RU2262867C2 - Food biologically active additive for improving human reproduction (variants) - Google Patents

Abstract

FIELD: food industry.

SUBSTANCE: the present innovation deals with balanced nutrition in children of early age and their parents. The suggested food BAA contains hydrolyzate of serumal protein, BAA "Iodine-casein", nucleotides, arginine, cysteine, tyrosine, tryptophan, carnitine, taurine, lecithin, inositol, lysozyme, powder of Jerusalem artichoke's tubers, powder of hen egg's shell or hydroxyapatite, vitamin D₃, lipoic acid, BAA "Vetoron-TK", BAA "Selenium EC", BAA "Hemobin" and lactic fat "Betapol 45". Moreover, components should be taken at the quantity corresponding to 50-100% of physiological body requirement in each nutrient. Additionally, two variants for obtaining food BAA are, also, presented. The innovation enables to obtain BAA, especially, out of food components balanced so that it enables to maximally digest them by the body and stimulate immunity, being of bifidogenic effect due to development and keeping own functional intestinal microflora.

EFFECT: higher efficiency of application.

3 cl, 3 ex

Description

The invention relates to the food industry, in particular to a balanced diet of young children and their parents.

At present, adapted mixtures are being created for feeding children, approaching, in terms of basic characteristics, to breast milk. The ratios of casein to whey proteins, individual minerals among themselves, minerals and vitamins, the acidity of the nutrient mixture depending on the age of the child are taken into account / 1 /. The so-called “casein formulas” are less adapted: “Semilak” (USA), “Unfavored” (Switzerland). They are made from dried cow's milk, the main protein component of which is casein, and without the addition of whey. In this they differ from the protein composition of human milk and are used with great care. Symptoms of intolerance to cow's milk protein are diarrhea with an admixture of blood, which can be very difficult and not stop until the dairy products are completely eliminated. In many children, diarrhea is accompanied by allergic symptoms - rash, eczema / 2 /. It was revealed that the ability of a future mother to feed her baby also depends on her intrauterine development, which determines the metabolism of an adult female body / 3 /.

The technical result is to obtain dietary supplements mainly from food components balanced in such a way that allows them to be absorbed by the body as much as possible, stimulating the immune system, having a bifidogenic effect due to the development and maintenance of their own functional intestinal microflora and with satisfactory organoleptic properties.

The technical result is achieved in that dietary supplements for children from six months of age (the first embodiment of the invention) contain whey protein hydrolyzate, nucleotides, arginine, cysteine, tyrosine, tryptophan, carnitine, inositol, taurine, Jerusalem artichoke tubers powder, chicken egg yolk powder, pumpkin seed powder, beta-lactose, hydroxyapatite or eggshell powder, dietary supplement “Iodcasein”, lipoic acid, lysozyme enzyme, vitamin Dz, lecithin, milk fat “Betapol 45”, dietary supplement “Vetoron TK”, dietary supplement “SelenES”, dietary supplement "Hemobin". In this case, the components are taken in an amount corresponding to 50-100% of the physiological needs of the (child) body in each nutrient. As part of a dietary supplement, an option for a child, the components of milk are significantly limited, minerals in an inorganic form are excluded, emulsifiers (like soya lecithin in Nestozhen) and other components of soya (as in breast milk substitutes: Heinz, MdmilSoya, Peptidi Tutteli "," Nestle Alsoy "and" Nan Soya)) because the pathological effects of the ingredients of this plant on the children's body (and not only allergic ones) are revealed / 4, 5, 15 /.

Good nutrition is especially important at reproductive age. Here, in addition to objective indicators of health, it is important, from the point of view of female psychology (and male, if not more), subjective indicators of attractiveness - the degree of completeness, the condition of the skin, hair and teeth. The nutrition of many pregnant and lactating women is often unsatisfactory. Hence the defective composition of breast milk, a short period of lactation, or even its absence. The qualitative composition of food during pregnancy is extremely important for the mother and the fetus, as it has a direct effect on embryo development and upcoming lactation. It is necessary to compensate for any specific types of nutritional deficiencies, for example, those associated with a reduced content of micro and macro elements / 6, 7 /, vitamins in food products, with their low digestibility or physiologically increased need. In addition to the above, the female version of dietary supplements contains the necessary substances that are present in breast milk and contribute to the utilization of fats as an energy source. Their insufficiency is explained by the increased need for them in women during pregnancy and breastfeeding. These nutrients improve the functioning of the immune system, moreover, they are safe, well tolerated and taste good, which is important for the food component. It is known that thyroid hormones especially exert their influence in certain periods of time of individual development of a person. Inadequate levels of the hormone can lead to devastating consequences of the developing brain of the embryo, especially during the 1st trimester of pregnancy. So, pregnant women with a lack of thyroids gave birth to children with reduced intelligence 4 times more often than those with normal levels of the hormone / 8 /. Thyroid deficiency often occurs as a result of iodine deficiency / 9 /. The latter is included in bioavailable form.

In the second embodiment, the technical result is achieved in that the dietary supplement for women of reproductive age (planning to conceive, pregnant and lactating) contains wheat germ powder, Jerusalem artichoke tubers powder, table beet juice powder, pumpkin seed powder, flax seed powder, parsley juice powder , chicken egg yolk powder, lemon juice powder, selenium iodized yeast autolysate powder, tomato flakes, hydroxyapatite or egg shell powder, royal jelly, beta-lactose, arginine n, carnitine, lysine, inositol, folic acid, dietary supplement Hemobin, lecithin and lipoic acid. In this case, the components are also taken in an amount corresponding to 50-100% of the physiological needs of the (female) body in each nutrient.

The environmental situation, stressful factors, refined and unbalanced food on the most important elements dramatically reduce the quality of life of a modern man, in particular sexual. According to a reputable Massachusetts Male Aging Study, half of men over 40 have erectile dysfunction. Nitric oxide (NO), the synthesis of which is induced from the amino acid arginine, was found to be the main peripheral pro-erectile factor. It is the only natural NO precursor in the body. It was found that in men reactive blood supply to the genitals, as well as in women, is an NO-dependent process. And since this is an important part of sexual arousal, an increased concentration of NO significantly increases the degree of sexual arousal and the brightness of an orgasm. In this way, manifestations of impotence in men and frigidity in women can be removed. The hemodynamic activity of arginine has been demonstrated by numerous clinical studies. The effectiveness of the amino acids taken by the tablet is also confirmed in various cardiovascular diseases that limit the sexual behavior of both men and women / 10 /.

Arginine is a common component of the presented dietary supplement and the male formula "Veromax" ("Cobra International", USA). However, instead of the exotic components of the latter - plant extracts of Ginkgo biloba, Zizifus jube, Korean ginseng, dwarf palm and Kudzu - the dietary supplements presented include no less effective, but traditional for the digestion of Russian men, plant components. Similarly to Veromax, the male formula of Enrich International, also produced in the USA, also contains extracts of exotic fruits of the serenoa tree, amer aphrodisiac, wild sweet potato, Korean and Brazilian ginseng. By the way, it is no accident that a slightly different effect of these dietary supplements on American and Russian men was noted.

In a third embodiment of the invention, the technical result is achieved in that a dietary supplement for men of reproductive age contains wheat germ powder, Jerusalem artichoke tubers powder, table beet juice powder, pumpkin seed powder, flax seed powder, Chinese schisandra seed powder, parsley juice powder, parsley powder chicken egg yolk, lemon juice powder, tomato flakes, hydroxyapatite or egg shell powder, arginine, carnitine, lysine, lipoic acid, SelenES dietary supplement, Yodkasein dietary supplement, Vetoron TK dietary supplement. In this case, the components are also taken in an amount corresponding to 50-100% of the physiological needs of the (male) body in each nutrient.

The most promising direction in the prevention of dysbacteriosis is the introduction into the diet as prebiotics of lactose and fructooligosaccharides, selectively "feeding" bifidobacteria and lactobacilli of the gastrointestinal tract. For example, bacteria break down the inulin polymer, which is part of the food components of the dietary supplement, to fructose. Thus fed, normoflora suppresses the reproduction of pathogenic intestinal microflora by competitive displacement / 11, 12 /, producing nicosine, nisin, colicins, which have a protective effect against breast cancer. On the other hand, fructooligosaccharides reduce the level of lipids in the blood, in particular cholesterol, which introduces another health factor / 13 /. In addition, bifidobacteria are effective in detoxifying carcinogens and mutagens coming from outside, including with food / 14 /.

In addition to the general properties indicated in the technical result, each option of dietary supplement has additional properties that are inherent for each option directly. In particular, the variation of dietary supplements, designed to feed children from six months of age, has the following properties:

- supplies substrates for the synthesis of species-specific protein and nucleic acids (amino acids, whey protein hydrolyzate and nucleotides);

- promotes bone growth (calcium and phosphorus finely divided hydroxyapatite, vitamin D ₃ ), prevents rickets;

- supplies easily digestible iron (dietary supplement "Hemobin"), stopping the characteristic iron deficiency anemia typical for half a year;

- promotes the colonization of the gastrointestinal tract with beneficial microflora (nucleotides, milk sugar, Jerusalem artichoke inulin) and the suppression of pathogenic microflora of the body (lysozyme);

- creates a potential basis for the development and strengthening of the child's body in terms of future reproduction / 3 /.

Food supplements intended for women of reproductive age, has the following properties:

- stimulates sexual activity (arginine, folic acid, vitamin E of wheat germ);

- supplies calcium and phosphorus deficient hydroxyapatite deficient during pregnancy and lactation, easily digestible iron of animal origin (Hemobin dietary supplement), and iodine in bioorganic form;

- has a lactogonous effect (royal jelly);

- supports energy tone (carnitine, vitamins, iron);

- has a protective effect on breast tumors (highly effective antioxidant lycopene tomatoes).

Food supplements intended for men of reproductive age, has the following properties:

- stimulates sexual activity (arginine, Chinese magnolia vine seeds, pumpkin seed zinc, root greens, selenium, carnitine);

- has a protective effect on prostate neoplasms (tomato lycopene, pumpkin seed zinc).

The claimed dietary supplements for food are characterized by the following examples embodying the invention.

Example No. 1.

For the manufacture of dietary supplements (as food for children from six months of age) the following are used (in weight%): whey protein hydrolyzate - 45, nucleotides - 0.95, arginine - 0.3, cysteine - 0.3, tyrosine - 0.3, tryptophan - 0.3, carnitine - 0.5, inositol - 0.3, taurine - 0.4, Jerusalem artichoke tubers powder - 10, chicken egg yolk powder - 5, pumpkin seed powder - 14.5, beta-lactose - 5, hydroxyapatite or chicken egg shell powder - 5, dietary supplement "Iodcasein" - 0.4, lipoic acid 0.25, lysozyme enzyme 0.25, vitamin D ₃ 0.25, lecithin 0.25, Betapol 45 milk fat 0.25, Vetoron TK dietary supplement 0.5, Sel dietary supplement enES "- 5, dietary supplement" Hemobin "- 5.

The quantitative composition of the components is selected based on 50-100% of the daily needs of the child's body in each nutrient. The presented dietary supplement is balanced by the main nutrients that make up breast milk, contributes to immune and anti-allergenic activity. The mixture is packaged in vacuum portioned bags for a single feeding of the child. All components are easily digestible and hypoallergenic.

Example No. 2.

For the manufacture of food supplements (for women of reproductive age), the following are used (in weight%): wheat germ powder - 10, Jerusalem artichoke tubers powder - 15, table beet juice powder - 13, pumpkin seed powder - 15, flax seed powder - 7, parsley juice powder - 3, chicken egg yolk powder - 6, lemon juice powder - 3, autolysate powder of selenium iodized yeast - 5, tomato flakes - 9, hydroxyapatite or egg shell powder - 3, royal jelly - 0.6, beta-lactose - 2.65, arginine - 0.05, carnitine - 1, lysine - 0.2, inositol - 0.3, folic acid ota - 0.3, BAD "Gemobin" - 4, lecithin - 2, lipoic acid - 0.2.

The quantitative composition of the components is selected based on 50-100% of the daily needs of the female body in each nutrient. All components are easily digestible and hypoallergenic.

The mixture is tabletted and then sealed in blisters.

Example No. 3.

For the manufacture of food supplements variations (for men of reproductive age) the following are used (in weight%):

wheat germ powder - 12, Jerusalem artichoke tubers powder - 11.5, table beet juice powder - 12.5, pumpkin seed powder - 12.5, flax seed powder - 7, Chinese schisandra seed powder - 9, parsley juice powder -9, chicken egg yolk powder -4 , lemon juice powder - 12.5, tomato flakes - 6, hydroxyapatite or eggshell powder - 1, arginine - 0.25, carnitine - 0.25, lysine - 0.25, lipoic acid - 0.75, dietary supplement "SelenES" - 0.5, dietary supplement "Iodcasein" - 0.5 , Dietary supplement "Vetoron TK" - 0.5.

The quantitative composition of the components is selected based on 50-100% of the daily needs of the male body in each nutrient. All components are easily digestible and hypoallergenic.

The mixture is tabletted and then sealed in blisters.

References

1. Milk from a bottle. Druzhinina A., female “Family Doctor”, No. 4, 2000, p. 57-58.

2. Adaptive mixtures based on goat's milk in the prevention and treatment of intolerance to cow's milk proteins. Horse I.Ya. (Institute of Nutrition RAMS), g. "Children's Doctor", 2001, No. 1, pp. 59-60.

3. The mainouriched baby and infant. Barker D. Brit. Med. Bull., 2001, 60, 69-88.

4. Tragedy and Hype, The III Internet Soy Symposium. Nexus Magazine, 2000, v. 7, 3.

5. Perinatal dietary sapplemantation with a soy lecithin preparation: effects on development of central catecholaminergis neurotransmitter systems. Bell J.M. et all. Brain Res. Bull. 1986, 17 (2): 189-195.

6. Anemic syndrome in clinical practice. Vorobev P.A., 2001, p. 37.

7. "Osteogenon" in the Vidal reference book "Drugs of Russia". M., 2001, B-439.

8. The thyroidin pregnancy: a European perspective. Glinder D., In "Thyroid today", Oppenheimer (ed). 1997, 18: 1-11.

9. Dietary supplements of Dr. Atkins. Atkins R.M., "RIPOL CLASSIC", 1999.

10. A new approach to the correction of genital disorders. Gostry A.V. "Medicina altera". 2001, No. 11, pp. 15-18.

11. The use of flour Jerusalem artichoke (Jerusalem artichoke - ed.) For dysbiosis in children. Lisitsina I. and Toropova T. II int. conf. "VITAMAX Corporation systemic health products and their use for preventive purposes in the most common diseases." M., 1999, p. 33-35.

12. Materials. meeting-seminar "Nutrition for young children", N. Kochnev, O. Prokopieva Irkutsk, 1994, p. 41-43.

13. Innovative food products based on inulin and oligofructose. Ostend P.V., Sat. doc. 2nd International Forum "Food Ingredients in Food Products of the XXI Century", Moscow, November 28-30, 2001, p.23-31.

14. The effectiveness of the use of live concentrated lactobacilli and bifidobacteria. Rimarchuk T., f. "Medicina altera", 2001, 4, pp. 21-24.

15. Breast and soy-formula, feedings in early infancy and the prevalence ofantoummune thyroid disease in children. Fort P. et all. J. Am. Coll. Nutr. 1990, 9 (2): 164-67.

Claims (3)

1. A dietary supplement containing whey protein hydrolyzate, dietary supplement “Iodine-casein”, nucleotides, arginine, cysteine, tyrosine, tryptophan, carnitine, taurine, lecithin, inositol, lysozyme, chicken yolk powder, pumpkin seed powder, beta-lactose, Jerusalem artichoke tubers powder, chicken egg or hydroxyapatite shell powder, vitamin D ₃ , lipoic acid, Vetoron-TK dietary supplement, SelenES dietary supplement, Gemobin dietary supplement and Betapol 45 milk fat, while the components are taken in an amount corresponding to 50-100% of the physiological needs of the body in each nutrient. 2. A dietary supplement containing wheat germ powder, Jerusalem artichoke tubers powder, table beet juice powder, Se- and I-yeast autolysate powder, pumpkin seed powder, flax seed powder, celery or parsley juice powder, chicken yolk powder, egg powder shell or hydroxyapatite, lemon juice powder, royal jelly, beta-lactose, carnitine, lecithin, tomato flakes, inosine, Hemobin dietary supplement, arginine, lysine, lipoic acid, folic acid, while the components are taken in an amount corresponding to 50- 100% physiological otrebnosti organism in each nutrient. 3. A dietary supplement containing wheat germ powder, pumpkin seed powder, celery or parsley juice powder, egg shell or hydroxyapatite powder, lemon juice powder, Chinese schisandra seed powder, Jerusalem artichoke tubers powder, table beet juice powder, chicken yolk powder, chicken yolk powder flax seeds, tomato flakes, carnitine, dietary supplement "Iodine-casein", dietary supplement "SelenES", arginine, lysine, lipoic acid, dietary supplement "SelenES", while the components are taken in an amount corresponding to 50-100% of the physiological needs of the body in each chickpea iente.