RU2019115337A3 - - Google Patents
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- Publication number
- RU2019115337A3 RU2019115337A3 RU2019115337A RU2019115337A RU2019115337A3 RU 2019115337 A3 RU2019115337 A3 RU 2019115337A3 RU 2019115337 A RU2019115337 A RU 2019115337A RU 2019115337 A RU2019115337 A RU 2019115337A RU 2019115337 A3 RU2019115337 A3 RU 2019115337A3
- Authority
- RU
- Russia
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/26—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing carboxyl groups by reaction with HCN, or a salt thereof, and amines, or from aminonitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/12—Acetic acid esters
- C07C69/14—Acetic acid esters of monohydroxylic compounds
- C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
- C07C69/157—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16206723.5 | 2016-12-23 | ||
| EP16206723 | 2016-12-23 | ||
| PCT/EP2017/084369 WO2018115434A1 (en) | 2016-12-23 | 2017-12-22 | Improved synthesis of lysine acetylsalicylate · glycine particles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2019115337A RU2019115337A (ru) | 2021-02-01 |
| RU2019115337A3 true RU2019115337A3 (cg-RX-API-DMAC10.html) | 2021-03-12 |
| RU2764573C2 RU2764573C2 (ru) | 2022-01-18 |
Family
ID=57680128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019115337A RU2764573C2 (ru) | 2016-12-23 | 2017-12-22 | Улучшенный синтез частиц ацетилсалицилата лизина ⋅ глицина |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10882811B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3558920B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP7012725B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN110114333B (cg-RX-API-DMAC10.html) |
| AU (1) | AU2017383071B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3044137C (cg-RX-API-DMAC10.html) |
| DK (1) | DK3558920T3 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2877856T3 (cg-RX-API-DMAC10.html) |
| PT (1) | PT3558920T (cg-RX-API-DMAC10.html) |
| RU (1) | RU2764573C2 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2018115434A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113105326A (zh) * | 2021-03-24 | 2021-07-13 | 海南卓华制药有限公司 | 赖氨匹林的制备方法及应用 |
| AU2023205426A1 (en) | 2022-01-05 | 2024-06-13 | Aspiair Gmbh | Improved synthesis of lysine acetylsalicylate · glycine particles |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2101867A (en) | 1934-08-18 | 1937-12-14 | Clemmy O Miller | Manufacture of water-soluble, storage-stable acetylsalicylic acid products |
| FR1295304A (fr) | 1956-05-07 | 1962-06-08 | Equilibre Biolog L | Nouveau sel de l'acide acétyl-salicylique et son procédé de préparation |
| US3392195A (en) | 1963-09-09 | 1968-07-09 | Galat Alexander | Amino acid derivatives |
| ES385222A1 (es) | 1970-11-05 | 1973-04-01 | Liade Sa Lab | Procedimiento de obtencion de una sal soluble del acido a- cetil salicilico. |
| JPS5610110A (en) | 1979-07-06 | 1981-02-02 | Green Cross Corp:The | Acetyl salicylate salt preparation for injection |
| US4446132A (en) | 1982-03-11 | 1984-05-01 | Dynatech Laboratories Incorporated | Nontoxic aspirin composition |
| FR2611501B1 (fr) | 1987-03-04 | 1991-12-06 | Corbiere Jerome | Nouvelles compositions pharmaceutiques pour la voie buccale a base d'acetylsalielylate de lysine et leur procede d'obtention |
| CN1043138C (zh) * | 1992-05-22 | 1999-04-28 | 安徽省蚌埠安宝药厂 | 赖氨匹林的制造方法 |
| DE10034802A1 (de) | 2000-07-18 | 2002-01-31 | Bayer Ag | Stabile Salze von O-Acetylsalicylsäure mit basischen Aminosäuren |
| DE10202019A1 (de) * | 2002-01-18 | 2003-07-24 | Bayer Ag | Stabile Salze von o-Acetylsalicylsäure mit basischen Aminosäuren II |
| US20060166901A1 (en) * | 2005-01-03 | 2006-07-27 | Yu Ruey J | Compositions comprising O-acetylsalicyl derivatives of aminocarbohydrates and amino acids |
| DE102005025283A1 (de) * | 2005-06-02 | 2006-12-07 | Bayer Healthcare Ag | Stabiler Wirkstoffkomplex von Salzen der o-Acetylsalicylsäure mit basischen Aminosäuren und Glycin |
| DE102005049293A1 (de) | 2005-10-15 | 2007-04-26 | Bayer Healthcare Ag | Kombinationspräparate von Salzen oder o-Acetylsalicylsäure |
| DE102008004386A1 (de) * | 2008-01-14 | 2009-07-23 | Activaero Gmbh | Verwendung eines Acetylsalicylsäuresalzes zur Behandlung viraler Infektionen |
| FR2965261B1 (fr) * | 2009-09-30 | 2012-10-26 | Holis Technologies | Procede de preparation d'un sel d'acide o-acetylsalicylique d'un acide amine basique et composition obtenue par ce procede |
| FR2973370B1 (fr) | 2011-03-29 | 2013-05-03 | Holis Technologies | Procede a faible cout pour la preparation d'un acide o-acetylsalicyclique et d'un acide amine basique |
| CN102503845A (zh) * | 2011-09-28 | 2012-06-20 | 广州普星药业有限公司 | 一种dl-赖氨酸阿司匹林盐的制备方法及其应用 |
| ITMI20121144A1 (it) | 2012-06-28 | 2013-12-29 | Dipharma Francis Srl | Procedimento per la preparazione di un sale di un farmaco antinfiammatorio non steroideo |
| FR3021654B1 (fr) | 2014-05-28 | 2016-06-24 | Unither Pharmaceuticals | Procede de preparation d'un sel d'acide acetylsalicylique et d'un acide amine basique |
| EP3393517B1 (en) * | 2015-12-22 | 2021-08-11 | AspiAir GmbH | Acetylsalicylic acid for use in the treatment of moderate to severe influenza |
-
2017
- 2017-12-22 CA CA3044137A patent/CA3044137C/en active Active
- 2017-12-22 JP JP2019533172A patent/JP7012725B2/ja active Active
- 2017-12-22 WO PCT/EP2017/084369 patent/WO2018115434A1/en not_active Ceased
- 2017-12-22 RU RU2019115337A patent/RU2764573C2/ru active
- 2017-12-22 AU AU2017383071A patent/AU2017383071B2/en active Active
- 2017-12-22 CN CN201780080190.4A patent/CN110114333B/zh active Active
- 2017-12-22 EP EP17822689.0A patent/EP3558920B1/en active Active
- 2017-12-22 PT PT178226890T patent/PT3558920T/pt unknown
- 2017-12-22 US US16/472,726 patent/US10882811B2/en active Active
- 2017-12-22 DK DK17822689.0T patent/DK3558920T3/da active
- 2017-12-22 ES ES17822689T patent/ES2877856T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018115434A1 (en) | 2018-06-28 |
| CA3044137C (en) | 2021-06-15 |
| PT3558920T (pt) | 2021-06-09 |
| DK3558920T3 (da) | 2021-07-05 |
| ES2877856T3 (es) | 2021-11-17 |
| EP3558920A1 (en) | 2019-10-30 |
| AU2017383071A1 (en) | 2019-06-06 |
| US20190322610A1 (en) | 2019-10-24 |
| US10882811B2 (en) | 2021-01-05 |
| EP3558920B1 (en) | 2021-04-07 |
| RU2764573C2 (ru) | 2022-01-18 |
| JP7012725B2 (ja) | 2022-01-28 |
| CN110114333A (zh) | 2019-08-09 |
| CA3044137A1 (en) | 2018-06-28 |
| RU2019115337A (ru) | 2021-02-01 |
| JP2020514261A (ja) | 2020-05-21 |
| CN110114333B (zh) | 2022-12-02 |
| AU2017383071B2 (en) | 2021-04-29 |
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