MXPA01001651A - Herbicides for tolerant or resistant corn cultures - Google Patents

Abstract

In order to control weeds in corn cultures consisting of tolerant or resistant mutants or transgenic corn plants, herbicide combinations (A) + (B), optionally in the presence of safeners, are particularly suitable, said combinations having an active content of:(A) herbicides exhibiting broad-spectrum effectiveness from group (A1) glufosinate(salts) and allied compounds;(A2) glyphosate(salts) and allied compounds such as sulfosate and (A3) imidazolinones, (A4) herbicidal azoles from the group of protoporphyrinogen oxidase inhibitors (PPO inhibitors) (A5) cyclohexanedion herbicides and (A6) heteroaryloxyphenoxy propionic acid herbicides and (B) one or more herbicides from the group of compounds consisting of (B0) one or more herbicides structurally different from the above-mentioned group (A), or (B1) herbicides exhibiting activity against monocotyledonous and dicotyledonous weeds with an effect on both the foliage and the soil or (B2) herbicides which can be selectively used in corn against dicotyledonous weeds, (B3) herbicides having an effect on both the foliage and the soil and which can be selectively used in corn primarily against dicotyledonous weeds or herbicides from several groups consisting of (B0) to (B3) and the corn cultures exhibiting tolerance in relation to the herbicides (A) and (B), optionally in the presence of safeners, contained in said combination.

Description

HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT CORN CROPS DESCRIPTIVE MEMORY The invention relates to the field of crop protection products that can be used against harmful plants in tolerant or resistant corn crops, and which comprise, as active herbicidal substances, a combination of two or more herbicides. The introduction of tolerant or resistant varieties of corn and maize lines, particularly corn varieties and transgenic maize lines, adds novel active substances that are not selective in conventional corn varieties, to the conventional weed control system . For example, the active substances are known broad-spectrum herbicides such as glyphosate, sulfosate, glufosinate, bialaphos and imidazolinone herbicides [herbicides (A)], which can now be used in the tolerant cultures developed specifically for them. The effectiveness of these herbicides against harmful plants in tolerant crops is high, but depends, in the same way as with other herbicide treatments, on the nature of the herbicide used, the rate of application, the preparation in question, the type of harmful plants which are going to be controlled, the climatic and soil conditions, etc. In addition, herbicides have weak points (the zero effect) against specific species of harmful plants. Another criterion is the duration of its action, or the rate of degradation of the herbicide. Changes in the susceptibility of harmful plants, which may occur with the prolonged use of herbicides or within a geographically limited area, may also be considered. The loss of action against the individual plants can only be compensated to a certain degree by means of application rates of the highest herbicides, if possible. In addition, there is always a demand for methods to achieve the desired herbicidal effect with application rates of more reduced active substances. A lower application rate not only decreases the amount of active substance that is required for its application, but as a rule, also decreases the amount of the formulation aids required. Both advantages reduce the operating expenses and improve the ecological compatibility of the herbicide treatment. One possibility for improving the use profile of a herbicide may be the combination of the active substance with one or more active substances that contribute to the desired additional properties. However, the combined use of a variety of active substances rarely leads to the occurrence of phenomena of physical and biological incompatibility, for example the lack of stability of a co-formulation, the decomposition of an active substance or the antagonism of the active substances. In contrast, what are desired are combinations of active substances with a favorable profile of action, with high stability and with a synergistic action as much as possible, which allows the application rate to be reduced in comparison with the individual application of the substances active that will be combined. Surprisingly, it has been found that the active substances of the group of broad-spectrum herbicides mentioned above (A) in combination with other herbicides of group (A), and if appropriate, specific herbicides (B) interact in a special and favorable manner when they are used in corn crops that are suitable for the selective use of the herbicides that were mentioned at the beginning. Therefore, the invention relates to the use of herbicidal combinations to control harmful plants in corn crops, wherein the combination of herbicides in question has an active synergistic content of: (A) is a broad spectrum herbicide from the group of compounds consisting of: (A1) the compounds of the formula (A1), wherein Z is a radical of formula -OH or a peptide radical of the formula -NHCH (CH3) CONHCH (CH3) COOH or NHCH (CH3) CONHCH [CH2CH (CH3) 2] COOH, as well as their esters and salts, preferably glufosinate and its salts with acids and bases, in particular glufosinate-ammonium, L-glufosinate or its salts, bialaphos and its salts with acids and bases, and other derivatives of phospho-fynothricin, (A2) the compounds of the formula (A2), like his esters and salts, preferably glyphosate and its alkali metal salts or salts with amines, in particular glyphosate isopropylammonium, and sulfosates, (A3) imidazolinones, preferably imazetapyr, imazapyr, imazametabenzo-methyl, imazaquin, imazamox, imazapic (AC 263,222) and their salts, furthermore of (A4) herbicidal azoles of the protoporphyrinogen oxidase inhibitors (PPO inhibitors), such as, WC9717 (= CGA276854), (A5) cyclohexanedione herbicides and, if appropriate, also (A6) heteroaryloxyphenoxypropionic acid herbicides, and ( B) one or more herbicides from the group of compounds consisting of (BO) one or more herbicides of different structures from the aforementioned group (A) and / or (Bl) herbicides that act on the soil or soil that are effective against harmful monocotyledonous and dicotyledonous plants, and / or (B2) herbicides that can be used selectively in corn against dicotyledons, and / or (B3) herbicides that act on the foliage and soil that can be employees selectively in corn, and predominantly against harmful dicotyledonous plants, and corn crops are tolerant to the herbicides (A) and (B) that form a constituent of the combination, and if appropriate in the presence of protectants . "Herbicides d & structure different from the group mentioned above (A)" in the group (BO) only include herbicides that are included in the definition of the group (A), but that are not a component (A) in the combination in question . In addition to the combinations of herbicides according to the invention, other active substances and crop protection adjuvants can be used, as well as formulation aids which are conventionally used in the protection of crops. The synergistic effects are observed when the active substances (A) and (B) are applied in combination, but can also be observed with dispersed application (dispersion). Another possibility is to apply herbicides or combinations of herbicides in various portions (sequential application), for example after pre-emergence applications, followed by post-emergence applications or after early post-emergence applications, followed by medium-term or late applications of post-emergence. The simultaneous application of active substances of the combination in question is preferred, if convenient in various portions. However, it is also possible to perform a stepwise application of the individual active substances of a combination and it may be convenient in certain individual cases. Other crop protection agents such as fungicides, insecticides, acaricides and the like, and / or different applications of auxiliaries, adjuvants and / or fertilizers in this application system can also be integrated. The synergistic effects allow the application rates of the individual active substances to be reduced, a more potent action against the same species of harmful plant combined with the same proportion of application, the control of species to which the action has not yet been extended (zero effect), an extended period of application and / or a reduced number of individual applications required and (as a result for the user) allow weed control systems with greater economic and ecological advantage. For example, the combinations of (A) + (B) according to the invention allow for increased effects in terms of their synergy, which far and unexpectedly exceed the effects that can be achieved with the individual active substances (A) and (B) .

WO-A-98/09525 has hitherto described a method for controlling weeds in transgenic crops which are resistant to phosphorus-containing herbicides, such as glufosinate or glyphosate, which are combinations of herbicides which are employed and which comprise glufosinate or glyphosate and at least one herbicide from the group consisting of prosulfuron, primisulfuron, dicamba, pyridate, dimethenamid, metolachlor, flumeturon, propaquizafop, atrazine, clodinafop, norflurazone, ametryn, terbutylazine, simazine, prometryn, NOA-402989 (3-phenyl- 4-hydroxy-6-chloropyridazine), a compound of formula wherein R = 4-chloro-2-fluoro-5- (methoxycarbonylmethylthio) phenyl which is described in (EU-A-4671819), CGA276854 = 1-allyloxycarbonyl-1-methyl-ethyl-2-chloro-5- (3-methyl) -2,6-dioxo-4-trifluoromethyl-3,6-dihydro-2H-pyrimidin-1-yl) -benzoate (= WC9717 which is described in EU-A-5183492) and 4-oxetanyl-2-. { N- [N- (4,6-dimethylpyrimidin-2-yl) aminocarbonyl] -aminosulfonyl} benzoate (which is described in EP-A-496701). Details on the effects that can be obtained, or the effects that have been obtained can not be found in the publication WO-A-98/0925. There are no examples on the synergistic effects or on the performance of a method on specific crops, nor are there specific combinations of two, three or more herbicides.

DE-A-2856260 has described some combinations of herbicides with glufosinate or L-glufosinate and other herbicides such as alloxydim, linuron, MCPA, 2,4-D, dicamba, triclopir, 2,4, -T, MCPB and others. Some combinations of herbicides with glufosinate or glyphosate and other herbicides of the sulfonylurea series such as metsulfuron-methyl, nicosulfuron, primisulfuron, rimsulfuron and the like have been described in WO-A-92/08353 and EP-A 0 252 237. Without However, the use of combinations to control harmful plants has been shown in publications only with reference to a few plant species or others that are not exemplified. In these experiments, it has surprisingly been found that there are large differences between the usefulness of the combinations of herbicides mentioned in WO-A-98/09525 and in other references as well as in other combinations of novel herbicides in plant crops. According to the invention, combinations of herbicides are provided which can be used particularly conveniently in tolerant corn crops. The compounds of the formulas (A1) to (A5) are known or can be prepared analogously to known processes. Formula (A1) covers all stereoisomers and their mixtures, in particular the racemate and the particular enantiomer having biological action, for example L-glufosinate and its salts. Examples of active substances of the formula (A1) are the following: (A1.1), glufosinate in the strict sense, ie, D, L-2-amino- [hydroxy- (methyl) phosphinyl] butanoic acid, ( A1.2), glufosinate-monoammonium salt, (A1.3) L-glufosinate, L- or (2S) -2-amino-4- [hydroxy (methyl) phosphinyl] butanoic acid (= phosphinothricin), (A1. 4) salt of L-glufosinate monoammonium, (A1.5) bialaphos (or bilanafos), ie L-2-amino-4- [hydroxy (methyl) phosphonyl] butanoyl-L-alanyl-L-alanine, in particular its sodium salt. The aforementioned herbicides (A1.1) to (A1.5) are absorbed through the green parts of the plants and are known as broad-spectrum herbicides, or total herbicides; are inhibitors of the enzyme glutamine synthetase in plants: see "The Pesticide Manual" 11a Edition, British Crop Protection Council 1997, pp. 643-645 and 120-121. Although they can be used after emergence to control broadleaf weeds as well as grass weeds in plantation crops and in non-crop areas and, using specific application techniques, also for treatment in and between rows of agricultural soil crops such as corn, cotton and the like, is increasing the importance of use as selective herbicides in resistant transgenic plant crops. Glufosinate is generally used in the form of a salt, preferably of the ammonium salt. The glufosinate racemate, or glufosinate-ammonium, is generally only applied in proportions between 200 and 2000 g of sa / ha (as = active substance) (= g of ai (active ingredient) / ha = grams of active substance per hectare) . With such proportions, glufosinate is effective mainly when it is absorbed through the green parts of the plants. However, as it degrades in microbial form in the soil in a few days, it has no long-term action in said soil. The same applies to the active substance related sodium bialafos (also called bilanafos-sodium); see "The Pesticide Manual" 11th Edition, British Crop Protection Council 1997, p. 120-121. As a rule, an increasingly less active substance (A1), for example, requires an application rate on the scale of 20 to 800, preferably 20 to 600 grams of glufosinate active substance per hectare (g of sa / ha or g) of ai / ha) in the combinations according to the invention. They also apply similar amounts, preferably quantities that have been converted into moles per hectare, of glufosinate-ammonium and bialaphos, or bialaphos-sodium. Combinations with foliar-acting herbicides (A1) are conveniently employed in corn crops that are resistant or tolerant to the compounds (A1). Some tolerant corn crops that have been genetically engineered are already known and used in practice; see the article in the publication "Zuckerrübe" [Beet], year 47 (1998), p. 217 ff .; for the generation of transgenic plants that are resistant to glufosinate, see EP-A-0242246, EP-A-242236, EP-A-257542, EP-A-275957 and EP-A-0513054. Examples of the compounds (A2) are (A2.1) glyphosate, ie N- (phosphonomethyl) glycine, (A2.2) glyphosate-monoisopropylammonium salt (A2.3) salt of sodium glyphosate (A2.4) sulfosate, ie N- (phosphonomethyl) glycine-trimesium salt = N- (phosphonomethyl) glycine-trimethyisulfoxonium salt Glyphosate is generally used in the form of a salt, preferably of the monoisopropylammonium salt or the trimethyisulfoxonium salt, (= trimesium salt = sulfosate) . Based on glyphosate free acid, the only single dose is on the 0.5-5 kg s.a./ha scale. Glyphosate is similar to glufosinate in relation to certain applications, but in contrast to the previous one, it is an inhibitor of the enzyme 5-enolpiruvilshikimato-3-phosphate synthase in plants; see "The Pesticide Manual" 11th Ed., British Crop Protection Council 1997 pp. 646-649. In the combinations according to the invention, proportions of application on the scale of 200 to 1000, preferably 20 to 800, grams of glyphosate active substance are required as a rule and per hectare. In addition, the tolerant plants generated by genetic engineering for the compounds (A2) are known and have already been introduced in practice; See "Zuckerrübe" year 47 (1998), p. 217 ff .; also see WO 92/00377, EP-A-115673 and EP-A-409815. Examples of imidazolinone (A3) herbicides are (A3.1) imazapyr and its salts and esters, (A3.2) imazetapyr and its salts and esters, (A3.3) imazametabenzo and its salts and esters, (A3.4) imazametabenzo-methyl, (A3.5) imazamox and its salts and esters, (A3.6) imazaquin and its salts and esters, by example, the ammonium salt, (A3.7) mazapic (AC 263.222) and its salts and esters, for example, the ammonium salt. Herbicides inhibit the enzyme acetolactate synthase (ALS) and therefore the synthesis of proteins in plants; they are both active in the soil as well as foliar and, in some cases, show selectivities in crops; see "The Pesticide Manual" 11th Ed., British Crop Protection Council 1997 pp. 697-6999 for (A3.1), pp. 701-703 for (A3.2), pp. 694-696 for (A3.3) and (A3.4), pp. 696-697 for (A3.5), pp. 699-71 for (A3.6) and pp. 5 and 6, revised as AC 263,222 (for A3.7). The application rates of the herbicides are generally between 0.001 and 2 kg of s.a./ha. In combinations according to the invention, they are in the range of 10 to 200 grams of s.a./ha. Combinations with imidazolinone are conveniently employed in corn cultures that are resistant to imidazolines. Such tolerant crops are already known. EP-A-0360750, for example, describes the generation of plants tolerant to the ALS inhibitor by selection methods or genetic engineering methods. The tolerance of the herbicide of the plants is generated by means of an elevated ALS content in the plants. E.U.A. 5,198,599 discloses sulphonylurea- and imidazolinone tolerant plants that have been obtained by screening methods. Examples of PPO inhibitors and (A4) are: (A4.1) piraflufen and its esters, such as pyraflufen-ethyl, (A4.2) carfentrazone and its esters, such as carfentrazone-ethyl, (A4.3) oxadiargyl (A4.4) sulfentrazone (A4.5) WC 9717 or CGA 276854 = 1-allyloxycarbonyl- 1-methylethyl-2-chloro-5- (3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydro-2H-pyrimidin-1-yl) -benzoate (which is described in EU-A- 5183492). The azoles mentioned above are known as inhibitors of the enzyme protoporphyrinogen oxidase (PPO); in plants; see "The Pesticide Manual" 11th Ed., British Crop Protection Council 1997 pp. 14048-1049 for (A4.1), pp. 191-193 for (A4.2), pp. 904-904 for (A4.3) and pp. 1126-1127 for (A4.4). The cultures of tolerant plants have already been described previously. As a rule, the application rates of azoles are in the scale 5 to 200 of s.a./ha. Some plants that are tolerant to PPO inhibitors are already known. Examples of cyclohexanedione herbicides (A5) are: (A5.1) sethoxydim (The Pesticide Manual "11th Ed., Bristish Crop Protection Council 1997 (referred to herein as" PM ", pp 11401-1103), ie: (EZ) -2- (ethoxyiminobutyl) -5- [2- (ethylthio) propyl] -3-hydroxy-cyclohex-2-enone, (A5.2) cycloxydim (MW, pp. 290-291), ie: 2- (1-ethoxyiminobutyl) -3-hydroxy-5-thian-3-yl-cyclohex-2-enone, (A5.3) clethodim (MW, pp.250-251), ie: 2-. {(E ) 1 - [(E) -3-Chloroalyloxyimino] propyl] -5- [2- (ethylthio) -propyl] -3-hydroxycyclohex-2-enone, (A5.4) "clefoxidim" or "BAS 625 H "(see AG Chem New Compound Review, Vol. 17, 199, pp. 26 edited by AGRANOVA) (= 2- [1-2- (4-chlorophenoxy) propoxyimino) butyl] -3-oxo-5-thion-3 -yl-cyclohex-1-inol), (A5.5) tralkoxidim (MW, pp. 1211-1212), ie 2- [1- (ethoxyimino) -propyl] -3-hydroxy-5-mesitylcyclohex-2 -enone.The herbicides inhibit mitosis and therefore the synthesis of fatty acids in plants, in particular, act on the foliage and, in some some cases exhibit selectivities in crops. The proportions of application in the herbicides are generally between 0.25 and 1 kg of s.a./ha. In the combinations according to the invention, they are in the range from 10 to 1000 g of s.a./ha. Combinations with cyclohexanediones are used in a manner applicable to corn crops that are resistant to cyclohexanediones. Such tolerant crops are already known. Example of heteroarylphenoxyphenoxypropionic acid (A6) herbicides are: (A6.1) "fenoxaprop-P" and its esters, such as ethyl ester "fenoxaprop-P-ethyl" (see PM, pp. 519-520 ((R) -2- [4- (6-chlorobenzoxy-yolyl-2-yloxy) -phenoxy] propionic acid and its ethyl ester), also in the form of use of the racemate "fenoxaprop" and its esters, such as ethyl ester, and / or (A6.2) "quizalofop-P" and its esters, such as the ethyl or tefuryl ester (see PM, pp. 1089-1092) ((R) -2 ~ [4- (6-chloroquinoxalin-2-yloxy) phenoxy] propionic acid or its ethyl ester or its tetrahydrofurfuryl ester), also in the form of racemate "quizalofop" and its esters; the specific ester "propaquizafop" (compound A6.3) and / or (A6.3) "propaquizafop" (PM, pp. 1021-1022), 2-isopropylidene-aminooxyethyl ester of quizalofop-P, and / or (A6. 4) "fluazifop-P" and its esters, such as butyl ester (see PM, pp. 556-557) ((R) -2- [4- (5-trifluoromethylpyrid-2-yloxy) -phenoxy] propionic acid or its butyl ester), also in the form of use of the racemate "fluazifop" and its ester, and / or (A6.5) "haloxifop-P" and its esters, such as methyl ester (see PM, pp. 660-663) ((R) -2- [4- (3-chloro-5-trifluoromethylpyrid-2-yloxy) phenoxy] propionic acid or its methyl ester), also in the form of use of the racemate "haloxifop" and its esters, such as methyl or ethotile ester and / or (A6.96) "cihalofop" and its esters, such as butyl ester (PM, p. m297-298) ((R) -2- [4- (4-cyano-2-fluorophenoxy) phenoxy] -propionic acid or its butyl ester and / or (A6.7) "clodinafop" and its esters, such as propargyl ester (MW, pp.251-252) ((R) -2- [4- (5-chloro-3-fluoropyrid-2-yloxy) -phenoxy] propionic acid or propargyl ester The herbicides (A6) are known as inhibitors of fatty acid biosynthesis and are generally used at application rates of 5-500 g of as / ha.The rate of application in the combinations according to the invention may be even lower in some cases, for example 1 to 300 g of sa / ha The combinations with the herbicides (A6) are used in maize crops that are tolerant to herbicides, for example, in practice, where it is also the case of those crops that are tolerant to cyclohexanedione herbicides (A5) Examples of suitable components (B) are compounds of subgroups (B1) to (B4): (B1) herbicides that are not only foliar, but also act an on the ground, and can be employed selectively in maize against grasses and dicots, an example of the following compounds (common name and the reference is provided "The Pesticide Manual" 11th Ed., British Crop Protection Council 1997, abbreviated as "PM"): (B1.1) Ciazine (PM, pp. 280-283), ie, 2 (4-chloro-6-ethyl-amino-1, 3,5-triazin-2-ylamino) -2-methylpropionitrile, (B1.2) atrazine (MW, pp.55-57), ie N-ethyl-N'-isopropyl-6-chloro-2,4 -diamino-1, 3,5-triazine, (B1.3) terbutylazine (MW, pp. 1168-1170), ie, N-ethyl-N'-tert-butyl-6-chloro-2,4-diamino -1,3,5-triazine, (B1.4) acetochlor (MW, pp. 10-12), that is, 2-chloro-N- (ethoxymethyl) -N- (2-ethyl-6-methylphenyl) acetamide , (B1.5) metolachlor (MW, pp. 833-834), i.e., 2-chloro-N- (2-ethyl-6-methylphenyl) -N- (2-methoxy-1-methylethyl) -acetamide, (B1.6) alachlor (PM, pp. 23-24), that is, 2-chloro-N- (2,6-diethyl-phenyl) -N- (methoxymethyl) acetamide, (B1.7) terbutrin (PM , pp. 1170-1172), ie N- (1,1-dimethyl-ethyl) -N'-ethyl-6-methylthio-2,4-diamino-1, 3,5-triazine, (B1.8 ) benoxacor (PM, pp. 102-103), that is, 4-dichloroacetyl-3,4-dihydro-3-methyl-2H-1,4-benzoxazine, (B1.9) nicosulfuron (PM, pp. 877- 879), that is, 2- (4,6-dimethoxy) i-pyrimidin-2-yl) -3- (3-dimethylcarbamoyl-2-pyridyl-sulfonyl) urea, (B1.10) rimsulfuron (PM, pp. 1095-1097), i.e., 1- (4,6-dimeth-oxy-pyrimidin-2-yl) -3- (3-ethylsulfonyl-2-pyridylsulfonyl) -urea, (B1.11) primisulfuron and its esters, such as methyl ester (MW, pp. 997-999), ie, 2- [4,6-bis (difluoromethoxy) -pyrimidin-2-ylcarbamoylsulfamoyl] benzoic acid or its methyl ester, (B1.12) dimethenamid (MW , pp. 409-410), ie 2-chloro-N- (2,4-dimethyl-3-thienyl) -N- (2-methoxy-1-methylethyl) -acetamide, (B1.13) flutiamide (BAY FOE 5043, flufenacet) (MW, pp.82-83), ie, 4'-fluoro-N-isopropyl-2- (5-trifluoromethyl-1, 3,4-thiadiazol-2-yloxy) acetanilide, (B1.14 sulcotrione (PM, pp. 1124-1125), ie 2- (2-chloro-4-mesylbenzoyl) cyclohexane-1,3-dione, (B1.15) simazin (PM, pp.1106-1108), that is, 6-chloro-N, N'-diethyl-2,4-diamino-1, 3,5-triazine, (B1.16) mesotrione, ie 2- (4-mesyl-2-nitrobenzoyl) cycle -hexane-1, 3-dione (ZA1296, see, Weed Science Society of America (WSSA) in Abstracts of WSSA (Abstracts) 1999, Vol. 39, pages 65-66, numbers 130-132), (B1.17) photoxamid, ie, 2-chloro-N- (2-ethoxyethyl) -N- (2-methyl-1-phenyl-1-propenyl) acetamide (TKC-94, known from AG Chem New Compound, Review Vol. 17 ( 1999), EP-A-206 251), and, if the active substances of group (B1) are present as racemic mixtures, preferably also the particular active compounds in the form of the pure or enriched active isomer, (B2) herbicides which can be used selectively in corn against dicot ón ón 937-939), ie N- (l-ethyl-propyl) -2,6-dinitro-3,4-xylidine, (B2.2) pyridate (MW, pp. 1064-1066), ie 6- chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate, (B2.3) yodosulfuron (proposed common name) and, preferably, the methyl ester (see, WO 96/41537), ie 4-iodo-2 acid - (4-methoxy-6-methyl-1, 3,5-triazin-2-yl-carbamoylsulfamoyl) benzoic acid or the methyl ester, which is described in WO-A-92/13845, (B2.4) metosulam (PM , pp. 836-495), ie, 2 ', 6'-dichloro-5,7-dimethoxy-3'-methyl- [1,4] triazolo [1, 5a] pyrimidin-2-sulfonanilide, ( B2.5) isoxaflutole (MW, pp. 737-739), ie, (5-cyclopropyl-4-isoxazolyl) [2- (methylsulfonyl) -4- (trifluoromethyl) -phenyl] methanone, (B2.6) metribuzin (MW, pp. 4-amino-6-tert-butyl-3-methylthio-1, 2,4-triazin-5 (4H) -one, (B2.7) cloransulam and, preferably the methyl ester (MW, p.165), that is, 3-chloro-2- (5-ethoxy-7-fluoro- [1, 2,4] triazolo- [1, 5-c] pyrimidin-2-ylsulfonamido) benzoic acid or its ester methyl, (B2.8) flumetsulam (PM, pp. 5 73-574), ie, 2 \ 6'-dichloro-5-methyl- [1, 2,4] triazolo [1, 5a] pyrimidine-2-sulfonanilide and (B2.9) linuron (MW, pp. . 751-753), that is, 3- (3,4-dichlorophenyl) -1-methoxy-1-methylurea and (B2.10) florasulam, ie N- (2,6-difluorophenyl) -8-fluoro- 5-methoxy-1, 2,4-triazolo [1, 5C] -pyrimidine-2-sulfonamide (DE-570, see, Zeitschrift Pfl. Krankh, PfISchutz, Special Publication XVI, 527-534 81998), (B2 .11) isoxaclortol, ie (4-chloro-2- (methylsulfonyl) phenyl) 5-cyclopropyl-4-isoxazolyl ketone, EP-A-470856) and, if the above-mentioned active substances of group (B2) exist as racemic mixtures, preferably also the particular active substance in the form of the pure isomer or effective enriched, (B3) herbicides with foliar action and acting on the soil and which can be used selectively in corn, predominantly against harmful dicotyledonous plants, for example the compounds: (B3.1) bromoxynil (MW, pp. 149-151), ie 3,5-dibromo-4-hydroxybenzonitrile, (B3.2) dicamba (MW, pp. 356-357), that is, 3,6-dichloro-o-anisic acid and its salts, (B3.3) 2,4 -D (PM, pp. 323-327), that is, 2,4-dichlorophenoxy acetic acid and its salts and esters, (B3.4) clopyralid (PM, p. 260-263), ie, 3,6-dichloro-2-pyridinecarboxylic acid and its salts and esters, (B3.5) prosulfuron (MW, pp. 1041-1043), ie, 1- (4-methoxy) 6-methyl-I .Sd-triazin ^ -i -S- ^ - IS.SS-trifluoropropy-phenylsulfonylurea, (B3.6) tifensulfuron and its esters, preferably the methyl ester (MW, pp. 1188-1190), that is, 3 - [[[[(4-methoxy-6-methyl-1, 3,5-triazin-2-yl) amino] carbonyl] amino] -sulfonyl] -2-thiophenecarboxylic acid or its methyl ester, ( B3.7) carfentrazone and its salts and esters, preferably the ethyl ester (PM, pp. 191-193), ie 2-chloro-3- [2-chloro-5- (difluoromethyl-4,5-dihydro- 3-methyl-5-oxo-1 H-1, 2,4-triazol-1-yl) -4-fluorophenyl] propionic acid and its ethyl ester, where the combinations with the compound (A4.2) according to the definition they do not constitute combinations of herbicides of different active substances herbicides A and B and therefore they are excepted, (B3.8) Lab271272 (= tritosulfuron, CAS Reg. No. 142469-14-5; see AG Chem New Compound Review, Vol. 17, 1999, p. 24, edited by AGRANOVA), that is, N - [[[4-methoxy-6- (trifluoromethyl) -1, 3,5-triazin-2-yl) amino] -carbonyl] -2- (trifluoromethyl) benzenesulfonamide) , and (B3.9) MCPA (PM, pp. 767-769), ie, (4-chloro-2-methyl-phenoxy) acetic acid, and its salts and esters, (B3.10) halosulfuron and its esters , such as the methyl ester (PM, pp. 657-659), ie, methyl 3-chloro-5- (4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl) -1-methylpiroxampcarboxylate, also in the form of its salt, (B3.11) diflufenzopyr ( BASF 654 00 H) (PM, pp. 81-82), that is, acid 2 { 1- [4- (3,5-difluorophenyl) semi-carbazon] ethyl} nicotinic acid and its salts, (B3.12) sulfosulfuron (PM, pp. 1130-1131), ie 1- (4,6-di-methoxypyrimidin-2-yl) -3- (2-ethylsulphonyl) - [1,2-a] pyridin-3-ylsulfonyl) urea and, if the above-mentioned active substances of group (B3) exist as racemic mixtures, preferably also the particular active compound in the form of the pure or enriched effective isomer. In the case of active substances that are based on carboxylic acids or other active substances that form salts or esters, the specification of the herbicides by the common name of the acid is also intended to cover the salts and esters, preferably the salts and esters commercially available, in particular, the common commercial form of the active substance. The application rates of the herbicides (B) can vary in large amount from herbicide to herbicide. The following proportions are empirical rules: Compounds (BO): 1-3000 g s.a./ha, preferably 5-2000 g s.a./ha (see, Information on the group of compounds (A)). Compounds (B1): 0.1-5000 g sa / ha, preferably 1-5000 g sa / ha, Compounds (B2): 0.1-5000 g sa / ha, preferably 1-3000 g sa / ha Compounds (B3) 0.5 -5000 g sa / ha, preferably 1-3000 g sa / ha The following specific application rates are preferred (in sa / ha): (B1.1) to (B1.8) 100-5000 g, preferably , in particular 300-3500, (B1.9) to (B1.11) 0, 1-120, preferably 1-90, (B1.12) 50-5000, preferably 100-4000, in particular 300-3500 , (B1.13) 100-2000, preferably 200-1500, in particular 300-1200, (B1.14) 50-1000, preferably 100-600, in particular 200-500, (B1.15) 100- 5000, preferably 200-4000, in particular 300-3500, (B1.16) 10-5000, preferably 25-300, in particular 50-200, (B1.17) 5-1500, preferably 10-1000, in particular 20-800, (B2.1) 100-3000, preferably 200-2500, in particular 300-2000, (B2.2) 100-2500, preferably 200-2000, in particular 300-1500, (B2 .3) 0.1-100, preferably 0.2-20, in particular ular 0.5-15, (B2.4) 1 -200, preferably 5-150, in particular 10-100, (B2.5) 5-300, preferably 10-200, in particular 20-150, (B2. 6) 10-1500, preferably 25-1000, in particular 50-800, (B2.7) 2-200, preferably 2.5-100, in particular 5-80, (B2.8) 5-500, preferably 10-300, in particular 20-200, (B2.9) 50-2500, preferably 100-2000, in particular 200-1000, (B2.10) 0.5-100, preferably 1-20, in particular 3-15, (B2.11) 5-300, preferably 10-200, in particular 20-150, (B3.1) 50-1000 , preferably 100-600, in particular 200-500, (B3.2) 5-2500, preferably 10-2000, in particular 200-1500, (B3.3) 50-3000, preferably 100-2000, in particular 200-1500, (B3.4) 10-300, preferably 20-250, in particular 40-200, (B3.5) 1-100, preferably 2-70, in particular 5-50, (B3.6) 0.5-100 , preferably 1-50, in particular 2-40, (B3.7) 1-250, preferably 5-120, in particular 10-100, I (B3.8) 1 -200, preferably 5-150, in particular 10-120 (B3.9) 50-3000, preferably 100-2000, in particular 200-1500, (B3.10) 1-200, preferably 5-150, in particular 10-50 (B3.11) 5-1000, preferably 10-500, in particular 20-80, (B3.12) 1-150, preferably 5-100, in particular 5-80. The proportions of the compounds (A) and (B) can be deduced from the aforementioned application rates for the individual substances, for example the following proportions are of particular interest: (A) :( B) on the 18,000 scale: 1 to 1: 5000, preferably 2000: 1 to 1: 1000, in particular 200: 1 to 1: 100, (A) :( B0) on the scale of 1000: 1 to 1: 400, preferably 400: 1 at 1: 400, in particular 200: 1 to 1: 200, (A1) :( B1) on the scale of 1500: 1 to 1: 300, preferably 400: 1 a 1: 250, in particular 200: 1 to 1: 100, (A1) :( B2) on the scale of 10,000: 1 to 1: 300, preferably 1500: 1 to 1: 250, in particular 1000: 1 to 1 : 100, in particular preferably 200: 1 to 1: 100 (A1) :( B3) on the scale of 2000: 1 to 1: 300, preferably 1500: 1 to 1: 250, in particular 200: 1 to 1 : 100, (A2) :( B1) on the scale of 2500: 1 to 1: 100, preferably 2000: 1 to 1: 150, in particular 300: 1 to 1: 20, (A2) :( B2) in the scale of 18,000: 1 to 1: 100, preferably 2000: 1 to 1: 150, in particular 300: 1 to 1:20, (A2) :( B3) on the scale of 3000: 1 to 1: 100, preferably 2000: 1 to 1:50, in particular 300: 1 to 1:20, (A3) :( B1) on the scale of 1000: 1 to 1: 1000, preferably 200: 1 to 1: 500, in particular 100: 1 to 1: 200, (A3) :( B2) on the scale of 5000: 1 to 1: 1000, preferably 800: 1 to 1: 500, in particular 200: 1 to 1: 500, in particular preferably 100: 1 to 1: 200 (A3) :( B3) on the scale of 500: 1 to 1: 800, preferably 200: 1 to 1: 500, in particular 100: 1 to 1: 200, (A4) :( B1) on the scale of 1000: 1 to 1: 5000, preferably 200: 1 to 1: 1000, in particular 100: 1 to 1: 250, (A4) :( B2) on the scale of 10,000: 1 to 1: 5000, preferably 2000 : 1 to 1: 1000, in particular 1000: 1 to 1: 400, in particular 500: 1 to 1: 250, (A4) :( B3) on the scale of 1000: 1 to 1: 2000, preferably 200: 1 to 1: 1000, in particular 100: 1 to 1: 250, (A5) :( B1) on the scale of 1500: 1 to 1: 1000, preferably 1000: 1 to 1: 500, in particular 200: 1 to 1: 100, (A5) :( B2) on the scale of 10,000: 1 to 1: 2000, preferably 1000: 1 to 1: 500, in particular 200: 1 to 1: 100, (A5) :( B3 ) on the scale of 1500: 1 to 1: 1000, preferably 1000: 1 to 1: 500, in particular 200: 1 to 1: 100, (A6) :( B1) on the 2000 scale: 1 to 1: 2000, preferably 1000: 1 to 1: 1000, in particular 200: 1 to 1: 200, (A6) :( B2) on the scale of 5000: 1 to 1: 2000, preferably 2000: 1 to 1: 1000 , in particular 200: 1 to 1: 100, (A6) :( B3) on the scale of 1000: 1 to 1: 1000, preferably 500: 1 to 1: 500, in particular 100: 1 to 1: 100. The use of the following combinations is of particular interest: (A1.1) + (B1.1), (A1.1) + (B1.2), (A1.1) + (B1.3), (A1. 1) + (B1.4), (A1.1) + (B1.5), (A1.1) + (B1.6), (A1.1) + (B1.1), (A1.1) + (B1.8), (A1.1) + (B1.9), (A1.1) + (B1.10), (A1.1) + (B1.11), (A1.1) + ( B1.12), (A1.1) + (B1.13), (A1.1) + (B1.14), (A1.1) + (B1.15), (A1.1) + (B1. 16), (A1.1) + (B1.17), (A1.2) + (B1.1), (A1.2) + (B1.2), (A1.2) + (B1.3) , (A1.2) + (B1.4), (A1.2) + (B1.5), (A1.2) + (B1.6), (A1.2) + (B1.7), ( A1.2) + (B1.8), (A1.2) + (B1.9), (A1.2) + (B1.10), (A1.2) + (B1.11), (A1. 2) + (B1.12), (A1.2) + (B1.13), (A1.2) + (B1.14), (A1.2) + (B1.15), (A1.2) + (B1.16), (A1.2) + (B1.17), (A1.1) + (B2.1), (A1.1) + (B2.2), (A1.1) + ( B2.3), (A1.1) + (B2.4), (A1.1) + (B2.5), (A1.1) + (B2.6), (A1.1) + (B2. 7), (A1.1) + (B2.8), (A1.1) + (B2.9), (A1.1) + (B2.10), (A1.1) + (B2.11) , (A1.2) + (B2.1), (A1.2) + (B2.2), (A1.2) + (B2.3), (A1.2) + (B2.4), ( A1.2) + (B2.5), (A1.2) + (B2.6), (A1.2) + (B2.7), (A1.2) + (B2.8), (A1. 2) + (B2.9), (A1.2) + (B2.10), (A1.2) + (B2.11), (A1.1) + (B3.1), (A1.1) + (B3.2), (A1.1) + (B3.3), (A1 .1) + (B3.4), (A1.1) + (B3.5), (A1.1) + (B3.6), (A1.1) + (B3.7), (A1.1) + (B3.8), (A1.1) + (B3.9), (A1.1) + (B3.10), (A1.1) + (B3.11), (A1.1) + (B3.12), (A1.1) + (B3.13), (A1.2) + (B3.1), (A1.2), (B3.2), (A1.2) + (B3.3), (A1.2) + (B3.4), (A1 .2) + (B3.5), (A1.2) + (B3.6), (A1.2) + (B3.7), (A1.2) + (B3.8), (A1.2) ) + (B3.9), (A1.2) + (B3.10), (A1.2) + (B3.11), (A1.2) + (B3.12), (A1.2) + (B3.13), (A2.2) + (B1.1), (A2.2) + (B1.2), (A2.2) + (B1.3), (A2.2) + (B1.4), (A2 .2) + (B1.5), (A2.2) + (B1.6), (A2.2) + (B1.7), (A2.2) + (B1.8), (A2.2) ) + (B1.9), (A2.2) + (B1.10), (A2.2) + (B1.11), (A2.2) + (B1.12), (A2.2) + (B1.13), (A2.2) + (B1.14), (A2.2) + (B1.15), (A2.2) + (B1.16), (A2.2) + (B1) .17), (A2.2) + (B2.1), (A2.2) + (B2.2), (A2.2) + (B2.3), (A2.2) + (B2.4) ), (A2.2) + (B2.5), (A2.2) + (B2.6), (A2.2) + (B2.7), (A2.2) + (B2.8), (A2.2) + (B2.9), (A2.2) + (B2.10), (A2.2) + (B2.11), (A2.2) + (B3.1), (A2 .2) + (B3.2), (A2.2) + (B3.3), (A2.2) + (B3.4), (A2.2) + (B3.5), (A2.2) ) + (B3.5), (A2.2) + (B3.6), (A2.2) + (B3.7), (A2.2) + (B3.8), (A2.2) + (B3.9), (A2.2) + (B3.10), (A2.2) + (B3.11), (A2.2) + (B3.12), (A2.2) + (B3) .13).

In the case of the combination of a compound (A) with one or more compounds (BO), that is, according to the definition, a combination of 2 or more compounds of the group (A). Due to the broad-spectrum herbicides (A), the condition for such combination is that the transgenic plants or mutants show resistance against several herbicides (A). These opposing resistances have already been described in transgenic plants; see WO-A-98/20144. In some separate cases, it may be significant to combine one or more of the compounds (A) with more than one compound (B), preferably between the classes (B1), (B2) and (B3). Furthermore, the combinations according to the invention can be used together with other active substances, for example from the group of protectants, fungicides, insecticides and plant growth regulators, or from the group of additives and formulation aids which are conventionally used in the crop protection. The additives are, for example, fertilizers and colors. The herbicidal combinations of one or more compounds (A) with one or more compounds of the group (B1) or (B2) or (B3) are preferred.

Also preferred are combinations of one or more compounds (A), for example (A1.2) + (A2.2), preferably of a compound (A), with one or more compounds (B) as shown in the scheme : (A) + (B) + (B2), (A) + (B1) + (B3), (A) + (B2) + (B3).

The combinations to which one or more different active substances of a different structure are added [active substances (C)] are also according to the invention, for example: (A) + (B1) + (C), (A) + (B2) + (C) or (A) + (B3) + (C), (A) + (B1) + (B2) + (C) or (A) + (B1) + (B3 (+ (C ) or (A) (B2) + (B3) + (C) Preferred conditions are illustrated hereinafter and also apply to combinations of the last mentioned type, with three or more active substances, particularly applied to two-way combinations according to the invention, mainly when they contain two-way combinations according to the invention. The preferred active substances (C) are those which show a protective effect on the corn crop, specifically protective ones which, in combination with the herbicides (B) reduce or avoid the phytotoxic side effects of the herbicides on the corn plants. The use according to the invention of the combinations with one or more herbicides of group (A), preferably (A1.2) or (A2.2), in particular (A1.2), and with one or more herbicides, preferably a herbicide of the group mentioned hereinafter is also of particular interest: (B1 ') cyanizine, acetochlor, alachlor, terbutrin, benoxacor, fluthiamide, sulcotrione, mesotrione and pentoxamide or (B2') pendimethalin, yodosulfuron , metosulam, isoxaflutol, metribuzin, cloransulam, flumetsulam and also florasulam and isoxaclortol or (B3 ') bromoxynil, clopyralid, carfentrazone and Lab271272, in addition to halosulfuron, diflufenzopyr and sulfosulfuron, or herbicides of more than one of the groups (B1') a (B3 '). The combinations of the particular component (A) with one or more herbicides of the group (B1 '), (B2') or (B3 ') are preferred. In addition, combinations (A) + (B1 ') + (B2'), (A) + (B1 ') +) B3') or (A) + (B2 ') + (B3') are also preferred. The combinations according to the invention (= herbicidal compositions) have an outstanding herbicidal activity against a broad spectrum of economically important monocotyledonous and dicotyledonous harmful plants. The active substances also act efficiently in perennial weeds that produce roots of rhizomes, rhizomes that emit roots or other perennial organs and that are difficult to control. In this context, it is not important if the substances are applied before sowing, prior to emergence or after emergence. Post-emergence application, or early application prior to emergence and after sowing is preferred. Specifically, examples of some representative types of monocotyledonous and dicotyledonous weed flora that can be controlled by the compounds according to the invention can be mentioned, without the enumeration being a restriction to certain species. The examples of weed species on which the herbicidal compositions act efficiently are, among the monocotyledons: Echinochloa spp., Setaria spp., Digitaria spp., Brachiaria spp., Panicum spp., Agropyron spp., Wild forms of cereals. and Sorghum spp., but also Avena spp., Alopecurus spp., and Cynodon spp., Lolium spp., Phalaris spp., Poa spp., and the species Cyperus and Imperata. In the case of dicotyledonous weed species, the spectrum of action extends to species such as, for example, Chenopodium spp., Amaranthus spp., Solanum spp., Datura spp., Abutilon spp., Ipomoea spp., Polygonum spp. ., Xanthium spp., Stellaria spp., Kochia spp. and Viola spp., but also Chrysanthemum spp., Matricaria spp., Veronica spp., Anthemis spp., Thlaspi spp., Galium spp., Lamium spp., Pharbitis spp., Sida spp., Sinapis spp., Cupsella spp. , Cirsium spp., Convolvulus spp., Rumex and Artemisia. If the compounds according to the invention are applied to the soil surface before germination, then the weed seedlings are completely prevented from arising, or the weed grows until it has reached the cotyledon stage but then its growth is stopped, and eventually, after three to four weeks have elapsed, they die completely. If the active substances are applied to the green parts of the plants after emergence, then in the same way the growth stops drastically shortly after the treatment and the weed plants are maintained at the growth stage of the application point, or they die completely after a certain period of time, in order to eliminate competition from the weeds, which is harmful to the crop plants, at a very early stage in terms of time, and in a sustained manner. In comparison with the individual preparations, the herbicidal compositions of the invention are distinguished by their fast-acting and longer-lasting herbicidal action. As a rule, the resistance to watering of the active substances in the combinations according to the invention is very favorable. It is a particular utility that the effective doses of the compounds (A) and (B) used in the combinations can be adjusted to such a low amount that their action in soil is optimal. In this way, it is not only possible to use them in sensitive crops, but the contamination of groundwater is practically avoided. By using the combination of the active compound according to the invention, it is possible to considerably reduce the required application rate of the active compounds. When herbicides of type (A) + (B) are applied together, super additive (= synergistic) effects are observed. This means that the effect in the combinations is stronger than the effects of the individually used herbicides. The synergistic effects allow a reduction of the application rate, the control of a wider spectrum of broadleaf weeds and weeds, a faster appearance of the herbicidal action, a longer duration of action, a better control of the plants harmful with only one or a few applications and a possible extension of the period of use. In some cases, the absorption of the compositions also reduces the amount of harmful ingredients in the crop plant, such as nitrogen or oleic acid. The aforementioned properties and advantages are necessary in the practical control of weeds to keep agricultural crops free of undesirable competing plants and in this way ensure and / or increase the quality and quantity of the productions. With respect to the properties described, the prior art is considerably outweighed by these novel combinations. Although the compounds according to the invention have excellent herbicidal activity against monocotyledonous and dicotyledonous weeds, the tolerant or cross-tolerance corn plants do not suffer damage, or in any case suffer damage to a lesser degree. Furthermore, some substances in accordance with The invention has outstanding growth regulating properties in corn plants. These are related to the metabolism of the plant in a regulatory manner and can thus be used for the specific control of the effects on the constituents of the plant. In addition, they are also suitable for regulating and generally inhibiting unwanted vegetative growth, without destroying the plants in the process. The inhibition of vegetative growth plays an important role in many monocotyledonous and dicotyledonous crops, since lodging can be reduced, or completely avoided.

Due to their herbicidal and plant growth regulating properties, the compositions can be used to control harmful plants in corn crops that are known to be tolerant or cross-tolerant or in tolerant or genetically engineered corn crops yet to be grown. Transgenic plants are generally distinguished by having particular, favorable properties, in addition to the resistance to the substances according to the invention, for example the resistance to diseases or of plants or to pathogenic organisms causing plant diseases, such as certain insects or microorganisms such as fungi, bacteria or viruses. Other particular properties relate, for example, to the quantity, quality, storage stability, composition and specific constituents of the harvested product. Thus, transgenic plants having an increased oil content or a modified quality of the oil are known, for example in cases where the harvested product has a different fatty acid composition. Conventional methods for generating novel plants having modified properties compared to plants known to date comprise, for example, traditional methods of cultivation and the generation of mutants. Alternatively, novel plants having modified properties can be generated with the aid of genetic engineering methods (see for example EP-A-0221044, EP-A-0131624). For example, what is shown below has been described in several cases: modification, by genetic engineering, of the crop plants in order to modify the starch synthesized in the plants (for example WO 92/11376, WO 92/14827, WO 91/19806), transgenic crop plants that are resistant to other herbicides, for example sulfonylureas (EP-A-0257993, US-A-5013659), transgenic crop plants that have the ability to produce toxins Bacillus tuhuringiensis (Bt toxins) ) which make plants resistant against certain pests EP-A-0142924, EP-A-0193259), transgenic crop plants having a modified fatty acid composition (WO 91/13972). Numerous molecular biology techniques that allow the generation of new transgenic plants with modified properties are known in principle; see for example, Sambrook et al., 1989, Molecular Cloning, A Laboratory Manual, [Molecular cloning, laboratory manual] 2nd edition. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY; or Winnacker "Gene und Klone" [Genes and Clones], VCH Weinheim, 2nd edition 1996, or Christou, "Trends in Plant Science" [Trends in plant science] 1 (1996) 423-431. In order to carry out such genetic engineering manipulations, it is possible to introduce nucleic acid molecules into plasmids, which allows for mutagenesis or changes in the sequences that occurs by the recombination of the DNA sequences. For example, using the standard procedures mentioned above it is possible to make base changes, remove partial sequences or add synthetic or natural sequences. To link the DNA fragments together, it is possible to fit adapters or linkers to the fragments. For example, the generation of plant cells with a reduced activity of a gene product can be achieved by the expression of at least one antisense RNA, a corresponding sense RNA, to achieve a cosuppression effect, or by expressing at least one ribosome appropriately constructed that specifically cuts the transcripts of the aforementioned gene product. Up to this point, it is possible to use both the molecules of DNA comprising the entire coding sequence of a gene product including any flanking sequence that may be present, and DNA molecules comprising only portions of the coding sequence, these portions being necessary to be long enough to exhibit an effect antisense in the cells. It is also possible to use DNA sequences which have a high degree of homology with the coding sequences of a gene product but which are not completely identical. By expressing nucleic acid molecules in plants, the synthesized protein can be located in any desired cell compartment of the plant. However, to achieve location in a particular compartment it is possible, for example, to link the coding region with the DNA sequences, which ensures localization in a particular compartment. Such sequences are known to those skilled in the art (see, for example, Braun et al., EMBO J. 11 (1992), 3219-3227.; Wolter et al., Proc. Nati Acad. Sci. E.U.A. 5 (1988), 846-850; Sonnewald et al., Plant J. 1 (1991), 95-106). The cells of transgenic plants can be regenerated by known techniques to produce whole plants. The transgenic plants can, in principle, be plants of any desired plant species, ie monocotyledonous or dicotyledonous plants. In this way, it is possible to obtain transgenic plants that have modified properties by overexpression, suppression or inhibition of homologous genes (= natural) or gene sequences or by expression of heterologous genes (= external) or gene sequences. Thus the invention also provides a method for controlling undesirable vegetation in tolerant corn crops, which comprises applying one or more type (A) herbicides with one or more type (B) herbicides to the harmful plants, parts thereof or in the cultivation area. The invention also relates to the use of novel combinations of compounds (A) + (B) and to the compositions containing them. The combinations of the active substance according to the invention can be present in combined formulations of the two components, if appropriate with other active substances, additives and / or traditional formulation aids, which are applied in the customary manner after being diluted in water, or, prepared as the so-called tank mixtures by joint dilution of the components completely or partially formulated with water. The compounds (A) and (B) or their combinations can be formulated in various ways depending on the prevailing biological or physicochemical parameters. Following are examples of general options for formulations: wettable powders (WP), emulsifiable concentrates (EC), aqueous solutions (SL), emulsions (EW) such as oil-in-water and water-in-oil emulsions, sprayable solutions or emulsions, dispersions base oil or water, suspension emulsions, powders (DP), seed protection compositions, granules for dissemination or application in soil, or granules for dispersion in water (WG), ULV formulations, microcapsules or waxes. The types of individual formulations are known in principle and are described, for example in Winnacker-Küchler, "Chemische Technologie" [Chemical Engineering], Volume 7, C. Hauser Verlag Munich, 4th Edition 1986; van Valkenburg, "Pesticides Formulations", Marcel Dekker, N.Y., 1973; K.

Martens, "Spray Drying Handbook", 3rd Edition, 1979, G. Goodwin Ltd.

London. The necessary formulation aids, such as inert materials; Surfactants, solvents and other additives are also known and described for example in Watkins, "Handbook of Insecticide Dust Diluents and Carriers ", 2nd Edition, Darland Books, Caldwell N.J., H.v.

Olphen, "Introduction to Clay Colloid Chemistry"; 2nd Edition, J. Wiley & Sons, N.Y .; Marsden, "Solvents Guide"; 2nd Edition., Interscience, N.Y. 1950; McCutcheon's "Detergents and Emulsors Annual", MC Publ. Corp., Ridgewood N.J .; Sisley and Wood, "Encyclopedia of Surface Active Agents", Chem. Publ. Co. Inc., N.Y. 1964; Schonfeldt, "Grenzfláchenaktive Athylenoxidaddukte" [Ethylene oxide surfactant adducts], Wiss. Verlagsgesellschaft, Stuttgart 1976; Winnacker-Küchler, "Chemische Technologie" [Chemical Technology], Volume 7, C. Hauser Verlag Munich, 4th Edition 1986. Based on these formulations it is also possible to produce combinations with other substances of pesticidal activity, such as other herbicides, fungicides or insecticides, and also with protectants, fertilizers and / or growth regulators, for example in the form of a ready mix or tank mixture. Wettable powders (sprayable powders) are products that can be uniformly dispersed in water and contain, in addition to the active compound, ionic or nonionic surfactants (wetting agents, dispersants), for example polyethoxylated alkylphenols, polyethoxylated fatty alcohols or polyethoxylated fatty amines, alkanesulfonates or alkylbenzene sulphonates, sodium lignosulfonate, sodium 2,2'-dinaphthylmethane-6,6'-di-sulfonate, sodium dibutylnaphthalene sulfonate or also sodium oleoylmethyltaurinate, in addition to an inert material or diluent. The emulsifiable concentrates are prepared by dissolving the active substance in an organic solvent, for example butanol, cyclohexanone, dimethylformamide, xylene or other relatively high boiling aromatic compounds or hydrocarbons with the addition of one or more ionic or nonionic surfactants (emulsifiers). Some examples of emulsifiers that can be used are: calcium salts of alkylarylsulfonic acids, such as calcium dodecylbenzenesulfonate, or nonionic emulsifiers, such as fatty acid polyglycol esters, alkylaryl polyglycol ethers, polyglycol fatty alcohol ethers, propylene oxide condensation products / ethylene oxide, alkyl polyethers, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters or polyoxyethylene sorbitol esters. The powders are obtained by grinding the active substance with finely divided solid materials, for example talc, natural clays such as kaolin, bentonite and pyrophyllite, or diatomaceous earth. The granules can be prepared either by sprinkling the active substance in granular absorbent inert material or by applying concentrates of the active substance to the surface of vehicles such as sand, caoliths or granulated inert material, with the aid of binders, for example polyvinyl alcohol, polyacrylate sodium or other mineral oils. Suitable active substances can also be granulated in the customary manner used to prepare fertilizer granules, if desired as a mixture with fertilizers. The granules which can be dispersed in water are prepared by processes such as spray drying, fluidized bed granulation, disc granulation, mixing using high speed mixers, and extrusion without solid inert material.

The agrochemical preparations generally contain from 0.1 to 99% by weight, in particular from 2 to 95% by weight, of active substances type A and / or B, the following concentrations being customary, depending on the type of formulations: In wettable powders the concentration of the active substance is, for example, approximately 10 to 95% by weight, the remainder to 100% by weight being formed by the customary constituents of the formulation. In emulsifiable concentrates the concentration of the active substance can be, for example, from 5 to 80% by weight. The formulations in the form of powders contain, in most cases, from 5 to 20% by weight of the active substance, while the sprayable solutions contain from about 0.2 to 25% by weight of the active substance. In the case of granules, such as granules that can be dispersed, the content of the active substance depends in part on whether the active compound is liquid or solid and on the granulation auxiliaries and fillers that are used. In granules that can be dispersed in water the content is generally between 10 and 90% by weight. In addition, the aforementioned active substance formulations may comprise, if appropriate, conventional adhesives, wetting agents, dispersants, emulsifiers, preservatives, antifreeze agents, solvents, fillers, colorants, vehicles, antifoams, evaporation inhibitors and pH regulators and regulators. viscosity.

For example, it is known that the effect of glufosinate-ammonium (A1.2) and that of its L-enantiomer can be improved by surfactants, preferably by wetting agents of the alkyl polyglycol ether sulfate series containing, for example, 10 a 18 carbon atoms and which are used in the form of their alkali metal salts or ammonium salts, but also as the magnesium salt, as the diglycol ether sulphite of sodium C? 2-C-? 4 fatty alcohol ( © Genapol LRO, Hoechst); see for example, EP-A-0476555, EP-A-0048436, EP-A-0336151 or US-A-4,400,196 and Proc. EWRS Symp. "Factors Affecting Herbicidal Activity and Selectivity", 227-232 (1988). In addition, it is known that polyglycol ether sulfates are also suitable as penetrants and synergists for a number of different herbicides, including also herbicides of the imidazolinone series; see EP-A-0502014. For use, the formulations, which are commercially available, are optionally diluted in the conventional manner, for example using water in the case of wettable powders, emulsifiable concentrates, dispersions and granules that can be dispersed in water. Preparations in the form of powders, granules for soil, granules for spreading and sprayable solutions are generally not further diluted with other inert substances before use. The active substances can be applied to the plants, parts of the plants, seeds of the plants or the cultivated area (tilled land), preferably to the green plants and parts of the plants and, if desired, in addition to the tilled land. One possible use is the joint application of active substances in the form of tank mixes, the concentrated formulations of the individual active substances, in optimal formulations, they are mixed together with water in the tank, and the obtained spray mixture is applied. A joint herbicidal formulation of the combination according to the invention of the active compounds (A) and (B) has the advantage that it can be applied more easily because the amounts of the components have already adjusted to each other in the correct proportion. In addition, formulation auxiliaries may be selected to suit each other in the best possible manner, while a tank mixture of different formulations may result in undesirable combinations of auxiliaries.

A. Examples of general formulation a) A powder is obtained by mixing 10 parts by weight of a mixture of active substance / active substance and 90 parts by weight of talc as an inert substance and pulverizing the mixture in a hammer mill. b) A wettable powder easily dispersible in water is obtained by mixing 25 parts by weight of a mixture of active substance / active substance, 64 parts by weight of quartz with content of kaolin as an inert substance, 10 parts by weight of potassium lignosulfonate and 1 part by weight of sodium oleoylmethyltaurinate as a wetting and dispersing agent, and the mixture is ground in an articulated disc mill. c) A dispersion concentrate which is readily dispersible in water is obtained by mixing 20 parts by weight of a mixture of active substance / active substance with 6 parts by weight of alkylphenol polyglycol ether (®Triton X 207), 3 parts by weight of isotridecanol polyglycol ether (8 EO) and 71 parts by weight of paraffinic mineral oil (boiling scale of approximately 255 to 277 ° C) and the mixture is milled in a ball mill until a fineness of less than 5 microns is obtained. d) An emulsifiable concentrate is obtained from 15 parts by weight of a mixture of active substance / active substance, 75 parts by weight of ciciohexanone as solvent and 10 parts by weight of ethoxylated nonylphenol as an emulsifier. e) The water-dispersible granules are obtained by mixing 75 parts by weight of a mixture of active substance / active substance, 10 parts by weight of calcium lingosulfonate, 5 parts by weight of sodium lauryl sulfate, 3 parts by weight of polyvinyl alcohol and 7 parts by weight of kaolin, the mixture is ground in an articulated disc mill and the powder is granulated in a fluidized bed by spraying water on it as a granulation liquid. f) Water-dispersible granules are also obtained by homogenizing and pre-pulping, in a colloidal mill, 25 parts by weight of a mixture of active substance / active substance, 5 parts by weight of 2,2'-dinaphthylmethane-β-β-disulfonate of sodium, 2 parts by weight of sodium oleoylmethyltaurinate, 1 part by weight of polyvinyl alcohol, 17 parts by weight of calcium carbonate and 50 parts by weight of water, subsequently grinding the mixture in a sphere mill and atomizing and drying the resulting suspension in a spray tower by means of a model of a single substance.

B. Biological examples 1. Pre-emergence effect on weeds Seeds or rhizome pieces of monocotyledonous and dicotyledonous weed plants are placed in sandy clay soil in plastic pots and covered with soil. The compositions, formulated in the form of concentrated aqueous solutions, wettable powders or emulsion concentrates, are applied to the surface of the soil layer as an aqueous solution, suspension or emulsion at an application rate of 600 to 800 I of water / ha ( converted), in several doses. After the treatment, the pots are placed in a greenhouse and kept under good growing conditions for the weeds. After the test plants have emerged, the damage to the plants or the negative effects on emergence is recorded visually after a test period of 3 to 4 weeks by comparison with the controls without treatment. As the results of the tests show, the compositions according to the invention have good herbicidal activity prior to emergence against a broad spectrum of weed grasses and dicotyledonous weeds. It is often observed that the effects of the combinations according to the invention exceed the formal total of the effects by applying the herbicides individually (= synergistic effects). If the observed effects data already exceed the total formal data of the experiments in individual applications, then they also exceed the expected value in accordance with Colby, which is calculated by the formula below and which is also considered to suggest synergy (see SR Colby; in Weeds 15 (1967) pages 20 to 22); E = A + B- (A-B / 100) A, B demonstrate the effect of the active substances A, or in% for a or b g of s.a./ha; E denotes the expected value in% for a + b g s.a./ha. In appropriately low dosages, the observed data from the experiments show an effect of the combinations on the expected values according to Colby. 2. Post-emergence effect on weeds Seeds or pieces of monocotyledonous and dicotyledonous weed rhizomes are placed in sandy clay soil in cardboard pots, covered with soil and grown in a greenhouse under good growth conditions. Three weeks after sowing the test plants are treated in the three-leaf stage with the compositions according to the invention. The compositions according to the invention, formulated as wettable powders or emulsion concentrates, are sprayed in several doses, on the green parts of the plants and at an application rate of 600 to 800 liters of water / ha (converted). After the test plants have been in the greenhouse for approximately three to four weeks under ideal growth conditions, the effect of the products is recorded visually by comparison with the controls without treatment. The compositions according to the invention also have a good post-emergence herbicidal activity against a broad spectrum of economically important weed grasses and broadleaf weeds. It is often observed that the effects of the combinations according to the invention exceed the formal total of the effects when the herbicides are applied individually. The observed results of the tests show, in suitably low doses, an effect in the combinations that exceed the expected values according to Colby (see the figures recorded in example 1). 3. Herbicidal effect and tolerance of crop plants (field trials) Transgenic maize plants with resistance to one or more herbicides (A) were grown together with typical weed plants outdoors in 2 x 5 m plots, in low open air natural environmental conditions; alternatively, weed infestation occurred naturally when corn plants were grown. The treatment with the compositions according to the invention was carried out under normal conditions, and as a separate control only when applying the active substances of the components with a field sprayer at an application rate of 200 to 300 liters of water per hectare in parallel tests as can be seen in the diagram shown in the table 1, that is, prior to sowing prior to emergence, after sowing, prior to emergence or after emergence in the early, middle or late stages.TABLE 1 Examples of the scheme of use The herbicidal activity of the active substances or mixtures of active substances was visually recorded at 2, 4, 6 and 8 weeks after application with reference to the treated fields compared to the control fields without treatment. Damage and development of all aerial parts of the plants was recorded. The record was made on the basis of a percentage scale (100% action = all plants destroyed, 50% action = 50% of the plants and green parts of the plants destroyed, 0% action = no perceptible effect = equal to the control field The average of the values recorded in each case was calculated by 4 fields The comparison showed that the herbicidal effect of the combinations according to the invention was usually greater, in some cases considerably higher than the total of the Effects of individual herbicides (= EA) In the essential periods of the record period, the effects were greater than the expected values in accordance with Colby (= EC) (see record in example 1) and therefore suggest a synergy. In contrast, the corn plants were not damaged due to treatments with the herbicidal compositions or were only damaged to an insignificant degree. Results of other tests were collected in the tables below. The abbreviations that were used in general in the tables are: g of s.a./ha = gram of active substance (active substance to 100%) per hectare) EA = Total of herbicidal effects in individual applications Ec = Expected value according to Colby (see the record in table 1) "Mais LL" = ® Liberty-Link-Mais, maize tolerant or resistant to glufosinate-ammonium.

TABLE 2 Herbicidal effect in field trials with corn Abbreviations for Table 2: 1) = Application in the 5-6-sheet stage 2) = Registration 11 days after the application 3) = ® Liberty-Link-Mais = corn that is resistant to glufosinate-ammonium, (A1. 2) = glufosinate-ammonium (B3.2) = dicamba TABLE 3 Herbicide effect in field trials with corn Abbreviations for table 3: 1) = Application in the 2-4 sheet stage 2) = Registration 3 weeks after the application (A1.2) = glufosinate-ammonium (B1.2) = atrazine TABLE 4 Herbicidal effect in field trials with corn Abbreviations for table 4: 1 > = Application in the 4-leaf stage 2) = Registration 6 weeks after the application (A1.2) = glufosinate-ammonium (B1.16) = mesotrione EPHHL = Euphorbia heterophylla BLOCKS Herbicide effect in field trials with corn Abbreviations for table 5: 1) = Application in the 6-sheet stage 2) = Registration 44 days after the application (A1.2) = glufosinate-ammonium (A1.14) = sulcotrione TABLE 6 Herbicidal effect in field trials with corn Abbreviations for table 6: 1) = Application in the stage of 2- 4 sheets 2) = Record 26 days after the application (A1.2) = glufosinate-ammonium (B2.3) = yodosulfuron-methyl.

BLOCK Herbicidal effect in field trials with corn Abbreviations for table 7: 1) = Application in the stage of 2- 4 sheets 2) = Record 28 days after the application (A1.2) = glufosinate-ammonium (B1.5) = metolachlor (B3.1) = bromoxinila TABLE 8 Herbicidal effect in field trials with corn Abbreviations for table 8: 1) = Application in the 4-leaf stage 2) = Record 28 days after the application (A1.2) = glufosinate-ammonium (B1.11) = primisulfuron-methyl TABLE 9 Herbicidal effect in field trials with corn Abbreviations for table 9: 1) = Application in the 3-sheet stage 2) = Registration 21 days after the application (A1.2) = glufosinate-ammonium (B2.1) = pendimethalin TABLE 10 Herbicide effect in field trials with corn Abbreviations for table 10: 1) = Application in the 2-sheet stage 2) = Registration 28 days after the application (A1.2) = glufosinate-ammonium (B1.5) = metolachlor TABLE 11 Herbicidal effect in field trials with corn Abbrtions for table 11: 1) = Application in the 3-leaf stage 2) = Registration 42 days after the application 3) = Second active substance applied 10 days after the first active substance. (A1.2) = glufosinate-ammonium (A3.2) = imazetapir (B1.6) = alachlor TABLE 12 Herbicide effect in field trials with corn Abbrtions for table 12: 1) = Application in the 6-sheet stage 2) = Record 26 days after the application (A1.2) = glufosinate-ammonium (B3.1) = Bromoxynil TABLE 13 Herbicidal effect in field trials with corn Abbrtions for table 13: 1) = Application in the 4- to 5-sheet stage 2) = Record 28 days after the application (A1.2) = glufosinate-ammonium (B3.6) = tifensulfuron-methyl TABLE 14 Herbicidal effect in field trials with corn Abbrtions for table 14: 1) = Application in the 3-leaf stage 2) = Registration 21 days after the application (A1.2) = glufosinate-ammonium (B2.8) = flumetsulam (B3.4) = clopiralid TABLE 15 Herbicidal effect in field trials with corn Abbrtions for table 15: 1) = Application in the stage of 3- 4 sheets 2) = Record 24 days after the application (A1.2) = glufosinate-ammonium (B3.6) = tritosulfuron TABLE 16 Herbicide effect in field trials with corn Abbrtions for table 16: 1 > = Application prior to emergence 2) _ Application in the 4-leaf stage 18 days after the application prior to the emergence of 1) 3) _ Registration 46 days after the application prior to emergence, or 28 days after the application after the application. emergence (B2.5) = isoxaflutola (A1.2) = glufosinate-ammonium TABLE 17 Herbicidal effect in field trials with corn Abbrtions for table 17: 1) = Application in the 3-leaf stage 2) = Registration 28 days after the application (A1.2) = glufosinate-ammonium (B1.13) = flutiamide TABLE 18 Herbicidal effect in field trials with corn Abbrtions for table 18: 1) = Application in the stage of 3- 4 sheets 2) = Record 42 days after the application (A1.2) = glufosinate-ammonium (B1.4) = acetochlor TABLE 19 Herbicidal effect in field trials with corn Abbrtions for table 19: 1) = Application in stage 1-sheets 2) = Record 17 days after application (A1.2) = glyphosinate-isopropylammonium (B2.3) = yodosulfuron-methyl TABLE 20 Herbicidal effect in field trials with corn Abbrtions for table 20: 1) = Application in the stage of 3- 4 sheets 2) = Record 28 days after the application (A1.2) = glyphosate-isopropylammonium (B3.3) = 2,4-D (B3) .9) = MCPA (B2.2) = pyridate (B1.12) = dimethenamid

Claims (7)

NOVELTY OF THE INVENTION CLAIMS

1. - The use of herbicidal combinations to control harmful plants in corn crops, wherein said combination comprises an effective amount of A) one or more of the broad spectrum herbicides of the group consisting of (A1) compounds of the formula (A1), wherein Z is a radical of the formula -OH or a radical peptide of the formula -NHCH (CH3) CONHCH (CH3) COOH or -NHCH (CH3) CONHCH [CH2CH (CH3) 2] COOH, and their esters and salts and other phosphinothricin derivatives, (A2) compounds of the formula (A2) and their esters and salts, O or IIH HoChrN-oHrc-oH (A2 'OH (A3) imidazolinones, (A4) herbicidal azoles of the protoporphyrinogen oxidase inhibitors (PPO inhibitors) and the PPO inhibitor WC9717, and (A5) cyclohexanedione herbicides and ( A6) heteroaryloxyphenoxypropionic acid herbicides, and (B) one or more herbicides of the group of cyanazine, atrazine, terbutylazine, acetochlor, metolachlor, alachlor, terbutrin, benoxacor, nicosulfuron, rimsulfuron, primisulfuron, dimethenamid, flutiamide, sulcotrione, simazine, mesotrione and pentoxamid, (B2) herbicides of the group of pendimethalin, pyridate, iodosulfuron, metosulam, isoxaflutola, metribuzin, cloransulam, flumetsulam, linuron, florasulam and isoxaclortola, and (B3) herbicides of the bromóxinil, dicamba, 2,4-D, clopiralid group , prosulfuron, thifensulfuron, carfentrazone, tritosulfuron (Lab271272), MCPA, halosulfuron, diflufenzopyr and sulfosulfuron and where corn crops tolerate the herbicides (A) and (B) contained in the combination, if appropriate. in the presence of protectors, with the exception of the use of herbicidal combinations comprising a) the combination (A1) glufosinate and (B) atrazine, simazine, terbuthylazine, acetochlor, metolachlor, dicamba, pyridate, pendimethalin, dimethenamid, primisulfuron, prosulfuron, nicosulfuron , iodosulfuron, isoxaflutola, flumetsulam, bromoxynil or clopyralid, b) the combination (A2) glyphosate and (B) atrazine, simazine, terbuthylazine, terbutrin, acetochlor, metolachlor, dicamba, pyridate, dimethenamid, primisulfuron, iodosulfuron and prosulfuron, c) combination (A3) imidazolinone and (B) dicamba, bromoxynil, metolachlor, pyridate, primisulfuron, prosulfuron, nicosulfuron, acetochlor or pendimethalin or the combination (A3) imazametabenz and (B) iodosulfuron, d) (A5) sertoxydim and (B) acetochlor , metolachlor or nicosulfuron.

2. The use as claimed in claim 1, wherein glufosinate-ammonium is used as active substance (A).

3. The use as claimed in claim 1, wherein glyphosate-isopropylammonium is used as active substance (A).

4. The use as claimed in any of claims 1 to 3, wherein the herbicidal combination comprises other active ingredients for the protection of crops.

5. The use as claimed in any of claims 1 to 3, wherein the herbicidal combinations are used in combination with auxiliaries and auxiliaries for the formulation conventionally used in the protection of crops.

6. A method to control harmful plants in tolerant corn crops, which comprises the application of the herbicides of the herbicidal combination, according to one or more of claims 1 to 3, together or separately, prior at emergence, after emergence or before and after emergence to plants, parts of plants, seeds of plants or to the cultivated area.

7. A herbicidal composition comprising a combination of one or more herbicides of group (A), according to any of claims 1 to 3, one or more compounds with herbicidal activity of the group consisting of (B1) herbicides of the group of cyanazine, atrazine, terbutilazine, acetochlor, metolachlor, alachlor, terbutrin, benoxacor, nicosulfuron, rimsulfuron, primisulfuron, dimetexiamid, flutiamide, sulcotrione, mesotrione and pentoxamid, (B2) herbicides of the group pendimethalin, pyridate, iodosulfuron, v metosulam, isoxaflutola, metribuzin, cloransulam, flumetsulam, linuron, 5 florasulam and isoxaclortola and (B3) herbicides of the group of bromoxynil, dicamba, 2,4-D, clopyralid, prosulfuron, thifensulfuron, carfentrazone, tritosulfuron (Lab271272), MCPA, halogensulfuron, diflufenzopyr and sulfosulfuron, with the exception of herbicidal combinations that comprise e) the combination of (A1) glufosinate and (B) atrazine, simazine, terbuthylazine, terbutrin, acetochlor, and 10-metolachlor, dicamba, pyridate, pendimethalin, dimethenamid, primisulfuron, prosulfuron, nicosulfuron, iodosulfuron, isoxaflutola, flumetsulam, bromoxynil, or clopyralid, f) the combination (A2) glyphosate and (B) atrazine, simazine, terbutylazine, terbutrin, acetochlor, metolachlor, dicamba, pyridate, dimethenamide, iodosulfuron and prosulfuron, g) the combination (A3) imidazolinone and (B) 15 dicamba, bromoxilin, metolachlor, pyridate, primisulfuron, nicosulfuron, acetochlor, or pendimethalin, or the combination (A3) mazametabenz and (B) yodosulfuron, h) (A5) and (B) acetochlor, metolachlor or nico sulfur. A - * - J &"" "