RU2020115256A3 - - Google Patents

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Publication number
RU2020115256A3
RU2020115256A3 RU2020115256A RU2020115256A RU2020115256A3 RU 2020115256 A3 RU2020115256 A3 RU 2020115256A3 RU 2020115256 A RU2020115256 A RU 2020115256A RU 2020115256 A RU2020115256 A RU 2020115256A RU 2020115256 A3 RU2020115256 A3 RU 2020115256A3
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RU
Russia
Application number
RU2020115256A
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RU2020115256A (ru
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Publication of RU2020115256A publication Critical patent/RU2020115256A/ru
Publication of RU2020115256A3 publication Critical patent/RU2020115256A3/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0681Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2020115256A 2017-10-02 2018-09-26 Способы предотвращения восстановления дисульфидной связи в сборе клеточной культуры RU2020115256A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762566746P 2017-10-02 2017-10-02
US62/566,746 2017-10-02
PCT/US2018/052800 WO2019070469A1 (en) 2017-10-02 2018-09-26 METHODS FOR PREVENTING DISULFIDE LINK REDUCTION IN A CELL CULTURE HARVEST

Publications (2)

Publication Number Publication Date
RU2020115256A RU2020115256A (ru) 2021-11-08
RU2020115256A3 true RU2020115256A3 (ru) 2022-02-16

Family

ID=63896645

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2020115256A RU2020115256A (ru) 2017-10-02 2018-09-26 Способы предотвращения восстановления дисульфидной связи в сборе клеточной культуры

Country Status (15)

Country Link
US (1) US20200237911A1 (ru)
EP (2) EP4074340A1 (ru)
JP (1) JP2020535825A (ru)
KR (1) KR20200058425A (ru)
CN (1) CN111182922A (ru)
AU (1) AU2018345511A1 (ru)
BR (1) BR112020006487A2 (ru)
CA (1) CA3077752A1 (ru)
IL (1) IL273593A (ru)
MX (1) MX2020003011A (ru)
PE (1) PE20201147A1 (ru)
RU (1) RU2020115256A (ru)
SG (1) SG11202002009PA (ru)
TW (1) TW201927335A (ru)
WO (1) WO2019070469A1 (ru)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ540895A (en) * 2003-01-09 2007-03-30 Genentech Inc Purification of polypeptides with ethacridine lactate
US20090053786A1 (en) * 2007-07-09 2009-02-26 Yung-Hsiang Kao Prevention of disulfide bond reduction during recombinant production of polypeptides
WO2017196810A1 (en) * 2016-05-10 2017-11-16 Medimmune, Llc Prevention of protein disulfide bond reduction
AU2018218548A1 (en) * 2017-02-08 2019-07-25 Pfizer Inc. Large scale production process for capped and un-capped antibody cysteines and their use in therapeutic protein conjugation

Also Published As

Publication number Publication date
EP3691683A1 (en) 2020-08-12
EP3691683B1 (en) 2022-03-16
KR20200058425A (ko) 2020-05-27
SG11202002009PA (en) 2020-04-29
US20200237911A1 (en) 2020-07-30
WO2019070469A1 (en) 2019-04-11
CN111182922A (zh) 2020-05-19
PE20201147A1 (es) 2020-10-26
JP2020535825A (ja) 2020-12-10
MX2020003011A (es) 2020-07-22
RU2020115256A (ru) 2021-11-08
IL273593A (en) 2020-05-31
CA3077752A1 (en) 2019-04-11
AU2018345511A1 (en) 2020-03-26
EP4074340A1 (en) 2022-10-19
BR112020006487A2 (pt) 2020-10-13
TW201927335A (zh) 2019-07-16

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