RU2017123275A - COMBINATION OF CHONDROPROTECTIVE AGENT WITH NSAID - Google Patents

COMBINATION OF CHONDROPROTECTIVE AGENT WITH NSAID Download PDF

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Publication number
RU2017123275A
RU2017123275A RU2017123275A RU2017123275A RU2017123275A RU 2017123275 A RU2017123275 A RU 2017123275A RU 2017123275 A RU2017123275 A RU 2017123275A RU 2017123275 A RU2017123275 A RU 2017123275A RU 2017123275 A RU2017123275 A RU 2017123275A
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RU
Russia
Prior art keywords
tool according
auxiliary substances
comprises auxiliary
periodontopathy
chondroitin
Prior art date
Application number
RU2017123275A
Other languages
Russian (ru)
Other versions
RU2017123275A3 (en
RU2742172C2 (en
Inventor
Алексей Валерьевич Чекалов
Original Assignee
Общество с ограниченной ответственностью "ФБК"
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Application filed by Общество с ограниченной ответственностью "ФБК" filed Critical Общество с ограниченной ответственностью "ФБК"
Priority to RU2017123275A priority Critical patent/RU2742172C2/en
Priority to PCT/RU2018/000345 priority patent/WO2019004868A2/en
Publication of RU2017123275A publication Critical patent/RU2017123275A/en
Publication of RU2017123275A3 publication Critical patent/RU2017123275A3/ru
Application granted granted Critical
Publication of RU2742172C2 publication Critical patent/RU2742172C2/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (15)

1. Средство для перорального применения в лечении остеоартроза периферических суставов, межпозвонкового остеохондроза, остеоартроза и остеопороза, пародонтопатии и/или для ускорения формирования костной мозоли при переломах, содержащее диацереин, хондроитин и глюкозамин.1. An agent for oral use in the treatment of peripheral joint osteoarthrosis, intervertebral osteochondrosis, osteoarthritis and osteoporosis, periodontopathy and / or to accelerate the formation of bone marrow in fractures containing diacerein, chondroitin and glucosamine. 2. Средство по п. 1, отличающееся тем, что представляет собой капсулу.2. The tool according to p. 1, characterized in that it is a capsule. 3. Средство по п. 1, отличающееся тем, что представляет собой саше.3. The tool according to p. 1, characterized in that it is a sachet. 4. Средство по п. 1, отличающееся тем, что представляет собой таблетку.4. The tool according to p. 1, characterized in that it is a tablet. 5. Средство по 2, отличающееся тем, что дополнительно содержит вспомогательные вещества.5. The tool according to 2, characterized in that it further comprises auxiliary substances. 6. Средство по 5, отличающееся тем, что вспомогательные вещества представляют собой кислоту стеариновую, магния стеарат и/или марганца сульфат.6. The tool according to 5, characterized in that the auxiliary substances are stearic acid, magnesium stearate and / or manganese sulfate. 7. Средство по 3, отличающееся тем, что дополнительно содержит вспомогательные вещества.7. The tool according to 3, characterized in that it further comprises auxiliary substances. 8. Средство по 7, отличающееся тем, что вспомогательные вещества представляют собой натрия хлорид, аспартам, сорбитол, лимонная кислота и/или карбовакс 4000.8. The tool according to 7, characterized in that the excipients are sodium chloride, aspartame, sorbitol, citric acid and / or carbovax 4000. 9. Средство по 4, отличающееся тем, что дополнительно содержит вспомогательные вещества.9. The tool according to 4, characterized in that it further comprises auxiliary substances. 10. Средство по 9, отличающееся тем, что вспомогательные вещества представляют собой кальция фосфат двузамещенный, микрокристаллическую целлюлозу, магния стеарат, стеариновую кислоту, натрия кроскармеллозу, гидроксипропилметилцеллюлозу, титана двуокись (Е171) и/или триацетин.10. The tool according to 9, characterized in that the excipients are calcium phosphate disubstituted, microcrystalline cellulose, magnesium stearate, stearic acid, sodium croscarmellose, hydroxypropyl methyl cellulose, titanium dioxide (E171) and / or triacetin. 11. Средство по п. 1, отличающееся тем, что содержит:11. The tool according to p. 1, characterized in that it contains: Диацереин от около 10 до около 200 мг;Diacerein from about 10 to about 200 mg; Хондроитин от около 200 до около 1000 мг;Chondroitin from about 200 to about 1000 mg; Глюкозамин от около 200 до около 1000 мг.Glucosamine from about 200 to about 1000 mg. 12. Применение средства по любому из пп. 1-11 для лечения остеоартроза периферических суставов, межпозвонкового остеохондроза, остеоартроза и остеопороза, пародонтопатии и/или для ускорения формирования костной мозоли при переломах.12. The use of funds according to any one of paragraphs. 1-11 for the treatment of peripheral joint osteoarthritis, intervertebral osteochondrosis, osteoarthrosis and osteoporosis, periodontopathy and / or to accelerate the formation of bone marrow in fractures.
RU2017123275A 2017-06-30 2017-06-30 Combination of a chondroprotective agent with an nsaid RU2742172C2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
RU2017123275A RU2742172C2 (en) 2017-06-30 2017-06-30 Combination of a chondroprotective agent with an nsaid
PCT/RU2018/000345 WO2019004868A2 (en) 2017-06-30 2018-06-28 Combination of a chondroprotective agent with an nsaid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2017123275A RU2742172C2 (en) 2017-06-30 2017-06-30 Combination of a chondroprotective agent with an nsaid

Publications (3)

Publication Number Publication Date
RU2017123275A true RU2017123275A (en) 2019-01-09
RU2017123275A3 RU2017123275A3 (en) 2019-01-09
RU2742172C2 RU2742172C2 (en) 2021-02-02

Family

ID=64184153

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017123275A RU2742172C2 (en) 2017-06-30 2017-06-30 Combination of a chondroprotective agent with an nsaid

Country Status (2)

Country Link
RU (1) RU2742172C2 (en)
WO (1) WO2019004868A2 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1314361C (en) * 2003-04-02 2007-05-09 李安虎 Joint healthy beverage or food and preparation thereof
MX2007011931A (en) * 2007-09-26 2009-03-26 World Trade Imp Export Wtie Ag Pharmaceutical composition combining an antiarthritic agent and an interleukin-1 inhibiting agent, which can be used to control and treat osteoarthritis and related diseases.
EA019542B1 (en) * 2007-11-23 2014-04-30 Байер Конзумер Кэр Аг A pharmaceutical composition
WO2010109256A1 (en) * 2009-03-23 2010-09-30 Carlo Ghisalberti Enhanced treatment of joint and connective tissue damage
RU2478376C1 (en) * 2011-11-24 2013-04-10 Общество С Ограниченной Ответственностью "Консорциум-Пик" Pharmaceutical composition based on vegetative dha for treating and preventing diseases of joints
EP2797584B1 (en) * 2011-12-27 2015-12-16 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Combinations of diacerein and non-steroidal inflammation drugs

Also Published As

Publication number Publication date
WO2019004868A3 (en) 2019-02-07
WO2019004868A2 (en) 2019-01-03
RU2017123275A3 (en) 2019-01-09
RU2742172C2 (en) 2021-02-02

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HE9A Changing address for correspondence with an applicant
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20191030

FZ9A Application not withdrawn (correction of the notice of withdrawal)

Effective date: 20201021