RU2272637C2 - Method for prophylaxis of caries - Google Patents

Abstract

FIELD: medicine, stomatology.

SUBSTANCE: invention relates to a method for prophylaxis of caries. Method involves every day mouth cavity gargling with natural mineral water with the fluoride content above 1.2 mg/ml during teeth cleansing and after cleansing for 1 min, not less, by course for 7-10 days. In partial case method involves using natural mineral water "Svetloyarskaya" with the fluoride content 1.7 mg/l for prophylaxis of caries in children living in regions with reduced fluoride content in drinking water. Method provides effective prophylaxis of caries excluding toxic effect of trace elements on body presenting in mineral water.

EFFECT: enhanced effectiveness of prophylaxis.

3 cl, 3 tbl, 1 ex

Description

The present invention relates to medicine, namely to dentistry, and can be used to prevent caries. The use of this method is especially recommended for children living in areas with a low fluorine content in drinking water.

A high percentage of diseases of the oral organs in children, especially dental caries, is a serious epidemiological problem. According to E. M. Kuzmina (2001), it was found that 22% of six-year-old children suffer from decay of permanent teeth. Carrying out only therapeutic measures is not a cardinal solution to the problem (E.V. Borovsky, V.K. Leontyev, 1991). Therefore, the most important role should be assigned to the development and implementation of a system of preventive measures. A mandatory tool for the prevention of caries is rational hygiene and sanitation of the oral cavity.

However, these measures are not enough, especially for those living in areas with low levels of fluoride and calcium in drinking water, and therefore new methods of caries prevention are constantly being developed. A known method for the prevention of caries, including the intake of oral tablets of sodium fluoride at a rate of 1.5 mg per day for 3 days with a course after 6 months (Ru C1 2014078. Method for the prevention of caries).

The disadvantage of this method is that the drug is taken orally, and therefore there is a systemic effect of fluorine on the body, which does not exclude the possibility of toxic effects of fluoride, especially if the individual dosage is incorrectly calculated in young children. The inconvenience is the need to dissolve the tablets.

There is a method of individual prevention of caries with an enamel sealing liquid with the treatment of hard tooth tissues with this liquid 1-4 times a year with an interval of 3 months (Ru C1 2210375. Method for individual prevention of caries with an enamel sealing liquid). The disadvantages of the method are inaccessibility and high cost.

Closest to the technical nature of the present invention is a method for the prevention of caries, including the use of mineral water. In the literature, we found an article by N.N. Garazh, I.M. Fleishmakher "On the influence of the Kislovodsk narzan on the frequency and intensity of dental caries and the state of periodontal disease" (journal "Dentistry", No. 1, 1996, pp. 33-36) . Kislovodsk Narzan is a carbon dioxide-carbonate-sulphate magnesium-sodium water of complex composition, pH from 6.2 to 6.8. The authors examined patients aged 20-59 years, using narzan for many years for drinking. Analysis of the results of the examination showed that Kislovodsk narzan can be considered a cariesstatic agent that helps to reduce tooth decay caries.

The disadvantage of this method is the prolonged use of mineral water for drinking. In addition, we did not find information about the fluorine content in this mineral water, and this microelement is important for the prevention of dental caries, and this microelement is important for the prevention of dental caries, especially in children living in areas with low fluoride content in drinking water. When using mineral water for drinking, a systemic effect of microelements on the patient’s body occurs, which, as mentioned above, does not exclude the possibility of toxic effects.

The objective of the invention is the development of an effective, short and affordable way to prevent caries, eliminating the possibility of toxic effects on the body of trace elements (by eliminating prolonged use inside).

The problem in the method of caries prevention, including the use of mineral water, is achieved by the fact that natural mineral water with a fluorine content of more than 1.2 mg / l is daily rinsed during brushing and for at least 1 min after brushing, the course is not less than 7-10 minutes; it is used in children living in areas with low fluoride in drinking water; use natural mineral water "Svetloyarskaya" with a fluorine content of 1.7 mg / L.

The author of this application for the first time showed that the local use of mineral water with a high fluorine content is much more effective than the use of fluoride and mineral water "Narzan" inside, and also more effective than the local use of fluoride-containing toothpastes. This is due to the fact that when using drugs inside, first of all, their systemic effect on the body occurs, and not the formation of fluorapatite in tooth enamel. The use of fluoride-containing toothpastes is less effective due to the fact that the paste is rinsed out quickly when rinsing the mouth with water during brushing, which also does not cause the formation of a sufficient amount of fluorapatite in the tooth enamel.

The elimination of the need to use fluorine or mineral water preparations for a long time inside eliminates the possibility of toxic effects on the body with an improperly selected individual dose of trace elements. A new and unexpected effect of the local application of mineral water according to the proposed method was the increase in the nonspecific resistance of the body, established by the author of this application, manifested in a significant increase in the activity of oral lysozyme already a week after the application of the proposed method and continued to grow for at least a month after completion of the weekly course of local application of mineral water with a high content of fluoride.

The listed effects established by the author of this application are the new technical result of the proposed method.

During the development of the proposed method, before the implementation of the complex of preventive measures, an examination of the state of the oral cavity in six-year-old children was conducted. During the initial examination, all children must have had professional oral hygiene. After that, the children were taught the rules of good hygiene and oral sanitation was carried out. Local application of mineral water according to the proposed method began 6 months later after the ambassador of training in rational hygiene and oral sanitation.

All children were prescribed daily rinses of the oral cavity during each toothbrushing (instead of ordinary water) and for at least 1 minute after brushing their teeth with Svetloyarskaya natural mineral water produced by the Sormovsky Vodka and Vodka Factory in Nizhny Novgorod. The course of use is at least 7-10 days (during the development of the method, children used local rinses for 7 days). The upper limit of the duration of use is not limited.

Mineral water "Svetloyarskaya" is a low-mineralized, sulfate magnesium-calcium composition, with a slightly alkaline reaction of the medium - pH 7.6, calcium content 505 mg / l (norm 350-600 mg / l), fluorine 1.7 mg / l (norm 1 mg / l, optimum 0.8-1.2 mg / l).

The condition of the oral cavity was analyzed before the application of the proposed method, immediately after the end of the course (ie, the day after the end of the 7-day daily use of Svetloyarskaya mineral water according to the proposed method) and a month after the end of the course. In this case, the content of phosphorus and calcium in the oral fluid was determined, as well as the activity of the lysozyme in the oral fluid. The results are presented below in tables 1-3.

Against the background of the ongoing preventive measures, a significant increase in the activity of oral lysozyme is observed already a week after the preventive measures. This indicates that rinsing the oral cavity with this mineral water helps maintain the balance of one of the most sensitive biotopes (oral cavity) under adverse conditions.

Table 3
The calcium content in the oral fluid in children before and after preventive measures Group of children Calcium Content (mmol / L) Before applying the proposed method 1 month after rinsing the oral cavity according to the proposed method n = 10 0.729 ± 0.36 * 0.519 ± 0.16 * * - p <0.05, the differences are statistically significant, F is the Fisher test.

As follows from the tables, the phosphorus content in the oral fluid has increased. Excess phosphate interferes with the process of crystallization and demineralization of tooth hard tissues, helping to maintain physiological balance. In this case, a decrease in the calcium content in the oral fluid while using natural mineral water with a high fluorine content does not look paradoxical. Activation of the process of remineralization of hard tissues of the tooth enhances the diffusion of calcium into the tooth enamel, which is expressed by a decrease in the content of this trace element in the composition of the oral fluid. When fluorine-containing mineral water is used, an isomorphic substitution process occurs in hydroxyapatite and the formation of hydroxyfluoroapatite, which temporarily reduces the need for calcium.

An example of a specific implementation of the method is given in the form of an extract from the card of the dental examination of the patient.

Patient Sh., 6 years old.

After sanitation of the oral cavity and training in rational oral hygiene, before carrying out preventive measures according to the proposed method, it was determined in the oral fluid: lysozyme activity of 22%, calcium content of 0.63 mmol / l, phosphorus content of 2.74 mmol / l. Then, for 7 days, the patient daily, while brushing his teeth and after brushing for at least 1 min, rinsed the oral cavity with Svetloyarskaya natural mineral water with a fluorine content of 1.7 mg / l under the supervision of a dentist. Immediately after the completion of the 7-day course, an analysis of the composition of the oral fluid was again carried out: lysozyme activity 34%, calcium content 0.61 mmol / l, phosphorus content 4.92 mmol / l. 1 month after a weekly course of using mineral water, a third analysis of the composition of the oral fluid was carried out: lysozyme activity of 59%, calcium content of 0.48 mmol / l, phosphorus content of 5.56 mmol / l. The biochemical parameters of the oral fluid (calcium and phosphorus content) were determined in the biochemical laboratory of the Nizhny Novgorod Pediatric Institute of Gastroenterology, the activity of the oral fluid lysozyme was determined on the basis of the Department of Microbiology and Immunology of the Nizhny Novgorod State Medical Academy.

Claims (3)

1. A method for the prevention of caries, including the use of mineral water, characterized in that natural mineral water with a fluorine content of more than 1.2 mg / l daily rinses the mouth during brushing and for at least 1 min after brushing, with a course of at least 7-10 days. 2. The method according to claim 1, characterized in that it is used in children living in areas with a low fluorine content in drinking water. 3. The method according to claim 1, characterized in that they use natural mineral water "Svetloyarskaya" with a fluorine content of 1.7 mg / ml