RU2413757C2 - Cleaning composition containing organic catalyst with improved enzyme compatibility - Google Patents

Abstract

FIELD: chemistry.

SUBSTANCE: cleaning compositions contain organic catalysts having improved enzyme compatibility and having the following formulae:

where each R¹ independently denotes a branched alkyl group selected from a group comprising 2-butyloctyl, 2-pentylnonyl, 2-hexyldecyl, isodecyl, isotridecyl and isopentadecyl, or a linear alkyl group containing 11-18 carbon atoms. The composition also contains one or more auxiliary ingredients.

EFFECT: cleaning compositions with efficient bleaching at low water temperature.

15 cl, 16 ex

Description

FIELD OF THE INVENTION

The present invention relates to cleaning compositions containing organic catalysts, and to methods for producing and using such cleaning products.

State of the art

Oxygen bleaches, such as hydrogen peroxide, are usually used to facilitate the removal of stains and dirt from clothing and various surfaces. Unfortunately, such bleaches are extremely temperature dependent. As a result, when such bleaches are used in colder solutions, the whitening effect of such solutions is markedly reduced.

In an effort to solve the aforementioned efficiency problem, a class of materials known as “whitening activators” has been developed in industry. However, since such materials quickly lose their effectiveness in solution at temperatures less than 40 ° C, new organic catalysts have been developed, such as the internal salts of 3,4-dihydro-2- [2- (sulfooxy) decyl] isoquinolinium. In general, although such state-of-the-art catalysts are effective in low water temperatures, they can inactivate certain enzymes. Since most laundry detergents and cleaning compositions are made with enzymes, formulating cleaning products with such catalysts can be problematic.

Thus, there is a need for an inexpensive cleaning composition containing an organic catalyst that can provide a combined effect of versatility, bleaching efficiency at low water temperatures, and enzyme compatibility.

SUMMARY OF THE INVENTION

The present invention relates to cleaning compositions containing organic catalysts having improved compatibility with enzymes, and to methods for their preparation and use.

DETAILED DESCRIPTION OF THE INVENTION

Definitions

As used herein, the term “cleaning composition” includes, unless otherwise indicated: granular or powder form of universal or “heavy duty” detergents, especially laundry detergents; liquid, gel or paste-like form of universal or “heavy duty” detergents, especially the so-called heavy duty liquid types; liquid detergents for delicate fabrics; compositions for manual washing dishes and lightweight compositions for washing dishes, especially compositions with copious foaming; compositions for machine washing dishes, including various tableted, granular, liquid types and types with the addition of rinse aid for domestic and industrial use; liquid detergents and disinfectants, including antibacterial cleansers, washing bars, mouthwashes, dental cleaners, shampoos for cars and carpets, bath cleaners; shampoos and hair rinses; shower gels and bath foams, and metal surface cleaners; as well as auxiliary cleaning agents, such as bleaching additives and stain removers or pre-treatment substances.

As used in this application, the phrase "independently selected from the group consisting of ..." means that the fragments or elements that are selected from the specified Markush formula may be the same, different, or any mixture of elements.

To determine the appropriate values of the parameters of the inventions of the applicant should use the test methods disclosed in the section "Testing methods" of this application.

Unless otherwise indicated, all components or contents of the compositions are based on the active content of these components or compositions and do not take into account impurities, such as residual amounts of solvents or by-products that may be present in commercially available products.

All percentages and ratios are given by weight unless otherwise indicated. All percentages and ratios are based on the entire composition, unless otherwise indicated.

It should be understood that any maximum numerical limitation given in the present description includes any lower numerical value, as if such lower values would be specifically indicated. Each minimum numerical limitation given in the framework of the present description will include any larger numerical limitation, as if such large limitations would be specifically indicated. Any numerical range described herein will include any narrower range falling within it, as if such narrower ranges would be specifically indicated.

All cited documents, in their relevant part, are incorporated into this application by reference; citing any source may not be construed as recognition of its relevance to the present invention.

Organic Catalyst Cleaning Compositions

Applicant has found that a judicious selection of the R ¹ fragment ^{of an} organic catalyst of the present invention leads to improved enzyme compatibility. Without being bound by theory, the applicant believes that this is due to the favorable decomposition of the catalyst in aqueous media as a result of the aforementioned judicious choice of the R ¹ fragment.

In one aspect of the Applicant’s invention, the cleaning compositions comprise an organic catalyst having an enzyme compatibility value of 70 or more, or even 80 or more.

In one aspect of the Applicant’s invention, the cleaning compositions comprise an organic catalyst having an enzyme compatibility value of 70 or more, and one or more auxiliary compounds.

In one aspect of the applicant's invention, the cleaning compositions comprise an organic catalyst having an enzyme compatibility value of 80 or more, and said composition comprises the following auxiliary ingredients: an activated source of peroxygen, an enzyme, and a surfactant.

In one aspect of the applicant's invention, the cleaning compositions comprise an organic catalyst represented by Formula 1 or Formula 2, or mixtures thereof.

where: R ₁ represents a branched alkyl fragment containing from 9 to 24 carbon atoms, or a linear alkyl fragment containing from 11 to 24 carbon atoms; a branched alkyl fragment containing from 9 to 18 carbon atoms, or a linear alkyl fragment containing from 11 to 18 carbon atoms, is selected from the group consisting of 2-propylheptyl, 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, n-dodecyl , n-tetradecyl, n-hexadecyl, n-octadecyl, isononyl, isodecyl and isopentadecyl; or selected from the group consisting of 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, isotridecyl and isopentadecyl.

The composition of the above cleaning compositions, for any object, is brought to a balance (up to 100%) using one or more auxiliary materials.

Methods for preparing suitable organic catalysts

Suitable organic catalysts can be prepared using a variety of reaction reactors and processes, including a batch, semi-batch, and continuous process.

In one of the objects of the invention of the applicant, a method for producing the above catalyst includes the step of reacting a complex of sulfur trioxide and 3,4-dihydroisoquinoline with an epoxide to form said organic catalyst.

In another aspect of the applicant’s invention, a method for producing the above catalyst includes the steps of reacting 3,4-dihydroisoquinoline with a material selected from the group consisting of sulfur trioxide, a source material of sulfur trioxide and mixtures thereof, to form a complex of sulfur trioxide with 3,4- dihydroisoquinoline, and the interaction of such a complex of sulfur trioxide with 3,4-dihydroisoquinoline with an epoxide to obtain the specified organic catalyst.

In another aspect of the applicant’s invention, a method for producing the above catalyst includes the step of reacting 3,4-dihydroisoquinoline with a complex of sulfur trioxide with an epoxide to form said organic catalyst.

In another aspect of the Applicant’s invention, a method for producing the above catalyst includes the steps of reacting an epoxide with a material selected from the group consisting of sulfur trioxide, a source material of sulfur trioxide and mixtures thereof, to form a complex of sulfur trioxide with an epoxide, and reacting such a complex of sulfur trioxide and an epoxide with 3,4-dihydroisoquinoline to obtain the specified organic catalyst.

A variant of the above catalyst containing an oxaziridine ring can be prepared by reacting a variant of said catalyst containing an imine ring with an oxygen carrier, for example with peroxycarboxylic or peroxymonosulfuric acid, for example Oxone®. Such substances can be obtained in situ and used without purification.

Although a person reading the present description, can easily determine the desired reaction conditions and concentrations of reagents, typical reaction conditions of the above objects of the invention of the applicant include a reaction temperature from about 0 ° C to about 150 ° C, or from about 0 ° C to about 125 ° C, reaction pressures from about 0.1 to about 100 atmospheres (atm), from about 0.3 to about 10 atm, or from about 1 atm to about 10 atm; reaction times are from 0.1 hour to about 96 hours, from about 1 hour to about 72 hours, or from about 1 hour to about 24 hours. The interaction can also be carried out in an inert atmosphere or, otherwise, in anhydrous conditions, including, when using a solvent, the use of an anhydrous solvent.

The materials used in the method of the applicant include 3,4-dihydroisoquinoline, epokeides and mixtures thereof, sulfur trioxide, sources of sulfur trioxide and mixtures thereof, and solvents.

When using 3,4-dihydroisoquinoline, the initial reaction mixture usually contains from about 0.5 wt.% To about 70 wt.%, From about 5 wt.% To about 70 wt.% Or from about 10 wt.% To about 50 wt. .% of such material. 3,4-dihydroisoquinoline can be prepared in accordance with the protocol disclosed in Example 1.

When using epoxides, the initial reaction mixture usually contains from about 0.5 wt.% To about 70 wt.%, From about 5 to about 70 wt.%, Or from about 10 wt.% To about 50 wt.% Of such material. Suitable epoxides include, but are not limited to, such as 2-propylheptyl glycidyl ether, 2-butyl octyl glycidyl ether, 2-pentylnonyl glycidyl ether, 2-hexyldecyl glycidyl ether, n-dodecyl glycidyl ether, n-tetradecyl glycidyl ether, n-hexadecyl ether, n-octadecyl glycidyl ether, isononyl glycidyl ether, isodecyl glycidyl ether, isotridecyl glycidyl ether, and mixtures thereof. Such materials may contain oligomeric forms of glycidyl ether, which optionally can be removed before use. 2-Propylheptyl glycidyl ester can be prepared as described in Example 2 of the present description. All other glycidyl ethers mentioned above can be prepared according to the following general protocol according to Example 2 by substituting a suitable alcohol for 2-propylheptanol. Suitable alcohols include 2-propylheptanol, 2-butylheptanol, 2-butyl octanol, 2-pentylnanol, 2-hexyldecanol, n-dodecanol, n-tetradecanol, n-hexadecanol, n-octadecanol, isononanol and isdecanol.

When using sulfur trioxide or its source and mixtures thereof, the initial reaction mixture usually contains from about 0.5 wt.% To about 70 wt.%, From about 5 wt.% To about 70 wt.% Or from about 10 wt.% To about 50 wt.% such a substance. Suitable materials include sulfur trioxide and sulfur trioxide complexes such as a complex of sulfur trioxide with dioxane, sulfur trioxide with pyridine, sulfur trioxide with N, N-dimethylformamide, sulfur trioxide with sulfolane, sulfur trioxide with tetrahydrofuran, sulfur trioxide with diethyl ether, sulfur trioxide with 3,4-dihydroisoquinoline, and mixtures thereof.

Typically, the reaction mixture contains a balanced amount of solvent. When using a solvent, the initial reaction mixture typically contains up to 99 wt.% Solvent, from about 10 wt.% To about 90 wt.% Solvent, or from about 20 wt.% To about 80 wt.% Solvent. Suitable solvents include aprotic, polar, and nonpolar solvents such as acetonitrile, dioxane, methylbutyl ether, tetrahydrofuran, N, N-dimethylformamide, sulfolane, chlorobenzene, toluene, 1,2-dichloroethane, methylene chloride, chloroform, diethyl ether , hexanes, pentanes, benzene, xylene and mixtures thereof. Suitable solvents can be ordered from Aldrich, P.O. Box 2060, Milwaukee, WI 53201, USA.

Cleaning compositions and cleaning composition additives containing organic catalysts of the applicant

The cleaning composition of the present invention can be successfully used, for example, when washing clothes, cleaning hard surfaces, in automatic dishwashers, as well as in cosmetic use, for example for dentures, teeth, hair and skin. However, due to the unique advantages of both improved efficiency at lower solution temperatures and excellent compatibility with enzymes, the organic catalysts of the present invention are ideally suited for use in washing, for example when bleaching fabrics using detergents containing a bleaching agent, or detergents containing bleach. In addition, the organic catalysts of the present invention can be used in both granular and liquid formulations.

The organic catalysts of the present invention can also be used in cleaning additives. A cleaning agent comprising the organic catalysts of the present invention is ideally suited for incorporation into the washing process if additional whitening effectiveness is desired, for example - but not limited to - when cleaning in solution at low temperature. In its simplest form, the additive may be an organic catalyst of the applicant. Preferably, the additive may be packaged in a dosage form for addition in a cleaning process where a source of peroxygen is used and an increase in bleaching efficiency is desired. Such a unit dosage form may comprise a pill, tablet, gel measure or other separate dosage unit, such as pre-measured powders or liquids. To increase the volume, such a composition may include a filler or carrier. Suitable carrier or filler material includes, but is not limited to, various salts of sulfate, carbonate, and silicate, as well as talc, alumina, and the like. The carrier or filler materials for liquid compositions may be water or low molecular weight primary or secondary alcohols, including diols and polyols. Examples of such alcohols include, but are not limited to, methanol, ethanol, propanol, and isopropanol. Compositions may contain from about 5% to about 90% of such materials. Acidic excipients may be used to lower the pH. Alternatively, the cleaning additive may include an activated source of peroxygen, as defined hereinafter, or auxiliary ingredients, as fully defined below.

Applicant's cleaning compositions and cleaning additives require a catalytically effective amount of an applicant's organic catalyst. The required level of such a catalyst can be achieved by adding one or more of the applicant's organic catalyst substances. In practice, but not for the purpose of limiting, the compositions and cleaning methods disclosed herein may comprise of the order of at least 0.001 ppm (ppm), from about 0.001 ppm to about 500 ppm, from about 0.005 ppm to about 150 ppm, or even from about 0.05 ppm to about 50 ppm of the applicant's organic catalyst in a washing liquid. To obtain such levels in a washing liquid, typical compositions of interest may contain from about 0.0002% to about 5%, or even from about 0.001% to about 1.5% of an organic catalyst by weight of the cleaning compositions.

When an applicant’s organic catalyst is used in a granular composition, it may be desirable for the applicant’s organic catalyst to be in the form of encapsulated particles to protect the applicant’s organic catalyst from moisture and / or other components of the granular composition during storage. In addition, encapsulation is also a means of controlling the availability of the applicant’s organic catalyst during the cleaning process and can enhance the whitening efficiency of the applicant’s organic catalyst. In this regard, the applicant’s organic catalyst may be encapsulated by any known encapsulating material.

The encapsulating material typically encapsulates at least a portion, and preferably, the entire organic catalyst of the applicant. Typically, the encapsulating material is a water-soluble and / or water-dispersible material. The encapsulating material may have a glass transition temperature (T _g ) of 0 ° C. or higher.

Preferably, the encapsulating material is selected from the group consisting of carbohydrates, natural or artificial resins, chitin and chitosan, cellulose and its derivatives, silicates, phosphates, borates, polyvinyl alcohol, polyethylene glycol, paraffin waxes, and combinations thereof. Preferably, the encapsulating material is a carbohydrate, usually selected from the group consisting of monosaccharides, oligosaccharides, polysaccharides and combinations thereof. More preferably, the encapsulating material is starch. Preferred starches are described in EP 0922499, US 4977252, US 5354559 and US 5935826.

The encapsulating material may be microspheres made of plastic, for example, from thermoplastics, acrylonitrile, methacrylonitrile, polyacrylonitrile, polymethacrylonitrile, and mixtures thereof; commercially available microspheres sold under the Expancel® brand from Expancel from Stockviksverken, Sweden, and microspheres sold under the PM 6545, PM 6550, PM 7220, PM 7228, Extendospheres®, Luxsil®, Q-cel® and Sphericel® brands from PQ Corp. ., Valley Forge, Pennsylvania, USA.

The cleaning compositions of the present invention will preferably be formulated so that during use in an aqueous medium, the pH of the water is between about 6.5 and about 11, or even between about 7.5 and 10.5. Liquid dishwashing compositions may have a pH between about 6.8 and about 9.0. Laundry products typically have a pH of from about 9 to about 11. Methods for controlling pH within the recommended range of use include the use of buffers, alkalis, acids, etc. and are well known to specialists in this field.

Supporting materials

Although not essential for the purposes of the present invention, the following is a non-limiting list of excipients that are suitable for use in the compositions of the present invention and may, if desired, be included in some embodiments of the invention, for example to facilitate or enhance the cleaning effect, to treat the subject cleaning the substrate or to change the aesthetic component of the cleaning composition, as is the case with fragrances, dyes, coloring agents, etc. The exact nature of such additional components and their levels of content will depend on the physical form of the composition and the nature of the cleaning operation in which they are used. Suitable auxiliary materials include, but are not limited to, surfactants, major components, chelating agents, color transfer inhibitors, dispersants, enzymes and enzyme stabilizers, catalytic materials, bleaching activators, hydrogen peroxide, hydrogen peroxide sources, preformed peracids , polymer dispersants, anti-redeposition agents for removing mineral soil contaminants, brighteners, defoamers, dyes, perfumes and, agents for structure elasticity, fabric softeners, carriers, hydrotropes, processability additives, solvents and / or pigments. In addition to what is described below, suitable examples of other such excipients and their levels of use are given in US patent No. 5576282, 6306812 B1 and 6326348 B1, which are incorporated herein by reference.

As mentioned earlier, auxiliary ingredients are not required for the compositions of the applicant. Therefore, some embodiments of the applicant’s compositions do not contain one or more of the following auxiliary materials: surfactants, main components, chelating agents, color transfer inhibitors, dispersants, enzymes and enzyme stabilizers, catalytic materials, bleaching activators, hydrogen peroxide, peroxide sources hydrogen, pre-formed peracids, polymer dispersants that prevent the re-deposition of mineral removal agents soil contaminants, brighteners, defoamers, dyes, perfumes, agents for elasticity of the structure, fabric softeners, carriers, hydrotropes that improve the workability of additives, solvents and (or) pigments. However, when one or more auxiliary materials are present, such one or more auxiliary materials may be presented, as described in detail below.

Bleaching agents: The cleaning compositions of the present invention may contain one or more bleaching agents. Suitable bleaches other than bleach catalysts include photo bleaches, bleach activators, hydrogen peroxide, sources of hydrogen peroxide, preformed peracids, and mixtures thereof. In general, when using a bleach, the compositions of the present invention may contain from about 0.1% to about 50%, or even from about 0.1% to about 25% of the bleach, based on the weight of the cleaning composition in question.

Examples of suitable bleaches include:

(1) photobleaches, for example zinc sulfonated phthalocyanine;

(2) pre-formed peracids. Suitable preformed peracids are selected from the group consisting of percarboxylic acids and salts, perugaric acids and salts, perimidic acids and salts, peroxymonosulfuric acids and salts, for example Oxzone®, and mixtures thereof. Suitable percarboxylic acids include hydrophobic and hydrophilic peracids having the formula R- (C = O) OO-M, where R is an alkyl group, optionally branched, having, if the peracid is hydrophobic, from 6 to 14 carbon atoms, or from 8 up to 12 carbon atoms, and if the peracid is hydrophilic, less than 6 carbon atoms, or even less than 4 carbon atoms; and M is a counterion, for example, sodium, potassium or hydrogen;

(3) sources of hydrogen peroxide, for example, inorganic perhydrates, including alkali metal salts, for example sodium perborates (usually mono- or tetra-hydrates), percarbonates, persulfates, perphosphates, persilicates and mixtures thereof. In one aspect of the invention, inorganic perhydrates are selected from the group consisting of sodium salts of perborate, percarbonate, and mixtures thereof. Typically, inorganic perhydrates are used in an amount of from 0.05 to 40 wt.% Or 1 to 30 wt.% Of the total weight of the composition, and are typically included in such compositions as a crystalline solid phase, which can be coated. Suitable coatings include inorganic salts, for example silicates, carbonates or borates of alkali metals or mixtures thereof, or organic materials, for example, water-soluble or water-dispersible polymers, waxes, oils or fatty soaps; and

(4) bleaching activators having R- (C = O) -L, where R is an alkyl group, optionally branched, having, if the bleaching activator is hydrophobic, from 6 to 14 carbon atoms, or from 8 to 12 carbon atoms, and if hydrophilic bleaching activator, less than 6 carbon atoms, or even less than 4 carbon atoms; and L is a leaving group. Examples of suitable leaving groups are benzoic acid and its derivatives, in particular benzenesulfonate. Suitable whitening activators include dodecanoyloxybenzene sulfonate, decanoyloxybenzene sulfonate, decanoyloxybenzoic acid and its salts, 3,5,5-trimethylhexanoylbenzene sulfonate, tetraacetyldiamine (TAED) and nonanoyloxybenzene sulfonate (NOBS). Suitable whitening activators are also disclosed in WO 98/17767. Although any whitening activator is allowed, in one aspect of the present invention, the cleaning compositions in question may contain NOBS, TAED, or mixtures thereof.

The peracid and / or whitening activator, if any, is typically present in the composition in an amount of from about 0.1 to about 60 wt.%, From about 0.5 to about 40 wt.%, Or even from about 0.6 to about 10 wt.% based on the composition. One or more hydrophobic peracids or their precursors may be used in combination with one or more hydrophilic peracids or their precursor.

The amount of the source of hydrogen peroxide and peracid or bleach activator can be selected so that the molar ratio of available oxygen (from the source of peroxide) to peracid is from 1: 1 to 35: 1 or even from 2: 1 to 10: 1.

Surfactants: cleaning compositions in accordance with the present invention may contain a surfactant or a surfactant system, the surfactant may be selected from nonionic, anionic, cationic, ampholytic, zwitterionic, semi-polar nonionic surfactants and mixtures thereof. If present, the surfactant is usually present in an amount of from about 0.1% to about 60%, from about 1% to about 50%, or even from about 5% to about 40% by weight of the composition in question.

Main components: the cleaning compositions of the present invention may contain one or more main components or main detergent systems. When using the main component, its content in the composition in question is usually at least about 1%, from about 5% to about 60%, or even from about 10% to about 40% by weight of the composition in question.

Key components include, but are not limited to, alkali metal salts, ammonium and alkanolammonium salts of polyphosphates, alkali metal silicates, alkaline earth and alkali metal carbonates, aluminosilicate components and polycarboxylate compounds, hydroxypolycarboxylate ethers, copolymers of maleic anhydride with ethylene ether or vinyl methylene , 1,3,5-trihydroxybenzene-2,4,6-trisulfonic acid, and carboxymethyloxy succinic acid, salts of various alkali metals, ammonium and substituted ammonium salts of poly acetic acids, e.g. ethylenediaminetetraacetic acid and nitrotriacetic acid, as well as polycarboxylates such as mellitic acid, succinic acid, citric acid, hydroxy succinic acid, polymaleic acid, benzene-1,3,5-tricarboxylic acid, carboxymethyloxy succinic acid and their soluble salts.

Chelating Agents: The cleaning compositions in question may contain a chelating agent. Suitable chelating agents include chelating agents of copper, iron and (or) manganese, as well as mixtures thereof. When using a chelating agent, its content in the composition in question may be from about 0.005% to about 15%, or even from about 3.0% to about 10% by weight of the composition.

Dye Transfer Prevention Agents: The cleaning compositions in question may also include one or more dye transfer inhibiting agents. Suitable polymeric agents include, but are not limited to, polyvinyl pyrrolidone polymers, N-polyprolamine polymers, N-vinyl pyrrolidone and N-vinylimidazole copolymers, polyvinyl oxazolidones and polyvinylimidazoles, as well as mixtures thereof. When using anti-dye transfer agents, their content in the composition may be from about 0.0001% to about 10%, from about 0.01% to about 5%, or even from about 0.1% to about 3% by weight of the composition.

Gloss formers: the considered cleaning compositions of the present invention may also contain additional components that change the color intensity of the products to be cleaned, for example fluorescent brighteners. The levels of suitable fluorescent brighteners include lower limits from more than about 0.01, from about 0.05 to about 0.1 wt.% Or even from about 0.2 wt.% To an upper limit of 0.5 or even 0 75 wt.%.

Dispersing agents: the compositions of the present invention may also contain dispersing agents. Suitable water-soluble organic materials include homo- or copolymer acids or their salts, in which the polycarboxylic acid contains at least two carboxyl radicals separated from each other by no more than two carbon atoms.

Enzymes: cleaning compositions may contain one or more enzymes that provide a cleaning effect and / or tissue care benefits. Examples of suitable enzymes include, but are not limited to, hemicellulase, peroxidase, protease, cellulase, xylanase, lipase, phospholipase, esterase, cutinase, pectinase, mannanase, pectate lyase, keratinase, reductase, oxidase, phenol oxidase, lipoxygenase, pullulanases, tannases, pentosanases, malanases, β-glucanases, arabinosidases, gualuronidases, chondroitinases, laccases, amylases and mixtures thereof. The usual combination is a mixture of enzymes, which may contain, for example, a protease and a lipase in combination with amylase. If the above enzymes are present in the cleaning composition, the protein content of the above enzymes can be from about 0.00001% to about 2%, from 0.0001% to about 1%, or even from about 0.001% to about 0.5% by weight of the composition.

Enzyme Stabilizers: For use in detergents, enzymes can be stabilized by various methods. The enzymes used in the present invention can be stabilized in the presence of water-soluble sources of calcium and / or magnesium ions in the final compositions containing these ions. In the case of aqueous compositions containing a protease, a reversible protease inhibitor, for example a boron compound, can be added to further increase stability.

Catalytic metal complexes: Applicant's cleaning compositions may include catalytic metal complexes. One type of metal-containing bleaching catalysts is a catalytic system containing a transition metal cation with a specific bleaching activity, for example copper, iron, titanium, ruthenium, tungsten, molybdenum or manganese, an auxiliary metal cation with little or no bleaching activity, for example, a cation zinc or aluminum, and a binder having certain stability constants for the catalytic and auxiliary metal cations, in particular ethylenediaminetetraux hydrochloric acid, ethylenediaminetetra (methylenephosphonic) acid and their water-soluble salts. Such catalysts are described in US patent No. 4430243.

If desired, the compositions of the present invention can be catalyzed using a manganese compound. Such compounds and their levels are well known in the art and include, for example, manganese-based catalysts described in US Pat. No. 5,576,282.

Cobalt whitening catalysts are known that are suitable for the present invention and are described, for example, in US Pat. Nos. 5,597,936 and 5,595,967. Such cobalt catalysts are readily prepared by known procedures, such as, for example, US Pat. Nos. 5,579,936 and 5,595,967.

The compositions of the present invention may also include a transition metal complex with ligands such as bispidones (see WO 05/042532 A1) and / or macrocyclic rigid ligands, referred to as “MRL”. In practice - but not by limitation - the compositions and methods of the present invention can be adjusted to contain at least one part per million active MRL component in a washing aqueous medium, and, as a rule, provide from about 0.005 ppm to about 25 ppm, from about 0.05 ppm to about 10 ppm, or even from about 0.1 ppm to about 5 ppm of MRL in the washing solution.

Suitable transition metals in the whitening catalysts of the present invention include, for example, manganese, iron and chromium. Suitable MRLs include 5,12-diethyl-1,5,8,12-tetrazabicyclo- [6.6.2] hexadecane.

Suitable transition metal MRLs are readily prepared using known procedures, for example, as described in WO 00/32601 and US 6225464.

Solvents: Suitable solvents include water and other solvents such as lipophilic liquids. Examples of suitable lipophilic liquids include siloxanes, other silicones, hydrocarbons, glycol ethers, glycerol derivatives, for example glycerol esters, perforated amines, perfluorinated and hydrofluoroether solvents, low volatile non-fluorinated organic solvents, diol solvents, other environmental solvents, and mixtures thereof.

Methods for the manufacture of cleaning compositions and (or) processing compositions

The cleaning compositions of the present invention can be formulated in any suitable form and prepared by any method selected by the experimenter; non-limiting examples of such methods are given in the examples of the applicant and in US patent No. 5879584, 5691297, 5574005, 5569645, 5565422, 5516448, 5489392, 5486303, all of which are incorporated herein by reference.

Mode of application

The present invention includes a method of cleaning including a surface area or fabric. The method includes the steps of contacting the applicant's cleaning composition, in pure form or as a dilute aqueous solution, with at least a portion of a surface or fabric, and then optionally rinsing said surface or fabric. The surface or fabric may undergo a washing step prior to the indicated rinsing step. For the purposes of the present invention, washing includes, but is not limited to, wiping and mechanical agitation. As will be appreciated by one skilled in the art, the cleaning compositions of the present invention are ideally suited for washing laundry. Accordingly, the present invention includes a method of washing a fabric. This method comprises the steps in which: the fabric to be washed is contacted with said cleaning detergent solution containing at least one embodiment of a cleaning composition of the applicant, a cleaning additive of the applicant or a mixture thereof. The fabric may contain virtually any fabric capable of being washed under normal consumer conditions. The solution preferably has a pH of from about 8 to about 10.5. These compositions can be used at concentrations in solution of from about 500 ppm to about 15,000 ppm. The water temperature usually ranges from 5 ° C to 90 ° C. The water / fabric ratio is usually from about 1: 1 to about 30: 1.

Organic Catalyst and Enzyme Compatibility Test

The test below uses an alpha amylase activity test to measure the effect of an organic catalyst on an enzyme.

Equipment: UV / Vis spectrophotometer capable of measuring at 415 nm; magnetic stirrer heated to 40 ° C, 5 ml syringe with Luer nozzle and filters (Acrodisc 0.45 μm), pH meter and balance (analytical, 4 digits).

Reagents: amylase kit from Merck (Merck Eurolab, cat. No. 1.19718.0001); Trizma base (Sigma, Cat. No. T-1503 or equivalent); two-water calcium chloride (Sigma, Cat. No. C-5080 or equivalent); quaternary sodium thiosulfate (Sigma, Cat. No. S-6672 or equivalent); hydrochloric acid (VWR cat. No. JT9535-0 or equivalent); stiffness solution (STS group, 3.00 g / cm ³ or equivalent); sodium percarbonate; peracetic acid (Aldrich, cat. No. 26933-6 or equivalent); amylase enzymes: termamyl, natalase and duramyl (Novozymes, Denmark); a matrix of granular detergent that does not contain an enzyme, organic catalyst or bleaching agents.

1) Preparation of the solution:

a) TRIS test buffer. Prepare 1 liter of 0.1 M TRIS buffer, 0.5% sodium thiosulfate (w / v), 0.11% calcium chloride (w / v) at pH 8.3.

b) Control solution of detergent. Prepare 1 liter of 0.5% enzyme and bleach-free granular detergent in deionized water (w / v), which is 250 ppm H ₂ O ₂ (0.77 g percarbonate), and hardness 10 gpg (hardness 880 Ul).

c) The stock of termamyl, duralyl and natalase. 100 ml of solutions are prepared containing 0.1633 mg of active termamyl per ml of TRIS buffer, 0.1159 mg of active natalase per ml of TRIS buffer, and 0.1596 mg of active duramil per ml of TRIS buffer.

d) Stocks of organic catalyst. Prepare 500 ppm in a solution of methanol in µm.

e) Stock of peracetic acid. A solution of 3955 ppm peracetic acid in deionized water is prepared.

e) Amylase reagent. Follow the instructions of the Merck kit to prepare vials (containers) 1 and 2, use vial 3, followed by mixing vials 1 and 2 to obtain the final reagent used in the analysis of amylase activity.

2) Sample analysis:

a) Analysis of a sample containing only the enzyme: add 100 ml of a control solution of the detergent in a 150 ml measuring cup. Place the beaker on a heated stirrer and adjust the temperature to 40 ° C with stirring. Add to the glass Y μl of the enzyme supply, where Y = 612 μl of duramil, 306 μl of thermamil or 918 μl of natalase. Only the enzyme of interest is labeled. Stir the sample for 1 minute. Start the timer. After 7 min 45 sec, a sample is taken out and filtered using a 0.45 μm syringe filter (5 ml syringe). 6 μl of the filtered sample is mixed with 250 μl of amylase reagent in a cuvette and the cuvette is placed in a UV / view spectrophotometer and changes in absorption at 415 nm are observed. The time duration (t _E ) required to obtain an absorbance reading of 1.0 for each enzyme is determined to within a second. Use the obtained t _E for each enzyme in steps 2b) and 2c) shown below.

6) Sample analysis only with enzyme and peracetic acid. Step 2a) is repeated, except that after adding the enzyme, the solution is allowed to mix for 1 minute, then 127 μl of the stock of peracetic acid is added and the timer is started. Take out the sample after 7 min 45 sec as in step 2a). When the sample and reagent are mixed, the absorption at t _{E is} recorded for the corresponding enzyme. Such absorption is denoted by A _b .

c) Analysis of a sample with an enzyme, peracetic acid and an organic catalyst. Step 2a) is repeated, except that after adding the enzyme, the solution is allowed to mix for 1 minute, then a supply of 127 μl of peracetic acid and a supply of 100 μl of organic catalyst are added and the timer is started. After 7 minutes and 45 seconds, the sample was removed, as in step 2a). By mixing the sample and reagent, the absorption at t _{E is} recorded for the corresponding enzyme. Designate such an absorption as A _with .

3) Calculation of the value of the compatibility of the enzyme (ECV):

a) Calculation of ECV for each specific enzyme: Thermamyl (ECV _ter ), Duramyl (ECV _dur ) and Natalase (ECV _nat ). The ECV value for any particular enzyme is (A _c / A _b ) × 100, where A _c and A _b are the values determined in steps 2c) and 2b), respectively, for a given enzyme.

6) The ECV for the selected organic catalyst is the average of the individual ECV values for these three enzymes. Therefore, ECV = (ECV _ter + ECV _dur + ECV _nat ) / 3.

Examples

Unless otherwise indicated, materials may be obtained from Aldrich, P.O. Box 2060, Milwaukee, WI 53201, USA. In Examples 1-12, the solvent — acetonitrile — can be replaced with other solvents, including but not limited to 1,2-dichloroethane.

Example 1: Preparation of Mono [2- (3,4-dihydro-isoquinolin-2-yl) -1- (2-propylheptyloxymethyl) ethyl

Preparation of 2-propylheptyl glycidyl ester: 20 g (0.127 mol) of 2-propylheptanol (Pflatz & Bauer, Inc.) are added to a calcined round-bottomed flask with an additional 500 ml funnel filled with epichlorohydrin (15.62 g, 0.17 mol). , 172E, Aurora street, Waterburry CT, 06708, USA) and 0.20 g (0.001 mol) of tin chloride. The reaction mixture was kept under argon and heated to 90 ° C in an oil bath. Epichlorohydrin is added dropwise in a stirred solution for 60 minutes, followed by stirring at 90 ° C for 18 hours. The reaction mixture is equipped with a vacuum distillation nozzle and 1-chloro-3- (2-propylheptyloxy) propan-2-ol is distilled off at a temperature in the range of 90 ° C -> 95 ° C at 2 mm Hg. Mass = 22.1 g. 5.0 g (0.020 mol) of 1-chloro-3- (2-propylheptyloxy) propan-2-ol is dissolved in 50 ml of tetrahydrofuran and stirred at room temperature under argon. 2.52 g (0.022 mol) of potassium tert-butoxide was added to the stirred solution, and the suspension was stirred at room temperature for 18 hours. Then the mixture was evaporated to dryness, the residue was dissolved in hexane and washed with water (100 ml). The hexane phase is separated off and dried with Na ₂ SO ₄ , filtered and evaporated to dryness to give crude 2-propylheptyl glycidyl ether, which can be subsequently purified by vacuum distillation.

Preparation of mono [2- (3,4-dihydro-isoquinolin-2-yl) -1- (2-propylheptyloxymethyl) ethyl ethyl inner salt of sulfuric acid ester: in a 250 ml calcined round-bottomed three-necked flask equipped with a refrigerator and a dry inlet argon, a magnetic stirrer, a thermometer and a heating bath, add 0.38 mol of 3,4-dihydroisoquinoline obtained in accordance with Example 1 of US patent No. 5576282, 0.38 mol of glycidyl ether of 2-propylheptyl obtained as described above, 0, 38 mol of the SO ₃ -DMF complex and 500 ml of acetonitrile. The reaction mixture is heated to 80 ° C and stirred at this temperature for 72 hours. The reaction mixture was cooled to room temperature, evaporated to dryness and the residue was recrystallized from ethyl acetate and (or) ethanol to give the desired product.

Example 2: preparation of an internal salt of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (2-butyloctyloxymethyl) ethyl ester

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with 2-butyl octanol.

Example 3: preparation of an internal salt of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (2-pentylnonyloxymethyl) ethyl ester

The desired product is obtained according to Example 1, replacing 2-propylheptanol with 2-pentylnonanol (from Pfaltz & Bauer Inc., Wayerbury, CT 06708).

Example 4: preparation of an internal salt of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (2-hexyldecyloxymethyl) ethyl ester

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with 2-hexyldecanol.

Example 5: preparation of an internal salt of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (dodecyloxymethyl) ethyl ester

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with n-dodecanol.

Example 6: preparation of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (tetradecyloxymethyl) -ethyl ester internal salt

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with n-tetradecanol.

Example 7: preparation of an internal salt of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (hexadecyloxymethyl) ethyl ester

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with n-hexadecanol.

Example 8: preparation of an internal salt of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (octadecyloxymethyl) ethyl ester

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with n-octadecanol.

Example 9: preparation of an internal salt of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (isononyloxymethyl) ethyl ester

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with Isononanol Exxal 9 (from Exxon Mobile Chemical, Houston, Texas, USA).

Example 10: preparation of an internal salt of mono-2- (3.4-dihydro-isoquinolin-2-yl) -1- (isodecyloxymethyl) ethyl ester

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with isodecanol (from City Chemicals LLC, WestHeaven, Connecticut, USA).

Example 11: preparation of an internal salt of mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (1-isotridecyloxymethyl) ethyl ester

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with 3-isodecanol (from BASF Corporation, Mount Olive, New Jersey, USA).

Example 12: simultaneous preparation of an internal salt of a mono-2- (3,4-dihydro-isoquinolin-2-yl) -1- (iso-tridecyloxymethyl) ethyl ester and an internal salt of a mono-2- (3,4-dihydro -isoquinolin-2-yl) -1- (iso-pentadecyloxymethyl) -ethyl ether

The desired product is obtained in accordance with Example 1, replacing 2-propylheptanol with a mixture of isomeric tridecanols-pentadecanols (from BASF Corporation, Mount Olive, New Jersey, USA).

Example 13 The bleaching detergent compositions in the form of a granular laundry detergent are represented by the following compositions. BUT AT FROM D E F Linear alkylbenzenesulfonate twenty 22 twenty fifteen twenty twenty C ₁₂ dimethylhydrokeyethylammonium chloride 0.7 one one 0.6 0,0 0.7 AE3S 0.9 0,0 0.9 0,0 0,0 0.9 AE7 0,0 0.5 0,0 one 3 one Sodium Tripolyphosphate 23 thirty 23 17 12 23 Zeolite A 0,0 0,0 0,0 0,0 10 0,0 1.6R Silicate 7 7 7 7 7 7 Sodium carbonate fifteen fourteen fifteen eighteen fifteen fifteen Polyacrylate MW 4500 one 0,0 one one 1,5 one Carboxymethyl cellulose one one one one one one Savinase 32.89 mg / g 0.1 0,07 0.1 0.1 0.1 0.1 Natalase 8.65 mg / g 0.1 0.1 0.1 0,0 0.1 0.1 Brightener 15 0.06 0,0 0.06 0.18 0.06 0.06 Brightener 49 0.1 0.06 0.1 0,0 0.1 0.1 Diethylene triamine pentaacetic acid 0.6 0.3 0.6 0.25 0.6 0.6 MgSO ₄ one one one 0.5 one one Sodium percarbonate 0,0 5.2 0.1 0,0 0,0 0,0 Photobleach 0.0030 0.0015 0.0015 0.0020 0.0045 0.0010 Sodium Perborate Monohydrate 4.4 0,0 3.85 2.09 0.78 3.63 NOBS 1.9 0,0 1.66 1.77 0.33 0.75 TAED 0.58 1,2 0.51 0,0 0.015 0.28 Organic catalyst * 0.0185 0.0185 0.0162 0.0162 0.0111 0.0074 Sulphate / Wet up to 100% up to 100% up to 100% up to 100% up to 100% up to 100% * Organic catalyst obtained in accordance with Examples 1-12, or mixtures thereof.

Any of the above composition is used for washing fabrics at a concentration in water of 3500 ppm, 25 ° C and a water: clothing ratio of 25: 1. Typically, the pH is about 10, but can be adjusted by changing the ratio of acid to alkylbenzenesulfonate in the form of a Na salt.

Example 14 The bleaching detergent compositions in the form of a granular laundry detergent are represented by the following compositions. BUT AT FROM D Linear alkylbenzenesulfonate 8 7.1 7 6.5 AE3S 0 4.8 0 5.2 Alkyl Sulfate one 0 one 0 AE7 2.2 0 3.2 0.1 C _10-12 dimethylhydroxyethylammonium chloride 0.75 0.94 0.98 0.98 Crystalline Layered Silicate (δ-Na ₂ Si ₂ O ₅ ) 4.1 0 4.8 0 Zeolite A twenty 0 17 0 Lemon acid 3 5 3 four Sodium carbonate fifteen twenty fourteen twenty Silicate 2R (SiO ₂ : Na ₂ O in a 2: 1 ratio) 0.08 0 0.11 0 Dirt repellent agent 0.75 0.72 0.71 0.72 Acrylic Acid / Maleic Acid Copolymer 1,1 3,7 1,0 3,7 Carboxymethyl cellulose 0.15 1.4 0.2 1.4 Protease (56.00 mg of active substance / g) 0.37 0.4 0.4 0.4 Amylase (21.55 mg of active substance / g) 0.3 0.3 0.3 0.3 Lipase (11.00 mg of active substance / g) 0 0.7 0 0.7 Tetraacetylethylenediamine (TAED) 3.6 4.0 3.6 4.0 Percarbonate 13 13,2 13 13,2 Organic catalyst * 0.04 0.02 0.01 0.06 Na-salt of ethylenediamine-N, N'-disuccinic acid, (S, S-isomer) (EDDS) 0.2 0.2 0.2 0.2 Hydroxyethane diphosphonate (HEDP) 0.2 0.2 0.2 0.2 MgSO ₄ 0.42 0.42 0.42 0.42 Perfume 0.5 0.6 0.5 0.6 Foam suppressor agglomerate 0.05 0.1 0.05 0.1 Soap 0.45 0.45 0.45 0.45 Sodium sulfate 22 33 24 thirty Sulfonated Zinc Phthalocyanine 0,07 0.12 0,07 0.12 Photo bleach 0.0014 0.002 0.0014 0.001 Blotches 0,03 0.05 0,03 0.05 Water and stuff up to 100% up to 100% up to 100% up to 100% * Organic catalyst obtained in accordance with Examples 1-12, or mixtures thereof.

Any of the above composition is used for washing fabrics at a concentration in water of 10,000 ppm, 20-90 ° C and a ratio of water: clothes 5: 1. Typically, the pH is about 10, but can be adjusted by changing the ratio of acid to alkylbenzenesulfonate in the form of a Na salt.

Example 15 The bleaching detergent compositions in the form of a granular laundry detergent are represented by the following compositions.

Linear alkylbenzenesulfonate 19.0 15.0 20,0 19.0 18.0 17.5 Alkyl Sulfate 1,1 1,0 0.8 1,0 1,1 1,2 AE3S 0.3 0.2 0,0 0.1 0.3 0.5 Partially neutralized polyacrylic acid 6.0 5.5 7.5 7.0 5.8 6.0 Sodium xylene sulfonate * 1,5 1.9 2.0 1.7 1,5 1,0 PEG 4000 0.3 0.25 0.35 0.15 0.2 0.10 Brightener 49 0 0 0.32 0.04 0.04 0.16 Brightener 15 0 0 0.68 0.08 0.08 0.32 Moisture 2,50 2.00 2.90 2.20 2.40 1.80 Sodium carbonate 20,0 17.5 21.0 20,2 19.0 18.0 Sodium sulfate 0.20 0.30 0.50 0.30 0.45 0.10 Sodium silicate 0.25 0.25 0.55 0.30 0.25 0.10 Layered silicate 2.7 3.0 2.2 3,7 1,5 1,0 Zeolite A 11.0 11.0 12.5 10,2 9.5 8.0 Protease 0.20 0.50 1,0 0.15 0.40 0,0 Silicone foam suppressor 0.40 0.35 1.00 0.60 0.50 0.00 Lumpy Sulphate 21.5 23.0 21.0 21.0 20,0 18.5 Amine reaction product containing δ-Damascon **** 0.40 0.25 0.10 0.35 0.60 0.00 Perfume 0.10 0.30 0.20 0.20 0.40 0.50 Sodium percarbonate 2,8 4,5 2.00 4.7 7.4 10.0 Traditional Activator (NOBS) 2.10 3,7 1.00 3.0 5,0 10.0 Organic catalyst ** 0.005 0.10 1.00 0.25 0.05 0.05 Subcendent *** 0.50 0.20 1.00 0.30 0.10 0.00 Filler up to 100% Up to 100% up to 100% up to 100% up to 100% up to 100% * Other hydrotropes, such as toluenesulfonate, may also be used. ** Organic catalyst obtained in accordance with Examples 1-12, or mixtures thereof. *** Such as Ultramarine Blue or Azo-CM-Cellulose (Megazyme, Bray, Co. Wicklo Ireland). **** Received in accordance with WO 00/02991.

Any of the above composition is used for washing fabrics at a concentration in water of 500-1500 ppm, 5-25 ° C and a ratio of water: clothes 15: 1-25: 1. Typically, the pH is about 9.5-10, but can be adjusted by changing the ratio of acid to alkylbenzenesulfonate in the form of a Na salt.

Example 16

The organic catalysts listed below were tested in accordance with the compatibility test of the organic catalyst of the present invention and the enzyme using: [peracetic acid] = 5.0 ppm; [organic catalyst] = 0.5 ppm, to obtain the following results.

Position* Catalyst Group R ¹ Enzyme Compatibility ECV _ter ECV _dur ECV _nat ECV one Tert-butyl 51 86 58 65 2 2-ethylhexyl 54 90 57 67 3 2-propylheptyl 98 101 99 99 four 2-butyl octyl 101 101 102 101 5 n-C ₁₂ H ₁₄ 102 one hundred one hundred 101 6 Isononil 86 96 88 90 7 Isodecyl 98 97 96 97 8 Isotridecyl 99 one hundred 101 one hundred * Positions 1 and 2 represent, respectively, branched C ₄ and C ₈ alkyl fragments that are not included in formula 1.

It will be apparent to those skilled in the art that the described and illustrated particular embodiments of the present invention may be modified and modified without departing from the spirit and scope of the present invention. Therefore, all such changes and modifications falling within the scope of this invention are covered by the appended claims.

Claims (15)

1. A cleaning composition containing:
a) an organic catalyst selected from the group consisting of organic catalysts having the following formulas:
(i)

(ii)

(iii) and mixtures thereof;
where each R ¹ independently is a branched alkyl group selected from the group consisting of 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, isodecyl, isotridecyl and isopentadecyl, or a linear alkyl group containing from 11 to 18 carbon atoms; and
b) one or more accessory ingredients. 2. The cleaning composition according to claim 1, characterized in that each R ^{1 is} independently selected from the group consisting of 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, isodecyl, isotridecyl and isopentadecyl. 3. The cleaning composition according to claim 1, characterized in that it contains an organic catalyst having the following formula:

where each R ^{1 is} independently selected from the group consisting of 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, isodecyl, isotridecyl and isopentadecyl. 4. A cleaning composition according to claim 3, characterized in that R ^{1 is} independently selected from the group consisting of 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, isodecyl, isotridecyl and isopentadecyl. 5. The cleaning composition according to claim 1, characterized in that it contains an organic catalyst having the following formula:

where each R ^{1 is} independently selected from the group consisting of 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, isodecyl, isotridecyl and isopentadecyl. 6. The cleaning composition according to claim 5, characterized in that R ^{1 is} independently selected from the group consisting of 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, isodecyl, isotridecyl and isopentadecyl. 7. The cleaning composition according to claim 1, characterized in that at least one of the one or more auxiliary ingredients mentioned is selected from activated sources of peroxygen, enzyme, surfactant, and mixtures thereof. 8. The cleaning composition according to claim 3, characterized in that at least one of the one or more auxiliary ingredients mentioned is selected from activated sources of peroxygen, enzyme, surfactant and mixtures thereof. 9. The cleaning composition according to claim 5, characterized in that at least one of the aforementioned one or more auxiliary ingredients is selected from activated sources of peroxygen, enzyme, surfactant and mixtures thereof. 10. The cleaning composition according to claim 1, characterized in that it contains the following auxiliary ingredients: an activated source of peroxygen, an enzyme and a surfactant. 11. The cleaning composition according to claim 3, characterized in that it contains the following auxiliary ingredients: an activated source of peroxygen, an enzyme and a surfactant. 12. The cleaning composition according to claim 5, characterized in that it contains the following auxiliary ingredients: an activated source of peroxygen, an enzyme and a surfactant. 13. The cleaning composition according to claim 1, characterized in that R ^{1 is} selected from the group consisting of 2-butyl octyl, 2-pentylnonyl, 2-hexyldecyl, isotridecyl and isopentadecyl, and said composition contains the following auxiliary ingredients: an activated source of peroxygen, an enzyme and surfactant. 14. The cleaning composition according to claim 1, characterized in that it contains an organic catalyst having an compatibility value with an enzyme of 70 or more, and one or more auxiliary compounds. 15. The cleaning composition according to 14, characterized in that it contains an organic catalyst having an enzyme compatibility value of 80 or more, and said composition contains the following auxiliary ingredients: an activated source of peroxygen, an enzyme and a surfactant.