RU221537U1 - Autonomous mobile express laboratory for the safe analysis of pathogenic biological materials - Google Patents

Abstract

The utility model Autonomous Mobile Express Laboratory (AMEL) for the safe analysis of pathogenic biological materials refers to mobile complexes for the analysis of pathogenic biological materials, can be used in the field for sampling and testing them for the presence of dangerous and especially dangerous microorganisms that cause infectious diseases, in accordance with the requirements of SanPiN. An autonomous mobile express laboratory contains a group of equipment mounted on a rectangular platform of a vehicle to determine the required characteristics, including three sampling devices for safe collection of soil samples from given depths, installed in such a way that two sampling devices are located on the sides of the platform and one sampling device along in the middle of the rear side of the platform, so that the three sampling devices form an isosceles triangle with a base of 3 m and a height of 1.5 m, next to each sampling device on the platform there are gas cylinders connected to it by a hose, a block of vacuum pumps is placed on the platform, which connected by three coils to three portable gas analyzers included in the spectrometric laboratory unit, and by three gas outlets to each of the three sampling devices. Additionally, AMEL contains a power supply system, including a built-in electric generator. The useful model will be used to safely determine the presence of unknown burials (human or animal) with the ability to determine their contamination with dangerous bacteria (including anthrax).

Description

The utility model Autonomous Mobile Express Laboratory (AMEL) for the safe analysis of pathogenic biological materials refers to mobile complexes for the analysis of pathogenic biological materials, can be used in the field for sampling and testing them for the presence of dangerous and especially dangerous microorganisms that cause infectious diseases, in accordance with the requirements of SanPiN, and will be used for the safe determination of the presence of unknown burials (human or animal) with the possibility of determining their contamination with dangerous bacteria (including anthrax).

Currently, almost all developed countries produce and use, as part of mobile complexes for the analysis of pathogenic biological materials (agents), mobile biological laboratories designed for the indication and identification of pathogenic biological agents (PBA) and biological toxins [Parsons A., Matero P ., Adams M., Yeh K. Examining the utility and readiness of mobile and field transportable laboratories for biodefence and global health security-related purposes. Global Security: Health, Science and Policy. 2018; 3(1): 1-13. DOI: 10.1080/23779497.2018.1480403.]. These can be prefabricated modular (movable by any type of vehicle) and mobile (mounted on a vehicle chassis) complexes.

Foreign samples of specialized automotive laboratories are represented by universal automotive laboratories for RCB reconnaissance (radiation, chemical, biological) [Toader C, Epure G., Mosteanu D., Epure C, Iorga O., Florin I. Mobile deployable laboratory - chemical module. International conference Knowledge-based organization.2016: 22(30):677-80. DOI: 10.1515/kbo-2016-0116.], as well as specialized biological reconnaissance machines. Automotive laboratories are in service with special units of law enforcement ministries and departments and are designed to establish facts of the deliberate use of pathogenic biological agents [Cardozo M, Oliveira V.G.M., Sousa R.B., de Paula R.L. Chemical and biological mobile laboratory: infrastructure employed by Brazilian Army in emergency response actions. J. Phys.: Conf. Ser. 2018; 975:012003. DOI: 10.1088/1742-6596/975/1/012003].

Mobile biological laboratories of civil departments, designed for the indication and identification of pathogens of dangerous infectious diseases in the event of epidemics, have also become widespread at the present stage.

The most obvious example of the demand for mobile biological laboratories was their widespread use in 2014-2015 during the elimination of the Ebola virus disease (EVD) epidemic in West African countries, which did not have a network of their own stationary laboratories with the appropriate level of biological safety. [Popova A.Yu., Kutyrev V.V., editors. Elimination of the Ebola epidemic in the Republic of Guinea: experience of the specialized anti-epidemic team of Rospotrebnadzor. M.: LLC “Creative Information and Publishing Center”; 2016. 354 p.].

In addition, the processes of climate change - warming, causing changes in the boundaries of permafrost, for Rospotrebnadzor means problems of assessing the risk of the threat of permafrost thawing in the areas where cattle burial grounds, household and industrial waste dumps are located. This poses the task of justifying the requirements for adjusting social and hygienic monitoring programs with the inclusion of indicators characterizing the content of highly toxic pollutants and pathogens of dangerous infections and invasions transmitted along the food chain through traditional fishing objects of the population, as well as the social and climatic characteristics of the region. ["Russian Arctic" 6/2019. Prepared with the participation of scientists from the North-Western Scientific Center for Hygiene and Public Health, St. Petersburg].

One of the measures to increase the efficiency of epizootological monitoring in natural foci of infectious diseases of bacterial and viral nature may be the use of mobile laboratories that can be deployed on the territory of natural foci of infections, regardless of their landscape, geographic and climatic characteristics, and carry out comprehensive laboratory tests in the field analysis of samples of biological material and environmental objects collected during an epizootological survey, using modern research methods in compliance with biological safety requirements with the involvement of a minimum number of specialists.

In 2007-2008, for the first time in world practice, in RosNIPCI “Microbe” was scientifically substantiated, developed and, together with Avtospectr NN LLC (Nizhny Novgorod), a complex of mobile laboratories of a specialized anti-epidemic brigade (SPEB) was created on the basis of a KAMAZ 43118 chassis and special trailers . The scientific novelty of innovative developments is protected by six patents of the Russian Federation: patent No. 66723 “Mobile anti-epidemic complex”; patent No. 65434 “Laboratory of sanitary and hygienic research”; patent No. 65435 “Bacteriological laboratory”; patent No. 65436 “Indication laboratory”; patent No. 65437 “Laboratory of especially dangerous infections”; patent No. 65833 “Bacteriological research support unit.”

The complex included six modules: a headquarters module, indicator laboratories, especially dangerous infections, a bacteriological laboratory, a sanitary and hygienic laboratory and a bacteriological research support unit. The structural, functional and technical features of the laboratories of the mobile complex were discussed earlier [Onishchenko G.G., Kutyrev V.V., editors. Specialized anti-epidemic teams (SPEB): evolution of scientific concept and practical application. LLC "Bukva"; 2014. 572 p.].

Scientifically substantiated and created design documentation for a mobile indication laboratory for epizootological monitoring of especially dangerous and other natural focal infections.

The scientific novelty of this development is protected by patents of the Russian Federation (patent No. 112112 “Mobile laboratory for epizootological monitoring of particularly dangerous and other natural focal infections”; patent No. 98369 “Mobile laboratory for epizootological monitoring of particularly dangerous and other natural focal infections”).

The laboratories of the mobile complex ensure a high level of biological safety - BSL-2-3 in accordance with the criteria of the World Health Organization (WHO), which allowed them to be validated at the international level for the first time - WHO included them in the international response system in the fight against the Ebola epidemic .

The main areas of use of mobile biological laboratories in Russia are:

responding to emergency situations of a sanitary and epidemiological nature both in Russia and abroad;

strengthening territorial sanitary and anti-epidemic services during public events;

carrying out epizootological examination of natural foci of infectious diseases;

providing material and technical support to partner countries of the Russian Federation in the field of combating infectious diseases (Kutyrev V.V., Toporkov A.V., Karnaukhov I.G. The use of mobile laboratories for anti-epidemic provision of the population in emergency situations. Problems of especially dangerous infections. 2007;1:27-9).

However, the range of areas for using mobile biological laboratories to ensure the sanitary and epidemiological well-being of the population should expand.

A “Mobile complex laboratory” is known, containing a group of equipment mounted on a vehicle to determine the required characteristics, characterized in that it is equipped with a weather station for measuring ranges of wind speed, temperature and wind direction, a microprocessor gas analyzer that provides the necessary control of background concentrations of atmospheric air, working air zones, industrial emissions and technological processes, a noise-vibration measuring complex that provides acoustic measurements and monitoring of environmental noise, sampling devices that provide air sampling for dust and aerosols, and automatic sampling of gases, vapors and aerosols through an absorber, a carbon monoxide gas analyzer, providing measurement of the concentration of carbon monoxide in the atmosphere, a soil sampling device with a nozzle, a gas monitoring device for measuring the concentration of harmful substances in the air of a working area and industrial emissions and monitoring the contamination of soil, soil and water, a dosimeter-radiometer for monitoring the radiation situation, X-ray fluorescence a spectrometer to determine the content of toxic elements, a meter for the mass concentration of aerosol particles of various origins and chemical compositions, and a computer to ensure prompt registration of analysis results (RF utility model patent No. 50175, publ. December 27, 2005).

The well-known “Laboratory of Sanitary and Hygienic Research” is described in the RF utility model patent No. 65434, publ. 08/10/2007 The laboratory is mounted in a van body on the basis of a trailer for a KAMAZ vehicle and contains a hermetically sealed interior with a BSL-2 biological safety level, with a forced supply and exhaust ventilation system and life support equipment. The laboratory interior is divided by hermetically sealed partitions into a functional compartment intended for carrying out sanitary and hygienic studies, and a sanitary inspection room. Reception of biological material and its transfer to the research compartment is carried out through a hatch window built into the emergency exit door. The interior of the laboratory is equipped with the necessary equipment for sanitary and hygienic research. The laboratory is equipped with an audible alarm, a visual monitoring system for monitoring the operation of the filter-ventilation unit, and means of alerting about the operating mode.

The disadvantages of these devices are that they do not meet the requirements of regulatory documents on the safety of working with microorganisms of pathogenicity groups I-II.

The well-known “Laboratory of Particularly Dangerous Infections” is described in RF patent No. 65437, publ. 08/10/2007 The laboratory is mounted in a van body on the basis of a trailer for a KAMAZ vehicle and contains a hermetically sealed interior with a biological safety level of BSL-3, with a forced supply and exhaust ventilation system and life support equipment. The laboratory interior is divided by hermetically sealed partitions into functional compartments intended for bacteriological research and a sanitary inspection room. To receive biological material and transfer it to another compartment, transfer lock chambers are provided in the walls. The interior is equipped with all the necessary equipment for bacteriological research. The laboratory is equipped with an audible alarm system, an electrical visual system for monitoring the operation of the filter-ventilation unit, and means of alerting about the operating mode. The laboratory provides the ability to conduct bacteriological analysis of microorganisms of pathogenicity groups I-II.

The disadvantage of this model is that the final identification of isolated microorganisms using PCR, ELISA and other methods is carried out (by transferring them) in an indicator laboratory located outside the laboratory, which makes it possible to prepare the incoming biomaterial, but does not allow making a final conclusion about the presence of certain or other substances in the selected biomaterial. other pathogenic microorganisms. This leads to a loss of time, which can have unpredictable consequences in the conditions of a real focus of bacteriological infection.

The well-known “Mobile laboratory for epizootological monitoring of especially dangerous and other natural focal infections” (described in the patent for PM of the Russian Federation No. 112112, published on January 10, 2012). containing two equipped, functionally interconnected modules - indication and bacteriological, each of which has a hermetically sealed interior with a biological safety level of BSL-2; forced supply and exhaust ventilation system; divided by partitions into a sanitary inspection room and functional compartments; equipped with life support systems containing power supply, water supply, sewerage, heating, air conditioning and ventilation systems, a communication system, characterized in that each module is additionally equipped with an access control and management system integrated with an alarm system, while the access control and management system contains a central control and control device, power supply, electromechanical lock, personal card identifier unit and/or biometric fingerprint scanner unit, exit button, display devices, switching elements, communication lines, and the alarm system - power supply, emergency button, sound warning devices , switching elements, communication lines.

The disadvantage of the described devices is the location of monitoring and control devices for engineering systems directly in the laboratory compartments, which prevents technical personnel from accessing the laboratory premises during research and their maintenance requires stopping research work; The class II microbiological safety cabinet of type A2 installed in the laboratory is designed to work with microorganisms of III-IV pathogenicity groups and does not ensure compliance with biological safety requirements in accordance with regulatory documents regulating the rules for working with microorganisms of I-II pathogenicity groups. The most important thing is that these sanitary and hygienic research laboratories have a transfer window for transferring biological material into the compartment for receiving and working with infectious biological material, which, when opened, does not provide isolation of the infectious zone of the laboratory, which increases the risk of release of pathogenic biological agents (PBA) into environment.

A common drawback of all AMELs identified in the scientific and patent literature is the lack of safe extraction of soil samples, including those in permafrost, and the lack of safe sending it for further laboratory research under conditions characterizing the content of highly toxic pollutants and pathogens of dangerous infections and infestations transmitted by food chains through the objects of traditional fishing of the population, as well as the social and climatic characteristics of the region.

As a prototype, as the closest in its technical essence, utility model RF No. 50175, publ. 12/27/2005 “Mobile complex laboratory”.

The purpose of the utility model is to develop a more mobile, efficient and safe laboratory with broad functionality that allows for a safe operational complex of diagnostic studies of soils intended for stripping operations (construction, drilling operations, use for agricultural work, etc.) in accordance with the MUK 4.2.2413-08.

This problem is solved due to the fact that the autonomous mobile express laboratory (AMEL) contains a group of equipment mounted on a rectangular platform of the vehicle to determine the required characteristics, including three sampling devices for the safe collection of soil samples from given depths (RF patent PM No. 207417, publ.27.10.2021), installed so that two sampling devices are located on the sides of the platform and one sampling device in the middle of the rear side of the platform, so that the three sampling devices form an isosceles triangle with a base of 3 m and a height of 1.5 m , next to each sampling device on the platform there are gas cylinders connected to it by a hose; on the platform there is a block of vacuum pumps, which are connected by three coils to three portable gas analyzers included in the spectrometric laboratory unit, and three gas outlets to each of the three sampling devices.

AMEL also contains a power supply system, including a built-in electric generator.

These features are essential to form a stable set of essential features sufficient to obtain the required technical result.

The technical result of the claimed utility model is high safety for researchers in extracting a soil sample and studying gas from a burned soil sample, because the researcher has no contact with the gas sample throughout its passage through sealed channels. In addition, the great advantage of the claimed model is its high mobility and reduced labor intensity of sampling for research; versatility and efficiency due to the compactness of the claimed utility model when conducting surveys of large areas, due to the fact that the studies are carried out simultaneously from three soil sampling points, after combustion of which the gas is supplied simultaneously to three gas analyzers. Thus, the entire procedure takes less preparation time to measure and move to the next three points (at 4 m). This is especially effective when surveying large areas.

Localization and elimination of outbreaks of dangerous diseases requires immediate destruction of the source of infection, including by burning animal corpses [Journal of NBC Protection Corps. 2017. V. 1. No. 4 - pp. 50-58]. In “Veterinary and sanitary rules for the collection, disposal and destruction of biological waste” [Veterinary and sanitary rules for the collection, disposal and destruction of biological waste, approved. Chief State Veterinary Inspector of the Russian Federation on December 4, 1995 No. 13-7-2/469.], provides methods of disposal by burning animal corpses in trenches (various configurations of trenches are given with an indication of their dimensions) using firewood, rubber as combustible materials waste and other solid combustible materials, and also describes the possibilities for burning animal corpses in special ovens.

However, as practice shows, these measures do not guarantee complete safety in eliminating outbreaks of dangerous diseases.

During a survey by specialists of the Federal State Budgetary Institution “48 Central Research Institute” of the Russian Ministry of Defense of pestilence fields in the Yamal region of the Yamal-Nenets Autonomous Okrug (Yamalo-Nenets Autonomous Okrug) in 2017, 32 samples were taken from a soil depth of 15 cm for contamination with the anthrax pathogen. In two of them , No. 3 - ash residue from the site of burning a deer corpse, and No. 13 - biological material from a corpse that was not completely burned; specific DNA fragments of Bacillus anthracis were detected by real-time PCR. From these samples, pure cultures of the anthrax pathogen were obtained. [A.V. Savinykh, D.L. Pavlov, A.V. Kuznetsovsky et al. “Results of monitoring anthrax pestilence fields of the 2016 epizootic on the territory of the Yamal region of the Yamal-Nenets Autonomous Okrug,” Bulletin of the Russian Chemical Defense Defense Troops. 2017. Volume 1. No. 3. From 18-29].

This once again confirms the importance and relevance of the development of such useful models as the proposed autonomous mobile express laboratory (AMEL) device for the safe analysis of pathogenic biological materials. All work on the collection, transportation and preparation of samples from environmental objects is carried out in strict accordance with the requirements of SP 1.3.3118-13 “Safety of working with microorganisms of I-II pathogenicity (hazard) groups” [SP 1.3.3118-13. “Safety of working with microorganisms of I-II pathogenicity (hazard) groups.” Sanitary rules. M., 2014. 197 p.], as well as SP 1.2.036-95 “Procedure for recording, storage, transfer and transportation of microorganisms of pathogenicity groups I-IV” [SP 1.2.036-95. “The procedure for recording, storage, transfer and transportation of microorganisms of I-IV pathogenicity groups.” Sanitary rules. M., 1995. 81 p.].

The use of three sampling devices, which are devices for safe sampling of soil samples from given depths, including permafrost rocks according to RF patent No. 207417, published 10/27/2021, provides improved tactical and technical characteristics of AMEL, namely reducing the deployment time of the mobile complex due to the use modern technical means. Research is carried out simultaneously from three soil sampling points, after combustion of which the gas enters simultaneously into a spectrometric portable laboratory with three gas analyzers, which are connected to each of the three vacuum pumps by coils that reduce the temperature of the incoming gas. The presence of a block of three vacuum pumps that extract gases through gas outlets from sampling devices and supply them to the gas analyzer unit allows increasing the efficiency and safety of AMEL operation. At the same time, the requirements of MUK 4.2.2413-08 are met (Methodological instructions. 4.2. Control methods, biological and microbiological factors. Laboratory diagnostics and detection of the anthrax pathogen. Date of introduction 2008-09-01).

The rationality of AMEL and its safety, since the release of a dangerous fraction is prevented due to the high combustion temperature of the core, which allows the complex to be used for the safe selection and prompt study of soil samples in a wide range of environmental conditions - from extreme conditions of high-latitude regions to urban environment objects.

The versatility of AMEL is the ability to obtain samples not only for microbiological research, but also for analyzing the composition of materials, contaminants and other purposes. Thus, the risk of biological hazard is reduced by expanding the arsenal of engineering and technical means that ensure a high level of biological safety that meets international standards in the field of biological safety.

Timely detection of organic, bacteriological or toxic substances in the territory of proposed technical work, including in permafrost, that may pose a danger to people and the environment, will make it possible to substantiate the cessation of the design and construction of technical facilities in this territory.

The technical and economic efficiency of the proposed AMEL for assessing the territory during the design and construction of facilities, including in the permafrost zone, is due to the effective prevention of emergency situations of a technical and biological nature in the construction area, which makes it possible to prevent multimillion-dollar expenses for their elimination.

The inventive device is illustrated by a block diagram of an autonomous mobile express laboratory (AMEL) for the safe analysis of pathogenic biological materials.

Detailed description of the device and examples of its practical implementation

The autonomous mobile express laboratory contains a group of equipment mounted on a rectangular platform 1 of a vehicle (not indicated in the drawing) to determine the required characteristics: three devices for safe sampling of soil samples from given depths, including permafrost (according to RF patent No. 207417, publ. 27.10 .2021), hereinafter referred to as: sampling devices 2, each of which is connected to a gas cylinder 3, a telescopic crane 4, a block of three vacuum pumps 5, a spectrometric laboratory block of three portable gas analyzers 6 with three coils 7, gas outlets 8.

Sampling devices 2 (made according to RF patent No. 207417, published on October 27, 2021) - refer to devices for safe drilling of soil, including permafrost, and can be used for the safe selection of various soil samples in the field for laboratory research, both for for scientific purposes and for assessing lands for technological purposes. This device includes a cylindrical pipe with a pointed cutting edge and a device for extracting a sample, characterized in that the cylindrical drill pipe contains several through holes along the entire length on two opposite sides of the guide walls, the centers of which are located at a given distance from each other and coincide with the centers of the holes on the opposite guide wall, at the upper end of the drill pipe, a technological plug with a hole for the drive is installed, and a cutter is located at the lower end; the device for safe sample extraction is made in the form of a thermoblock containing a casing pipe with two holes, the dimensions and shape of which coincide with the hole on the drill pipe, while a burner is rigidly located to the hole on one side of the casing pipe, and on the other side of the casing pipe a collector fits to the hole ash residue, and the drill pipe is inserted into the casing pipe. The holes on the drill pipe are made in the shape of a rectangle, and the distances between their centers correspond to the step of taking a soil sample. The length of the casing pipe is chosen equal to the length of the drill pipe section containing one hole on its guides, the dimensions and shape of which coincide with the hole on the drill pipe. The cutter contains a cutting edge and a stopper located around the circumference.

An experimental model of this device for safely taking soil samples from given depths, including permafrost, was tested by us in the field and showed full applicability and performance. This provided an opportunity to include it in the development of AMEL for the safe analysis of pathogenic biological materials.

An autonomous mobile express laboratory for the safe analysis of pathogenic biological materials is mounted on a mobile platform 1 on the basis of a trailer for a KAMAZ off-road vehicle, tractor or all-terrain vehicle and contains three sampling devices 2 according to the scheme: two sampling devices on the sides of platform 1 and one sampling device device in the middle of the rear side of platform 1, so that the three sampling devices 2 form an isosceles triangle with a base of 3 m and a height of 1.5 m. Next to each sampling device 2 on platform 1, a gas cylinder 3 is attached, connected by a hose to the sampling device 2 Also, on platform 1 there is a block of vacuum pumps 5 connected to three portable gas analyzers 6 included in the spectrometric laboratory block with three coils 7 for removing gas (from burnt samples) entering through coils 8 from each of the three sampling devices 2. On the platform 1, a telescopic crane 4 is also installed for moving sampling devices 2 from platform 1 to the research site and returning to platform 1 (the power supply system is not shown).

To conduct research at a given point in the area, sampling devices 2 with a telescopic crane 4 are lowered one by one from the platform 1 and installed to collect soil in accordance with the operating instructions for this device on three sides of the platform 1, so that the three sampling devices 2 form an isosceles triangle with base 4 m and height 2 m when installed on the research site, thus, the rule of sampling in a certain configuration in the form of an “envelope” with a side of 4 m is observed (in accordance with the requirements of MUK 4.2.2413-08). Using sampling devices 2, drilling is carried out to a depth of 2 m, followed by slow extraction of the soil sample in accordance with the instructions for the operation of sampling devices 2. Since AMEL has a spectrometric laboratory unit with portable gas analyzers, the gas from the combustion of the soil sample through gas outlets 8 is sucked out of the sampling devices 2 vacuum pumps 5 and from them through coils 7 it goes to gas analyzers 6.

When moving through the study area, platform 1 with the equipment installed on it moves to a distance of 4 m from the place where the first sample is taken, in order to comply with the requirements specified in the MUK about taking samples according to a certain configuration in the form of an “envelope” with a side of 4 m, after which a new collection of soil samples is repeated. During the study, soil samples obtained by sampling devices 2 are burned directly in them and the gas from the burned soil sample is sucked out of the sampling devices 2 by vacuum pumps 5 through gas outlets 8 and from them through coils 7 is supplied to gas analyzers 6 in the spectrometric laboratory block.

Such movements are carried out throughout the entire study area. All results obtained are recorded in a spectrometric laboratory, where the necessary measurements of the content of traces of burnt bacteria or Ca or its compounds in the gas are made. Thus, it can be stated that the burial of a person or animal has been discovered. If traces of burnt bacteria are detected, we can make an assumption that the soil is contaminated and take all necessary measures to ensure the safety of the area being examined.

Determining the elemental composition of the gas released during the production of ash residue makes it possible to identify not only the presence of cattle burial grounds, but also the content of highly toxic and bacteriological pollutants. In this case, the site for taking a soil sample is clogged with a liquid fraction (for example, concrete). Install a warning sign and report the coordinates of the detected outbreak to the relevant sanitary and epidemiological control authorities.

The AMEL we declare is ergonomic and does not require a large number of maintenance and technical personnel. It can be used both as part of a mobile anti-epidemic complex when eliminating the epidemiological consequences of natural disasters, man-made disasters, emergency biological and social situations and the commission of bioterrorist acts, and separately, depending on the assigned tasks.

This utility model is illustrated by a specific example, which, however, is not the only possible one, but clearly demonstrates the possibility of achieving the required technical result by the given set of features.

The AMEL experimental complex was tested by us in the field with the study of 3 soil samples obtained at various specified depths. At a depth of 20 cm, 1st sample: soil 1, composition close to tundra; at a depth of 40 cm, 2nd sample: soil 1 with the addition of 5% chalk as a calcium simulator and at a depth of 60 cm, 3rd sample: soil 1 with the addition of 5% bone remains of SGS). The gas obtained during the production of ash residues from these samples was studied using a gas analyzer in laboratory conditions. As a result, data were obtained on the presence of Ca5(PO4)3(OH) in sample 3, which was an order of magnitude different from samples 1 and 2, which was a reliable indication of the presence of bone remains in the soil sample (a sign of a cattle burial ground).

Thus, the declared utility model in experimental execution showed full applicability and performance.

The claimed utility model AMEL allows researchers to safely obtain gas from burned samples without removing the samples themselves to the surface, and to examine it using gas analytical methods for the content of traces of organic, bacteriological or toxic substances, including relict microbiota of permafrost in the area of technical work or their absence. This allows you to quickly make a decision on stripping or disinfecting the area and reduce physical costs, simplify and reduce the cost of the entire process. The big advantage of AMEL over well-known analogues is its compact dimensions and weight; simplicity and ease of operation, achieved due to the fact that no additional modules are required, divided by hermetically sealed partitions into functional compartments intended for bacteriological research, sanitary inspection rooms, transfer lock chambers for receiving biological material and transferring it to other compartments.

Claims (1)

Autonomous mobile express laboratory for the safe analysis of pathogenic biological materials, containing a group of equipment mounted on a vehicle to determine the required characteristics, including a soil sampling device and a gas analyzer, characterized in that the group of equipment to determine the required characteristics is mounted on a rectangular platform of the vehicle means and contains three sampling devices installed in such a way that two sampling devices are located on the sides of the platform and one sampling device is located in the middle of the rear side of the platform, so that the three sampling devices form an isosceles triangle with a base of 3 m and a height of 1.5 m, next to each sampling device on the platform there are gas cylinders connected to it by a hose; on the platform there is a block of vacuum pumps, which are connected by three coils to three portable gas analyzers included in the spectrometric laboratory unit, and three gas outlets to each of the three sampling devices.

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