RU2262296C2 - Device for setting diagnosis using r. voll's method - Google Patents

Abstract

FIELD: medical engineering.

SUBSTANCE: device has a measuring and two indifferent electrodes, switchboard, three amplifiers, three memory units, three subtraction units, two calibrated resistors, two division units, flip-flop unit, controllable potential divider, potential divider, two recorders and reference voltage source. The second device embodiment has a measuring and two indifferent electrodes, three switchboards, three amplifiers, three memory units, three subtraction units, two calibrated resistors, division unit, two flip-flop units, controllable potential divider, potential divider, two recorders and reference voltage source. The third device embodiment has a measuring and two indifferent electrodes, three switchboards, two amplifiers, four memory units, subtraction unit, two calibrated resistors, two flip-flop units, two controllable potential dividers, potential divider, two recorders and reference voltage source, voltage unit selector, two electronic keys, three coincidence circuits and comparator unit.

EFFECT: high accuracy of measurement transformations; high reliability of recorded data parameters.

12 cl, 3 dwg, 3 tbl

Description

The invention relates to medical information-measuring equipment, namely, devices for acquiring information during diagnostic studies on the parameters of the skin at acupuncture points used to implement the medical diagnostic method of R. Voll, widely represented in modern medicine.

Devices for diagnosis according to the method of R. Voll should provide control of the energy state of the body, carried out by measuring the electrical parameters of the selected areas of the skin surface (diagnostic acupuncture points) in the values of the conventional units of "conductivity" (Werner F. Fundamentals of electroacupuncture - M .: IMEDIS, 1993. - 184 p .; Kramer F. Textbook on electro-puncture, vol. I. - M .: IMEDIS, 1995. - 189 p.). In this case, the energy state of the body is characterized by the degree of neutralization of the measuring electric current passed through the skin, determined by the electric potentials E of the body between the electrodes of the device, arising to compensate for the electric current at precisely dosed values.

At the same time, the reliability of the diagnostic tests performed by the R. Voll method is largely determined by the accuracy of the obtained informative indicators recorded in arbitrary units of N “conductivity” for specified normalized values of the measuring current I ₀ , with a nonlinear dependence of the recorded “conductivity” and the measuring current on the normalized drop voltage U _o between the electrodes of the device, the type of non-linearity of which is determined in accordance with the "reference curve" Werner (table 1), where R _xo - normalized e value of the electrical resistance of the skin in the study area.

Table 1 N, conv. units 100 00 80 70 60 fifty 40 thirty twenty 10 I ₀ , μA 11.64 11.25 11.1 10.9 10 9.1 8.45 7.55 6.6 5.5 U _about mV 0 135 300 490 680 870 1090 1340 1670 2070 Rxo, kOhm 0 12 27 45 68 95 129 178 250 380

R. Voll's diagnostic devices should ensure the registration of the same values of the conductivity parameters N provided that the corresponding values of the normalized voltage drops U ₀ act between their electrodes or the corresponding normalized values of the electrical skin resistances R _xo are included, which can be represented as a nonlinear function f:

N = f (U) = f (R _x I). (1)

Possible inconsistencies of the nonlinear function of converting the conductivity parameters and the measuring current values of the “Werner reference curve” determine the errors of the devices for diagnostics by the method of R. Fold, and, as a consequence of this, decrease the reliability of diagnostic studies.

A device for measuring electrical resistance is known, intended for diagnosis by the method of R. Voll (Voll R. Arbeitsrichtlinien fur die Elektroakupwilctur. - ML Verlag, Hamburg, II Teil, 1963. - 102 s .; Kramer F. Textbook on electropuncture, T.I. - M .: IMEDIS, 1995. - 189 p.), Containing an indifferent electrode connected to the input of the amplifier (tube of a lamp triode) and through a resistor (R ₁ ) connected to a common power bus, a measuring electrode connected to the output of a controlled voltage source, the input of which is connected to the output of the subtraction unit (resistors are formed R ₂ and the power supply due to the antiphase voltages on connecting resistor R _1), inputs of which are separately connected to a source of reference voltage (output voltage of which is formed by the resistor R ₃₎ and the output of the amplifier and recorder connected to the amplifier output.

The known device provides the conversion of electric skin resistance, connected to the circuit between the measuring and indifferent electrodes for a given measuring current, and (or) the voltage drop between the electrodes into the output parameter values recorded using the recorder, determined in arbitrary units of "conductivity" in accordance with the "reference Werner curve.

At the same time, by turning on the resistor R _{1 in} series with the electric skin resistance, changing the voltage value supplied to the measuring circuit, and selecting the operating point of the amplifier in the non-linear section of the amplitude characteristic (tube triode), a predetermined non-linear function for converting the electric skin resistance (voltage drop between the electrodes) is formed in the values of the conventional units of "conductivity" and a given change in the measuring current, depending on the measured electrical resistance (The voltage drop between the electrodes) in accordance with the "reference curve" Werner.

The use of a nonlinear portion of the characteristic of a tube triode, the kind of nonlinearity of which for different lamp instances can be different, causes errors in the formation of a given nonlinear conversion function and a given change in the measuring current, which determines a decrease in the accuracy of measuring diagnostic parameters when using an analog device.

Moreover, in the device-analogue, in the process of setting up the device, it is necessary to select the operating point of the lamp triode in the non-linear section of the characteristic, which determines the difficulty of adjusting the device, and also to a certain extent causes an additional decrease in the accuracy of the measurement transformations.

In addition to the aforementioned, in the analog device, conversion of the electrical conductivity of the electric skin resistance (voltage drop) between the measuring and indifferent electrodes to the output recorded value is equal to the sum of the electric skin resistance (voltage drop) under the measuring and indifferent electrodes. As a result of this, during diagnostic studies on the parameters of acupuncture points, the recorded “conductivity” values will be affected by the electric skin resistance of the location zone of the indifferent electrode, as well as the voltage drop on the corresponding electric circuit, which additionally causes errors in the recorded values of the “conductivity” of the studied diagnostic acupuncture points .

In addition, in the general case, the voltage drop U between the electrodes of the device is determined by the voltage drop at the electro-cutaneous resistance R _x and compensating potentials E arising in the body to counteract the transmitted electric current I:

U = IR _x + E (2)

In accordance with expression (2), for the same values of N in the analog device, a different ratio of potentials E and electric skin resistances R _{x is} possible, which corresponds to different energy states of the body. As a result of this, the diagnostic information content of the recorded conductivity indicators is reduced when using an analog device.

Thus, the analog device does not provide high accuracy of measuring transformations and diagnostic informativeness of retested indicators, which determines a decrease in the reliability of diagnostic studies by the R. Voll method.

To a certain extent, the noted disadvantages of the analog device were eliminated in the device for searching acupuncture points (Russian patent 2108086, IPC A 61 B 5/05, A 61 H 39/02. Device for searching acupuncture points. / A.T. Seleznev, publ. 04/10/98), which can be used for diagnostics: according to the method of R. Voll, chosen as the second analog device. The device contains a measuring and two indifferent electrodes, a differential amplifier, a recorder and a controlled voltage source, the first output of which is connected to the measuring electrode, and the second output - with the first input of the differential amplifier and a common power bus, a subtractor, the output of which is connected to the input of the controlled voltage source , the first input is connected to the source of the reference voltage, and the second input to the recorder and through the amplitude detector to the output of the current-voltage converter жение pressure, the inputs of which are connected respectively to the first indifferent electrode and the output of the differential amplifier, the second input of the differential amplifier is connected to the second indifferent electrode. This analog device provides the formation of a nonlinear function of measuring transformations of the electric skin resistance (voltage drop between the electrodes.) Into the output voltage recorded by the recorder. In this case, by choosing the parameters of the elements used in the device, the correspondence of the conversion function of the device to the Werner “reference curve” can be provided to a certain extent. In addition, the device provides the conversion of electric skin resistance (voltage drop) of the location area of the measuring electrode with the exception of the influence on the measurement results of electric skin resistance (voltage drop) of the location area of the indifferent electrode. As a result of this, when using the second analog device for diagnostics according to the parameters of acupuncture points, errors from the influence of electric skin resistance (voltage drop) of the indifferent zone are eliminated. The absence of non-linear converting elements in the device greatly simplifies the adjustment and adjustment of the device, and also provides a high degree of repeatability of the specified non-linear conversion characteristics of informative parameters.

At the same time, the second analog device does not provide the required correspondence between the initial and final sections of the conversion characteristics of the electric skin resistance of the Werner “reference curve” both in terms of the non-linearity of the conversion and the given values of the measuring current, as well as the correspondence of the conversion characteristics in terms of voltage drops between measuring and indifferent electrodes, which is the reason for the appearance of measurement errors when using a device - analogue, which determine the bottom the reliability of diagnostic studies.

In addition, in the second analog device, as in the first analog device, due to the possible different ratios of the potentials E and the electric skin resistances of the studied area of the skin, the diagnostic information content of the recorded indicators is reduced, which is the reason for the additional decrease in the reliability of diagnostic studies.

Thus, the main disadvantages of the known analogue devices are the insufficient accuracy of the measurement conversions of the electric skin resistance (voltage drop between the electrodes) into the "conductivity" values for the given normalized values of the measuring current and low diagnostic information content of the obtained indicators, which determine the decrease in the reliability of diagnostic studies by the R. Voll method .

The closest in technical essence and the achieved result to the proposed technical solutions is a device for measuring electric skin resistance (Russian patent No. 2173537, IPC A 61 V 5/05, A 61 H 39/02. Device for measuring electric skin resistance. / AT Seleznev, N .A.Selezneva, Yu.V. Yurov, announced on April 27, 1999, published on September 29, 2001, Bull. No. 24), intended for diagnosis by the method of R. Voll, containing two amplifiers, a switch, the first input of which is connected to the first input of the first memory block, the second and third inputs are separately connected to the first and second indifferent electrodes, and the output is to the first input of the first amplifier, the second input of which is connected to the measuring electrode, a controlled voltage divider, the first input of which is connected to the output of the first memory unit, and the output to the combined first inputs of the comparator and the second memory unit, the second input of the comparator is connected to the output of the reference voltage source, and the output is to the second input of the first memory block, a subtraction unit, a multivibrator, two recorders, a resistor, a controlled voltage source, the first the output of which is connected to the measuring electrode and the second input of the first amplifier, the second output to the common power bus, and the input is connected to the output of the subtraction unit, the first input of which is connected to the output of the reference voltage source and the second input of the comparator, and the second input is connected to the output of the second amplifier and the second recorder, the first input of the second amplifier is connected to the second input of the switch, the first indifferent electrode and through a resistor connected to a common power bus, and the second input is connected to a common the power supply bus, the first output of the multivibrator is connected to the combined first inputs of the switch and the first memory block, the second output of the multivibrator is connected to the second input of the second memory block, the output of which is connected to the first recorder, the output of the first amplifier is connected to the second input of the controlled voltage divider.

The named device is selected as a prototype of the claimed devices as coinciding with them in the maximum number of signs.

In the prototype device, using the recorder for the output voltage of the second amplifier, the measuring conversion of the electric skin resistance (voltage drop) to the output signals recorded in arbitrary units of "conductivity" on a linear measuring scale, to a large extent, corresponding to the Werner "reference curve" formed when the use of linear converting elements of the device, which determines an increase in the accuracy of measuring transformations, and, consequently, an increase in reliability diagnostic studies on the method of R. Voll. In addition, the determination using the first recorder of the ratio of electric skin resistances (voltage drops) in the areas where the measuring and indifferent electrodes are located allows you to further increase the reliability of dagnosnogo indicators.

At the same time, the required degree of correspondence of the function of conversion of electric skin resistance (voltage drop), as well as a predetermined change in the values of the measuring current in the prototype device is not achieved in the entire range of measured values of electric skin resistance (voltage drop). As the authors note, the almost complete correspondence of the measuring scale to the Werner “reference curve” can be achieved only by using additional non-linear elements (for example, semiconductor diodes in the circuit of the second recorder) or a non-linear section of the amplitude characteristic of the second amplifier selected when setting up the device.

The prototype device also provides conversion to the output “conductivity” value of the sum of the electric skin resistances (voltage drops) of the location zones of the measuring and first indifferent electrodes, which determines the possibility of errors during diagnostic studies on the parameters of acupuncture points due to changes in the electric skin resistance (voltage drop) of the indifferent zones.

In addition to what is noted in the prototype device, as well as in analog devices, due to different ratios of compensating potentials E and electric resistance, corresponding to the same recorded values of the "conductivity" parameters, the diagnostic information content of the recorded parameters is reduced, which further reduces the reliability of the diagnostic tests when using the prototype device for the implementation of the diagnostic medical method of R. Voll.

Thus, the disadvantages of the known devices are determined by the insufficient accuracy of measuring informative parameters in the values of arbitrary units of "conductivity", the correspondence of the measuring current to normalized values determined by the "Werner" reference curve and low diagnostic information content of the recorded parameters.

The aim of the invention is to remedy the disadvantages noted.

The goal in the first embodiment of the device is achieved by the fact that in the device for diagnostics by the method of R. Voll containing a measuring electrode connected to the input of the first amplifier, two indifferent electrodes connected separately to the first and second inputs of the switch, two recorders, the first memory unit, the first the input of which is connected to the first output of the multivibrator, and the output to the first recorder, the second memory block, the second amplifier, the first calibrated resistor, a controlled voltage divider, the first block is subtracted a source and a reference voltage, two blocks, divisions, a third amplifier are introduced, the input of which is connected to the combined first outputs of the first and second calibrated resistors, and the output to the first input of the first division block, the first input of the first subtraction unit and the input of the voltage divider, the first input the second amplifier is connected to the output of the switch, and the output to the first indifferent electrode, the second input of the first division unit is connected to the output of the second subtraction unit, the first and second inputs of which are separately connected to the output m of the voltage divider and the first subtraction unit, the third memory unit, the first input of which is connected to the second output of the multivibrator and the first input of the controlled voltage divider, the second input is connected to the output of the second division unit, and the output to the second recorder, the third subtraction unit, the first input of which connected to the output of the second memory unit and the first input of the second division unit, and the output to the second input of the second division unit, the first input of the second memory unit is connected to the first output of the multivibrator, and the second input to the second the input of the first subtraction unit, the output of the first amplifier and the second input of the third subtraction unit, the second input of the controlled voltage divider is connected to the first output of the reference voltage source, and the output is to the second output of the second calibrated resistor, while the second input of the first memory block is connected to the output of the first block division, the second output of the first calibrated resistor is connected to the input of the first amplifier, and the second input of the second amplifier and the second output of the reference voltage source are connected to the common bus opitaniya.

The goal in the second embodiment of the device is achieved by the fact that the device for diagnostics by the method of R. Voll, containing a measuring electrode connected to the input of the first amplifier, two indifferent electrodes connected separately to the first and second inputs of the switch, two recorders, the first memory block, the first input of which is connected to the first output of the first multivibrator, and the output to the first recorder, the second memory block, the second amplifier, the first calibrated resistor, a controlled voltage divider, the first subtracting and the source of the reference voltage, two switches are introduced, a second multivibrator, the input of which is connected to the second output of the first multivibrator and the first inputs of the second and third switches, the first output is connected to the first input of the second memory block, and the second output to the first inputs of the third memory block and a controlled voltage divider, the third amplifier, the input of which is connected to the combined first terminals of the first and second calibrated resistors, and the output to the second input of the second switch, the first input of the first about the subtraction unit and the input of the voltage divider, the third input of the second switch is connected to the output of the second memory block and the first input of the third subtraction unit, and the output is to the first input of the division unit, the second input of which is connected to the output of the third switch, the second input of the third switch is connected to the output the second subtraction unit, the first and second inputs of which are separately connected to the outputs of the voltage divider and the first subtraction unit, the second input of the second memory unit is connected to the output of the first amplifier, the second input of the first the subtraction unit to the second input of the third subtraction unit, the output of which is connected to the third input of the third switch, the first input of the second amplifier is connected to the output of the first switch, and the output to the first indifferent electrode, the second input of the controlled voltage divider is connected to the first output of the reference voltage source, and the output is to the second output of the second calibrated resistor, and the second inputs of the first and third memory units are combined and connected to the output of the division unit, and the output of the third memory unit to the second registrar, wherein the second terminal of the first calibrated resistor connected to the input of the first amplifier and the second input of the second amplifier and the second output of the reference voltage source connected to a common power supply line.

The goal in the third embodiment of the device is achieved by the fact that in the device for diagnostics by the method of R. Voll, containing a measuring and two indifferent electrodes, the first switch, the inputs of which are separately connected to the first and second indifferent electrodes, two recorders, the first memory block, the output of which connected to the first recorder, the second memory block, the first input of which is connected to the first output of the first multivibrator, the second input is connected to the output of the comparator, and the output to the first input of the first control of the voltage divider, the first input of the comparator is connected to the first output of the reference voltage source, two amplifiers, the first calibrated resistor and the subtraction unit, two switches, three coincidence circuits, an "Or" element, two electronic keys, two memory blocks, a second controlled voltage divider , a second calibrated resistor and a second multivibrator, the first output of which is connected to the combined first inputs of the first and second coincidence circuits, the second output is connected to the input of the first multivibrator and the first inputs of the WTO of the first switch, the third match pattern and the first electronic key, the second output of the first multivibrator is connected to the second inputs of the second and third match patterns, the second input of the first match circuit is connected to the first input, the fourth memory block and the first output of the first multivibrator, the output of the first match circuit is connected to the first input of the third switch, the second input of which is connected to the first output of the first calibrated resistor and the measuring electrode, and the third input of the third switch and the second input of the second about the switch are connected to a common power bus, the third input of the second switch is connected to the second output of the first calibrated resistor and through the second calibrated resistor is connected to the output of the second controlled voltage divider, the first input of which is connected to the output of the third coincidence circuit, the first input of the third memory block and the first input circuit "Or", and the second input to the first output of the reference voltage source, the first input of the second electronic key is connected to the output of the circuit "Or", the second input of which is connected It is connected to the output of the second coincidence circuit and the first input of the first memory block, the second input of the second electronic key is connected to the output of the fourth memory block, the second input of the fourth memory block is connected to the combined outputs of the first electronic key and voltage divider, the input of the voltage divider is connected to the output of the module selection unit voltage, the first input of the subtraction unit and the second input of the first electronic key, the second input of the third memory unit is connected to the output of the third amplifier and the second inputs of the first memory unit and a comparator, and the output to the second recorder, the input of the voltage module isolation unit is connected to the output of the first amplifier, the first and second inputs of which are separately connected to the outputs of the second and third switches, the second input of the first controlled voltage divider is connected to the output of the subtraction unit, the second input of which is connected to the output of the second electronic switch, the output of the first controlled voltage divider is connected to the input of the third amplifier, the output of the first switch is connected to the first input of the second amplifier, the output to torogo connected to the first indifferent electrode, wherein the second output of the reference voltage source and a second input of the second amplifier connected to a common power supply line.

In this embodiment, devices for diagnosis according to the R. Voll method due to the introduction of two division blocks, a third amplifier, a second calibrated resistor, a third memory block, a voltage divider and two subtraction blocks in the first embodiment of the device, due to the introduction of two switches, a third amplifier, block division, a second calibrated resistor, a second multivibrator, a third memory block, a voltage divider and two subtraction units in the second embodiment of the device, as well as by introducing a second multivibrator, two comm trippers, a voltage module isolation unit, two electronic keys, three coincidence circuits, an "Or" circuit, two memory blocks, a voltage divider, a second calibrated resistor and a second controlled voltage divider, it is possible to obtain a high degree of compliance with a given measurement scale in arbitrary units of "conductivity" and normalized values of the measuring current of the "Werner" reference curve, and therefore, high measurement accuracy when implementing diagnostic modes according to the parameters of acupuncture points and pa ametram zones leads, and control information content derived parameters that determines the high accuracy of the diagnostic parameters for the implementation of a medical diagnostic method R.Foll.

The invention is illustrated by drawings, where figure 1 - figure 3 shows the functional diagrams of the first, second and third variants of the proposed devices.

According to the proposed devices, the equivalent circuit of the object of study (skin area) is presented in the form of a node 1, measuring electrode 2, second 3 and first 4 indifferent electrodes, switch (first switch in the second and third versions of the device) 5, first amplifier 6, second block 7 memory, the third subtraction unit 8 (subtraction unit 8 in the third embodiment of the device), the first calibrated resistor 9, the second division unit 10 (the division unit 10 in the second embodiment of the device), the second amplifier 11, the third amplifier 12, the second calibrated resistor 13, multivibrator 14 (first multivibrator 14 in the second and third versions of the device), first division unit 15, first memory unit 16, first subtraction unit 17, third memory unit 18, controlled voltage divider 19 (second controlled voltage divider 19 in the third embodiment devices), a voltage divider 20, a second subtraction unit 21, a second recorder 22, a first registrar 23, a reference voltage source 24, a second switch 25, a second multivibrator 26, a third switch 27, a voltage module isolation unit 28, a first electronic switch h 29, the third coincidence circuit 30, the first coincidence circuit 31, the fourth memory block 32, the second electronic key 33, the second coincidence circuit 34, the Ili circuit 35, the first controllable voltage divider 36 and the comparator 37.

Scheme 1 of skin substitution is presented as a Schaeffer model without taking into account the resistance of subcutaneous tissues (see Macs Phillippe. Study of human skin impedance for low-frequency currents. - These, dat. Ing. Univ. Nancy, 1973. - 96 p.), Where E ₁ , E ₂ and E ₃ are electrodermal (in general, including electrode, and when transmitting a measuring current and compensating) potentials, and R _x , R ₁ and R ₂ are electrodermal resistances at the points of location of measuring electrode 2, the second and first indifferent electrodes 3, 4, respectively.

The measuring electrode 2 is made in the form of a brass electrode with a spherical contact surface with a diameter of 3 mm. The second indifferent electrode 3 is made in the form of a brass electrode of a small area (about 2 ÷ 10 cm ² ) with a fixing device. The first indifferent electrode 4 is a piece of brass pipe with a diameter of 20 mm and a length of 110 mm.

Switch 5 (the first switch in the second and third device variants) is designed to connect the first input of the second amplifier 11 to the second 3 or first 4 indifferent electrodes when implementing measurement modes with three-point (when using two indifferent electrodes 3, 4 and connecting the first input of the second amplifier to second 3 indifferent electrode) and with a two-point (when using one indifferent electrode 4) connection to the skin. As the switch 5 can be used a switch, for example, type P2K.

The first amplifier 6 is a DC amplifier with a large input resistance (of the order of 100 MΩ or more) and is designed to transmit to the output circuit a voltage proportional to the voltage applied between its input and the common power bus (in the first and second versions of the devices), and applied between its inputs in the third embodiment of the device. The first amplifier 6 can be performed on K140UD12 and K154UD1 microcircuits in the first and second versions of the device in the form of a large-scale amplifier or a large-scale differential amplifier, one of the inputs of which is connected to a common power bus, and as a large-scale differential amplifier in the third embodiment of the device.

The second memory unit 7 is designed to store the voltage supplied to its second input when applying a control signal to the first input and transmitting it to the output with a given gear ratio. The second memory unit 7 is made in the form of an input electronic key, a storage capacitor and an output voltage amplifier. The K176KT1 microcircuit can be used as an input electronic key, and the K 140UD 12 microcircuit can be used as a voltage amplifier.

The third block 8 subtraction (block 8 subtraction in the third embodiment of the device) is designed to generate an output voltage proportional to the difference between the input voltages. The subtraction unit 8 can be performed on the chip K154UD1 in the form of a large-scale subtracting amplifier.

The first calibrated resistor 9 is designed to form a voltage drop from the measuring current and to ensure the given dependences of the "conductivity" and the measuring current in accordance with the Werner "reference curve". As the first calibrated resistor 9, an exact constant resistor with a resistance of 140 ± 1 kΩ was used.

The second division unit 10 (division unit 10 in the second embodiment of the device) is designed to generate an output voltage proportional to the quotient of the division of the input voltages supplied to its second and first inputs. Block 10 division can be performed on the chip MRY-100 firm Burr-Brown or AD534 firm Analog Devices.

The second amplifier 11 is a differential DC amplifier with a large input impedance and is designed to form the potential of a common connection point of electric skin resistances R _x , R ₁ , R ₂ equal to the potential of the common power bus when implementing the conversion mode with three-point connection by connecting the first indifferent electrode 4 to the output of the second differential amplifier 11, and the second indifferent electrode 3 to the first (inverting) input of the second differential amplifier 11 and supplying the potential of the common power bus to its second (non-inverting) input. The second (differential) amplifier 11 can be performed similarly to the first amplifier 6 used in the third embodiment of the device.

The third amplifier 12 is a DC amplifier with a large input resistance and is designed to transmit the input voltage to the output circuit. The third amplifier 12 is made similarly to the first amplifier 6 used in the first and second versions of the devices.

The second calibrated resistor 13 is designed to generate a given value of the measuring current in accordance with the "reference curve" Werner. As the second calibrated resistor 13, an exact constant resistor similar to the first calibrated resistor 9 with a resistance of 190 ± 1 kΩ can be used, so that the sum of the resistances of the first 9 and second 13 calibrated resistors is 330 ± 1 kΩ.

The multivibrator 14 (the first multivibrator in the second and third versions of the devices) is designed to alternately generate control signals at its first and second outputs. The multivibrator 14 in the first and second versions of the devices operates in a self-oscillating mode and is used as a generator of rectangular pulses. In the third embodiment of the device, the multivibrator 14 works as a single vibrator (delayed multivibrator), triggered by the input synchronization signal each time the second multivibrator 26 is switched and after each start it makes one complete oscillation. The multivibrator 14 is made on two "And" elements of the K561LA7 chip and the frequency-setting RC circuit; in the third version of the device, the synchronization input is organized in the multivibrator 14.

The first division unit 15 is designed to generate an output voltage proportional to the quotient of the division of the input voltages supplied to its second and first inputs. The first division block 15 can be performed similarly to the second division block 10.

The first memory block 16 is designed to store the voltage supplied to its second input when a control signal is applied to the first input. The first memory block 16 is made similarly to the second memory block 7 when performing a voltage amplifier in the form of a voltage follower with a single transmission coefficient.

The first subtraction unit 17 is designed to generate an output voltage proportional to the difference in input voltages. The first subtraction unit 17 can be performed similarly to the third subtraction unit 8 on the chip K 154UD1 in the form of a large-scale subtracting amplifier.

The third block 18 of the memory is designed to store the voltage supplied to its second input when applying to the first input of the control signal. The third memory block 18 is made similarly to the first memory block 16.

The controlled voltage divider 19 (the second controlled voltage divider 19 in the third embodiment of the device) is designed to change the transmission coefficient from unity to the selected value when a control signal is applied to its first input. The controlled voltage divider 19 can be performed on two resistors in the form of a voltage divider and an electronic key that opens (closes) when a control signal is applied, one resistor. In this case, as an electronic key, you can use one element of the K176KT1 chip with an input inverter, which can be used as one element of the K561LA7 chip.

The voltage divider 20 is designed to generate an output voltage from the input voltage with a transmission coefficient equal to 0.191. The divider 20 can be performed on two resistors.

The second subtraction unit 21 is designed to generate an output voltage proportional to the difference in input voltages. The second subtraction unit 21 may be performed similarly to the third subtraction unit 8.

The second recorder 22 is designed to register an indicator characterizing the information content of the measured parameter "conductivity" by the output voltage supplied to the recorder from the third memory unit 18. As the recorder 22 can be used arrow microammeter type M42103.

The first recorder 23 is designed to register the output measured parameter in arbitrary units of N "conductivity" according to the output voltage supplied to the recorder from the first memory block 16. The first registrar can be performed similarly to the second registrar 22.

The source 24 of the reference voltage is designed to generate a stabilized output voltage used to generate the measuring current passed between the measuring electrode 2 and the first indifferent electrode 4. As a source of 24 reference voltage, you can use a stabilized power source, the output voltage of which to implement the R. Voll method be equal to U _o = 3.90 ± 0.01 B.

The second switch 25 is designed to switch its output from the second input to the third input when a control signal is applied to its first input. The second switch 25 can be performed on the chip K561KP1.

The second multivibrator 26 is designed for alternately generating control signals at its first and second outputs. In the third version of the device, it operates in self-oscillating mode and is used as a generator of rectangular pulses. In the second embodiment of the device, the second multivibrator 26 operates as a single vibrator (delayed multivibrator), triggered by the input synchronization signal each time the first multivibrator 14 is switched and after each start it makes one complete oscillation. Multivibrator 26 is made similar to the first multivibrator 14 in the third embodiment of the device.

The third switch 27 is designed to switch its output from the second input to the third input when applying a control signal to the first input. The third switch 27 is made similar to the second switch 25.

Block 28 isolation module voltage is designed to convert the input voltage of positive and negative polarities into a unipolar output voltage. Block 28 can be performed on two type K 154 UD 1 microcircuits and KD522A semiconductor diodes.

The first electronic switch 29 is designed to close the circuits of its output and second input when applying a control voltage to the first input. It can be performed on one element of the type K 176KT 1 microcircuit.

The third coincidence circuit 30 is designed to generate an output control signal while supplying control inputs to its inputs. As the third coincidence circuit 30, two elements of the K561LA7 microcircuit can be used, one of which performs the function of an “AND-NOT” element, and the second of the inversion element “NOT”.

The first coincidence circuit 31 is designed to generate an output control signal while supplying control inputs to its inputs. The first match pattern 31 may be performed similarly to the third match pattern 30.

The fourth block 32 of the memory is designed to store the voltage supplied to its second input when applying to the first input of the control signal. The fourth memory block 32 is made similarly to the first memory block 16.

The second electronic switch 33 is designed to close the circuits of its output and second input when applying a control voltage to the first input. It can be performed similarly to the first electronic key 29 on one element of the chip type K176KT1.

The second coincidence circuit 34 is designed to generate an output control signal while supplying control inputs to its inputs. The second match pattern 34 may be performed similarly to the third match pattern 30.

The OR circuit 35 is designed to generate an output control voltage when applying control signals to its first or second input. As the "OR" circuit 35, two elements of the K561LE5 microcircuit can be used, one of which performs the function of the element, "OR NOT", and the second - the inversion element "NOT".

The first controllable voltage divider 36 is designed to change the voltage supplied to the input of the third amplifier 12 from the output of the subtraction unit 8 according to the control voltage supplied from the output of the second memory unit 7. The controlled voltage divider 36 is made according to the voltage divider circuit with a constant resistor and a controlled semiconductor resistance, which can be used as a KP103M1 field-effect transistor.

The comparator 37 is designed to compare the output voltage of the third amplifier 12 and the output voltage U _{0 of the} reference voltage source and generate a proportional output voltage. The comparator 37 can be performed on the chip K154UD1.

Devices for measuring electrical resistance are as follows. Before using the devices, you must first select the operating mode using the first switch 5.

When you connect using the switch 5 the first (inverting) input of the second amplifier 11 with the second indifferent electrode 3, the devices will work with a three-point connection to the skin, ensuring the exclusion of the influence on the output parameters of the electric skin resistances R ₁ , R ₂ and the corresponding voltage drops in the circuits of the indifferent electrodes . This mode is recommended when using devices for diagnostics according to parameters of acupuncture points, and can also be successfully used for diagnostics according to parameters of lead zones. In this case, under the condition of a high input resistance of the second amplifier 11, the current in the circuit of the second indifferent electrode 3 will be practically zero, and therefore, the potential of the connection point of the electric skin resistances R _x , R ₁ , R ₂ when neglecting the relatively small value of the electric skin potential E ₂ will be equal to the potential of the first input of the second amplifier 11, which in turn is equal to the potential of the second input of the second amplifier 11, determined by the potential of the common power bus, selected equal to zero. As a result of this, the value of the measuring current and the voltage drop across the electric skin resistance R _x and calibrated resistors 9, 13 will not depend on the electric skin resistance R ₁ , R _{2 of the} indifferent zones and the potential E ₃ , determined both by the electric skin and the compensating potentials of the location zone of the first indifferent electrode 4, which will determine the independence of the measured parameters recorded by the devices from the electrical parameter of the skin of the indifferent zones.

When connecting, using the switch 5, the first input of the second amplifier 11 with the first indifferent electrode 4, the devices will operate using a point-to-point connection to the skin, which is recommended during diagnostics according to the parameters of the lead zones. In this case, the second amplifier 11 will perform the function of a voltage follower, as a result of which the potential of the first indifferent electrode 4 will be determined by the potential of the second input of the second amplifier 11, equal to the potential of the common power bus, and the sum of the electrical skin resistances R _x1 = R _x will be considered as informative parameters + R ₂ (corresponding voltage drops at the resistances R _x , R ₂ ) of the measuring zones 2 and the first indifferent 4 electrodes. In this case, the second indifferent electrode 3 is not used. This measurement mode corresponds to the measurement mode used in known devices for diagnosis by the method of R. Voll.

When considering the operation of the claimed devices, we assume that the measurement of the parameter of "conductivity" is recorded by the values of the electric skin resistances, which allows us to not take into account the potential values E ₁ -E ₃ under the assumptions made (the validity of the aforementioned is determined by the fact that in the diagnostic devices R. Voll equal values of the parameters of "conductivity" are obtained in accordance with the "reference curve" Werner at certain values of electrical resistance and compensation sweat potentials).

The operation cycle of the first embodiment of the device using the multivibrator 14 is divided into two half-periods. Multivibrator 14 at its outputs alternately generates control signals In the first half-cycle, the control signal from the first output of multivibrator 14 acts on the first inputs of the second 7 and first 16 memory blocks, allowing signals that act on their second inputs to pass into the memory blocks. Moreover, at the second output of the multivibrator 14, the control signal is absent, as a result of which the third memory block 18 is closed, and the transmission coefficient of the controlled voltage divider 19 is equal to one.

After installing measuring 2 and indifferent electrodes 3, 4 from the source 24 of the reference voltage through a controlled voltage divider 19 in a serial measuring circuit including the first 9 and second 13 calibrated resistors, electrical resistance R _x , R ₂ and electric potentials E ₁ , E ₃ will be the measuring current I flows through the output circuit of the second amplifier 11 to the common power supply bus, the value of which without taking into account the potentials E ₁ , E ₃ will be equal to

where K ₁ is the transfer coefficient of the controlled voltage divider 19 U _о , is the output voltage of the source 24 of the reference voltage: R _о1 and R _о2 are the resistances of the first and second calibrated resistors 9 and 13, respectively.

When choosing the output voltage U _{about the} source 24 of the reference voltage equal to 3.9 V, the transfer coefficient of the controlled voltage divider 19 for the first half-life of the device K ₁ = 1, as well as the sum of the resistances of the calibrated resistors, equal to R _о1 + R _о2 = 330 kOhm, the measuring current I will, depending on the electric skin resistance R _x1, change in accordance with the Werner “reference curve”, which is confirmed by the values calculated in accordance with expression (3) and given in Table 2.

table 2 R _x1 , kOhm 0 12 27 45 68 95 129 178 250 380 I, μA 11.8 11,4 10.9 10,4 9.8 9.2 8.5 7.7 6.7 5.5 I _o , μA 11.64 11.25 11.1 10.9 10 9.1 8.45 7.55 6.6 5.5 Δ _I , μA 0.18 0.15 -0.18 -0.50 -0.20 0.08 0.05 0.13 0.12 -0.01 δ _I ,% 1,53 1.36 -1.58 -4.59 -2.01 0.84 0.55 1.68 1.88 -0.13

For comparison, Table 2 also shows the values of the measuring current l _о , determined by the Werner "reference curve", as well as the absolute Δ _I and relative δ _I errors of the values of the measuring current I for normalized values of the electric skin resistance R _x1 .

As can be seen from the above table, under the selected conditions, in the first half-periods of the device’s operation, a high compliance of the measuring current value I with the Werner “reference curve” is ensured with a relative error of values within the measuring range of electric skin resistances not exceeding 4.5%, and with the exclusion of a portion of the range ( at R _x1 = 45 kOhm) - no more than 2%.

From the measuring current I, voltage drops will be created on the electric skin resistances and calibrated resistors, as a result of which the voltages U ₁ and U ₂ are formed at the outputs of the first 6 and third 12 amplifiers:

where K ₂ and K ₃ are the transmission coefficients of the first 6 and third 12 amplifiers.

The output voltage U _{3 of the} first subtraction unit 17 will be determined by the expression

which, taking into account expressions (4), (5), will take the form

Denoting the transfer coefficient of the voltage divider 20 through K _{5, the} output voltage U _{4 of the} voltage divider 20 can be represented as

At the output of the second subtraction unit 21, a voltage U _{5 is} generated proportional to the difference of the output voltages U _{3 of the} first subtraction unit 16 and U _{4 of the} voltage divider 20, which, when the transmission coefficient of the second subtraction unit 21, K ₆ is equal to

Using the first division unit 15, in the first half-life of the first embodiment of the device, the output voltage U ₆ is formed proportional to the transfer coefficient K ₇ to the quotient of the output voltage U _{5 of the} second subtraction unit 21 and the output voltage U _{2 of the} third amplifier 12

The voltage U ₆ in the first half-life of the device when the control signal is applied to the first input of the first memory block 16 passes to the first memory block 16 and is stored in it.

Using the first recorder 23 provides registration of the parameter N "conductivity", determined by the output voltage U _{6 of the} first memory block 16:

When choosing the transmission coefficients of devices from the conditions

Expression (8) takes the form

Given the previously selected resistance value of the calibrated resistor R _o1 finally for the measured parameter N "conductivity" we obtain the expression

To check the correspondence of expression (10) to the Werner “reference curve”, the parameter N was calculated for different values of electric skin resistance R _x1 . The calculation results are given in table.3.

Table 3 R _x1 , kOhm 0 12 27 45 68 95 129 178 250 380 N 100.0 90.2 80.0 69.9 59.6 50,0 40.7 30.8 20.8 9.7 N _o 100 90 80 70 60 fifty 40 thirty twenty 10 Δ _N 0,0 0.2 0,0 -0.1 -0.4 0,0 0.7 0.8 0.8 -0.3 δ _N % 0,0 0.3 0,0 -0.1 -0.7 0.1 1.8 2.7 3.8 -3.3

Here, for comparison, the values of the “conductivity” N ₀ determined by the Werner “reference curve” are given, as well as the absolute Δ _N and relative δ _N errors of the values of the measured parameter N “conductivity” for the normalized values of the electric skin resistance R _x1 .

As can be seen from the above table, in the first embodiment of the device, a high correspondence of the values of the measured parameter N of the "conductivity" to the corresponding values of N ₀ : Werner's "reference curve" is ensured. Thus, the relative error in measuring electric skin resistance in arbitrary units of “conductivity” within the measuring range of electric skin resistances from 0 to 380 kOhm does not exceed 3.8%, and within the measuring range from 0 to 178 kOhm - 2.7%.

When the state of the multivibrator 14 changes during the second half-periods of operation of the first embodiment of the device, a control signal is generated at the second output of the multivibrator 14. As a result, the third memory block 18 is opened, and the transmission coefficient of the controlled voltage divider 19 changes from unity K ₁ = 1 to the value K ₁ = K _1o .

In this case, the inputs of the first 16 and second 7 memory blocks are closed, and the voltage remains equal to U ₆ determining the value of the N conductivity parameter N at the output of the first memory block 16 in the second half-wire of operation of the multivibrator 14, and the voltage is determined by the output voltage at the output of the second memory block 7 U _{1 of the} first amplifier in the first half-cycle of the multivibrator 14.

Taking into account that when the measuring current is passed through the body, compensating potentials E are created, in accordance with expression (2), voltages U _1.1 and U _1.2 are formed at the input of the first amplifier 6 in the first and second half-periods of operation of the device, the values of which can be represented as

where I ₁ , I ₂ - measuring currents in the first and second half-periods of operation of the device; E - compensating potential; R _x1 * -registered electric skin resistance when taking into account the compensating potential.

In the General case, the value of the compensating potential E depends on the value of the measuring current and may differ in the first and second half-periods of operation of the device. But when you select close in value of the measuring currents I ₁ and I ₂ , and also taking into account a certain inertia of the formation and change of the compensating potential E, which, when choosing the minimum possible value of the half-life of the device, allows you to provide a practically constant value of the compensating potential E in two half-periods of the device .

From the conditions for the implementation of R. Voll’s diagnostic tools, in accordance with Werner’s “reference curve”, voltage drops across electro-skin resistances U _1.1 in the first half-periods of the device’s operation for the same values of the measured parameters N “conductivity” must be equal to the corresponding voltage drops U ₁ regardless values of the compensating potential E:

Moreover, in accordance with the last expression, the measuring current in the first half-cycle of the device also does not depend on the value of the compensating potential and is equal to the current I

In view of the above, expression (11) can be rewritten in the form

The voltage U _1.1 (U ₁ ) in the first half-life of the device when the control signal is applied to the first input of the second memory unit 7 is stored in the second memory unit 7 and transmitted to its output with a transfer coefficient K ₈ .

The output voltage U _{1.2 of the} first amplifier 6 in the second half-cycle of the device operates on the second input of the third subtraction unit 8, the first input of which in the second clock cycle supplies the output voltage of the second memory unit 7. As a result of this, the voltage U ₆ is formed at the output of the third subtraction unit 8 in the second clock

where K ₉ is the transfer coefficient of the third block 8 of the subtraction.

Given expression (12), expression (13) can be rewritten as

Measuring currents I ₁ and I ₂ , taking into account expression (3), provided that the transmission coefficient K _{1 of the} controlled voltage divider 19 in the first cycle is equal to one, and in the second cycle it changes to K _1o can be represented as

Substituting expressions (15), (16) into expression (14) for voltage U _6, we write:

Using the division unit 10 in the second clock cycle of the device, the voltage U ₆ is supplied to the first input of the division unit 10 by the voltage U _1.1 supplied to the second input of the division unit 10 from the output of the second memory unit 7. As a result of this, a voltage U _{7 is} formed at the output of the division side 10, equal to taking into account expressions (12), (17) with the transmission coefficient K ₁₀ of the division unit 10

Taking into account that, taking into account expression (11), the electric skin resistance R _x1 can be represented as

Moreover, expression (18) can be rewritten in the form

The voltage U ₇ is supplied to the second input of the third memory unit 18, the first input of which in the second half-cycle of the device provides a control signal, and is stored in it. At the same time, using the second recorder 22 in the device, the parameter proportional to the voltage U ₇ is monitored by the output voltage of the third memory unit 18, which should be called the information content of the “conductivity” parameter registered by the device.

If during the implementation of the device to choose the values of the transmission coefficients K ₈ = 1 / K _1o , then the expression (19) takes the form

As expression (20) shows, in the first embodiment of the device, using the second recorder 22, a parameter is determined, the value of which at constant values of the parameters of the device elements (K ₁₀ , K ₉ , K ₈ , and K _1o ) depends on the compensating potential E. the product U = I ₁ R _x1 is the voltage drop across the electric skin resistance R _{x1 of the} day of each value N of the "conductivity" in accordance with the Werner "reference curve" is constant.

The value of the compensating potential E for each value of the "conductivity" parameter N can vary from zero to I ₁ R _x1 and the recorded conductivity index N can be qualitatively characterized by the voltage U ₇

Thus, the indicator recorded using the second recorder 22 determines the weight influence with respect to the voltage drop U = I ₁ R _x1 in the "conductivity" index N of the compensating potential E, which corresponds to the concept of the information content of the recorded "conductivity" indicator.

As expression (20) shows, the information content indicator, which can be arbitrarily designated P _in , with the value of the compensating potential E = 0 is zero (P _in = 0), with an increase in the value of the compensating potential E to the value E = I ₁ R _x1, the information _content indicator increase, reaching a maximum at E = I ₁ R _x1 equal to

Moreover, there cannot be a larger value of E from the condition for the formation of a Werner “reference curve”, according to which the same values of the “conductivity” correspond to a given resistance R _x1 and a given voltage drop U across it.

In the second embodiment of the device, similarly to the first embodiment of the device, with the help of the first multivibrator 14 operating in self-oscillating mode, the operation cycle is divided into two half-cycles, and with the help of the second multivibrator 26 the second half-oscillator is divided into two cycles. In the first half-cycle, a control signal is generated at the first output of the first multivibrator 14 and opens the first memory block 16. Moreover, at the second output of the first multivibrator 14 in the first half-cycle of the device, the control signal is absent. As a result of this, the control signal does not act on the first inputs of the second 25 and third 27 switches, as a result of which their outputs are connected to the second inputs. A control signal is supplied to the first input of the second memory unit 7 in the first half-cycle, allowing the output voltage of the first amplifier to pass to the second memory unit 7 and to its output, as well as storing this voltage.

Provided that the transfer coefficients of the switches 25 and 27 are equal to unity, the voltages supplied to the first and second inputs of the division unit 10 will correspond to the voltages U ₂ and U _{5 of the} first embodiment of the device supplied to the first and second inputs of the first division unit 15 in the first half-cycle the operation of the first embodiment of the device.

As a result of this, provided that the transfer coefficient of the division unit 10 of the second embodiment of the device is equal to the transmission coefficient of the first division unit 15 (K ₇ ) of the first embodiment of the device, the output voltage of the division unit 10 in the first half-life of the second embodiment of the device will correspond to the output voltage U _{3 of the} first unit 15 dividing the first variant of the device in the first half-life of the device.

The output voltage of the division unit 10 in the second embodiment of the device is supplied to the first input of the first memory unit 16, the first input of which, in the first half-cycle of the device, the control signal is supplied from the output of the first multivibrator 14 and stored in the first memory unit 16.

Using the first recorder 23 in the second embodiment of the device, the output voltage of the first memory unit 16 is used to register the parameter N of the "conductivity", which fully corresponds, on the basis of expression (8), to the registered parameter N of the "conductivity" in the first embodiment of the device, the values of which when the parameters of the second variant devices similar to the first embodiment of the device, largely correspond to the values of N _o "reference curve" Werner.

When the state of the first multivibrator 14 changes in the second half-cycle of the second embodiment of the device, a control signal is generated at its second output. In this case, the switches 25 and 27 are switched, as a result of which their outputs are connected to the third inputs. This closes the first memory block 16, and the voltage at its output remains constant during the second half-cycle of the device.

According to the control signal from the second output of the first multivibrator 14, the second multivibrator 26 is launched, which divides the second half-cycle of the device into two clock cycles. In the first cycle, a control signal is generated at the first output of the second multivibrator 26 and acts on the first input of the second memory unit 7, as in the first half-cycle of the device, as a result of which the output voltage of the first amplifier U ₁ passes to the second memory unit 7 and is stored in it.

In the first cycle of the second half-cycle, at the second output of the second multivibrator 26, there is no control signal, as a result of which the transmission coefficient of the controlled voltage divider 19 is K ₁ = 1, and the third memory unit 18 is closed at the first input.

When the state of the second multivibrator 26 changes in the second cycle of the second half-cycle, a control signal is generated at the second output of the second multivibrator 26. As a result, the transmission coefficient of the controlled voltage divider 19 is changed to the value K ₁ = K _{1 о} , and the third memory unit 18 is opened. In this case, the second memory unit 7 is closed, and its output voltage at a transmission coefficient of the second memory unit 7 equal to K ₈ , during the second clock cycle of the second half-cycle will be equal to the voltage U ₈

U ₈ = K ₈ U _1.1 .

This voltage is supplied to the first input of the third subtraction unit 8, to the second input of which a voltage U ₁₂ is applied, as a result of which the voltage U ₆ corresponding to expression (13) is generated at the output of the third subtraction unit 8.

The voltage U ₆ through the third switch 27 is applied to the second input of the division unit 10, the first input of which through the second switch 25 is supplied with the output voltage of the third amplifier 12, which in the second cycle of the second half-cycle is equal to the voltage U ₁₂ . As a result of this, a voltage U ₇ is generated at the output of the division unit 10, corresponding to expression (18), which under conditions similar to the conditions selected for the first embodiment of the device will be determined by expression (20).

This voltage passes to the memory unit 18, open in the second cycle of the second half-cycle of the second variant of the device, and is stored in it. In this case, as in the first embodiment of the device, using the second recorder 22 in the second embodiment of the device, the parameter P _{inf is} informative.

In the third embodiment of the device, the second multivibrator 26 operates in self-oscillating mode and, in accordance with its state, divides the device’s operation cycle into two half-periods, the first multivibrator 14 operating in standby mode, dividing at each start both when the control signal is turned on and off on the second the output of the second multivibrator 26 each half-cycle for two cycles.

In the first half-life of the third variant of the device, a control signal is generated at the first output of the second multivibrator 26, while the first multivibrator 14 is simultaneously launched, at the first output of which a control signal is generated in the first clock cycle. As a result of this, from the output of the first coincidence circuit 31, a control signal is supplied to the first input of the third switch 27, connecting its output to the third input. The control signal from the first output of the second multivibrator 26 acts on the first input of the second switch 25 in the first half-life of the third embodiment of the device, as a result of which the output of the second switch 25 is connected to the third input.

In this case, the first input of the first amplifier 6 is connected to the second output of the first calibrated resistor 9, and the second input is connected to a common power bus.

In the first half-life of the device at the output of the third coincidence circuit 30, there is no control signal, as a result of which the third memory block 18 is closed at the first input, and the transmission coefficient of the controlled voltage divider 19 is K ₁ = 1.

As a result of this, the output voltage U _{9 of the} first amplifier 6 with its gain coefficient K ₁₁ will correspond to the voltage U ₂ :

This voltage passes through the voltage module isolation unit 28 and is supplied to the first input of the subtraction unit 8 and the input of the voltage divider 20.

Since the first electronic switch 29 is closed in the first half-cycle (there is no control signal at its first input), a voltage U ₁₀ is formed at the output of the voltage dividing unit 20 with a dividing factor K ₅ , which corresponds to the unity of the transmission coefficient of the voltage isolation unit 28 of the voltage module U ₄ first variant of the device

Since the control signal acts on the first input of the fourth memory block 32 in the first clock cycle of the first half-cycle, the voltage U ₁₀ passes to the fourth memory block 32, is stored in it and transmitted to its output with the transfer coefficient K ₈ .

In this case, the second electronic key 33 is closed, since there are no control signals at the first and second inputs of the Ili circuit 35 due to the fact that no control signals are received at the second input of the second coincidence circuit 34, as well as the first and second inputs of the third coincidence circuit 30. As a result of this, the voltage supplied to the second input of the subtraction unit 8 is equal to zero, and therefore, the output voltage U _{11 of the} unit 8 with a transmission coefficient equal to K ₁₂ will be equal to

This voltage passes through the first controllable voltage divider 36, the transmission coefficient of which K ₁₃ is determined by the output voltage of the second memory unit 7, and the output voltage U _{12 of the} first controllable voltage divider 36 will be

Using the third amplifier 12, the gain of which in the third embodiment of the device is K ₁₄ , the input voltage is amplified, which at the output of the third amplifier 12 will be equal to

Using a comparator 37, the voltage U _{13 is} compared with the voltage U _{0 of the} source 24 of the reference voltage, and in proportion to their difference, a voltage is generated at the output of the comparator 37, which passes to the second memory unit 7, which is opened at the first input by a control signal from the first output of the first multivibrator 14.

When the output voltage of the second memory unit 7, which is determined by the output voltage of the comparator 37, changes, the transfer coefficient K _{13 of the} first controlled voltage divider 36 occurs. As a result of this, the voltage U ₁₃ and, consequently, the output voltage of the comparator 37 are changed. The process of changing the voltage U ₁₃ and the gear ratio U ₁₃ will occur until the voltage U ₁₃ becomes equal to the voltage U _o , that is:

where K _13-0 the transmission coefficient of the first controllable divider 36 when the condition for equal voltage U ₁₃ = U ₀ .

From the expression (21) we can determine the value of the coefficient K _13-0

When the state of the first multivibrator 14 changes in the second cycle of the first half-cycle, a control signal is generated at its second output. In this case, the control signal is also generated at the output of the second coincidence circuit 34, which acts on the first input of the first memory block 16, opening it, and through the "Ili" 35 at the first input opens the second electronic key 33. At the same time, the fourth memory block 32 closes, the output whose voltage at the transmission coefficient K ₈ remains equal to K ₈ U ₁₀ , and the control signal at the first output of the third switch 27 is turned off, which leads to the connection of the output of the third switch 27 with its second input.

As a result of this, the voltage U ₁₄ corresponding to the voltage U ₃ in the first embodiment of the device is formed at the output of the first amplifier 6 when the amplification factors of the first 6 and third 12 amplifiers of the first embodiment of the device are

This voltage through the block 28 of the selection of the voltage module will affect the first input of block 8 subtraction, the second input of which is affected by the voltage from the output of the fourth block 32 of the memory.

As a result of this, the voltage U _{15 is} formed at the output of the subtraction unit 8 in the second clock cycle of the first half-cycle

The voltage U ₁₅ passes through the first controlled voltage divider 36, the transmission coefficient of which in the second cycle of the first half-cycle remains equal to K _13-0 and is amplified by the third amplifier 12. As a result, the voltage U _{13-1 is} formed at the output of the third amplifier 12:

выражение (22.1) будет полностью соответствовать выражению (9) до постоянного коэффициента пропорциональности, определяющему зависимость параметра информативности N от электрокожного сопротивления R_x1 в первом варианте устройства.When choosing transmission coefficients of devices from the condition

expression (22.1) will fully correspond to expression (9) to a constant proportionality coefficient, which determines the dependence of the information content parameter N on electric skin resistance R _x1 in the first embodiment of the device.

Thus, the third version of the device provides registration of the parameter "conductivity" in accordance with the "reference curve" Werner.

The voltage U _{13-1 is} stored in the first memory block 16, opened in the second clock cycle of the first half-cycle at the first input and is recorded using the first “conductivity” parameter recorder 23. In this case, a constant coefficient of proportionality equal to 123.6 can be realized in the third embodiment of the device by selecting the sensitivity of the recorder 23.

When the state of the second multivibrator 26 changes in the second half-cycle of the third variant of the device, a control signal is generated at its second output. This also starts the first multivibrator 14, dividing the second half-cycle into two clock cycles. In the first cycle, a control signal is generated at the first output of the first multivibrator 14.

As a result of this, in the second half-cycle, the first memory block 16 is closed and the control signal is turned off at the first inputs of the second 25 and third 27 switches, which leads to the closure of the outputs of the switches to the second inputs. In this case, the second input of the first amplifier 6 is connected to the first output of the first resistor, and the first input is connected to a common power bus.

In the first cycle of the second half-cycle, the control signal is not supplied to the first input of the second controlled voltage divider 19, as a result, its transmission coefficient K ₁ = 1, and the fourth memory block 32 is opened at the first input.

As a result of this, a voltage U ₁₆ corresponding to a voltage of U _1.2 for the first embodiment of the device is generated at the output of the voltage module isolation unit 28 in the first clock cycle of the third operation period of the device.

This voltage, through the first electronic switch 29, open in the second half-cycle, passes into the fourth memory block 32 and is stored in it.

At the same time, the voltage U ₁₆ is supplied to the first input of the subtraction unit 8, to the second input of which the voltage is not supplied in the first cycle (equal to zero), because the second electronic key 33 is closed at the first input, as a result of the fact that there are no control signals at the first and second inputs of the second match circuit 34 and the second input of the third match circuit 30.

As a result of this, the output voltage of the subtraction unit 8 will be equal to

This voltage passes through the first controlled voltage divider 36 and the second amplifier 12, as a result of which the voltage U _14-2 is formed at the output of the second amplifier 12:

The voltage U _14-2 in the first cycle of the second half-cycle using the comparator 37 is compared with the voltage U _{o of the} source 24 of the reference voltage. As a result of this, a voltage is generated at the output of the comparator 37 in proportion to the difference in the input voltages, which passes to the first memory unit 7, which is opened at the first input by a control signal from the first input of the first multivibrator 14. As a result, when the output voltage of the first memory unit 7 changes To _{13 of the} first controlled voltage divider 36, and therefore the output voltage U _{14-2 of the} third amplifier.

The process of changing the transmission coefficient K ₁₃ and the output voltage U _14-2 will occur until the voltage U _14-2 is equal to the voltage U _o :

When this condition is met, the transmission coefficient K _13-2 will be equal to

When the state of the first multivibrator 14 changes in the second cycle of the second half-cycle, a control signal is generated at its second output. As a result of this, the first block 7 and the fourth block 32 are closed at the first inputs and the output signal of the third coincidence circuit 30 at the first inputs opens the third block 18 of the memory and the second electronic key 33, and the transmission coefficient of the second controllable is changed to K ₁ = K _1o voltage divider.

As a result of this, the value of the measuring current changes to a value of I ₂ and a voltage is applied to the first input of the subtraction unit 8

The second input of the subtraction unit 8 is affected by the voltage U ₁₇ from the output of the fourth memory block 32.

At the output of the subtraction unit 8, a voltage U _11-3 is formed equal to:

Given the expressions for the measuring currents (15), (16), expression (23) can be rewritten in the form:

The voltage U _11-3 passes through the first controlled voltage divider 36 and the third amplifier 12, and the voltage U _13-2 , equal to

Transforming the expression (24) provided that

we get:

выражение (25) примет видWhen choosing

expression (25) takes the form

Expression (26) fully corresponds to expression (20), provided that U _o = K ₁₀ K ₉ , which shows the same possibility of highlighting the information content index P _in in the third embodiment of the device.

The voltage U _{13-2 is} stored in the third memory block 18, open at the first input, and using the first recorder 22, the voltage U _13-2 is used to control the information _content index P _in, similar to the first embodiment of the device.

Thus, the proposed three device options, when choosing the appropriate values of the element parameters, ensure the registration of the measured values of electric skin resistance in arbitrary units of "conductivity" in accordance with the Werner "reference curve", as well as additionally control of the information content parameter, which determines the high reliability, information content and accuracy of the recorded parameters in accordance with the diagnostic method of R. Voll both when using a traditional two-point connection, and three Spot metering connection to the skin, which allows to eliminate the influence on the measurement results of the electric resistance of neutral zones.

Claims (12)

1. Device for diagnostics by the method of R. Voll, containing a measuring electrode connected to the input of the first amplifier, two indifferent electrodes connected separately to the first and second inputs of the switch, two recorders, the first memory unit, the first input of which is connected to the first output of the multivibrator, and the output is to the first recorder, a second memory unit, a second amplifier, a first calibrated resistor, a controlled voltage divider, a first subtraction unit and a reference voltage source, characterized in that given two division blocks, a third amplifier, the input of which is connected to the combined first terminals of the first and second calibrated resistors, and the output is to the first input of the first division block, the first input of the first subtraction unit and the input of the voltage divider, the first input of the second amplifier is connected to the output of the switch, and the output is to the first indifferent electrode, the second input of the first division block is connected to the output of the second subtraction block, the first and second inputs of which are separately connected to the outputs of the voltage divider and the first block in readings, the third memory unit, the first input of which is connected to the second output of the multivibrator and the first input of the controlled voltage divider, the second input is connected to the output of the second division unit, and the output to the second recorder, the third subtraction unit, the first input of which is connected to the output of the second memory unit and the first input of the second division block, and the output is to the second input of the second division block, the first input of the second memory block is connected to the first output of the multivibrator, and the second input is to the second input of the first subtraction block, the output is not of the first amplifier and the second input of the third subtraction unit, the second input of the controlled voltage divider is connected to the first output of the reference voltage source, and the output is to the second output of the second calibrated resistor, while the second input of the first memory unit is connected to the output of the first division unit, the second output of the first calibrated a resistor is connected to the input of the first amplifier, and the second input of the second amplifier and the second output of the reference voltage source are connected to a common power bus. 2. The device according to claim 1, characterized in that the sum of the resistances of the first and second calibrated resistors is selected equal to 330 kOhm, and the output voltage of the reference voltage source is 3.9 V. 3. The device according to claim 1 and 2, characterized in that the resistance of the first calibrated resistor is selected equal to 140 kOhm. 4. The device according to claims 1 to 3, characterized in that the transmission coefficient of the voltage divider is selected equal to 0.191. 5. Device for diagnostics by the method of R. Voll, containing a measuring electrode connected to the input of the first amplifier, two indifferent electrodes connected separately to the first and second inputs of the switch, two recorders, the first memory unit, the first input of which is connected to the first output of the first multivibrator and the output is to the first recorder, the second memory unit, the second amplifier, the first calibrated resistor, a controlled voltage divider, the first subtraction unit and the reference voltage source, characterized in that in two switches were introduced, the second multivibrator, the input of which is connected to the second output of the first multivibrator and the first inputs of the second and third switches, the first output is connected to the first input of the second memory block, and the second output is to the first inputs of the third memory block and controlled voltage divider, the third an amplifier whose input is connected to the combined first terminals of the first and second calibrated resistors, and the output to the second input of the second switch, the first input of the first subtraction unit and the input of the divider The third input of the second switch is connected to the output of the second memory block and the first input of the third subtraction unit, and the output is to the first input of the division unit, the second input of which is connected to the output of the third switch, the second input of the third switch is connected to the output of the second subtraction unit, the first and the second inputs of which are separately connected to the outputs of the voltage divider and the first subtraction unit, the second input of the second memory unit is connected to the output of the first amplifier, the second input of the first subtraction unit and the second input of the third about the subtraction unit, the output of which is connected to the third input of the third switch, the first input of the second amplifier is connected to the output of the first switch, and the output to the first indifferent electrode, the second input of the controlled voltage divider is connected to the first output of the reference voltage source, and the output to the second output the second calibrated resistor, the second inputs of the first and third memory units are combined and connected to the output of the division unit, and the output of the third memory unit to the second recorder, while the second output of the first of the calibrated resistor connected to the input of the first amplifier and the second input of the second amplifier and the second output of the reference voltage source connected to a common power supply line. 6. The device according to claim 5, characterized in that the sum of the resistances of the first and second calibrated resistors is selected equal to 330 kOhm, and the output voltage of the reference voltage source is 3.9 V. 7. The device according to claim 5 and 6, characterized in that the resistance of the first calibrated resistor is selected equal to 140 kOhm. 8. The device according to PP.5 to 7, characterized in that the transmission coefficient of the voltage divider is selected equal to 0.191. 9. A device for diagnostics by the method of R. Voll, containing a measuring and two indifferent electrodes, a first switch, the inputs of which are separately connected to the first and second indifferent electrodes, two recorders, a first memory unit, the output of which is connected to the first recorder, a second memory unit, the first input of which is connected to the first output of the first multivibrator, the second input is connected to the output of the comparator, and the output is to the first input of the first controlled voltage divider, the first input of the comparator is connected to the first at the output of the reference voltage source, two amplifiers, a first calibrated resistor and a subtraction unit, characterized in that two switches, three coincidence circuits, an OR element, two electronic keys, two memory blocks, a second controlled voltage divider, a second calibrated resistor and the second multivibrator, the first output of which is connected to the combined first inputs of the first and second coincidence circuits and the second switch, the second output is connected to the input of the first multivibrator and the first inputs of the third coincidence circuit and the first electronic key, the second output of the first multivibrator is connected to the second inputs of the second and third matches, the second input of the first matches is connected to the first input of the fourth memory block and the first output of the first multivibrator, the output of the first matches is connected to the first input of the third switch, the second input which is connected to the first output of the first calibrated resistor and the measuring electrode, and the third input of the third switch and the second input of the second switch are connected to a common electric bus power supply, the third input of the second switch is connected to the second output of the first calibrated resistor and through the second calibrated resistor is connected to the output of the second controlled voltage divider, the first input of which is connected to the output of the third coincidence circuit, the first input of the third memory block and the first input of the OR circuit, and the second input - to the first output of the reference voltage source, the first input of the second electronic key is connected to the output of the OR circuit, the second input of which is connected to the output of the second coincidence circuit and the first the input of the first memory block, the second input of the second electronic key is connected to the output of the fourth memory block, the second input of the fourth memory block is connected to the combined outputs of the first electronic key and voltage divider, the input of the voltage divider is connected to the output of the voltage module allocation unit, the first input of the subtraction unit and the second the input of the first electronic key, the second input of the third memory block is connected to the output of the third amplifier and the second inputs of the first memory block and comparator, and the output to the second recorder , the input of the voltage module isolation unit is connected to the output of the first amplifier, the first and second inputs of which are separately connected to the outputs of the second and third switches, the second input of the first controlled voltage divider is connected to the output of the subtraction unit, the second input of which is connected to the output of the second electronic switch, the output of the first a controlled voltage divider is connected to the input of the third amplifier, the output of the first switch is connected to the first input of the second amplifier, the output of which is connected to the first indifferent electrode, while the second output of the reference voltage source and the second input of the second amplifier are connected to a common power bus. 10. The device according to claim 9, characterized in that the sum of the resistances of the first and second calibrated resistors is selected equal to 330 kOhm, and the output voltage of the reference voltage source is 3.9 V. 11. The device according to claims 9 to 10, characterized in that the resistance of the first calibrated resistor is selected equal to 140 kOhm. 12. The device according to PP.9 - 11, characterized in that the transmission coefficient of the voltage divider is selected equal to 0.191.

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