RU2457842C2 - Способ предотвращения и лечения болезни печени с использованием антагонистов рецептора аденозина a2b - Google Patents
Способ предотвращения и лечения болезни печени с использованием антагонистов рецептора аденозина a2b Download PDFInfo
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- RU2457842C2 RU2457842C2 RU2008137279/15A RU2008137279A RU2457842C2 RU 2457842 C2 RU2457842 C2 RU 2457842C2 RU 2008137279/15 A RU2008137279/15 A RU 2008137279/15A RU 2008137279 A RU2008137279 A RU 2008137279A RU 2457842 C2 RU2457842 C2 RU 2457842C2
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- Prior art keywords
- formula
- methyl
- amino
- dione
- compounds
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Classifications
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- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US7317017B2 (en) * | 2002-11-08 | 2008-01-08 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| US20080318983A1 (en) * | 2001-11-09 | 2008-12-25 | Rao Kalla | A2b adenosine receptor antagonists |
| US20080194593A1 (en) * | 2001-11-09 | 2008-08-14 | Rao Kalla | A2b adenosine receptor antagonists |
| EP1658291B1 (en) * | 2003-08-25 | 2013-10-02 | Dogwood Pharmaceuticals, Inc. | Substituted 8-heteroaryl xanthines |
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| NO20083968L (no) | 2008-12-15 |
| WO2007109547A3 (en) | 2007-11-29 |
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| AU2007227021A1 (en) | 2007-09-27 |
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| NZ571324A (en) | 2011-07-29 |
| JP2013049719A (ja) | 2013-03-14 |
| RU2008137279A (ru) | 2010-03-27 |
| KR20080107416A (ko) | 2008-12-10 |
| CN101405003A (zh) | 2009-04-08 |
| ZA200807894B (en) | 2009-05-27 |
| US8609671B2 (en) | 2013-12-17 |
| US7795268B2 (en) | 2010-09-14 |
| US20140243358A1 (en) | 2014-08-28 |
| US20070219221A1 (en) | 2007-09-20 |
| MX2008011828A (es) | 2008-09-29 |
| KR101428113B1 (ko) | 2014-08-07 |
| JP2009530413A (ja) | 2009-08-27 |
| CA2646333C (en) | 2014-06-17 |
| CN101405003B (zh) | 2011-05-11 |
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