RU2026290C1 - 3r,5s-(+)-7-[4-(4-фторфенил)-2,6- диизопропил-5-метоксиметил-пирид-3-ил]-3,5- диоксигептеновая кислота в эритро-(e)-конфигурации в виде физиологически переносимой соли металла в качестве ингибитора биосинтеза холестерина - Google Patents

3r,5s-(+)-7-[4-(4-фторфенил)-2,6- диизопропил-5-метоксиметил-пирид-3-ил]-3,5- диоксигептеновая кислота в эритро-(e)-конфигурации в виде физиологически переносимой соли металла в качестве ингибитора биосинтеза холестерина Download PDF

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Publication number
RU2026290C1
RU2026290C1 SU915010264A SU5010264A RU2026290C1 RU 2026290 C1 RU2026290 C1 RU 2026290C1 SU 915010264 A SU915010264 A SU 915010264A SU 5010264 A SU5010264 A SU 5010264A RU 2026290 C1 RU2026290 C1 RU 2026290C1
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RU
Russia
Prior art keywords
pyrid
methoxymethyl
fluorophenyl
diisopropyl
acid
Prior art date
Application number
SU915010264A
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English (en)
Russian (ru)
Inventor
Ангербауер Рольф
De]
Фай Петер
Хюбш Вальтер
Филиппс Томас
Бишофф Хильмар
Петцинна Дитер
Шмидт Дельф
Томас Гюнтер
Original Assignee
Байер Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Байер Аг filed Critical Байер Аг
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Publication of RU2026290C1 publication Critical patent/RU2026290C1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
SU915010264A 1990-12-14 1991-12-13 3r,5s-(+)-7-[4-(4-фторфенил)-2,6- диизопропил-5-метоксиметил-пирид-3-ил]-3,5- диоксигептеновая кислота в эритро-(e)-конфигурации в виде физиологически переносимой соли металла в качестве ингибитора биосинтеза холестерина RU2026290C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4040026A DE4040026A1 (de) 1990-12-14 1990-12-14 Substituierte pyridyl-dihydroxy-heptensaeure und deren salze
DEP4040026.3 1990-12-14

Publications (1)

Publication Number Publication Date
RU2026290C1 true RU2026290C1 (ru) 1995-01-09

Family

ID=6420376

Family Applications (1)

Application Number Title Priority Date Filing Date
SU915010264A RU2026290C1 (ru) 1990-12-14 1991-12-13 3r,5s-(+)-7-[4-(4-фторфенил)-2,6- диизопропил-5-метоксиметил-пирид-3-ил]-3,5- диоксигептеновая кислота в эритро-(e)-конфигурации в виде физиологически переносимой соли металла в качестве ингибитора биосинтеза холестерина

Country Status (4)

Country Link
DE (1) DE4040026A1 (xx)
RU (1) RU2026290C1 (xx)
UA (1) UA26428A (xx)
ZA (1) ZA919833B (xx)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ЕР 325130 А2, кл. C 07D213/65, 1989. *

Also Published As

Publication number Publication date
UA26428A (uk) 1999-08-30
DE4040026A1 (de) 1992-06-17
ZA919833B (en) 1992-09-30

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20031214