RU2500400C2 - Применение производных пурина для изготовления лекарственного препарата - Google Patents
Применение производных пурина для изготовления лекарственного препарата Download PDFInfo
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- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- CMZUMMUJMWNLFH-UHFFFAOYSA-N sodium metavanadate Chemical compound [Na+].[O-][V](=O)=O CMZUMMUJMWNLFH-UHFFFAOYSA-N 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
- 229910000166 zirconium phosphate Inorganic materials 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0706390A FR2920776B1 (fr) | 2007-09-12 | 2007-09-12 | Utilisation de derives de purine pour la fabrication d'un medicament |
| FR0706390 | 2007-09-12 | ||
| PCT/FR2008/001278 WO2009068761A2 (fr) | 2007-09-12 | 2008-09-12 | Utilisation de derives de purine pour la fabrication d'un medicament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2010108505A RU2010108505A (ru) | 2011-10-20 |
| RU2500400C2 true RU2500400C2 (ru) | 2013-12-10 |
Family
ID=39382006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010108505/15A RU2500400C2 (ru) | 2007-09-12 | 2008-09-12 | Применение производных пурина для изготовления лекарственного препарата |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8431583B2 (enExample) |
| EP (1) | EP2187889B1 (enExample) |
| JP (1) | JP5485893B2 (enExample) |
| KR (1) | KR20100075908A (enExample) |
| CN (1) | CN101918000B (enExample) |
| BR (1) | BRPI0816810A2 (enExample) |
| CA (1) | CA2699590A1 (enExample) |
| DK (1) | DK2187889T3 (enExample) |
| ES (1) | ES2444419T3 (enExample) |
| FR (1) | FR2920776B1 (enExample) |
| MX (1) | MX2010002680A (enExample) |
| RU (1) | RU2500400C2 (enExample) |
| WO (1) | WO2009068761A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2920776B1 (fr) | 2007-09-12 | 2012-09-28 | Centre Nat Rech Scient | Utilisation de derives de purine pour la fabrication d'un medicament |
| WO2010103473A1 (en) * | 2009-03-10 | 2010-09-16 | Chu De Brest | Method of treatment of polycystic diseases and chronic lymphocytic leukemia |
| WO2013130461A1 (en) * | 2012-02-29 | 2013-09-06 | The Scripps Research Institute | Wee1 degradation inhibitors |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998005335A1 (en) * | 1996-08-02 | 1998-02-12 | Cv Therapeutics, Inc. | PURINE INHIBITORS OF CYCLIN DEPENDENT KINASE 2 AND IλB-$g(a) |
| WO2003002565A1 (en) * | 2001-06-27 | 2003-01-09 | Cyclacel Limited | 2,6,9-substituted purine derivatives and their use n the treatment of proliferative disorders |
| WO2003022805A2 (en) * | 2001-09-11 | 2003-03-20 | Albany Molecular Research, Inc. | Heterocycle substituted purines as antiproliferative agents |
| WO2005016528A2 (en) * | 2003-08-15 | 2005-02-24 | Irm Llc | 6-substituted anilino purines as rtk inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6627633B2 (en) * | 1999-03-17 | 2003-09-30 | Albany Molecular Research, Inc. | 6-substituted biaryl purine derivatives as potent cyclin/CDK inhibitors and antiproliferative agents |
| US6969720B2 (en) * | 1999-03-17 | 2005-11-29 | Amr Technology, Inc. | Biaryl substituted purine derivatives as potent antiproliferative agents |
| US6667311B2 (en) * | 2001-09-11 | 2003-12-23 | Albany Molecular Research, Inc. | Nitrogen substituted biaryl purine derivatives as potent antiproliferative agents |
| GB0315259D0 (en) | 2003-06-30 | 2003-08-06 | Cyclacel Ltd | Use |
| FR2920776B1 (fr) | 2007-09-12 | 2012-09-28 | Centre Nat Rech Scient | Utilisation de derives de purine pour la fabrication d'un medicament |
-
2007
- 2007-09-12 FR FR0706390A patent/FR2920776B1/fr active Active
-
2008
- 2008-09-12 KR KR1020107007886A patent/KR20100075908A/ko not_active Ceased
- 2008-09-12 WO PCT/FR2008/001278 patent/WO2009068761A2/fr not_active Ceased
- 2008-09-12 CN CN2008801067270A patent/CN101918000B/zh not_active Expired - Fee Related
- 2008-09-12 MX MX2010002680A patent/MX2010002680A/es active IP Right Grant
- 2008-09-12 BR BRPI0816810A patent/BRPI0816810A2/pt not_active IP Right Cessation
- 2008-09-12 JP JP2010524542A patent/JP5485893B2/ja not_active Expired - Fee Related
- 2008-09-12 CA CA2699590A patent/CA2699590A1/fr not_active Abandoned
- 2008-09-12 ES ES08855583.4T patent/ES2444419T3/es active Active
- 2008-09-12 RU RU2010108505/15A patent/RU2500400C2/ru not_active IP Right Cessation
- 2008-09-12 US US12/675,945 patent/US8431583B2/en not_active Expired - Fee Related
- 2008-09-12 DK DK08855583.4T patent/DK2187889T3/da active
- 2008-09-12 EP EP08855583.4A patent/EP2187889B1/fr not_active Not-in-force
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998005335A1 (en) * | 1996-08-02 | 1998-02-12 | Cv Therapeutics, Inc. | PURINE INHIBITORS OF CYCLIN DEPENDENT KINASE 2 AND IλB-$g(a) |
| WO2003002565A1 (en) * | 2001-06-27 | 2003-01-09 | Cyclacel Limited | 2,6,9-substituted purine derivatives and their use n the treatment of proliferative disorders |
| WO2003022805A2 (en) * | 2001-09-11 | 2003-03-20 | Albany Molecular Research, Inc. | Heterocycle substituted purines as antiproliferative agents |
| WO2005016528A2 (en) * | 2003-08-15 | 2005-02-24 | Irm Llc | 6-substituted anilino purines as rtk inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2444419T3 (es) | 2014-02-25 |
| KR20100075908A (ko) | 2010-07-05 |
| DK2187889T3 (da) | 2014-02-03 |
| BRPI0816810A2 (pt) | 2017-05-16 |
| CA2699590A1 (fr) | 2009-06-04 |
| WO2009068761A3 (fr) | 2010-01-07 |
| RU2010108505A (ru) | 2011-10-20 |
| FR2920776A1 (fr) | 2009-03-13 |
| CN101918000B (zh) | 2012-11-21 |
| EP2187889A2 (fr) | 2010-05-26 |
| CN101918000A (zh) | 2010-12-15 |
| US20100311768A1 (en) | 2010-12-09 |
| EP2187889B1 (fr) | 2013-11-06 |
| JP2010539146A (ja) | 2010-12-16 |
| JP5485893B2 (ja) | 2014-05-07 |
| MX2010002680A (es) | 2010-08-26 |
| FR2920776B1 (fr) | 2012-09-28 |
| WO2009068761A2 (fr) | 2009-06-04 |
| US8431583B2 (en) | 2013-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20180913 |