RU2241493C1 - Method for producing surgical pseudomonofilament suture material by means of photopolymerization - Google Patents

Abstract

FIELD: medical engineering.

SUBSTANCE: method involves impregnating thread with liquid polymerizable material and drying it. Photopolymerizable material is used as the polymerizable material for impregnating the thread in vacuum at 30-60°C during 2-8 h and drying in vacuum cabin at 30-60°C under 1 atm rarefaction. Then the thread is pulled through installation for treating with ultraviolet radiation of 200-400 nm at speed equal to material polymerization speed. The product is washed in alcohol at 30-60°C during 2-8 h and dried in vacuum cabin at 30-60°C during 2-8 h under 1 atm rarefaction.

EFFECT: high quality of material of no adverse toxic effects.

Description

The invention relates to medicine, namely to surgery.

A lot of inventions are known where they tried to obtain a pseudo-monofilament surgical suture by the method of coating the thread with a polymer, for example SU 4624186/14 1988.12.21, RU 5020313/14 1991.12.29, RU 4807796/14 1990.03.28. In all cases, thermopolymerization was carried out, that is, the thread was passed through a heated chamber, as a result of which polymerization occurred. There are inventions where glues or dissolved polymers in solvents are used as coatings, for example RU C1 2076740, 04/10/97. SU A1 1556684, 04/15/90. US A1 4024871, 03/15/77. WO A1 88/00062, 1/14/88. In the latter cases, curing took place in air at room temperature by evaporation of the solvent. These polymerization methods have a significant drawback, namely: the required polymerization depth is not achieved (60-80% Berlin A.A., Korolev G.V. et al. 1983 Acrylic oligomers and materials based on them.). To achieve a higher polymerization depth, it is necessary to increase the heating temperature, which does not allow the material to be made. An underpolymerized polymer has free radicals that can form new compounds with body tissues and oxygen. The formed new compounds exert local negative reactions, which leads to inflammatory processes and an increase in the healing time.

In this invention, the method of photopolymerization is used for polymerization (Shur A.M. High-molecular compounds. 1968), where a higher degree of polymerization is achieved. A distinctive feature of this method is the high polymerization rate and the absence of free radicals in polymer coatings. This method is used for the manufacture of ophthalmic implants, the service life of which is longer than the average life expectancy of patients (US Pat. No. 2074673, A 61 F9 / 000, US Pat. No. 2132162, A 61 F 2/16).

The technical problem solved by the invention is the development of a method for impregnating a filament with photopolymerizable material and curing it by photopolymerization, which achieves the greatest depth of polymerization.

The technical result of this invention is to obtain a non-toxic pseudomonofilament surgical suture material.

The technical problem is solved by the method of obtaining pseudo-monofilament surgical suture material, which consists in vacuum impregnation with liquid photopolymerizable material, irradiation with UV radiation, washing, drying.

A method of obtaining a pseudo-monofilament surgical suture material is as follows.

To obtain a pseudo-monofilament surgical suture material, the thread is impregnated with liquid photopolymerizable material in vacuum at 30-60 ° C and a vacuum of 1 atm. The impregnated thread is passed through a calibration die and pulled through a UV irradiation unit with λ = 200-400 nm at a speed equal to the polymerization rate of the material. The obtained thread is washed in alcohol at 30-60 ° C for 2-8 hours and dried in a vacuum oven at 30-60 ° C with a vacuum of 1 atm for 2-8 hours. This method allows to obtain a non-toxic pseudomonofilament surgical suture material.

Claims (1)

A method of obtaining a pseudo-monofilament surgical suture material, comprising impregnating the thread with liquid polymerizable material, and drying it, characterized in that photopolymerizable material is used as the polymerizable material, by which the thread is vacuum impregnated at 30-60 ° C with a vacuum of 1 atm, the thread is pulled through the unit irradiation with UV radiation of 200-400 nm at a speed equal to the polymerization rate of the material, washed in alcohol at 30-60 ° C for 2-8 hours and dried in a vacuum oven at 30-60 ° C with a vacuum of 1 tm for 2-8 hours.