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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
FIELD: medicine.
SUBSTANCE: invention refers to the compound 3-{[5-(azetidine-1-ylcarbonyl)pyrazine-2-yl] oxy}-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}-N-(5-methylpyrazine-5-yl)benzamide or to its pharmaceutically acceptable salt. Also, it refers to a pharmaceutical composition for treating insulin-independent diabetes or obesity containing said compound.
EFFECT: there is produced and described a new compound which can be effective in treating insulin-independent diabetes and obesity.
5 cl, 64 ex
Description
Текст описания приведен в факсимильном виде.
The text of the description is given in facsimile form.
Claims (5)
1. Соединение 3-{[5-(азетидин-1-илкарбонил)пиразин-2-ил]окси}-5-{[(1S)-1-метил-2-(метилокси)этил]окси}-N-(5-метилпиразин-2-ил)бензамид или его фармацевтически приемлемая соль.1. Compound 3 - {[5- (azetidin-1-ylcarbonyl) pyrazin-2-yl] oxy} -5 - {[(1S) -1-methyl-2- (methyloxy) ethyl] oxy} -N- ( 5-methylpyrazin-2-yl) benzamide or a pharmaceutically acceptable salt thereof.2. Соединение по п.1, представляющее собой 3-{[5-(азетидин-1-илкарбонил)пиразин-2-ил]окси}-5-{[(1S)-1-метил-2-(метилокси)этил]окси}-N-(5-метилпиразин-2-ил)бензамид.2. The compound according to claim 1, which is 3 - {[5- (azetidin-1-ylcarbonyl) pyrazin-2-yl] oxy} -5 - {[(1S) -1-methyl-2- (methyloxy) ethyl ] hydroxy} -N- (5-methylpyrazin-2-yl) benzamide.3. Фармацевтическая композиция для лечения диабета 2 типа или ожирения, содержащая соединение по п.1 или 2 вместе с фармацевтически приемлемым разбавителем или носителем.3. A pharmaceutical composition for treating type 2 diabetes or obesity, comprising a compound according to claim 1 or 2 together with a pharmaceutically acceptable diluent or carrier.4. Соединение по п.1 или 2 для применения в лечении диабета 2 типа.4. The compound according to claim 1 or 2 for use in the treatment of type 2 diabetes.5. Соединение по п.1 или 2 для применения в лечении ожирения.
5. The compound according to claim 1 or 2 for use in the treatment of obesity.
RU2008101927/04A2005-07-092006-07-03Heteroarylbenzamide derivatives applied as glk activators in diabetes treatment
RU2415141C2
(en)
Compounds derived from 2- [1-substituted-1h-pyrazolo [3,4-d] pyrimidin-4-yl] (thio, oxy or amino) -n- (heteroaryl) -alkanoamides; with activated glucokinase modulator glk or gk; Pharmaceutical composition comprising and use in the treatment of type 2 diabetes and obesity.
COMPOUND DERIVED FROM DEFINED FORMULA DIHYDROQUINAZOLINE, USEFUL FOR THE TREATMENT AND / OR PROFILAXIS OF VIRAL INFECTIONS; PHARMACEUTICAL COMPOSITION THAT INCLUDES THE COMPOUND AND USE OF THE COMPOUND IN THE PREPARATION OF MEDICINES.
Crystalline forms h-1 and t1f-1/2 of n- (tert-butoxycarbonyl) -3-methyl-l-valyl- (4r) -4 - ((7-chloro-4-methoxy-1-isoquinolinyl) oxy) -n - ((1r, 2s) -1 - ((cyclopropylsulfonyl) carbamoyl) -2-vinylcyclopropyl) -l-prolinamide; pharmaceutical composition; and its use for the treatment of hepatitis c virus.
Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood glp-1 level
DERIVATIVES OF 2-OXO-ETHYL-AMINO-PROPIONAMIDE-PYRROLIDIN-2-IL-SUBSTITUTED AS INHIBITORS OF THE BINDING OF THE PROTEIN Smac TO THE INHIBITOR OF THE PROTEIN OF APOPTOSIS
Pharmaceutical composition comprising a dpp iv inhibitor compound with an amino group or a salt thereof, a first diluent, a second diluent, a binder, a disintegrant and a lubricant, useful in the treatment of diabetes mellitus.
COMPOUNDS DERIVED FROM REPLACED BIPIRIDINE; PREPARATION PROCEDURE; PHARMACEUTICAL COMPOSITION; AND USE IN THE TREATMENT AND / OR PROFILAXIS OF DISEASES SUCH AS HYPERTONIA, DIABETES, MYOCARDIAL INFARTS, BETWEEN OTHERS.
a compound or a pharmaceutically acceptable salt or ester thereof, a method for treating or prophylaxis a host infected with a flavivirus, pestivirus or hepacivirus infection, and a pharmaceutical composition for treating a host infected with a flavivirus, pestivirus or hepacivirus