RU2429814C1 - Dental colourant - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: colourant contains, wt %: pigments - 1.00-10.00, calcium hydroxyapatite - 0.10-5.00, a filming agent - copal resin - 21.00-35.00, a plasticiser - dibutylphthalate or dioxylphthalate - 0.01-0.55, a solvent - ethyl or isopropyl alcohol - up to 100. As an ingredient, the agent can contain calcium hydroxyapatite in the form a fine-dispersed powder or in the form of 0.2-20 % alcoholic colloidal solution of nano-sized hydroxyapatite. The colorant can contain interferent pigments and glitter-effect pigments. The offered formulation is characterised by ease and convenience of application, drying of the applied coating for 90-120 seconds. What is provided is a uniform thickness of the coating which keeps an aesthetic appearance for more than 4 hours after application and if necessary, is easily removed from the surface of teeth by means of a tooth-brush.

EFFECT: lower thermal and taste hypersensitivity of teeth both when applied on teeth, and after removed.

4 cl, 11 ex

Description

The invention relates to decorative cosmetics and can be used for staining teeth and hiding defects in the color of teeth without dental intervention.

It is known that with age, teeth in people acquire a yellowish tint or darken, sometimes the color of enamel changes due to dental intervention or the use of certain medications. However, there are cases when the tooth enamel does not differ in whiteness from nature. Therefore, in recent years, to eliminate such defects, along with traditional whitening using means such as peroxide active substances, cosmetic care has become popular by applying compositions containing white dyes to the teeth.

For example:

1. Known dental kit according to US patent No. 6537360, including:

- a composition containing zinc oxide, polyacrylic acid and a synthetic film former, which is mixed with water immediately before application to the tooth enamel;

- a coating varnish applied to the teeth on top of the above composition after it has dried, containing film-forming agents of synthetic (polyvinyl acetate, alkyl acrylate copolymers) or natural (shellac) origin dissolved in water or alcohol.

This coating has a color close to the color of natural teeth, sufficient durability and can be easily removed if necessary.

Its disadvantage is the difficulty in preparing the composition for application, the drying time after applying both the composition and the top coat (each coating dries from 3 to 5 minutes), as well as the fact that this coating causes some irritation of the oral mucosa and causes tooth hypersthesia.

2. A dentifrice is known according to US Pat. No. 6,048,913, which is a synthetic polymer dissolved in C _1-5 alcohol that has one or more fragments in its structure containing the remainder of phosphoric acid, its salts and halides with a molecular weight of 100,000-5,000,000 having the property of a slight etching effect of tooth enamel, which is the reason for the increased adhesion of this agent. To give white enamel to the teeth, a white dye, titanium dioxide, has been added to this composition.

The disadvantages of this tool is that it is based on a synthetic polymer, and the removal of this composition from the teeth is carried out only using ethanol or a special tool to remove the composition, which is not acceptable for everyone.

3. Known technical solutions using natural resins as the film former. For example, the solution for coating the teeth according to US patent No. 5693313, containing a film former, namely shellac or a mixture of shellac with vinyl acetate, and mainly ethanol as a solvent, which also includes a colored pigment represented by titanium oxide and mica pigment. This solution for coating the teeth provides stability of the dispersion, the luster of the coating itself. But dental compositions based on shellac are easily removed from the teeth during meals, give an unnaturally white shade to the teeth some time after applying the varnish. Therefore, to increase adhesion and prevent the appearance of unnatural whiteness over time, a methacrylic copolymer modified with polymers containing both carboxy and amino groups was added to this solution.

The disadvantage is that the presence of modified synthetic methacrylic copolymers in the solution may lead to some irritation of the oral mucosa or cause allergic reactions. In addition, to achieve the required whiteness of the solution containing shellac (it has an obvious brown hue), it is necessary to add a large number of pigments, which reduces the adhesion and elasticity of the film, or requires additional costs to eliminate the color of the resin.

4. It is also known a tool according to US 2002004190 A1, publ. January 10, 2002, where, as an option, it is proposed to use 5–20% copal resin as a natural film-forming agent together with high-molecular fat cetostearyl alcohol in an amount of 1–20%, which is both a stabilizer and surfactant, and peroxides that are activated when bleaching agents are selected exposure to saliva, which leads to the release of hydrogen peroxide, which penetrates the enamel and dentin, whitening stains or yellowness on the teeth. The disadvantage of this tool is the destructive effect of peroxides on the tooth enamel, therefore it can be used only under the supervision of a doctor and is not suitable for people who have thin and weak enamel or increased sensitivity of the gums.

5. Closest to the claimed technical solution is a coating composition for changing the color of teeth, known from WO 2007002887, publ. January 4, 2007 (also published on August 10, 2009 as application of the Russian Federation No. 2008103004). The description of the publication WO 2007002887 indicates that the composition may include various dyes, as well as dye hydroxyapatite, including nanoscale; alcohol, for example ethanol; and besides - thickeners, stabilizers, flavorings, softeners, etc. An acrylate polymer containing tert-butylate, ethyl acrylate and methacrylic acid is used as the film former. So, in the description of the prototype in examples 1-5, as a film former, LUVIMER® 30E is given, which is a copolymer of ethyl acrylate, tert-butyl acrylate and methacrylic acid. And in examples 2, 3 and 5, the polymer film-forming agent LUVISKOL® VA 37E is additionally formed, formed by 50% ethanol and 50% vinylpyrrolidone copolymer. Both copolymers are recommended by the manufacturer BASF Corporation, Ledgewood, New Jersey, United States of America for use in hair care products (application US No. 10911488 of 08.08.2004, RF patent No. 2398565, http://www.basf-korea.co .kr / 02_products / 04).

The disadvantage of the prototype is the presence in the tool of methacrylic acid, which creates the effect of "etching" of the tooth enamel, and also irritates the oral mucosa (http://www.xumuk.ru/encyklopedia/2526.html). In addition, the introduction of a significant amount of dye, the particle size of which reaches 500 μm (formula 11), in a total amount of up to 50% (formula 12) leads to unpleasant sensations of roughness on the teeth. From a chemical point of view, when particles of such sizes are introduced, up to 20% of these compositions lose their adhesion to the tooth both due to COOH groups and due to a decrease in the penetrating ability of the composition into the tooth structure. In addition, as is known from US Pat. No. 6,537,360, alkyl acrylate copolymer coatings have the ability to dry for a long time, and the addition of dyes, pigments and other substances, materials or particles in an amount up to 50% further contributes to an increase in the drying time of the coating. All this creates the complexity of applying the product without the participation of a dentist.

The objective of the invention is to expand the arsenal of funds for cosmetic dental care, making it possible to safely use the proposed tool to obtain coatings of different colors on the teeth, not only with the help of specialists in dental offices, beauty salons, but also at home or in production conditions.

The proposed tool provides the following technical results:

- does not cause allergic reactions and irritation of the oral mucosa;

- creates the effect of the absence of teeth (black color) or the effect of the presence of gold (gold color) or metal (silver color) teeth in a theater or concert activity;

- makes it possible to stain teeth in various colors from white to black, as well as using the glitter effect, which will allow using the tool both in cinema and theater activities, and in everyday life among young people, for example, at discos;

- ease of application, which eliminates the need for specialist help;

- quick, within 90-120 s, drying of the coating after applying the product to the tooth enamel;

- sufficiently high adhesive properties of the agent, i.e. the ability to save the resulting coating without changing more than 4 hours;

- reduction of tooth hypersensitivity to temperature and taste effects both while the product is on the teeth and after its removal;

- the ability to completely remove the resulting coating, if necessary, by conventional brushing with a toothbrush.

The problem is solved using the proposed tool, which includes (in wt.%):

Kopalovaya resin 21.00-35.00 Plasticizer 0.01-0.35 Hydroxyappatite Calcium 0.10-5.00 Pigments 1.00-10.00 Isopropyl or ethyl alcohol up to 100

A similar composition in the claimed quantitative ratios of the film former — copal resin and plasticizer — dibutyl phthalate or dioctyl phthalate — was not found in any of the available sources, which confirms the compliance of the claimed agent with the “novelty” criterion. The achievement of the claimed technical result clearly does not follow from the prior art, especially with respect to the drying speed, which in turn provides the possibility of using the product without the participation of a specialist, i.e. allows you to recognize the claimed tool meets the criterion of "inventive step".

Of all the possible variants of natural and synthetic resins as a film former, for the purposes of the invention, the most preferred is kopal resin as a natural substance with antiseptic and bactericidal properties, and therefore it is allowed for use in the perfumery, cosmetic and medical (dentistry) industries, as well as from the point of view adhesive properties and plasticity of the film after evaporation of the solvent (alcohol). An important factor is also that the color of the kopal lacquer does not have a clear brown hue, like shellac.

When less than 10% of kopalovoy resin is introduced into the composition, the viscosity of the agent is insignificant, it can drain when applied to the enamel of the teeth, the film does not have the necessary gloss. And if the film former contains more than 35%, it is difficult to evenly apply the agent on the tooth enamel due to the increase in viscosity, after application it dries longer and the adhesive strength of the resulting film decreases. The content of copal resin is preferable 21-30%, which ensures the formation of a uniform film, gloss and the necessary adhesion with tooth enamel.

To give the tool optimal values of ductility, viscosity and thixotropy, it additionally contains a plasticizer, the role of which in the tool is played by dibutyl phthalate or dioctyl phthalate, which are a low-viscosity transparent liquid with a slightly yellowish tint. To maintain plasticity and prevent premature formation of microcracks and "chips" of the coating on the teeth, it is preferable to add 0.15-0.35% plasticizer. Less than 0.01% - low ductility. More than 0.5% increases the drying time of the film on the teeth up to 5-10 minutes.

Calcium hydroxyapatite, which is the main component of tooth enamel, gives additional properties to the product, namely it helps to remineralize the teeth, as well as reduce hypersensitivity to temperature and taste effects both during the film's presence on the teeth and after its removal. Good results are given by the administration of hydroxyapatite in the form of a fine powder. But it is most preferable to introduce 0.2-20% alcohol colloid (gel) of nanoscale hydroxyapatite with a polycrystalline structure, the particles of which consist of elongated crystallites with sizes of 10-20 nm, oriented in a certain way and arranged in chains, including parallel and agglomerated, which the length does not exceed 100-200 nm, the width is 30-40 nm.

To remineralize tooth enamel and reduce hypersthesia, calcium hydroxyapatite in an amount of 0.1-5.0 wt.% Is additionally introduced into the product, because less than 0.1%, the effect of reducing hypersthesia to temperature and taste is not significant, and more than 5% - an undesirable effect on the color of the agent is manifested.

To obtain the desired color, the composition may contain both pigments, which are dyes of a certain color, and interference pigments, which themselves are not dyes, but provide the desired color effect due to the multiple reflection and refraction of incident light in different coating layers, resulting in reflected rays either amplify or cancel each other. The best results for obtaining a high-quality film on teeth after applying a dentifrice are achieved using interference pigments with a particle size of 5 to 60 microns. Introduction to the composition of the product less than 1 wt.% Pigments leads to too much transparency of the tool on the teeth, the need for additional layers to obtain the desired color. More than 10 wt.% - leads to a decrease in adhesion and coating strength. A pigment can be added to the composition of the product to obtain a glitter effect in a ratio of 1: 3-1: 10 to the main pigment of the desired color.

In order to obtain the natural white shade most demanded for cosmetic purposes on the teeth, Timiron Supersheen MP-1001 and / or Timiron Supersilk MP-1005 and / or Iriodin® 6103 Icy White pigments are added to the composition with the possible addition of Ronastan Blue Sparks.

- The pigments Timiron Supersheen MP-1001 and Timiron Supersilk MP-1005 are silver-white powder of thin mica plates modified with titanium dioxide with a particle size of 5.0-25.0 microns. This pigment is non-toxic and safe for use in cosmetics (Directive 67/548 / EEC). High hiding power, silky sheen, natural enamel color are achieved with a content of 2-4.0% Timiron Supersheen MP-1001, MP-1005 pigment. Less than 1% - the film is transparent, does not give the necessary hiding power, more than 5% - the naturalness of tooth enamel disappears.

- The pigment Iriodin® 6103 Icy White is a synthetically obtained mica with a particle size of 10-60 microns, coated with titanium dioxide and stabilized against yellowing. Provides a clear silver-white tint, high hiding power and gloss. Suitable for combining it with light organic and inorganic pigments to create different shades. The most preferred content in the composition is from 2 to 5%.

- The Ronastan Blue Sparks pigment, which is additionally added to produce a glitter effect, is a white with a blue sparkling effect powder of calcium aluminoborsilicate plates encapsulated in layers of silicon and titanium dioxide with a particle size of 20-200 microns. This pigment is also non-toxic and safe for use in cosmetics (Directive 67/548 / EEC). The most preferred content of 0.3-1.2% gives the gloss of tooth enamel, the color of the film is as close as possible to the color of natural teeth, and the surface of the film is smooth and glossy. Because the digging-based film thickness is less than 10.0 μm, the addition of more than 1.5% pigment can cause a roughness on the teeth, and less than 0.1% does not create the desired glitter effect. To obtain a different color, pigments of the corresponding desired shade can be added to the composition of the product. For example, to obtain black pigment Microna Matte Black, or Mika Black, or Color Blondstoe Blue; to obtain gold color (effect of golden teeth) Timiron Gold Plus MP-25, or Timiron Silk Gold, or Timiron Starlight Gold, or Timiron Splendid Copper, to obtain Timiron Silk Blue, to obtain blue - Colorona Light Blue, silver - Timiron Arctis Silver or Biron Silver CO. Ronastan Noble Sparks or Ronastan Aqua Sparks pigments can also be used to produce a glitter effect. To obtain a golden glitter effect, you can use the pigment Timiron Splendid Gold. The above examples do not exhaust the possible uses of other pigments that are allowed for use for these purposes.

Ethyl or isopropyl alcohols are used as a solvent, because it is these alcohols that provide the necessary drying time for the applied coating.

In addition, in the claimed composition may be introduced:

- hydroxypropyl cellulose (GOC) is a non-ionic cellulose ether that can dissolve in both aqueous and polar organic solvents. Films and coatings with the addition of HPC have good elasticity;

- ethyl cellulose is a film-forming cellulose ether, the addition of which, in addition to improving the rheological properties, improves the adhesion and water resistance of the coating.

For the purposes of the invention, it is permissible to introduce from 0.40 to 1.20 wt.% HPC and / or ethyl cellulose into the composition, individually or together, in any ratio.

Allowed the introduction of any alcohol-soluble fragrances in an amount of 0.01-0.10 wt.%, Which will give the tool the desired aroma, but their presence will not affect the main characteristics of the tool.

The tool is prepared as follows.

Kopalova resin with continuous stirring is dissolved in alcohol, the resulting solution is filtered on coarse and fine filters, if necessary, a thickener is added with continuous stirring, left to swell for 2-3 hours and again mixed for 6-9 hours, plasticizer is added, then pigments, continuing mixing for 1-3 hours. After this, calcium hydroxyapatite and, if necessary, perfumes are added, while stirring until homogeneous.

The invention is presented in the following drawings.

Figure 1 - image of teeth with a natural color of enamel.

Figure 2 - image of the teeth after applying funds containing interference pigments that impart white color.

Figure 3 - image of the teeth of natural color (1), natural crown (2) and teeth with the applied means to obtain white (3) and golden (4) colors.

Figure 4 - image of the teeth of the artificial jaw with a golden color applied to 1 tooth.

Figure 5 - image of the teeth of the artificial jaw with a black tool applied to 1 tooth.

As an example, 11 variants of compositions with different mass fractions of components and the characteristics of the obtained product by drying time after application to tooth enamel are given.

Example 1. White color.

The product contains (wt.%) Kopal - 10, HPC - 1.00, Timiron Supersheen MP-1001 pigment - 2.85, Ronastan Blue Sparks pigment - 0.56, plasticizer - 0.25, hydroxyapatite - 0.30 and solvent - up to 100%. Drying time - 90 s.

Example 2. White color.

The product contains (wt.%) Kopal - 25.0, GPC - 0.90, Timiron Supersilk MP-1005 pigment - 2.60, Ronastan Blue Sparks pigment - 0.50, plasticizer - 0.25, hydroxyapatite - 4.00 and solvent up to 100%. Drying time - 110 s.

Example 3. White color.

The product contains (wt.%) Kopal - 30.0, HPC - 0.85, Timiron Supersilk MP-1005 pigment - 1.10, Timiron Supersheen MP-1001 pigment - 1.00, Timiron Silk Blue pigment - 0.50, plasticizer - 0.25, hydroxyapatite - 0.2 and solvent - up to 100%. Drying time - 110 s.

Example 4: Black.

The product contains (wt.%) Kopal - 35.0, HPC - 0, 40, pigment Color Blondstoe Blue - 5.2, plasticizer - 0.30, hydroxyapatite - 0.50 and solvent - up to 100%. Drying time - 120 s.

Example 5. Golden color.

The product contains (wt.%) Kopal - 28.0, Timiron Gold Plus MP-25 pigment - 4.5, plasticizer - 0.01, hydroxyapatite - 2.50 and solvent - up to 100%. Drying time - 105 s.

Example 6. Red color.

The product contains (wt.%) Kopal - 27.0, Colorona Cormine Red pigment - 3.50, iron oxide red pigment 216 - 2.0, plasticizer - 0.35, hydroxyapatite - 2.30 and solvent - up to 100%. Drying time 100 s.

Example 7. Blue color.

The product contains (wt.%), Kopal - 28.0, Colorona Light Blue pigment - 4.0, plasticizer - 0.35, hydroxyapatite - 1.50 and solvent - up to 100%. Drying time - 110 s.

Example 8. Violet color.

The product contains (wt.%) Kopal - 27.0, Colorona Magenta pigment - 5.4, plasticizer - 0.25, hydroxyapatite - 1.50 and solvent - up to 100%. Drying time - 105 s.

Example 9. White color with a golden glitter effect.

The product contains (wt.%) Kopal - 18, Timiron Splendid Copper pigment - 3.0, Timiron Splendid Gold pigment - plasticizer - 0.25, hydroxyapatite - 1.50 and solvent - up to 100%. Drying time - 95 s.

Example 10. Silver color.

The product contains (wt.%) Kopal - 25, pigment Biron Silver CO - 6.6, plasticizer - 0.25, hydroxyapatite - 4.85 and solvent - up to 100%. Drying time - 100 s.

Example 11. White color with silver glitter effect.

The product contains (wt.%) Kopal - 27, Ronastan Blue Sparks pigment - 1.00, plasticizer - 0.25, hydroxyapatite - 4.85 and solvent - up to 100%. Drying time - 110 s.

Testing of the above compositions was carried out by applying to tooth enamel cleaned and dried with a cotton ball and checking the quality of the coating four hours after applying the agent.

According to the test results, the drying time of the film is 90-120 s. The simplicity and convenience of applying the product on the teeth, the uniformity of the coating and the thickness of the film obtained on the teeth, and the natural appearance of the teeth immediately after applying the white color are characteristic. When using other pigments, spectacular saturated colors are obtained on the teeth from light to bright shades. Even 4 hours after applying the product, the coating retains an aesthetic appearance. If necessary, the product is easily removed from the surface of the teeth with a toothbrush. A decrease in tooth hypersensitivity to temperature and taste effects was noted both while the product was on the teeth and after its removal.

If it is necessary to give the teeth any other color that is not indicated in the description, a pigment of the necessary color shade is approved for use in decorative cosmetics.

Claims (4)

1. A tool for staining teeth, containing a dye and calcium hydroxyapatite in a total amount of not more than 15%, a film former and alcohol, characterized in that the film former is a copal resin dissolved in ethyl or isopropyl alcohol with dibutyl phthalate or dioctyl phthalate added in the following ratios of components, wt.%:
Kopalovaya resin 21.00-35.00 Dibutyl phthalate or dioctyl phthalate 0.01-0.35 Calcium Hydroxyapatite 0.10-5.00 Pigments 1.00-10.00 Ethyl or isopropyl alcohol up to 100 2. The tool according to claim 1, characterized in that it contains a fine powder of hydroxyapatite. 3. The tool according to claim 1, characterized in that it contains a 0.2-20% alcohol colloidal solution of nanosized hydroxyapatite. 4. The tool according to claim 1, characterized in that it contains interference pigments and a pigment for imparting a glitter effect in a ratio of 1: 3-1: 10.

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