RU2251270C2 - Herbicides for tolerant or resistant maize cultures and method for controlling of weeds - Google Patents

Abstract

FIELD: agriculture, in particular method for controlling of weeds.

SUBSTANCE: claimed method for controlling of weeds in tolerant maize cultures includes application of composition comprising (A) road spectrum herbicide from group (A1) glufosinate (salt) and analogs, (A2) glyfosate (salt) and analogs; (B) one or more herbicides from group (B1) cyanazin, alachlor, nicosulfurone, rimsulfurone, sulkotrion, mesotrion, and penthoxamid; (B2) pendimethalyne, methosulam, isoxaflutol, metribuzin, chloransulam, flumetsulam, linuron, florasulam, and isoxachlorotol; and (B3) bromoxinyl, chlorpyralid, tifensulfuron, MCPA (2-methyl-4-chlorophenoxyacetic acid), halosulfuron, and sulfosulfuron, wherein (A) and (B) components are in synergic effective ration. Also disclosed are herbicidal compositions including compound from group (A1) or )F2) and herbicide from group (B).

EFFECT: effective controlling of weeds in tolerant maize cultures.

6 cl, 55 tbl, 3 ex

Description

The invention relates to the field of plant protection products that can be used to control weeds in tolerant or resistant crops of maize and contain, as an active herbicidal component, a combination of two or more herbicides.

With the introduction of tolerant or resistant varieties and lines of corn crops, in particular transgenic varieties and lines of corn crops, the well-known weed control system is replenished with new active substances that are not in themselves selective in ordinary varieties of corn. Active substances are, for example, well-known broad-spectrum herbicides such as glyphosates, sulfosates, glufosinates, bialaphos and herbicides - imidazolinone derivatives [herbicides (A)], which can now be used for tolerant crops developed for them accordingly. The effectiveness of these herbicides in relation to weeds (weeds) in tolerant crops is at a high level, but still depends, similarly to the treatment with other herbicides, on the type of herbicide used, its consumption rate (input amounts), and the current composition , from the type of weeds to be eradicated, from the climate and soil conditions and so on. In addition, there are cases when herbicides exhibit weak activity (or are generally not active) in relation to certain types of weeds. The next criterion is the duration of action, respectively, the decay rate of the herbicide. In some cases, changes in the sensitivity of weeds that may occur with prolonged use of herbicides or in the case of geographic specificity (geographical restrictions) should also be taken into account.

The loss of activity in relation to individual plants can only be compensated conditionally, if at all possible, due to the large quantities of herbicides used. In addition, there is always a need for methods that can achieve the effectiveness of herbicides with less active substances. When using smaller amounts, not only the amount of active substance required for administration is reduced, but also, as a rule, the amount of necessary auxiliary agents of the composition is reduced. Both factors reduce economic costs and improve the environmental situation (tolerance) when treated with herbicides.

The possibility of improving the profile (nature) of the use of the herbicide can consist in combining the active substance with one or more other active substances that bring the desired additional properties. However, the combined use of several substances often reveals phenomena of physical and biological incompatibility, for example, insufficient stability of the combined composition, decomposition of the active substance, or antagonism of the active substances. In contrast, combinations of active substances with a favorable action profile, high stability and, if possible, with an enhanced synergistic effect, which allow a reduction in the amount administered compared to using the combined active substances separately, are desirable.

In a striking way, it was found that active substances from the group of the aforementioned herbicides (A) with a wide spectrum of action in combination with other herbicides from the group (A) and in some cases with certain herbicides (B) together work in a particularly favorable way when they are used in corn crops which are suitable for the selective use of the first of the above herbicides.

The subject of the invention is thus the use of a combination of herbicides for weed control in corn crops, characterized in that the corresponding combination of herbicides contains the following components that act synergistically:

(A) a broad spectrum herbicide from the group of compounds, which consists of

(A1) compounds of formulas (A1)

where Z is a residue of the formula —OH or a peptide residue of the formula —NCH (CH ₃ ) CONCH (CH ₃ ) COOH or —NCH (CH ₃ ) CONCH [CH ₂ CH (CH ₃ ) ₂ ] COOH, and their esters and salts, preferably glufosinate and its salts with acids and bases, in particular ammonium glufosinate, L-glufosinate and their salts, bialaphos and its salts with acids and bases and other phosphinotricin derivatives,

(A2) compounds of formula (A2) and their esters and salts,

preferably glyphosates and their salts with alkali metals and salts with amines, in particular isopropylammonium glyphosate, and sulfosates,

(A3) imdazolinones, preferably imazetapur, imazapur, imazametabenz, imazametabenzmethyl, imazachine, imazamox, imazapic (AC 263222) and their salts, and

(A4) azoles having herbicidal properties from the group of protoporphyrinogen oxidase inhibitors (PPO inhibitors), e.g. WC 9717 (= CGA276854), and

(A5) herbicides derived from cyclohexanedione, and, if necessary, also

(A6) herbicides derived from heteroaryloxyphenoxypropionic acid,

and

(B) one or more herbicides from the group of compounds, which consists of

(B0) one or more structurally distinct herbicides from the above group (A) and / or

(B1) herbicides acting against monocotyledonous and dicotyledonous weeds, with action on foliage and soil, and / or

(B2) herbicides used selectively in maize against dicotyledonous weeds, and / or

(B3) herbicides that act on foliage and soil and which can be used selectively in corn crops mainly against dicotyledonous weeds, or herbicides from several groups (B0) to (B3),

and corn crops are tolerant to the combination herbicides (A) and (B), in some cases in the presence of preservation agents.

With “structurally different herbicides from the named group (A)” in group (B0), only herbicides are considered that are covered by the definition of group (A) but are still not contained in the corresponding combinations as component (A).

Along with the claimed combinations of herbicides, other active substances from plant protection products and auxiliary substances commonly used for plant protection, and auxiliary agents in the compositions can also be used.

Synergistic actions are observed with the joint use of active substances (A) and (B), but can still be detected with time-divided use (separation into parts). It is also possible to apply herbicides or a combination of herbicides in several portions (sequential application), for example, after application before germination, application after germination should be made, or after application in the early period after germination, application should be made in the middle or late period after germination. In this case, it is preferable to simultaneously add the active substances of the current combination, in some cases in several portions. But it is also possible time-divided application of the individual active substances of the combination, and in a certain case it can be beneficial. With this systemic application, other plant protection products, such as fungicides, insecticides, acaricides and the like and / or various auxiliary substances, additives and / or fertilizers, can also be combined (integrated).

Synergistic effects can reduce the used amounts of individual active components, increase the effectiveness of the action in relation to the same weed species with the same amounts used, control previously unreached species (gaps), expand the temporary space when applied and / or as a result for users who applies - economically and environmentally friendly weed control systems.

For example, thanks to the claimed combinations of (A) + (B), synergistic efficiencies become possible that far and unexpectedly exceed the efficiencies achieved with the individual active components (A) and (B).

International application WO-A-98/09525 describes a method for controlling weeds in transgenic crops that are resistant to phosphorus-containing herbicides such as glufosinate or glyphosate, using combinations of herbicides that contain glufosinate or glyphosate and at least one herbicide from the group consisting of prosulfuron, primisulfuron, dicamba, pyridate, dimethenamide, metolachlor, flumethuron, propachisafop, atrazine, clodinafop, norflurazone, ametrine, terbutylazine, simazine, promethrin, NOA-4029- 3 ( chlorpyridazi ), The compound of formula

where R is 4-chloro-2-fluoro-5- (methoxycarbonylmethylthio) phenyl, (known from US patent US-A-4671819), CGA276854 = 1-allyloxycarbonyl-1-methylethyl ether 2-chloro-5- (3-methyl -2,6-dioxo-4-trifluoromethyl-3,6-dihydro-2H-pyrimidin-1-yl) benzoic acid (= WC9717, known from US patent US-A-5183492) and 4- oxetanyl ether 2- {N - [N- (4,6-dimethylpyrimidin-2-yl) aminocarbonyl] aminosulfonyl} benzoic acid (known from European patent application EP-A-496701).

Details regarding the possible and achievable effects can be found in international application WO-A-98/09625. There are no examples of synergistic effects or experimentation in certain cultures, as well as specific combinations of two, three or more herbicides.

Several combinations of herbicides with glufosinate or L-glufosinate and other herbicides such as alloxidime, linuron, MCPA, 2,4-D, dicamba, trichlopur, 2,4,5-T are already known from the German patent application DE-A-2856260 , MSRV and others.

From the international application WO-A-98/08353 and European patent application EP-A 0252237, certain combinations of herbicides with glufosin or glyphosate and other herbicides from a number of sulfonylureas (s), such as metsulforonomethyl, nicosulforon, primisulforon, rimsulforon and so on, are already known .

The use of combinations to control weeds in literary sources is shown only in a small number of plant species, but not even shown in the examples.

In our own experiments, it was found that there is a strikingly large difference between the applicability of the combinations of herbicides mentioned in international application WO-A-08/09525 and other sources, and other combinations of new type herbicides in plant cultures.

According to the invention, combinations of herbicides are patented which can be particularly advantageously used in tolerant corn crops.

The compounds of formulas (A1) to (A4) are known or can be obtained by analogy with known methods.

Formula (A1) includes all stereoisomers and mixtures thereof, in particular a racemate and, accordingly, a biologically active enantiomer, for example L-glufosinate and its salts. Examples of active substances of the formula (A1) are as follows:

(A 1.1) Glufosinate in the narrow sense, that is,

D, L-2-amino-4- [hydroxy (methyl) phosphinyl] butanoic acid,

(A1.2) Glufosinate-monoammonium salt,

(A1.3) L-Glufosinate, L- or (2S) -2-amino-4- [hydroxy (methyl) phosphinyl] butanoic acid (Phosphinotricin)

(A1.4) L-glufosinate-monoammonium salt,

(A1.5) Bialafos (or Bilanafos), i.e., L-2-amino-4- [hydroxy (methyl) phosphinyl] butanoyl-L-alanyl-L-alanine, in particular its sodium salt.

The named herbicides (A1) to (A5) act on the green parts of the plants and are known as broad-spectrum herbicides or continuous herbicides; they are inhibitors of the glutamine synthetase enzyme in plants; see. "The Pesticide Manual" 11 ^th Edition, British Crop Protection Council 1997, S.643-645 bzw. 120-121. In the case where the field of application in the post-emergence method of controlling weeds and unwanted cereals on plantations with crops and on uncultivated lands, using the special application technique, also extends to row-spacing control in agricultural field crops, such as corn, cotton and the like, the importance of the use of selective herbicides in resistant transgenic cultures is increasing.

Glufosinate is usually used in the form of a salt, preferably an ammonium salt. The ammonium glufosinate or glufosinate racemate is usually used alone in dosages that lie between 50 and 2000 g AB / ha, preferably between 200 and 2000 g AB / ha (= g ai / ha = gram of active substance per hectare). At such dosages, glufosinate is effective when it acts on the green parts of plants. Since it breaks down in the soil with the help of microbes for several days, it does not have a sufficiently long action in the soil. A similar situation also exists for the applied active substance bialafos-sodium (identical to bilanafos-sodium); see. "The Pesticide Manual" 11 ^th Edition, British Crop Protection Council 1997, S.120-121.

In the claimed combinations, as a rule, obviously less active substance (A1) is needed, for example, the amount used can lie in the range from 20 to 800, preferably from 20 to 600 grams of the active substance, glufosinate per hectare (g AB / ha or g a.i ./ha). Appropriate amounts, preferably amounts expressed in moles per hectare, are also suitable for ammonium glufosinate and bialaphos or sodium bialafos.

Combinations with leaf acting herbicides (A1) are used in a targeted manner in crops that are resistant or tolerant to compounds (A1). Some tolerant crops that are genetically engineered are already known and used in practice, cf. article in the journal Zuckerrübe 47. Jargang (1998, S.217 ff; for producing transgenic plants that are resistant to glufosinate, cf. European patent applications EP-A-0242246, EP-A-242236, EP-A -257542, EP-A-275967, EP-A-0513054).

Examples of compounds (A2) are

(A2.1) Glyphosate, i.e. N- (phosphonomethyl) glycine,

(A2.2) Glyphosate - monoisopropylammonium salt,

(A2.3) Glyphosate - sodium salt,

(A2.4) Sulfosate, i.e. N- (phosphonomethyl) glycine - trimesium salt = N- (phosphonomethyl) glycine-trimethylsulfoxonium salt.

Glyphosate is usually used in the form of a salt, preferably a monoisopropylammonium salt, or a trimethylsulfoxonium salt (trimesium salt

= sulfosate). Based on glyphosate free acid, the final dosage lies in the range of 0.050-5 kg AB / ha, preferably 0.5-5 kg AB / ha. Glyphosate, from the point of view of some technical aspects, is similar to glufosinate, but nevertheless, in contrast to the latter, it is an inhibitor of the enzyme 5-enolpyruvil-chicate-3-phosphate synthase in plants; see. "The Pesticide Manual" 11 ^th Edition, British Crop Protection Council 1997, S.646-649.

In the claimed combinations, the necessary amounts for use, as a rule, lie in the range from 20 to 1000, preferably from 20 to 800 g AB / ha of glyphosate.

For compounds (A2), gene-engineered tolerant plants that have been put into practice are also already known; Wed "Zuckerrübe" 47. Jargang (1998, S.217 ff; cf. also international application WO 92/00377, European patent applications EP-A-115673, EP-A-409815.

Examples of imidazolinone derivative herbicides (A3) are

(A3.1) Imazapur and its salts and esters,

(A3.2) Imazetapur and its salts and esters,

(A3.3) Imazametabenz and its salts and esters,

(A3.4) Imazametabenzyl methyl,

(A3.5) Imazamox and its salts and esters,

(A3.6) Imazahine and its salts and esters, e.g. ammonium salt,

(A3.7) Imazapic (AC 263222) and its salts and esters, for example, the ammonium salt.

Herbicides inhibit the enzyme acetolactate synthase (ALS) and thereby protein synthesis in plants; they are effective both in the action on the leaves (contact action) and when applied to the soil, and in cultures exhibit partial selectivity (s); Wed "The Pesticide Manual" 11 ^th Edition, British Crop Protection Council 1997, S.697-699 are (A3.1), S.701-703 are (A3.2), S.694-696 relate to (A3 .3) and (A3.4), S.696-697 refer to (A3.5), S.699-701 refer to (A3.6) and S. 5 and 6, are referenced under AC 263222 (refer to A3 .7). The amounts of herbicides used are usually between 0.01 and 2 kg AB / ha, preferably from 0.1 to 2 kg AB / ha. In the claimed combinations, they lie in the region from 10 to 800 g AB / ha, preferably from 10 to 200 g AB / ha.

Combinations with imidazolinones are used specifically in maize cultures that are resistant to imidazolinones. Such tolerant cultures are already known. European patent application EP-A-0360750 describes, for example, the preparation of plants tolerant to ALS inhibitors (acetolactate synthase) by selection or gene-engineering. Tolerance of plants in relation to herbicides is caused due to the increased content of ALS in plants. US-A-5198599 describes sulfonylurea and imidazolinone tolerant plants that have been bred by selection.

Examples of PPO inhibitors are

(A4.1) Pyraflufen and its esters, such as pyraplufen-ethyl,

(A4.2) Carfentrazone and its esters, such as carfentrazone-ethyl,

(A4.3) Oxadiargil,

(A4.4) Sulfentrazone,

(A4.5) WC9717 or CGA276854 = 1-allyloxycarbonyl-1-methylethyl ether 2-chloro-5- (3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydro-2H-pyrimidin-1- il) benzoic acid (known from US patent US-A-5183492).

These azoles are known as protoporphyrinogen oxidase (PPO) enzyme inhibitors in plants; see. "The Pesticide Manual" 11 ^th Edition, British Crop Protection Council 1997, S.1048-1049 are (A4.1), S.191-193 are (A4.2), S.904-905 are (A4.3) and S.1126-1127 refer to (A4.4).

Tolerant plant cultures have already been described. The introduced amounts of azoles are, as a rule, in the range from 5 to 200 g AB / ha.

Some plants tolerant of PPO inhibitors are already known.

Examples of herbicides derived from cyclohexanone (A5) are:

(A5.1) Sethoxydim ( "Pesticide Manual" 11 ^th Ed., British Crop Protection Council 1997 (hereinafter "PM" s.1101-1103), i.e. (E, Z) -2- (1-etoksiimino- butyl) -5- [2- (ethylthio) propyl] -3-hydroxy-cyclohex-2-enone,

(A5.2) Cycloxydim (PM, p. 290-291), i.e. 2- (1-Ethoxyiminobutyl) -3-hydroxy-5-thian-3-ylcyclohex-2-enone,

(A5.3) Cletodim (RM, p. 250-251), that is, 2 - {(E) -1 - [(E) -3-chloroallyloxyimino] -

propyl} -5- [2- (ethylthio) propyl] -3-hydroxy-cyclohex-2-enone,

(A5.4) “Clefoxidim” or “BAS 625 H” (see AG Chem. New Compound Review, Vol.17, 1999, S.26, published by AGRANOVA) (= 2- [1- (2- (4- chlorophenoxy) propoxyimino) butyl] -3-oxo-5-thion-3-yl-cyclohex-1-enol),

(A5.5) Tralkoxydim (PM, p. 1211-1212), i.e. = 2- [1- (ethoxyimino) propyl] -3-hydroxy-5-mesitylcyclohex-2-enone.

Herbicides inhibit mitosis and thereby the synthesis of fatty acids in plants; this is especially true for leaf-bearing herbicides, and they exhibit partial selectivity (s) in crops. Consumption rates (quantities used) of herbicides are usually between 0.2 and 1 kg AB / ha. In the claimed combinations, they usually lie in the range from 10 to 1000 g AB / ha. Combinations with cyclohexanedione are used specifically in corn crops that are resistant to cyclohexanedione. Such tolerant cultures are already known.

Examples of heteroarylphenoxyphenoxypropionic acid herbicides are:

(A6.1) "Fenoxaprop-R" and its esters, such as ethyl ether "Fenoxaprop-P-ethyl" (see RM, p. 519-520) (= (R) -2- [4- (6- chlorobenzoxazolyl-2-yloxy) phenoxy] propionic acid or its ethyl ester is also used in the form of the phenoxaprop-R racemate and its esters such as ethyl ester and / or

(A6.2) “Quisalofop-R" and its esters, such as ethyl or tefuryl

ether, (see PM, pp. 1089-1092) (= (R) -2- [4- (6-chloroquinoxalin-2-yloxy) phenoxy] propionic acid or its ethyl ether or tetrahydrofurfuryl ether, is also used in the form of a racemate Quizalofop and its esters; compare also in the form of the special propachisaphop ether (compound A6.3) and / or (A6.3) propachisafop (RM, p.1021-1022), Hizalofop 2-isopropylidene aminooxyethyl ether -P and / or

(A6.4) “Fluazifop-R” and its esters, such as butyl ether (see PM, p. 566-557) (= (R) -2- [4- (5-trifluoromethyl-pyrid-2-yloxy ) phenoxy] -propionic acid or its butyl ether), is also used in the form of the fluazifop racemate and its esters, and / or

(A6.5) “Haloxifop-R” and its esters, such as methyl ether (see RM, p. 660-663) (= (R) -2- [4- (3-chloro-5-trifluoromethyl-pyrid -2-yloxy) phenoxy] propionic acid or its methyl ester), is also used in the form of a galoxifop racemate and its esters, such as methyl or ethyl ether, and / or

(A6.6) “Tsigalofop” and its esters, such as butyl ether (see RM, p. 297-298) (= (R) -2- [4- (4-cyano-2-fluorophenoxy) phenoxy] propionic acid or its butyl ether), and / or

(A6.7) Clodinafop and its esters, such as propargyl ether (see PM, p. 251-252) (= (R) -2- [4- (5-Chloro-3-fluoro-pyrid-2 -yloxy) phenoxy] propionic acid or its propargyl ether).

Herbicides (A6) are known as fatty acid biosynthesis inhibitors and are used in amounts of 5-500 g AB / ha. In the claimed combinations, the amounts used can be partially further reduced, for example, to 1-300 g AB / ha. Herbicide combinations (A6) are used purposefully in corn crops that are tolerant to herbicides; this is also observed in crops that are tolerant of herbicides derived from cyclohexanedione (A5).

As a partner (B) in combination, for example, compounds of the following groups (B1) to (B4) are considered:

(B1) Herbicides that are active both on the foliage and on the soil, and which can be selectively used against weeds and dicotyledonous weeds, for example, the following compounds [data given: “common name” and pages from the link “The Pesticide Manual "11 ^th Edition, British Crop Protection Council 1997, abbreviated" PM "];

(B1.1) Cyanazine (PM, p. 280-283), i.e. 2- (4-chloro-6-ethyl-amino-1,3,5-triazin-2-ylamino) -2-methyl-propionitrile

(B1.2) Atrazine (PM, p. 55-57), i.e., N-ethyl-N’-isopropyl-6-chloro-2,4-diamino-1,3,5-triazine,

(B1.3) Terbutylazine (PM, p. 168-1170), i.e., N-ethyl-N’-tert-butyl-6-chloro-2,4-diamino-1,3,5-triazine,

(B1.4) Acetochlor (PM, p.10-12), i.e. 2-chloro-N- (ethoxymethyl) -N- (2-ethyl-6-methylphenyl) -acetamide,

(B1.5) Metolachlor (PM, p. 833-834), i.e. 2-chloro-N- (2-ethyl-6-methylphenyl) -N- (2-methoxy-1-methylphenyl) acetamide,

(B1.6) Alachlor (PM, p.23-24), i.e. 2-chloro-N- (2,6-diethylphenyl) -N- (methoxymethyl) acetamide,

(B1.7) Terbutrin (PM, p. 1170-1172), i.e., N- (1,1-dimethylethyl) -N'-ethyl-6-methylthio-2,4-diamino-1,3,5-triazine ,

(B1.8) Benoxacor (PM, pp. 102-103), i.e. 4-dichloro-acetyl-3,4-dihydro-3-methyl-2H-1,4-benzoxazine,

(B1.9) Nicosulfuron (PM, p. 877-879), i.e. 2- (4,6-dimethoxypyrimidin-2-yl) -3- (3-dimethylcarbamoyl-2-pyridylsulfonyl) -urea,

(B1.10) Rimsulfuron (PM, pp. 1095-1097), i.e. 2- (4,6-dimethoxypyrimidin-2-yl) -3- (3-ethylsulfonyl-2-pyridylsulfonyl) -urea,

(B1.11) Promsulfuron and its esters, such as methyl ether (PM, p. 997-999), i.e. 2- [4,6-bis (difluoromethoxy) -pyrimidin-2-ylcarbamoylsulfamoyl] benzoic acid or its methyl ester ,

(B 1.12) Dimethenamide (PM, p. 409-410), i.e. 2-chloro-N- (2,4-dimethyl-3-thienyl) -N- (2-methoxy-1-methylethyl) acetamide,

(B1.13) Flutiamide (BAY FOE 5043, flufenacet) (PM, p. 82-83), i.e. 4'-Fluoro-N-isopropyl-2- (5-trifluoromethyl-1,3,4-thiadiazole-2 -yloxy) acetanilide,

(B1.14) Sulcotrione (PM, p.1124-1125), i.e. 2- (2-chloro-4-mesylbenzoyl) cyclohexane-1,3-dione,

(B1.15) Simazine (PM, p. 1106-1108), i.e. 6-chloro-N, N’-diethyl-2,4-diamino-1,3,5-triazine,

(B1.16) Mesotrione, i.e. 2- (4-mesyl-2-nitrobenzoyl) -cyclohexane-1,3-dione (ZA1296, cf. Weed Science Society of America (WSSA) in WSSA Abstracts 1999, Bd. 39, Seite 65-66, Ziffern 130-132),

(B1.17) Pentoxamide (PM, pp. 1095-1097), i.e. 2-chloro-N- (2-ethoxyethyl) -N- (2-methyl) -1-phenyl-1-propenyl) acetamide (TCS- 94, known from AG Chem. New Compound Review, Vol.17 (1999), European Patent Application EP-A-206251),

and in the case where the active substances from group (B1) are in the form of racemic mixtures, preferably the active substance is also in the form of a pure or enriched active isomer,

(B2) herbicides used selectively in maize against dicotyledonous weeds, for example compounds:

(B2.1) Pendimethalin (PM, p. 937-939), i.e. N- (1-ethylpropyl) -2,6-dinitro-3,4-xylidine,

(B2.2) Pyridate (PM, pp. 1064-1066), i.e., O- (6-chloro-3-phenylpyridazin-4-yl) ester, S-octyl ester of thiogaric acid,

(B2.3) Iodosulfuron (proposed generic name) and preferably methyl ether (cf. WO 96/41537), i.e. 4-iodine-2- (4-methoxy-6-methyl-1,3,5-triazin-2 -alkarbamoylsulfamoyl) benzoic acid or its methyl ester, known from international application WO 92/13845,

(B2.4) Metosulam (PM, p. 836-495), that is, 2 ', 6'-dichloro-5,7-dimethoxy-3'-methyl- [1,2,4] triazolo [1,5a] pyrimidine-2-sulfoanilide,

(B2.5) Isoxaflutol (PM, p. 737-739), i.e. (5-cyclopropyl-4-isoxazolyl) [2-methylsulfonyl-4- (trifluoromethyl) phenyl] methanone,

(B2.6) Metribuzin (PM, s.), I.e. 4-amino-6-tert-butyl-3-methylthio-1,2,4-triazin-5 (4H) -one,

(B2.7) Chloransulam and preferably methyl ether (PM, p. 165), i.e. 3-chloro-2- (5-ethoxy-7-fluoro- [1,2,4] triazolo- [1,5-s ] pyrimidin-2-yl sulfamido) benzoic acid or its methyl ester,

(B2.8) Flumetsulam (PM, p. 573-574), i.e. 2 ', 6'-dichloro-5-methyl- [1,2,4] triazolo- [1,5-s] pyrimidin-2- sulfonanilide,

(B2.9) Linuron (PM, p. 751-753), i.e. 3- (3,4-dichlorophenyl) -1-methoxy-1-methyl-urea,

(B2.10) Florasulam, i.e. N- (2,6-Difluorophenyl) -8-fluoro-5-methoxy- [1,2,4] triazolo- [1,5-c] pyrimidin-2-sulfonanilide (DE -570, cf. Zeitschrift Pfl. Krankh. PflSchutz, Sonderblatt XVI, 527-534 81 1998),

(B2.11) Isoxaclortol, i.e. (4-chloro-2- (methylsulfonyl) phenyl) (5-cyclopropyl-4-isoxazolyl) ketone, European patent application EP-A-470856)

and in the case where the active substances from group (B2) are in the form of racemic mixtures, preferably the active substance is also in the form of a pure or enriched active isomer,

(B3) herbicides which are herbicides with action on foliage and on soil and can be selectively used in corn, mainly against dicotyledonous weeds, for example, compounds:

(B3.1) Bromoxynil (PM, p. 149-151), i.e. 3,5-dibromo-4-hydroxybenzonitrile,

(B3.2) Dicamba (PM, p. 356-357), i.e. 3,6-dichloro-o-anisic acid and its salts,

(B3.3) 2,4-D (PM, p. 323-327), i.e., 2,4-dichlorophenoxyacetic acid and its salts and esters,

(B3.4) Clopiraralide (PM, p. 260-263), i.e. 3,6-dichloro-2-pyridinecarboxylic acid and its salts and esters,

(B3.5) Prosulfuron (PM p.1041-1043), i.e. 1- (4-methoxy-6-methyl-1,3,5-triazin-2-yl) -3- [2- (3.3 , 3-trifluoropropyl) phenylsulfonyl] urea,

(B3.6) Tifensulfuron and its esters, preferably methyl ether (PM, p. 188-1190), i.e. 3 - [[[[(4-methoxy-6-methyl-1,3,5-triazin-2- il) amino] carbonyl] amino] sulfonyl] -2-thiophenecarboxylic acid or its methyl ester,

(B3.7) Carfentrazone and its salts and esters, preferably ethyl ether (PM, p. 191-193), i.e. 2-chloro-3- [2-chloro-5-

(4-difluoromethyl-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl) -4-fluorophenyl] propionic acid or its ethyl ester,

however, combinations with the compound (A4.2) by definition do not represent herbicidal combinations of various herbicidal active substances and are thereby excluded,

(B3.8) LAB271272 (= trisulfuron, CAS Reg. No. 142469-14-5; see AG Chem. New Compound Review, Vol.17, 1999, S.24, issued by AGRANOVA, i.e. N - [[((4 -methoxy-6-trifluoromethyl-1,3,5-triazin-2-yl) amino] carbonyl] -2- (trifluoromethyl) benzenesulfamide, and

(B3.9) MCPA (PM, p. 767-769), i.e. (4-chloro-2-methylphenoxy) acetic acid and its salts and esters,

(B3.10) Halosulfuron and its esters, such as methyl ether (PM, p. 657-659), i.e. 3-chloro-5- (4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl) -1-methylpyrazole- methyl ester 4-carboxylic acid, also in the form of its salt,

(B3.11) Diflufenzopur (BASF 654 00 N) (PM, p. 81-82), i.e. 2- {1- [4- (3,5-difluorophenyl) semicarbazone] ethyl} nicotinic acid and its salts,

(B3.12) Sulfosulfuron (PM, p. 1130-1131), i.e. 1- (4,6-dimethoxypyrimidin-2-yl) -3- (2-ethylsulfonylimidazo [1,2-a] pyridin-3-ylsulfonyl )urea,

and in the case where the active substances from group (B3) are in the form of racemic mixtures, preferably the active substance is also in the form of a pure or enriched active isomer.

In the case of active substances based on carboxylic acids or other salts of ester-forming active substances, the name of the herbicide should in general, also include salts and esters, preferably common commercial salts and esters, in particular commonly used active forms, through the common name of the acid.

The amounts of herbicides (B) used can vary greatly from herbicide to herbicide. The following areas can be named as a rough approximation of true quantities:

For compounds (B0): 1-3000 g AB / ha, preferably 5-2000, [cf. data for the group of compounds (A)] For compounds (B1): 0.1-5000 g AB / ha, preferably 1-5000 g AB / ha, For compounds (B2): 0.1-5000 g AB / ha, preferably 1-3000 g AB / ha, For compounds (B3): 0.1-5000 g AB / ha, preferably 1-3000 g AB / ha,

In some cases, the following applicable amounts (consumption rates) in g AB / ha are preferred:

(B1.1) - (B1.8) 100-5000 g, preferably 200-4000, particularly preferably 300-3500 (B1.9) - (B1.11) 0.1-120, preferably 200-4000, particularly preferably 1-90,

(B.1.12) 50-5000, preferably 100-4000, particularly preferably 300-3500, (B.1.13) 100-2000, preferably 200-1500, particularly preferably 300-1200, (B.1.14) 50-1000, preferably 100-600, particularly preferably 200-3500, (B.1.15) 100-5000, preferably 200-4000, particularly preferably 300-3500, (B.1.16) 10-500, preferably 25-300, particularly preferably 50-200, (B.1.17) 5-1500, preferably 10-1000, particularly preferably 20-800, (B.2.1) 100-3000, preferably 200-2500, particularly preferably 300-2000, (B.2.2) 100-2500, preferably 200-2000, particularly preferably 300-1500, (B.2.3) 0.1-100, preferably 0.2-20, particularly preferably 0.5-15, (B.2.4) 1-200, preferably 5-150, particularly preferably 10-100, (B.2.5) 5-300, preferably 10-200, particularly preferably 20-150, (B.2.6) 10-1500, preferably 25-1000, particularly preferably 50-800, (B.2.7) 2-200, preferably 2.5-100, particularly preferably 5-80, (B.2.8) 5-500, preferably 10-300, particularly preferably 20-200,

(B2.9) 50-2500, preferably 100-2000, particularly preferably 200-1000, (B2.10) 0.5-100, preferably 1-20, particularly preferably 3-15, (B2.11) 5-300, preferably 10-200, particularly preferably 20-150, (B3.1) 50-1000, preferably 100-600, particularly preferably 200-500, (B3.2) 5-2500, preferably 100-2000, particularly preferably 200-1500, (B3.3) 50-3000, preferably 100-2000, particularly preferably 200-1500, (B3.4) 10-300, preferably 20-250, particularly preferably 40-200, (B3.5) 1-100, preferably 2-70, particularly preferably 5-50, (B3.6) 0.5-100, preferably 1-50, particularly preferably 2-40, (B3.7) 1-250, preferably 5-120, particularly preferably 10-100, (B3.8) 1-200, preferably 5-150, particularly preferably 10-120, (B3.9) 50-3000, preferably 100-2000, particularly preferably 200-1500, (B3.10) 1-200, preferably 5-150, particularly preferably 10-50, (B3.11) 5-1000, preferably 10-500, particularly preferably 20-80, (B3.12) 1-150, preferably 5-100, particularly preferably 5-80,

Quantitative ratios of compounds (A) and (B) are taken from the above amounts used for individual substances, and the following quantitative ratios are of particular interest:

(A) :( B) in the range from 18000: 1 to 1: 5000, preferably from 2000: 1 to 1: 1000, particularly preferably from 200: 1 to 1: 100,

(A) :( B0) in the range from 1000: 1 to 1: 400, preferably from 400: 1 to 1: 400, particularly preferably from 200: 1 to 1: 200,

(A1) :( B1) in the range from 1500: 1 to 1: 300, preferably from 400: 1 to 1: 250, particularly preferably from 200: 1 to 1: 100,

(A1) :( B2) in the range from 10000: 1 to 1: 300, preferably from 1500: 1 to 1: 250, particularly preferably from 1000: 1 to 1: 100, completely preferred from 200: 1 to 1: 100,

(A1) :( B3) in the range from 2000: 1 to 1: 300, preferably from 1500: 1 to 1: 250, particularly preferably 200: 1 to 1: 100,

(A2) :( B1) in the range from 2500: 1 to 1: 100, preferably from 2000: 1 to 1:50, particularly preferably 300: 1 to 1:20,

(A2) :( B2) in the range from 18000: 1 to 1: 100, preferably from 2000: 1 to 1:50, particularly preferably from 300: 1 to 1:20,

(A2) :( B3) in the range from 3000: 1 to 1: 100, preferably from 2000: 1 to 1:50, particularly preferably from 300: 1 to 1:20,

(A3) :( B1) in the range from 1000: 1 to 1: 1000, preferably from 200: 1 to 1: 500, particularly preferably from 100: 1 to 1: 200,

(A3) :( B2) in the range from 5000: 1 to 1: 1000, preferably from 800: 1 to 1: 500, particularly preferably from 200: 1 to 1: 500, completely preferred 100: 1 to 1: 200,

(A3) :( B3) in the range from 500: 1 to 1: 800, preferably from 200: 1 to 1: 500, particularly preferably from 100: 1 to 1: 200,

(A4) :( B1) in the range from 1000: 1 to 1: 5000, preferably from 200: 1 to 1: 1000, particularly preferably from 100: 1 to 1: 250,

(A4) :( B2) in the range from 10000: 1 to 1: 5000, preferably from 2000: 1 to 1: 1000, particularly preferably from 1000: 1 to 1: 400, completely preferred from 500: 1 to 1: 250,

(A4) :( B3) in the range from 1000: 1 to 1: 2000, preferably from 200: 1 to 1: 1000, particularly preferably from 100: 1 to 1: 250,

(A5) :( B1) in the range from 1500: 1 to 1: 1000, preferably from 1000: 1 to 1: 500, particularly preferably from 200: 1 to 1: 100,

(A5) :( B2) in the range from 10000: 1 to 1: 2000, preferably from 1000: 1 to 1: 500, particularly preferably from 200: 1 to 1: 100,

(A5) :( B3) in the range from 1500: 1 to 1: 1000, preferably from 1000: 1 to 1: 500, particularly preferably from 200: 1 to 1: 100,

(A6) :( B1) in the range from 2000: 1 to 1: 2000, preferably from 1000: 1 to 1: 1000, particularly preferably from 200: 1 to 1: 200,

(A6) :( B2) in the range from 5000: 1 to 1: 2000, preferably from 2000: 1 to 1: 1000, particularly preferably from 200: 1 to 1: 100,

(A6) :( B3) in the range from 1000: 1 to 1: 1000, preferably from 500: 1 to 1: 500, particularly preferably from 100: 1 to 1: 100.

Of particular interest is the use of combinations

(A1.1) + (B.1.1), (A1.1) + (B.1.2), (A1.1) + (B.1.3), (A1.1) + (B.1.4), (A1 .1) + (B.1.5),

(A1.1) + (B.1.6), (A1.1) + (B.1.7), (A1.1) + (B.1.8), (A1.1) + (B.1.9), (A1 .1) + (B.1.10),

(A1.1) + (B.1.11), (A1.1) + (B.1.12), (A1.1) + (B.1,13), (A1.1) + (B.1.14), (A1.1) + (B.1.15), (A1.1) + (B.1.16), (A1.1) + (B.1.17),

(A1.2) + (B.1.1), (A1.2) + (B.1.2), (A1.2) + (B.1.3), (A1.2) + (B.1.4), (A1 .2) + (B.1.5),

(A1.2) + (B.1.6), (A1.2) + (B.1.7), (A1.2) + (B.1.8), (A1.2) + (B.1.9), (A1 .2) + (B.1.10),

(A1.2) + (B.1.11), (A1.2) + (B.1.12), (A1.2) + (B.1.13), (A1.2) + (B.1.14), (A1 .2) + (B.1.15), (A1.2) + (B.1.16), (A1.2) + (B.1.17),

(A1.1) + (B.2.1), (A1.1) + (B.2.2), (A1.1) + (B.2.3), (A1.1) + (B.2.4), (A1 .1) + (B.2.5),

(A1.1) + (B.2.6), (A1.1) + (B.2.7), (A1.1) + (B.2.8), (A1.1) + (B.2.9), (A1 .1) + (B.2.10),

(A1.1) + (B.2.11),

(A1.2) + (B.2.1), (A1.2) + (B.2.2), (A1.2) + (B.2.3), (A1.2) + (B.2.4), (A1 .2) + (B.2.5),

(A1.2) + (B.2.6), (A1.2) + (B.2.7), (A1.2) + (B.2.8), (A1.2) + (B.2.9), (A1 .2) + (B.2.10),

(A1.2) + (B.2.11),

(A1.1) + (B.3.1), (A1.1) + (B.3.2), (A1.1) + (B.3.3), (A1.1) + (B.3.4), (A1 .1) + (B.3.5),

(A1.1) + (B.3.6), (A1.1) + (B.3.7), (A1.1) + (B.3.8), (A1.1) + (B.3.9), (A1 .1) + (B.3.10),

(A1.1) + (B.3.11), (A1.1) + (B.3.12), (A1.1) + (B.3.13),

(A1.2) + (B.3.1), (A1.1) + (B.3.2), (A1.2) + (B.3.3), (A1.2) + (B.3.4), (A1 .2) + (B.3.5).

(A1.2) + (B.3.6), (A1.2) + (B.3.7), (A1.2) + (B.3.8), (A1.2) + (B.3.9), (A1 .2) + (B.3.10),

(A1.2) + (B.3.11), (A1.2) + (B.3.12), (A1.2) + (B.3.13),

(A2.2) + (B.1.1), (A2.2) + (B.1.2), (A2.2) + (B.1.3), (A2.2) + (B.1.4), (A2 .2) + (B.1.5),

(A2.2) + (B.1.6), (A2.2) + (B.1.7), (A2.2) + (B.1.8), (A2.2) + (B.1.9), (A2 .2) + (B.1.10),

(A2.2) + (B.1.11), (A2.2) + (B.1.12), (A2.2) + (B.1.13), (A2.2) + (B.1.14), (A2 .2) + (B.1.15),

(A2.2) + (B.1.16), (A2.2) + (B.1.17),

(A2.2) + (B.2.1), (A2.2) + (B.2.2), (A2.2) + (B.2.3), (A2.2) + (B.2.4), (A2 .2) + (B.2.5),

(A2.2) + (B.2.6), (A2.2) + (B.2.7), (A2.2) + (B.2.8), (A2.2) + (B.2.9), (A2 .2) + (B.2.10),

(A2.2) + (B.2.11),

(A2.2) + (B.3.1), (A2.2) + (B.3.2), (A2.2) + (B.3.3), (A2.2) + (B.3.4), (A2 .2) + (B.3.5),

(A2.2) + (B.3.6), (A2.2) + (B.3.7), (A2.2) + (B.3.8), (A2.2) + (B.3.9), (A2 .2) + (B.3.10),

(A2.2) + (B.3.11), (A2.2) + (B.3.12), (A2.2) + (B.3.13).

In the case of a combination of compound (A) with one or more compounds (BO), we are talking about the definition of a combination of two or more compounds from group (A). Thanks to the broad-spectrum herbicides (A), such a combination is suggested that transgenic plants or mutants are resistant in all directions to different herbicides (A).

Similar resistances in all directions (Kreuz-resistance) are already known for transgenic plants; Wed international application WO-A-98/20144.

In some cases, it makes sense to combine one or more compounds (A) with several compounds (B), preferably from classes (B1), (B2), (B3) and (B4).

In addition, the claimed combinations can be used together with other active substances from the group of preservative substances, fungicides, insecticides and plant growth regulators, or from the group of additives and auxiliary agents conventional for plant protection. Additives are, for example, fertilizers or dyes.

Preferred are herbicidal combinations of one or more compounds (A) with one or more compounds of the group (B1), or (B2), or (B3).

In addition, combinations of herbicides from one or more compounds (A) are preferred, for example (A1.2) + (A2.2), preferably compounds (A) with one or more compounds (B) according to the scheme:

(A) + (B1) + (B2), (A) + (B1) + (B3), (A) + (B2) + (B3).

Moreover, according to the invention, combinations can also be formulated to which one or more other active substances of a different structure [Active substance (C)] are added, such as, for example,

(A) + (B1) + (C), (A) + (B2) + (C) or (A) + (B3) + (C),

(A) + (B1) + (B2) + (C) or (A) + (B1) + (B3) + (C) or (A) + (B2) + (B3) + (C).

For combinations of the latter type of the above with three or more active substances, the preferred conditions are also primarily valid, which are explained below, first of all, for the claimed double combinations, since the claimed double combinations are contained in them, and these combinations are directly related to double combinations.

As the active substance (C), those that have a preservative effect on corn crops are preferred, especially preservative substances which, in combination with herbicides (B), reduce or eliminate the phytotoxic side effect of herbicides in corn plants.

Of particular interest is the claimed use of combinations with one herbicide from group (A), preferably (A1.2) or (A2.2), especially (A1.2), and with one or more herbicides, preferably with one herbicide, from the group

(B1 ’) cyanazine, acetochlor, alachlor, terbutrin, benoxacor, flutiamide, sulcotrione, mesotrione and pentoxamide or

(B2 ’) pendimethalin, iodosulfuron, metosulam, isoxaflutol, metribuzin, cloransulam, flumetsulam and also flrasulam and isoxachlortol or

(B3 ’) bromoxynil, clopiraralide, carfentrazone and Lab271272 and also halosulfuron, diflufenzopur and sulfosulfuron

or herbicides from several groups (B1 ’) - (B3’).

Combinations of the corresponding components (A) with one or more herbicides from the group (B1 ’), (B2’) or (B3 ’) are preferred.

In addition, combinations of (A) + (B1 ’) + (B2’), (A) + (B1 ’) + (B3’) or (A) + (B2 ’) + (B3’) are preferred.

The inventive combinations (= herbicidal agents) exhibit excellent herbicidal action against a wide range of economically important single and dicotyledonous weeds. Hardly eradicated perennial weeds that give sprouts from rhizomes, root stumps or other long-lived organs are also well destroyed with the help of active substances. In this case, it is equivalent whether the substances are used before sowing, before germination (during the period of swelling) or after germination. Preferred is the use in the post-emergence method or in the early period after sowing - before germination.

Separately, it should be called, for example, some representatives of the mono- and dicotyledonous weed flora, which can be controlled using the claimed compounds, while due to the name there should be no restrictions on certain species.

On the part of monocotyledonous weeds, for example, Echinochloa spp., Setaria spp., Digitaria spp., Brachilisia spp., Panicum spp., Agropyron spp.,

species of wild cereals and Sorghum spp., as well as Avena spp., Alopecurus spp., and Sunodon spp., Lolium spp., Phalaris spp., Poa spp., as well as species of Cyperus and Imperata.

For dicotyledonous weeds, the spectrum of action extends to species, for example, Chenopodium spp., Amaranthus spp., Solarium spp., Datura spp., Abutilon spp., Ipomoea spp., Polygonum spp., Xanthium spp., Stellaria spp., Kochia spp. and Viola spp. as well

Chrysanthemum spp., Marticaria spp., Veronica spp., Anthemis spp., Thiaspi spp., Galium spp., Lamium spp., Pharbitis spp., Sida spp., Sinapis spp., Cupsella spp., Cirsium. spp., Convolvulus spp., Rumex and Artemisia.

If the claimed compounds are introduced before germination on the soil surface, then either the seedlings of the germinating weeds are completely suppressed, or the weeds grow to the stage of a sprouted leaf, but then they nevertheless stop growing and finally die off after three to four weeks.

When applying active substances to the green parts of plants according to the post-emergence method, a sharp stop in growth also occurs very quickly after treatment, and weeds stop at the growth stage at the point corresponding to the application time and after a certain time completely die out, and thus the competition of weeds, harmful to cultivated plants, eliminated very early and for a long time.

The claimed herbicidal agents in comparison with the individual preparations are distinguished by a faster onset and longer lasting herbicidal action. The resistance of the active substances to rain in the claimed combinations, as a rule, is sufficient. The gain in weight is especially advantageous: effective and used in combinations dosages of compounds (A) and (B) can be set sufficiently small, and at the same time their effect on the soil is optimal. Thus, their use is possible not only in sensitive cultures, but combinations based on water should be avoided in practice. Due to the claimed combinations of active substances, it becomes possible to significantly reduce the required applied amounts of active substances.

With the combined use of herbicides of type (A) + (B), a superadditive effect is manifested (synergistic effect = synergism). Moreover, the effectiveness of the combination is higher than the effectiveness of the expected total effect of individual herbicides.

Synergistic effects can reduce the amount used, fight a wide range of weeds and herbs, create an opportunity for a faster onset and longer action of herbicides, increase control over weeds with only one or fewer applications, and also expand the time frame for possible use. Partly due to the use of the agent in plant cultures, the amount of harmful ingredients such as nitrogen or butyric acid is also reduced.

The above properties and advantages are necessary in the practical control of weeds in order to free crops from unwanted competitive plants and thereby quantitatively and qualitatively guarantee the crop at the proper level and / or increase it. Thanks to these new combinations, the norms of technical standards regarding the described properties are clearly exceeded.

Despite the fact that the claimed compounds exhibit excellent herbicidal activity against monocotyledonous and dicotyledonous weeds, tolerant or kreuz-tolerant corn plants are only slightly damaged or not damaged at all.

Moreover, the inventive agents show in part excellent properties in controlling growth in corn plants. They intervene in a regulatory manner in their own metabolism of plants and can be used thereby to separate influence on the constituent parts of plants. In addition, they are also suitable for general control and inhibition of unwanted vegetative growth, without the plants dying. Inhibition of vegetative growth plays a large role in many monocotyledonous and dicotyledonous cultures, since the growth can thereby be reduced or can be completely prevented.

Based on its herbicidal and plant growth-regulating properties, the agents are used to control harmful plants in known tolerant or kreuz-tolerant corn crops or in still undeveloped tolerant or genetically modified corn crops. Transgenic plants, as a rule, are distinguished by particularly advantageous properties, so, in addition to resistance to the claimed agents, they possess, for example, resistance to plant diseases or pathogens of plants, such as certain insecticides or microorganisms, for example fungi, bacteria or viruses . Other distinctive properties relate, for example, to fruits (harvest) - to their quantity, quality, storage ability, composition and special ingredients. Thus, transgenic plants with a high oil content or high quality, for example with a different composition of fatty acids in fruits, are known.

The usual ways of obtaining new plants, which, in comparison with previously known, have modified properties, consists, for example, in the classical method of selection and in the production of mutants. Alternatively, new plants with altered properties can be bred using the genetic engineering method (see, for example, European patent applications EP-A-0221044, EP-A-0131624). In many cases, for example, gene-engineering changes in plant cultures have been described to modify starch synthesized in plants (e.g., international applications WO 92/11376, WO 92/14827, WO 91/19806),

- transgenic plant crops that are resistant to other herbicides, for example sulfonylurea (European patent application EP-A-0257993, US patent US-A-5013659),

- transgenic plant cultures with the ability to produce Thuringian toxins (Bt-toxins) that make plants resistant to certain pests (European patent applications EP-A-0142924, EP-A-0193259),

- transgenic plant cultures with a modified composition of fatty acids (international application WO 91/13972).

Numerous molecular biological technologies by which new transgenic plants with altered properties can be obtained are known in principle; see, for example, Sambrook et al., 1989, Molecular Cloning, A Laboratory Manual, 2. Aufl. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY; or Winnacker "Gene und Klone", VCH Weinheim 2. Auflage 1996 or Christou, "Trends in Plant Science" 1 (1996) 423-431).

For such gene-engineering manipulations, nucleic acid molecules can be inserted into plasmids that make mutagenesis or sequence change possible by recombination of DNA sequences. Using the above standard methods, for example, base exchanges can occur, parts of the sequences can be deleted, or natural or synthetic sequences can be added. To bind DNA fragments under each other, adapters or linkers can be attached to the fragments.

Obtaining plant cells with reduced gene product activity can be achieved, for example, by expression of at least one corresponding antisense RNA, one sense RNA to achieve a cosuppressive effect, or expression of at least one appropriately designed ribosome that specifically cleaves transcript of the aforementioned gene product.

For this, DNA molecules can be used, which include the general coding sequence of the gene product, including randomly present flanking sequences, as well as DNA molecules, which include only parts of coding sequencing, while these parts must be long enough to cause an antisense effect in the cells . It is also possible to use DNA sequences that have a high degree of homology to the coding sequences of the gene product, but are not completely identical.

When expressing nucleic acid molecules in plants, the synthesized protein can be localized in any compartment. In order to achieve localization in a particular compartment, coding sequences can be associated, for example, with DNA sequences that guarantee localization in a particular compartment. Similar sequences are known to those skilled in the art (see, for example, Braun et al., EMBO J. 11 (1992), 3219-3227; Wolter et al., Proc. Natl. Acad. Sci. USA 85 (1988), 846-850; Sonnewald et al., Plant J. 1 (1991), 95-106).

Transgenic plant cells can be regenerated by known techniques into whole plants. With transgenic plants, it can be essentially about plants of any kind, that is, about monocotyledonous and dicotyledonous plants.

Thus, transgenic plants can be obtained that exhibit altered properties due to overexpression, suppression or inhibition of homologous (= natural) genes or sequential genes or expression of heterologous (= foreign) genes or gene sequences.

In this regard, the invention also provides a method for controlling undesired plant growth in tolerant crops, characterized in that one or more type (A) herbicides with one or more type (B) herbicides are applied to weeds, parts of these plants or cultivated surface.

The invention also relates to new combinations of compounds (A) + (B) and herbicidal preparations containing these combinations.

The inventive combinations of active substances can also be in the form of mixed formulations of the two components, in some cases with other active substances, additives and / or conventional adjuvants of the formulation, these mixed formulations are then usually diluted with water and used, or the inventive combinations are made in the form of so-called tank (tanker) mixtures by general dilution of separately composed or partially separately composed components.

Compounds (A) and (B), or combinations thereof, can be formulated in various ways depending on which biological or physico-chemical parameters are specified. Common possibilities for the composition are, for example, spraying powder (WP), emulsifiable concentrates (EC), aqueous solutions (SL), emulsions (EW), such as oil-in-water or water-in-oil emulsions ”, Sprayed solutions or emulsions, oil or water based dispersions, suspoemulsions, powder (dust) agents (DP), etchants, granules for application to the soil or for dispersion or water dispersible granules (WP), ULV formulations, microcapsules or waxes.

Certain types of formulations are in principle known and described, for example, in Winnacker-KÜchler, "Chemische Technologie", Band 7, C. Hauser Verlag München, 4. Aufl. 1986; van Valkenburg, "Pesticide Formulations", Marcel Dekker NY, 1973; K. Martens, "Spray Drying Handbook", 3 ^rd Ed. 1979, G. Goodwin Ltd. London

The necessary adjuvants of the compositions, such as inert materials, surfactants, solvents and other additives, are also known and described, for example, in Watkins, "Handbook of Insecticide Dust Diluents and Carriers", 2 ^nd Ed., Darland Books, Caldwell NJ ; HvOlphen, "Introduction to Clay Colloid Chemistry", 2 ^nd Ed., J. Wiley & Sons, NYMarsden, "Solvent guide", 2 ^nd Ed., Interscience, NY 1950; McCutcheon's, "Detergents and Emulsifiers Annual", MC Publ. Corp., Ridegewood NJ; Sisley and Wood, Encyclopedia of Surface Active Agents, Chem. Publ. Co. Inc., NY 1964; Schönfeldt, Grenzflåchenaktive Äthylenoxidaddukte, Wiss. Verlagsgesellschaft, Stuttgard 1976, Winnacker-Küchler, Chemische Technologie, Band 7, C. Hauser Verlag München, 4. Aufl. 1986.

Combinations with other substances with pesticidal activity, such as, for example, other herbicides, fungicides or insecticides, as well as with substances that promote preservation, fertilizers and / or plant growth regulators, for example, in the form of a solid composition, can also be obtained on the basis of these formulations. or tanker (tank) mixture.

Powders for spraying (wettable powders) are uniformly dispersible in water, which, in addition to the active substance, in addition to diluent and inert substance, also contain ionic and nonionic surfactants (wetting agents, dispersants), for example polyoxyethylated alkyl phenols, polyoxyethylated fatty alcohols or fatty amines, alkanesulfonates or alkylbenzenesulfonates, lignin sulfonic acid sodium salt, 2,2'-dinaphthylmethane-6,6'-disulfonic acid sodium salt or oleoylmethyl tauri ovokisly sodium.

Emulsifiable concentrates are obtained by dissolving the active substance in an organic solvent, for example, butanol, cyclohexanone, dimethylformamide, xylene or also in high boiling aromatic compounds or hydrocarbons with the addition of one or more ionic or nonionic surfactants (emulsifiers). As emulsifiers, for example, calcium salts of alkylaryl sulfonic acids, such as calcium dodecylbenzenesulfonate, or nonionic emulsifiers, such as polyglycol fatty acid esters, alkylaryl polyglycol ethers, polyglycol ethers of fatty alcohols, products of condensation of ethylene propylene methylene ethers, ethylene propylene ethers, esters of polyoxyethylene sorbitan fatty acids or polyoxyethylene sorbitan esters.

Powdered agents are obtained by grinding the active substance with finely divided solids, for example talc, natural clays such as kaolin, bentonite and pyrophyllite, or diatomaceous earths.

Granules can be obtained either by spraying the active substance with a nozzle onto an adsorbent granular inert material, or by applying active substance concentrates using adhesive means, for example polyvinyl alcohol, polyacrylic acid sodium salt, or also using mineral oils on the surface of carriers, such as sand, kaolinites, or on the surface of a granular inert material. Suitable active substances can also be granulated in the usual way to obtain fertilizer granules - if desired in a mixture with fertilizers. Water-dispersible granules are obtained, as a rule, by the method of, for example, spray drying, granulation in a vortex layer, plate granulated, mixing in high-speed mixers and extrusion without a solid inert material.

Agrochemical compositions contain, as a rule, from 0.1 to 99 weight percent, in particular from 2 to 95% by weight, of active substances of types A and / or B, and the following concentrations are usually used depending on the type of composition.

In spray powders, the concentration of active substances is, for example, from about 10 to 95 wt.%, The remainder to 100 wt.% Consists of the usual components of the composition. In the case of emulsifiable concentrates, the concentration of active substances may be, for example, from 5 to 80 wt.%. Powdered formulations generally comprise from 5 to 20% by weight of the active substance, spray solutions from approximately 0.2 to 25% by weight of the active substance.

In the case of granules, such as dispersible granules, the content of the active substance depends on whether the active compound is in liquid or solid form and what granulating agents and fillers are used. As a rule, for water-dispersible granules, the active substance content is between 10 and 90% by weight.

Along with this, the above-mentioned formulations with active substances in some cases contain current conventional adhesion improvers, wetting agents, dispersing agents, emulsifiers, preservatives, anti-freezing agents, and solvents, fillers, colorants and carriers, anti-foaming agents, anti-evaporation agents , and agents that affect pH and viscosity.

For example, it is known that the action of ammonium glufosinate (A1.2), as well as its L-enantiomers, can become more effective due to surfactants, preferably due to wetting agents from a number of sulfates of alkyl-polyglycol ethers, which contain, for example, from 10 to 18 carbon atoms, and are used in the form of their salts with alkali metals or ammonium salts, as well as in the form of magnesium salts, for example, such as sodium salts of sulfates of mixed esters of fatty alcohols with diglycols (®Genapol LRO, Hoechst); see European patent applications EP-A-0476555, EP-A-0336151 or US patent US-A-4 400 196, as well as Pr. EWRS Symp. "Factors Affecting Herbicidal Activity and Selectivity", 227-232 (1988). In addition, it is known that sulfates of alkyl polyglycol ethers, as well as penetration enhancing agents and enhancing substances, are suitable for a number of other herbicides, among others also for imidazolinone herbicides, see European patent application EP-A-0502014 .

For use, the usual commercial forms of the present formulations are in some cases diluted in the usual manner, for example, in the case of spray powders, emulsifiable concentrates, dispersions and water-dispersible granules — water. Powder formulations, granules introduced into the soil, and granular granules, as well as spray solutions, are usually not diluted anymore before use with other inert substances.

Active substances can be applied to plants, to parts of plants, to seeds of plants or to cultivated surfaces (arable land), preferably to green plants or parts of plants, and in some cases additionally to arable land.

It is also possible to use, which provides for the joint use of active substances in the form of tank mixtures, while optimally prepared concentrated formulations of the individual active substances are mixed together in a vessel with water, and the resulting spray mixture is used as a herbicidal agent.

The overall herbicidal composition of the inventive combination of the individual active substances (A) and (B) has an advantage in terms of ease of use, since the amounts of the components are already in the correct ratio with each other. In addition, the auxiliary substances in the composition are optimally matched to each other, while the tank mixture of various compositions may contain an undesirable combination of auxiliary substances.

A Examples of formulations of General type

a) A powdery substance is obtained by mixing 10 parts by weight of the active substance / mixture of active substances and 90 parts by weight of talc as an inert substance and grinding the resulting mixture in an impact mill.

c) A wettable, easily dispersible powder in water is obtained by mixing 25 parts by weight of the active substance / mixture of active substances with 64 parts by weight of kaolin-containing quartz as an inert substance, 10 parts by weight of the potassium salt of lignin-sulfonic acid and 1 part by weight of the sodium salt of oleoyl -methyl-tauric acid as a wetting and dispersing agent and grinding the resulting mixture in a core mill.

c) An easily dispersible dispersion concentrate in water is prepared by mixing 20 parts by weight of the active substance / mixture of active substances with 6 parts by weight of alkyl phenol-glycol ether (® Triton X 207), 3 parts by weight of isotridecanol-polyglycol ether (8 EO) and 71 parts by weight of paraffinic mineral oil (boiling range, for example, from about 255 to 277 ° C) and grinding the resulting mixture in a ball mill to a fineness of less than 5 microns.

d) An emulsifiable concentrate is prepared from 15 parts by weight of the active substance / mixture of active substances, 75 parts by weight of cyclohexanone as a solvent and 10 parts by weight of ethoxylated nonylphenol as an emulsifier.

e) Water-dispersible granulate is obtained by mixing

75 parts by weight of the active substance / mixture of active substances,

10 parts by weight of calcium salt of lignin sulfonic acid,

5 parts by weight of sodium lauryl sulfate,

3 parts by weight of polyvinyl alcohol and

7 parts by weight of kaolin,

grinding the resulting mixture in a core mill and granulating the powder in a vortex layer by spraying with water as a granulating liquid.

f) Water-dispersible granules are prepared in such a way that they homogenize

25 parts by weight of the active substance / mixture of active substances,

5 parts by weight of 2,2'-dinaphthylmethane-6,6'-disulfonic acid sodium salt,

2 parts by weight of oleoyl methyl tauric acid sodium salt,

1 part by weight of polyvinyl alcohol,

17 parts by weight of calcium carbonate and

50 parts by weight of water

in a colloid mill and pre-crushed, then grinded in a bead mill, spray the suspension thus obtained in a sprayer using a nozzle and dried.

Biological Examples

1. Impact on weeds before germination

Seeds or processes of rhizomes of monocotyledonous and dicotyledonous weeds are planted in cardboard pots in sandy loamy soil and covered with soil. Tools previously prepared in the form of concentrated aqueous solutions, wettable powders or emulsion concentrates are then applied in the form of an aqueous solution, suspension or emulsion in water, the amount of which is taken at the rate of 600-800 l / ha, in various dosages on the surface of the earth. After processing, the pots are installed in the greenhouse and kept under conditions favorable for weed growth. Visual observation of damage to plants or seedlings (shoots) is carried out after germination of the test plants 3-4 weeks after the start of the experiment in comparison with untreated control plants. As the results of observation show, the claimed agents show high herbicidal efficacy in the pre-emergence period in relation to a wide range of weeds and grasses.

Moreover, often for the claimed combinations there are efficiencies that exceed the formal amount of efficacy when using herbicides separately (= synergistic effect).

When the observed efficacy values exceed the formal sum of the values in experiments in which the active substances are used separately, then they also exceed the expected Colby value, which is calculated by the following formula and is also considered as evidence of synergy (cf. SRColby, in Weeds 15 (1967 ) S.20-22):

E = A + B- (A · B / 100)

In this case, the following notations are used: A, B = Efficiency of active substances A, respectively B in% in (individual experiments) a or b in g AB / ha.

The observed values in the experiments indicate that, at suitable low doses, the effectiveness of the combinations is higher than the expected Colby values.

2. Effect on weeds in the post-emergence period

Seeds or processes of rhizomes of monocotyledonous and dicotyledonous weeds are planted in cardboard pots in sandy loamy soil, covered with soil and germinated in a greenhouse under conditions favorable for growth. Three weeks after planting, the experimental plants at the stage of the third leaf are treated with the claimed means. The inventive means, prepared in the form of powders for spraying or concentrates of emulsions, in various dosages are sprayed with water, the amount of which is taken at the rate of 600-800 l / ha, on the green parts of plants. Approximately 3-4 weeks after the time the experimental plants were in the greenhouse under optimal growth conditions, the effect of the preparations was visually evaluated in comparison with untreated control plants. The inventive funds in the post-emergence period also exhibit high herbicidal activity in relation to a wide range of economically important weeds and weeds.

At the same time, the effectiveness of the claimed combinations is often observed, which exceed the formal amount of efficacy in the application of herbicides separately.

The observed values in the experiments indicate that, at suitable low doses, the efficacy of the combinations are higher than the expected values according to Colby (cf. the estimate in Example 1).

3. Herbicidal action and compatibility with plant cultures (field experience)

Plants of transgenic corn crops with resistance to one or more herbicides (A) were grown together with typical weeds in open ground on 2 × 5 m parcels in natural open ground; alternatively, when growing corn plants, a natural weed overgrowth was established. Processing by the claimed means and separately processing in a control experiment using only one of the components of the active substances was carried out in parallel under standard conditions using a special spraying device (on parcels) at a flow rate of 200-300 liters per hectare according to the scheme from Table 1, i.e. periods before sowing - before germination, after sowing - before germination or after germination at an early, middle or late stage.

Table 1
Application Diagram - Examples The introduction of active substances Before sowing Before germination after sowing After germination 1-2 leaves After germination 2-4 leaves After sprouting 6 sheets Combined (A) + (B) - (A) + (B) - (A) + (B) - (A) + (B) - (A) + (B) Sequential (A) (IN) - (A) (IN) - (A) (IN) - (A) (A) (IN) - (A) (IN) (IN) - (A) (A) + (B) - (IN) (A) - (IN) (A) + (B) - (A) + (B) (A) + (B) - (A) + (B) (A) + (B) (A) + (B) - (A) + (B) (A) + (B) - (A) + (B) (A) + (B) (A) + (B) - (A) + (B) (A) + (B) (A) + (B) (A) + (B) - (A) + (B) (A) + (B) - (A) + (B) (A) + (B) (A) + (B) - (A) + (B) (A) + (B)

At intervals of 2, 4, 6, and 8 weeks after application, the herbicidal efficacy of the active substances or mixtures of active substances was evaluated visually on the treated parcels in comparison with the control untreated parcels. In this case, damage and development of all aerial parts of plants were taken into account. The evaluation was carried out on a percentage scale (100% efficiency = all plants died out; 50% efficiency = 50% of plants and green parts of plants died out; 0% efficiency = no noticeable effect = as on control parcels). In each case, estimates were averaged over 4 parcels.

A comparison showed that the claimed combinations in most cases show greater, and in some cases significantly greater efficacy than the sum of the efficiencies of individual herbicides (E ^A ).

Efficiency over significant lengths of observation time lie above expected Colby values (E ^C ) [cf. explanations in example 1] and therefore indicate synergism. Corn plants, in contrast, are not damaged or are slightly damaged by processing.

Abbreviations used generally in the following tables:

g AB / ha = gram of active substance (100% active substance) per hectare

E ^A = sum of herbicidal efficacy when using herbicides individually

E ^C = expected Colby value (cf. explanation of Table 1)

"Corn LL" = ® Liberty-Link-Mais (corn), which is tolerant or resistant to ammonium glufosinate.

table 2
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha % Damage to Corn LL ³⁾ Herbicidal efficacy ²⁾ (%) against Digitaria sanguinalis Panicum dichotomiflorum (A1.2) 200 2 0 8 400 4 fifteen fifty 600 3 thirty 92 (B.3.2) 300 0 88 0 (A1.2) + (B.3.2) 200 + 300 3 94 (E ^A = 88) 75 (E ^A = 8) 400 + 300 4 100 (E ^C = 89) 92 (E ^A = 50) Abbreviations for table 2:
¹⁾ = Application at the stage of 5-6 sheets
² ) = Observation 11 days after application
³ ) = ® Liberty-Link-Mais = corn that is resistant to ammonium glufosinate,
(A1.2) = Ammonium glufosinate
(B3.2) = Dicamba

Table 3
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ²⁾ (%) against % Damage to LL LL AGRRE SETVI AMARE (A1.2) 200 0 72 65 3 300 0 72 84 2 400 eleven 69 82 5 600 fifteen 69 87 3 1000 74 74 85 4 (B.1.2) 1500 26 53 3 0 (A1.2) + (B1.2) 200 + 1500 32 95 (E ^C = 89) 87 (E ^A = 68) 3 400 + 1500 68 97 (E ^C = 75) 88 (E ^A = 85) 4 Abbreviations for table 3:
¹⁾ = Application at the stage of 2-4 sheets
²⁾ = Observation 3 weeks after application
(A1.2) = Ammonium glufosinate
(B1.2) = Atrazine
AGRRE = Agropyron repens
SETVI = Setaria viridis
AMARE = Amaranthus retroflexus

Table 4
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ² ) (%) against EPHHL % Damage to LL LL (A1.2) 600 55 0 300 45 0 (B1.16) fifty 60 0 100 58 0 150 70 0 (A1.2) + (B1.16) 300 + 50 83 (ЈE ^C 78) 10 300 + 100 95 (E ^C = 77) 10 Abbreviations for table 4:
¹⁾ = Application at stage 4 of the sheet
²⁾ = Observation 6 weeks after application
(A1.2) = Ammonium glufosinate
(B1.16) = Mesotrione
EPHHL = Euphorbia heterophylla

Table 5
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha % Damage to LL LL Herbicidal efficacy ²⁾ % against Euphorbia heterophylla (A1.2) 400 0 60 200 0 fifty 100 0 37 (B1.14) 400 0 75 300 0 68 200 0 60 (A1.2) + (B1.14) 100 + 200 0 99 (E ^A = 97) 400 + 200 0 99 (E ^C = 84) Abbreviations to table 5:
¹⁾ = Application at stage 6 of the sheet
²⁾ = Observation 44 days after application
(A1.2) = Ammonium glufosinate
(B1.14) = Sulcotrione
Table 6
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ¹⁾ (%) against Fagopyron esculentum Lolium multiflorum (A1.2) 500
330
200 55
twenty
10 78
fifteen
0 (B.2.3) 2,5 85 84 (A1.2) + (B.2.3) 330 + 2.5 93 (E ^C - = 88) 90 (E ^C = 87) Abbreviations for table 6:
¹⁾ = application at the stage of 2-4 sheets
² ) = Observation 26 days after application
(A1.2) = Ammonium glufosinate
(B2.3) = Iodosulfuron-methyl
Table 7
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ² ) (%) against Avena fatua Portulaca oleracea (A1.2) 450
300 fifty
48 fifty
43 (B1.5) 1680 40 35 (A1.2) + (B.1.5) 300 + 1680 98 (E ^A = 88) 95 (E ^A = 78) (B.1.1) 2242 35 45 (A1.2) + (B.1.1) 300 + 2242 86 (E ^A = 83) 93 (E ^A = 88) (B.3.1) 360 10 25 (A1.2) + (B.3.1) 300 + 360 63 (E ^A = 58) 65 (E ^A = 60) Abbreviations for table 7:
¹⁾ = Application at the stage of 2-4 sheets
² ) = Observation 28 days after application
(A1.2) = Ammonium glufosinate
(B1.5) = Metolachlor
(B3.1) = Bromoxynil

Table 8
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ² )%) against
Sorghum halepense (A1.2) 500
300 53
fifteen (B1.11) twenty
10 93
62 (A1.2) + (B1.11) 300 + 10 78 (E ^A = 77) Abbreviations for table 8:
¹⁾ = application at stage 4 of the sheet
² ) = Observation 28 days after application
(A1.2) = Ammonium glufosinate
(B1.11) = Primisulfuron-methyl
Table 9
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ² ) (%) against Cassia obtusifolia (A1.2) 400 60 (B.2.1) 925 0 (A1.1) + (B.2.1) 400 + 925 88 (E ^A = 60) Abbreviations for table 9:
¹⁾ = application at stage 3 of the sheet
² ) = Observation 21 days after application
(A1.2) = Ammonium glufosinate
(B2.1) = Pendimethaline

Table 10
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ² ) (%) against Brachiaria plantaginea (A1.2) 600
300
150 70
45
5 (B1.5) 1500 70 (A1.2) + (B1.5) 150 + 1500 95 (E ^A = 75) Abbreviations for table 10:
¹⁾ = application at stage 2 of the sheet
²⁾ = Observation 28 days after application
(A1.2) = Ammonium glufosinate
(B1.5) = Metolachlor
Table 11
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Corn LL Herbicidal efficacy ² ) (%) against Brachiria plantaginea (A1.2) 600 0 82 300 0 63 200 0 60.0 100 0 43 (A3.2) 100 0 73 (A1.2) + (A3.2) ³⁾ 100 + 100 0 92 (E ^A = 86) (B1.6) 1920 0 37 (A1.2) + (B1.6) 100 + 1920 0 83 (E ^A = 80) Abbreviations for table 11:
¹⁾ = application at stage 3 of the sheet
²⁾ = Observation 42 days after application ³⁾ = The second active substance is added 10 days after the first active substance
(A1.2) = Ammonium glufosinate
(A3.2) = Imazetapur
(B1.6) = Alachlor
Table 12
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ² ) (%) against Portulaca oleracea (A1.2) 500 250 60 35 (B3.1) 360 25 (A1.2) + (B3.1) 250 + 360 65 (E ^A = 60) Abbreviations for table 12:
¹⁾ = application at stage 6 of the sheet
² ) = Observation 26 days after application
(A1.2) = Ammonium glufosinate
(B3.1) = Bromoxynil
Table 13
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ²⁾ (%) against Sinapis arvensis (A1.2) 350
230 75
45 (B3.6) fifteen 70 (A1.2) + (B3.6) 230 + 15 99 (E ^C = 85) Abbreviations for table 13:
¹⁾ = Application at the stage of 4-5 sheets
²⁾ = Observation 28 days after application (A1.2) = Ammonium glufosinate
(B3.6) = Tifensulfuron-methyl
Table 14
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Corn LL Herbicidal efficacy ² ) (%) against (A1.2) 400 8 68 200 0 35 (B2.8) 70 8 65 fifty 5 40 (A1.2) + (B2.8) 200 + 50 6 85 (E ^A = 75) (B3.4) 100 0 fifteen (A1.2) + (B3.4) 200 + 100 1 65 (E ^A = 50) Abbreviations for table 14:
¹ ) = application at stage 3 of the sheet
² ) = Observation 21 days after application
(A1.2) = Ammonium glufosinate
(B2.8) = Flumetsulam
(B3.4) = Clopiraralide

Table 15
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ²⁾ (%) against Galium aparine Fagopyrum esculentum (A1.2) 500
250
125 65
45
thirty 55
twenty
10 (B3.8) 60
thirty
fifteen 85
65
45 78
60
thirty (A1.2) + (B3.8) 250 + 15
125 + 30 85 (E ^C = 72)
83 (E ^C = 75) 65 (E ^A = 50)
75 (E ^A = 70) Abbreviations for table 15:
¹⁾ = application at the stage of 3-4 sheets
²⁾ = observation 24 days after application
(A1.2) = Ammonium glufosinate
(B3.8) = Tritosulfuron
Table 16
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal Efficiency) (%) against Sorghum bicolor (B2.5) ¹⁾ one hundred
fifty
25 75
40
twenty (A1.2) ²⁾ 500
250
125 85
fifty
thirty (A1.2) ²⁾ + (B2.5) ¹⁾ 50 + 250
25 + 250 95 (E ^A = 90)
80 (E ^A = 70) Abbreviations for table 16:
¹⁾ = application before germination
² ) = application at stage 4 of the sheet 18 days after application ¹⁾ before germination
³⁾ = observation 46 days after application before germination, respectively, 28 days after the second application after germination
(A1.2) = Ammonium glufosinate
(B2.5) = Isoxaflutol
Table 17
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ²⁾ (%) against Echinochloa crus-galli (A1.2) 500 74 250 45 125 25 (B1.13) 500 55 250 thirty 125 25 (A1.2) + (B1.13) 250 + 125 85 (E ^A = 55) 500 + 125 100 (E ^A = 98) 125 + 500 93 (E ^A = 80) Abbreviations for table 17:
¹⁾ = application at stage 3 of the sheet
² ) = observation 28 days after application
(A1.2) = Ammonium glufosinate
(B1.13) = Flutiamide

Table 18
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ²⁾ (%) against Echinochloa crus-galli (A1.2) 500
250
125 78
65
45 (B1.4) 1500
750
375 45
40
10 (A1.2) + (B1.4) 125 + 750
125 + 1500
500 + 375 93 (E ^A = 85)
97 (E ^A = 90)
92 (E ^{A =} 88) Abbreviations for table 18:
¹⁾ = application at the stage of 3-4 sheets
²⁾ = observation 42 days after application
(A1.2) = Ammonium glufosinate
(B1.4) = Acetochlor
Table 19
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ²⁾ (%) against Lamium amplexicaule (A2.1) 600
400 90
75 (B2.3) 2,5 55 (A2.1) + (B2.3) 400 + 2.5 93 (E ^C = 88) Abbreviations for table 19:
¹⁾ = application at stage 1 sheet
²⁾ = observation 17 days after application
(A2.1) = Isopropylammonium glyphosate
(B2.3) = Iodosulfuron-methyl

Table 20
Herbicidal efficacy in the field experiment on corn Active substance (a) Dose ¹⁾ g AB / ha Herbicidal efficacy ²⁾ (%) against Convolvulus arvensis (A2.1) 400
200 twenty
0 (B3.3) 500 twenty (A1.2) + (B3.3) 400 + 500 50 (E ^A = 40) (B3.9) 500 60 (A1.2) + (B3.9) 200 + 500 75 (E ^A = 60) (B2.2) 900 40 (A1.2) + (B2.2) 200 + 900 73 (E ^A = 40) (B1.12) 900 thirty (A1.2) + (B1.12) 200 + 900 65 (E ^A = 30) Abbreviations for table 20:
¹⁾ = application at the stage of 3-4 sheets
²⁾ = observation 28 days after application
(A2.1) = Isopropylammonium glyphosate
(B3.3) = 2,4-D
(B3.9) = MCPA
(B2.2) = Pyridate
(B1.12) = Dimethenamide

Table 21
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 200 fifty (IN) fifteen 25 (A) + (B) (200 + 15) 81 (50 + 25) Abbreviations for table 21:
²⁾ = Evaluation 22 days after application
(A) = glufosinate
(B) = Tifensulfuron
Table 22
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Chenopodium album (A) 360 fifty (IN) fifteen 0 (A) + (B) (360 + 15) 87 (50 + 0) Abbreviations for table 22:
²⁾ = Evaluation 22 days after application
(A) = Glyphosate
(B) = Tifensulfuron

Table 23
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 200 fifty (IN) 2,5 eighteen (A) + (B) (200 + 2.5) 94 (50 + 18) Abbreviations for table 23:
²⁾ = Evaluation 22 days after application
(A) = glufosinate
(B) = Iodosulfuron
Table 24
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Hordeum vulgare (A) 360 60 (IN) 2,5 fifteen (A) + (B) (200 + 2.5) 88 (60 + 15) Abbreviations for table 24:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Iodosulfuron

Table 25
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Lolium multiflorum (A) 400 0 (IN) fifteen thirty (A) + (B) (400 + 15) 40 (0 + 30) Abbreviations for table 25:
²⁾ = Evaluation 22 days after application
(A) = glufosinate
(B) = Sulfosulfuron
Table 26
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Chenopodium album (A) 360 fifty (IN) fifteen 65 (A) + (B) (360 + 15) 88 (E ^C = 82.5) Abbreviations for table 26:
²⁾ = Evaluation 22 days after application
(A) = Glyphosate
(B) = Sulfosulfuron

Table 27
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 200 45 (IN) 500 17 (A) + (B) (200 + 500) 97 (45 + 17) Abbreviations for table 27:
²⁾ = Evaluation 7 days after application
(A) = glufosinate
(B) = 2.4D
Table 28
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Chenopodium album (A) 360 fifty (IN) 500 79 (A) + (B) (360 + 500) 98 (E ^c = 89) Abbreviations for table 28:
²⁾ = Evaluation 22 days after application
(A) = Glyphosate
(B) = 2.4D

Table 29
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 400 78 (IN) 500 8 (A) + (B) (400 + 500) 97 (78 + 8) Abbreviations for table 29:
²⁾ = Evaluation 7 days after application
(A) = glufosinate
(B) = MCPA
Table 30
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena sativa (A) 360 88 (IN) 500 0 (A) + (B) (360 + 500) 90 (88 + 0) Abbreviations to table 30:
²⁾ = Evaluation 22 days after application
(A) = Glyphosate
(B) = MCPA

Table 31
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Amaranthus retoflexus (A) 200 75 (IN) 60 0 (A) + (B) (200 + 60) 84 (75 + 0) Abbreviations to table 31:
²⁾ = Evaluation 7 days after application
(A) = glufosinate
(B) = Clopiraralide
Table 32
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena sativa (A) 360 88 (IN) 60 0 (A) + (B) (360 + 60) 90 (88 + 0) Abbreviations for table 32:
²⁾ = Evaluation 22 days after application
(A) = Glyphosate
(B) = Clopiraralide

Table 33
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Amaranthus retoflexus (A) 200 75 (IN) 100 eleven (A) + (B) (200 + 100) 89 (75 + 11) Abbreviations for table 33:
²⁾ = Evaluation 7 days after application
(A) = glufosinate
(B) = Bromoxynil
Table 34
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena sativa (A) 360 88 (IN) 100 0 (A) + (B) (360 + 100) 91 (88 + 0) Abbreviations for table 34:
²⁾ = Evaluation 22 days after application
(A) = Glyphosate
(B) = Bromoxynil

Table 35
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Hordeum vulgare (A) 400 70 (IN) 25 0 (A) + (B) (400 + 25) 73 (70 + 0) Abbreviations for table 35:
²⁾ = Evaluation 7 days after application
(A) = glufosinate
(B) = Florasulam
Table 36
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena sativa (A) 360 fifty (IN) 25 0 (A) + (B) (360 + 25) 55 (50 + 0) Abbreviations for table 36:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Florasulam

Table 37
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 200 fifty (IN) 250 25 (A) + (B) (200 + 250) 98 (50 + 25) Abbreviations for table 37:
²⁾ = Evaluation 22 days after application
(A) = glufosinate
(B) = Metribucin
Table 38
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Lolium multiflorum (A) 360 40 (IN) 250 10 (A) + (B) (360 + 250) 50 (E ^C = 46) Abbreviations for table 38:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Metribucin

Table 39
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 200 fifty (IN) 150 25 (A) + (B) (200 + 150) 92 (50 + 25) Abbreviations for table 39:
²⁾ = Evaluation 22 days after application
(A) = glufosinate
(B) = Sulcotrione
Table 40
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena Sativa (A) 360 fifty (IN) 150 0 (A) + (B) (360 + 150) 58 (50 + 0) Abbreviations for table 40:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Sulcotrione

Table 41
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 200 fifty (IN) fifty 25 (A) + (B) (200 + 50) 75 (E ^C = 74) Abbreviations for table 41:
²⁾ = Evaluation 22 days after application
(A) = glufosinate
(B) = Isoxaflutol
Table 42
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Lolium multiflorum (A) 200 twenty (IN) fifty 0 (A) + (B) (200 + 50) 35 (20 + 0) Abbreviations for table 42:
²⁾ = Evaluation ⁷ days after application
(A) = glufosinate
(B) = Isoxaflutol

Table 43
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Hordeum vulgare (A) 360 60 (IN) fifty 0 (A) + (B) (360 + 50) 65 (60 + 0) Abbreviations for table 43:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Isoxaflutol
Table 44
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Lolium multiflorum (A) 400 0 (IN) fifty 35 (A) + (B) (400 + 50) 40 (0 + 35) Abbreviations for table 44:
²⁾ = Evaluation 22 days after application
(A) = glufosinate
(B) = Mesotrione

Table 45
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena sativa (A) 360 40 (IN) fifty 0 (A) + (B) (360 + 50) 55 (40 + 0) Abbreviations for table 45:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Mesotrione
Table 46
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Chenopodium album (A) 400 thirty (IN) fifteen 65 (A) + (B) (400 + 15) 98 (30 + 65) Abbreviations for table 46:
²⁾ = Evaluation 22 days after application
(A) = glufosinate
(B) = Carfentrazone

Table 47
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Chenopodium album (A) 360 fifty (IN) fifteen 65 (A) + (B) (360 + 15) 98 (E ^C = 83) Abbreviations for table 47:
²⁾ = Evaluation 22 days after application
(A) = Glyphosate
(B) = Carfentrazone Table 48
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena sativa (A) 360 fifty (IN) fifteen 0 (A) + (B) (360 + 15) 55 (50 + 0) Abbreviations for table 48:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Carfentrazone

Table 49
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 400 78 (IN) 500 10 (A) + (B) (400 + 500) 90 (78 + 10) Abbreviations for table 49:
²⁾ = Evaluation 7 days after application
(A) = glufosinate
(B) = Pendimethaline
Table 50
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Hordeum vulgare (A) 360 60 (IN) 500 0 (A) + (B) (360 + 500) 63 (60 + 0) Abbreviations to table 50:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Pendimethaline

Table 51
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena sativa (A) 360 88 (IN) 500 10 (A) + (B) (360 + 500) 92 (E ^C = 90) Abbreviations for table 51:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Pendimethaline
Table 52
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Lolium mutliflorum (A) 400 40 (IN) 400 0 (A) + (B) (400 + 400) 55 (40 + 0) Abbreviations for table 52:
²⁾ = Evaluation 7 days after application
(A) = glufosinate
(B) = Flutiamide (Flufenacet)

Table 53
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Avena sativa (A) 360 fifty (IN) 400 0 (A) + (B) (360 + 400) 55 (50 + 0) Abbreviations for table 53:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Flutiamide (Flufenacet)
Table 54
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Trifolium alexandrinum (A) 200 fifty (IN) 750 70 (A) + (B) (200 + 750) 94 (E ^C = 85) Abbreviations to table 54:
²⁾ = Evaluation 7 days after application
(A) = glufosinate
(B) = Isoproturon

Table 55
Herbicidal activity in the field experiment on corn Active substance (s) Dose g AB / ha Herbicidal efficacy ²⁾ (%) with respect to Hordeum vulgare (A) 360 60 (IN) 750 25 (A) + (B) (360 + 750) 87 (60 + 25) Abbreviations for table 55:
²⁾ = Evaluation 7 days after application
(A) = Glyphosate
(B) = Isoproturon

Claims (9)

1. A method of controlling weeds in tolerant corn crops by joint or separate pre-emergence or post-emergence or pre- and post-emergence application of herbicides on plants, parts of plants, seeds of plants or on a cultivated surface, characterized in that they are used as herbicides (A) one or more broad-spectrum herbicides from the group of compounds, which consists of (A1) compounds of formulas (A1)

where Z is a residue of the formula —OH or a peptide residue of the formula —NCHCH (CH ₃ ) CONCHCH (CH ₃ ) COOH or -NCHS (CH ₃ ) CONCHCH [CH ₂ CH (CH ₃ ) ₂ ] COOH, and their esters and salts and other derivatives of phosphinotricin, (A2) compounds of formula (A2) and their esters and salts,

and (B) one or more herbicides from the group of compounds, which consists of (B1) herbicides of the cyanazine, alachlor, nicosulfuron, flutiamide, rimsulfuron, sulcotrione, mesotrione and pentoxamide group of herbicides, (B2) herbicides of the pendimethalin group, metosulam, isoxaflutol, metribuzin, cloransulam, flumetsulam, linuron, florasulam and isoxachlortol; and (B3) herbicides of the bromoxynil group, 2,4-D, chlorpiralide, tifensulfuron, carfentrazone, tritosulfuron (Lab 271272), MCPA, halosulfuron, and sulfosulfuron, in this case, components (A) and (B) are taken in a synergistically effective ratio, and the use of a combination of herbicides that contain a combination of (A1) glufosinate and (B) pendimethalin, nicosulfuron, isoxaflutol, flumetsulam, bromoxynil or clopyralide is excluded from the claims. 2. The method according to claim 1, characterized in that the active substance (A) is ammonium glufosinate. 3. The method according to claim 1, characterized in that as the active substance (A) isopropylammonium glyphosate is used. 4. The method according to one of claims 1 to 3, characterized in that the process is carried out in the presence of auxiliary substances conventional in plant protection. 5. A herbicidal composition containing two herbicides and, if necessary, additives and excipients customary for the herbicidal compositions, characterized in that it contains as herbicides (A) a broad spectrum herbicide of the formula (A1)

where Z is a residue of the formula —OH or a peptide residue of the formula —NCHCH (CH ₃ ) CONCHCH (CH ₃ ) COOH or —NHCH (CH ₃ ) CONHCH [CH ₂ CH (CH ₃ ) ₂ ] COOH, and (B) a herbicide from the group of compounds, which consists of (B1) herbicides of the group of cyanazine, alachlor, rimsulfuron, flutiamide, sulcotrione, mesotrione and pentoxamide, (B2) herbicides of the metosulam, metribuzin, cloransulam, linuron, florasulam and isoxachlortol group herbicides, (B3) herbicides of the 2,4-D group, triphenesulfuron, carfentrazone, tritosulfuron (Lab 271272), MCPA, halosulfuron, and sulfosulfuron, wherein components (A) and (B) are taken in a synergistically effective ratio. 6. A herbicidal composition containing two herbicides and, if necessary, additives and excipients customary for the herbicidal compositions, characterized in that it contains as herbicides (A) a broad spectrum herbicide of the formula (A2)

(B) a herbicide from the group of compounds, which consists of (B1) herbicides of the cyanazine, alachlor, nicosulfuron, rimsulfuron, flutamide, sulcotrione, mesotrione and pentoxamide group of herbicides, (B2) herbicides of the pendimethalin group, metosulam, isoxafluiol, metribuzin, cloransulam, flumetsulam, linuron, florasulam and isoxachlortol (B3) herbicides of the bromoxynil group, 2,4-D, chlorpiralide, tifensulfuron, carfentrazone, tritosulfuron (Lab 271272), MCPA, halosulfuron, diflufenzopyr and sulfosulfuron, while components (A) and (B) are taken in a synergistically effective ratio. Priority on points and signs: 08/13/1998 - according to claim 1, except for the use of component A, which is a compound of general formula (A1) in the form of other phosphinotricin derivatives; 08/13/1998 - according to claims 2-6; 08/10/1999 - according to claim 1, in terms of the use of component A, which is a compound of general formula (A1) in the form of other phosphinotricin derivatives.