RU2010149302A - Heteroarylbenzamide derivatives for use as GLK activators in the treatment of diabetes - Google Patents
Heteroarylbenzamide derivatives for use as GLK activators in the treatment of diabetes Download PDFInfo
- Publication number
- RU2010149302A RU2010149302A RU2010149302/04A RU2010149302A RU2010149302A RU 2010149302 A RU2010149302 A RU 2010149302A RU 2010149302/04 A RU2010149302/04 A RU 2010149302/04A RU 2010149302 A RU2010149302 A RU 2010149302A RU 2010149302 A RU2010149302 A RU 2010149302A
- Authority
- RU
- Russia
- Prior art keywords
- diabetes
- treatment
- oxy
- compound according
- heteroarylbenzamide
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1. Соединение 3-{[5-(азетидин-1-илкарбонил)пиразин-2-ил]окси}-5-{[(1S)-2-гидрокси-1-метилэтил]окси}-N-(5-метилпиразин-2-ил)бензамид или его фармацевтически приемлемая соль. ! 2. Соединение по п.1, представляющее собой 3-{[5-(азетидин-1-илкарбонил)пиразин-2-ил]окси}-5-{[(1S)-2-гидрокси-1-метилэтил]окси}-N-(5-метилпиразин-2-ил)бензамид. ! 3. Фармацевтическая композиция для лечения диабета 2-го типа или ожирения, содержащая соединение по п.1 или 2 вместе с фармацевтически приемлемым разбавителем или носителем. ! 4. Соединение по п.1 или 2 для применения в лечении диабета 2-го типа. ! 5. Соединение по п.1 или 2 для применения в лечении ожирения. 1. Compound 3 - {[5- (azetidin-1-ylcarbonyl) pyrazin-2-yl] oxy} -5 - {[(1S) -2-hydroxy-1-methylethyl] oxy} -N- (5-methylpyrazine -2-yl) benzamide or a pharmaceutically acceptable salt thereof. ! 2. The compound according to claim 1, which is 3 - {[5- (azetidin-1-ylcarbonyl) pyrazin-2-yl] oxy} -5 - {[((1S) -2-hydroxy-1-methylethyl] oxy} -N- (5-methylpyrazin-2-yl) benzamide. ! 3. A pharmaceutical composition for treating type 2 diabetes or obesity, comprising a compound according to claim 1 or 2 together with a pharmaceutically acceptable diluent or carrier. ! 4. The compound according to claim 1 or 2 for use in the treatment of type 2 diabetes. ! 5. The compound according to claim 1 or 2 for use in the treatment of obesity.
Claims (5)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0514173.4 | 2005-07-09 | ||
GB0514173A GB0514173D0 (en) | 2005-07-09 | 2005-07-09 | Chemical compounds |
GB0516297.9 | 2005-08-09 | ||
GB0516297A GB0516297D0 (en) | 2005-08-09 | 2005-08-09 | Chemical compounds |
GB0523862.1 | 2005-11-24 | ||
GB0524589.9 | 2005-12-02 | ||
GB0524589A GB0524589D0 (en) | 2005-12-02 | 2005-12-02 | Chemical compounds |
GB0607977.6 | 2006-04-22 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2008101927/04A Division RU2415141C2 (en) | 2005-07-09 | 2006-07-03 | Heteroarylbenzamide derivatives applied as glk activators in diabetes treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
RU2010149302A true RU2010149302A (en) | 2012-06-10 |
Family
ID=41150447
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2008101927/04A RU2415141C2 (en) | 2005-07-09 | 2006-07-03 | Heteroarylbenzamide derivatives applied as glk activators in diabetes treatment |
RU2010149302/04A RU2010149302A (en) | 2005-07-09 | 2010-12-03 | Heteroarylbenzamide derivatives for use as GLK activators in the treatment of diabetes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2008101927/04A RU2415141C2 (en) | 2005-07-09 | 2006-07-03 | Heteroarylbenzamide derivatives applied as glk activators in diabetes treatment |
Country Status (1)
Country | Link |
---|---|
RU (2) | RU2415141C2 (en) |
-
2006
- 2006-07-03 RU RU2008101927/04A patent/RU2415141C2/en active
-
2010
- 2010-12-03 RU RU2010149302/04A patent/RU2010149302A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
RU2008101927A (en) | 2009-08-20 |
RU2415141C2 (en) | 2011-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20131204 |