15 Dye 0.02-0.05 Water, or milk, or whey Rest 14. The rodenticidal composition according to item 13, wherein the dye contains carmine, or carmuazine, or chlorophyll, or methylene blue. 15. The rodenticidal composition according to p. 13, characterized in that it further comprises a preservative - potassium sorbate or sodium benzoate - in a final concentration of 0.01-2.0%. 16. The rodenticidal composition according to p. 13, characterized in that it further comprises an attractant. 17. The rodenticidal composition according to clause 16, wherein the attractant contains sugar, or honey, or vegetable oil - sunflower or corn oil - in a final concentration of 1-20%. 18. The rodenticidal composition according to clause 16, characterized in that as an attractant contains grain - wheat, or barley, or sunflower seeds - in a final concentration of 10-80%. 19. A rodenticidal composition, characterized in that it includes an anticoagulant, a gelling agent, a dye and water or milk or milk whey, while it contains zoocoumarin as an anticoagulant, characterized in that it additionally contains locust bean gum or guar gum, in the stabilizer is polyethylene glycol, additionally contains sulfachinoxaline in the following ratio of components, wt.%:
Zoocoumarin 0.01-5.0 Sulfachinoxaline 0.025-0.1 Locust bean gum, or guar gum 4.0-15 Dye 0.02-0.05 Polyethylene glycol 3.0-20.0 Water, or milk, or whey Rest 20. The rodenticidal composition according to claim 19, characterized in that the dye contains carmine, or carmuazine, or chlorophyll, or methylene blue. 21. The rodenticidal composition according to claim 19, characterized in that it further comprises a preservative - potassium sorbate or sodium benzoate - in a final concentration of 0.01-2.0%. 22. The rodenticidal composition according to claim 19, characterized in that it further comprises an attractant. 23. The rodenticidal composition according to item 22, wherein the attractant contains sugar, or honey, or vegetable oil - sunflower or corn oil - in a final concentration of 1-20%. 24. The rodenticidal composition according to item 22, wherein the attractant contains grain - wheat, or barley, or sunflower seeds - in a final concentration of 10-80%.