RU2192867C2 - Method for treating the cases of peptic gastric and duodenal ulcer disease - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: method involves administering traditional medicamentous treatment in combination with mineral-containing preparation administered per os. Tripolite taken from deposits in Chuvash republic and Kurgan region and administered as aqueous suspension containing 4-6 g of tripolite in 150-200 ml of water. EFFECT: accelerated treatment method.

Description

 The invention relates to medicine, namely to gastroenterology, and can be used in the treatment of peptic ulcer of the stomach and duodenum.

 A known method of treating gastric ulcer and duodenal ulcer, including co-administration, along with treatment according to indications of pharmaceuticals or medicinal herbs, a biologically active naturally balanced mixture of vitally important, at least eighteen amino acids in combination with micro and macro elements. Patent 2091067, CL A 61 K 31/195, A 61 K 33/00, 6 A 61 K 31/195, 1997

 There is a method of treating gastric ulcer and duodenal ulcer using esophagogastroduodenoscopy, during which an emulsion of Eikonol edible oil is applied to a ulcer defect and surrounding ulcer in a dose of 5-7 ml once every 2-3 days with a treatment course of 10-18 days.

 The disadvantages of this method include the use of esophagogastroduodenoscopy, which complicates the process and creates a side pain effect when introducing a healing drug into the patient's body.

 The closest way to treat peptic ulcer of the stomach and duodenum is the method of ingesting a dietary supplement of complex action Litovit, consisting of natural minerals such as zeolite, wheat and rye bran. Litovit is taken 40-60 minutes before meals or 1.5-2 hours after eating, and with the simultaneous use of medications, Litovit and medications are taken with a difference of 1.5-2 hours.

 The disadvantages of this method include the content in Lithuania of bran, which is fiber and which can cause mechanical injury to peptic ulcer during exacerbation of gastric ulcer. In this case, the well-known supplement is started to be taken gradually increasing the dose and taken for a sufficiently long time (35 days). Bagatov V.I. et al. Litovit / AOZT NPF Nov. Novosibirsk, 1997, p. 2, 29, 34.

 The invention solves the problem of creating a method that expands the arsenal of technical equipment for this purpose, which allows to reduce the treatment time for peptic ulcer of the stomach and duodenum.

 This is achieved by the fact that a method of treating gastric ulcer and duodenal ulcer by administering traditional medications together with oral therapy with a mineral-containing preparation, as a mineral-containing preparation, tripoli is used in the Pervomaisky deposit of the Alatyr region of the Chuvash Republic or the Shadrinsky deposit of the Kurgan region in the form of an aqueous suspension of 4, consisting of 4 -6 g tripoli in 150-200 ml of water.

 To prepare the suspension, Tripoli was used in the Pervomaisky deposit in the Alatyr district of the Chuvash Republic, containing,%: silicon oxides 60.3-72.5; iron 2.8-4.2; aluminum 8.4-10.1; calcium 2.6-12.3; magnesium 0.9-1.3; sodium 0.18-0.29; potassium 1.4-1.5, or tripoli of the Shadrinsk deposit of the Kurgan region, containing,%: silicon oxides 57.3-68.9; iron 4.4-8.4; aluminum 11.2-20.8; calcium 0.1-2.3; magnesium 1.6-3.0.

 From trace elements in tripoli contain: copper, molybdenum, fluorine, manganese, phosphorus. Heavy metals (arsenic, cadmium, mercury) are not contained.

 Finely ground tripoli with a particle size of 0.03-0.04 mm was used to prepare an aqueous suspension.

 The difference between the claimed solutions and the known ones is the use of tripoli as a mineral-containing preparation in the form of an aqueous suspension consisting of 4-6 g of tripoli in 150-200 ml of water. The advantage of using an aqueous tripoli suspension is that it has a mild effect on the ulcer surface, does not cause mechanical injury to the ulcer during an exacerbation of the ulcer, and significantly reduces the time of ulcer scarring and the treatment time.

 A method of treating gastric ulcer and duodenal ulcer is illustrated by the following examples.

 Example 1. Patient S., born in 1956, was treated with a diagnosis of acute peptic ulcer of the duodenum in the acute stage, an ulcer with a diameter of 0.7 cm is located in the bulb on the front wall. The patient was prescribed a course of treatment using antacids, antispasmodics, anticholinergics, sedatives. 1 hour before breakfast and 2 hours after dinner, the patient received 1 teaspoon of lithovite for 5 days. Then, over the next 5 days, the patient received 1 teaspoon of lithovite 3 times a day 1 hour before meals. Over the next 5 days, the patient received 1 dessert spoon 2 times a day after meals. After a break of 5 days, the patient received 1 dessert spoon 2 times a day for 15 days. A control endoscopic examination after treatment revealed complete scarring of the ulcer and a significant decrease in superficial gastric changes.

 Example 2. Patient M., born in 1940, was treated with a diagnosis of acute peptic ulcer of the duodenum in the acute stage, an ulcer with a diameter of 0.8 cm is located in the bulb on the front wall. The patient was prescribed a course of complex therapy with the use of antacids, antispasmodics, anticholinergics, sedatives. 0.5 hours before breakfast and 2 hours after dinner, the patient received an aqueous suspension consisting of 4 g tripoli and 150 ml of water. A control endoscopic examination on day 18 revealed a complete scarring of the ulcer and a significant decrease in superficial gastric changes. The patient was discharged on day 18 in satisfactory condition. During follow-up examinations of the patient 2 months after discharge from the hospital, a persistent tender scar was observed at the site of the ulcer. There were no seasonal exacerbations.

 Example 3. Patient A., born in 1949, was treated with a diagnosis of peptic ulcer, duodenal ulcer with a diameter of 0.9 cm. The patient was prescribed the usual complex therapy 1 hour before breakfast and after 2.5 hours after dinner, the patient received an aqueous suspension consisting of 5 g tripoli and 150 ml of water. During the control endoscopic examination on day 20, ulcer scarring and the disappearance of superficial inflammatory changes in the mucosa were noted. The patient was discharged from the hospital in satisfactory condition.

 Example 4. Patient P., born in 1964, was treated with a diagnosis of peptic ulcer, duodenal ulcer with a diameter of 0.7 cm. The patient was prescribed the usual complex drug therapy 1 hour before breakfast and 1.5 hours before dinner, the patient received an aqueous suspension consisting of 6 g tripoli and 200 ml of water. A control endoscopic examination on day 18 revealed a decrease in peptic ulcer and the disappearance of superficial inflammatory changes in the mucosa. The patient was discharged from the hospital in satisfactory condition.

 Example 5. Patient N., born in 1947, suffers from a stomach ulcer for 10 years. While in hospital treatment, the patient received ranitidine and 2 times a day, morning and evening, 0.5 hours before meals, an aqueous tripoli suspension consisting of 6 g tripoli per 200 ml of water. After a 20-day course, a stable remission began, the general condition of the patient improved, he began to gain weight. There are no signs indicating the advisability of repeating the course.

 Thus, the use of an aqueous suspension of tripoli in peptic ulcer of the duodenum leads to a decrease in the size of the ulcer, accelerating its scarring and shortening the treatment time.

Claims (1)

 A method of treating gastric ulcer and duodenal ulcer by administering traditional medications together with oral therapy with a mineral-containing preparation, characterized in that tripoli of the Pervomaisky deposit in the Alatyr region of the Chuvash Republic or the Shadrinsk deposit of the Kurgan region in the form of an aqueous suspension consisting of 4 is used as a mineral-containing preparation 6 g tripoli per 150-200 ml of water.