RU2017112763A - MEASURED DOSING METHOD AND ITS MECHANISMS - Google Patents

MEASURED DOSING METHOD AND ITS MECHANISMS Download PDF

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Publication number
RU2017112763A
RU2017112763A RU2017112763A RU2017112763A RU2017112763A RU 2017112763 A RU2017112763 A RU 2017112763A RU 2017112763 A RU2017112763 A RU 2017112763A RU 2017112763 A RU2017112763 A RU 2017112763A RU 2017112763 A RU2017112763 A RU 2017112763A
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Russia
Prior art keywords
working substance
cartridge
plunger
inner hole
possibility
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RU2017112763A
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Russian (ru)
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RU2017112763A3 (en
RU2685686C2 (en
Inventor
Аарон КЕНДЦИОРЕК
Николас Грейсон САЛЛИВАН
Сице ЭЛЬЗИНГА
Бредли Дж. ДУГЛАС
Джеффри Чарльз РАБЕР
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Сайнтифик Холдингс, Ллс
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Publication of RU2017112763A publication Critical patent/RU2017112763A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
    • B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
    • B05C17/01—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes with manually mechanically or electrically actuated piston or the like
    • B05C17/0116—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes with manually mechanically or electrically actuated piston or the like characterised by the piston driving means
    • B05C17/012—Stepwise advancing mechanism, e.g. pawl and ratchets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves

Claims (34)

1. Устройство для выдачи в дозированном количестве рабочего вещества, содержащее:1. A device for dispensing in a metered amount of a working substance, containing: корпус картриджа, имеющий проксимальный конец, дистальный конец и внутреннее отверстие и выполненный с возможностью размещения в нем сменного картриджа, содержащего пробку картриджа и рабочее вещество;a cartridge case having a proximal end, a distal end and an inner hole and configured to accommodate a replaceable cartridge containing a cartridge stopper and a working substance; кончик канала для выдавливания на проксимальном конце корпуса картриджа, причем верхняя часть содержит проточный канал для текучей среды; иthe tip of the channel for extrusion at the proximal end of the cartridge housing, the upper part containing a flow channel for a fluid; and продвигающий элемент, выполненный с возможностью посадки во внутреннее отверстие и с возможностью осевого перемещения через это отверстие;a promoting element configured to fit into the inner hole and with the possibility of axial movement through this hole; причем при перемещении продвигающего элемента по направлению к проксимальному концу корпуса продвигающий элемент выталкивает дозированное количество рабочего вещества через кончик канала для выдавливания;moreover, when moving the promoting element towards the proximal end of the housing, the promoting element pushes a metered amount of the working substance through the tip of the extrusion channel; при этом устройство также содержит штырек с множеством округлых выступов и винтовую пружину, выполненную с возможностью оказания давления на штырек с множеством округлых выступов;however, the device also contains a pin with many rounded protrusions and a coil spring, made with the possibility of applying pressure to the pin with many rounded protrusions; причем элемент ручной манипуляции содержит поворачиваемые вручную элементы, выполненные с возможностью продвижения плунжера через внутреннее отверстие при повороте;moreover, the element of manual manipulation contains manually rotatable elements configured to advance the plunger through the inner hole when turning; а картридж содержит рабочее вещество, пробку плунжера и клапан управления текучей средой, выполненный по меньшей мере в виде одного из однонаправленного и двунаправленного клапана, а также выполненный с возможностью открытия в ответ на давление внутри картриджа.and the cartridge contains a working substance, a plug of the plunger and a fluid control valve made in at least one of the unidirectional and bidirectional valves, and also made with the possibility of opening in response to pressure inside the cartridge. 2. Устройство для выдачи в дозированном количестве рабочего вещества, содержащее:2. A device for dispensing in a metered amount of a working substance, containing: корпус картриджа, имеющий проксимальный конец, дистальный конец и внутреннее отверстие и выполненный с возможностью размещения в нем сменного картриджа, содержащего пробку картриджа и рабочее вещество;a cartridge case having a proximal end, a distal end and an inner hole and configured to accommodate a replaceable cartridge containing a cartridge stopper and a working substance; кончик канала для выдавливания на проксимальном конце корпуса картриджа, причем верхняя часть содержит проточный канал для текучей среды; иthe tip of the channel for extrusion at the proximal end of the cartridge housing, the upper part containing a flow channel for a fluid; and продвигающий элемент, выполненный с возможностью посадки во внутреннее отверстие и с возможностью осевого перемещения через это отверстие;a promoting element configured to fit into the inner hole and with the possibility of axial movement through this hole; причем при перемещении продвигающего элемента по направлению к проксимальному концу корпуса продвигающий элемент выталкивает дозированное количество рабочего вещества через кончик канала для выдавливания;moreover, when moving the promoting element towards the proximal end of the housing, the promoting element pushes a metered amount of the working substance through the tip of the extrusion channel; при этом устройство также содержит штырек с множеством округлых выступов и винтовую пружину, выполненную с возможностью оказания давления на штырек с множеством округлых выступов;however, the device also contains a pin with many rounded protrusions and a coil spring, made with the possibility of applying pressure to the pin with many rounded protrusions; причем элемент ручной манипуляции содержит поворачиваемые вручную элементы, выполненные с возможностью продвижения плунжера через внутреннее отверстие при повороте;moreover, the element of manual manipulation contains manually rotatable elements configured to advance the plunger through the inner hole when turning; а картридж содержит рабочее вещество, пробку плунжера и клапан управления текучей средой, выполненный по меньшей мере в виде одного из однонаправленного и двунаправленного клапана, а также выполненный с возможностью открытия в ответ на давление внутри картриджа;and the cartridge contains a working substance, a plunger plug and a fluid control valve, made at least in the form of one of a unidirectional and bidirectional valve, and also made with the possibility of opening in response to pressure inside the cartridge; при этом устройство также содержит пробку картриджа, связанную с плунжером и выполненную с возможностью образования уплотнения с внутренним диаметром внутреннего отверстия и с возможностью проталкивания рабочего вещества через клапан управления текучей средой при продвижении плунжера.however, the device also contains a cartridge plug connected with the plunger and configured to form a seal with an inner diameter of the inner hole and with the possibility of pushing the working substance through the fluid control valve while advancing the plunger. 3. Устройство по п. 1, в котором продвигающий элемент выполнен с возможностью его электронного управления;3. The device according to claim 1, in which the promoting element is made with the possibility of its electronic control; причем продвигающим элементом может управлять удаленный оператор; аmoreover, the remote operator can control the promoting element; but устройство выполнено с возможностью доставки одного или более рабочих веществ в дозированном количестве, задаваемом удаленным оператором.the device is configured to deliver one or more working substances in a metered amount specified by a remote operator. 4. Устройство по п. 3, в котором продвигающим элементом управляют посредством давления, обеспечиваемого пневматической системой, также содержащее электронный нагревательный элемент.4. The device according to claim 3, in which the promoting element is controlled by the pressure provided by the pneumatic system, also containing an electronic heating element. 5. Способ выдачи в дозированном количестве рабочего вещества, включающий:5. A method of dispensing in a metered amount of a working substance, including: обеспечение устройства для выдачи в дозированном количестве рабочего вещества, содержащего:providing a device for dispensing in a metered amount of a working substance containing: по меньшей мере корпус картриджа, содержащий внутреннее отверстие;at least a cartridge housing comprising an inner hole; продвигающий элемент;promotion element; продвигаемый стопор; иadvanced stopper; and введение по меньшей мере одного или двух сменных картриджей, содержащих рабочее вещество, в устройство; иintroducing at least one or two replaceable cartridges containing the working substance into the device; and перемещение продвигающего элемента на отмеренное расстояние через внутреннее отверстие, что приводит к выдаче из устройства рабочего вещества в дозированном количестве.moving the promoting element at a measured distance through the inner hole, which leads to the issuance of the working substance from the device in a metered amount. 6. Способ по п. 5, в котором плунжер продвигают вручную.6. The method according to p. 5, in which the plunger is advanced manually. 7. Способ по п. 5, в котором плунжер продвигают электронно.7. The method of claim 5, wherein the plunger is electronically advanced. 8. Способ по п. 5, в котором плунжер продвигают посредством давления, обеспечиваемого пневматической системой.8. The method according to p. 5, in which the plunger is advanced through the pressure provided by the pneumatic system. 9. Способ по п. 5, в котором отмеренное расстояние задано видимой градуированной шкалой.9. The method according to p. 5, in which the measured distance is set by the visible graduated scale. 10. Способ по п. 5, также включающий регулировку продвигаемого стопора с приведением его в местоположение относительно продвигающего элемента,10. The method according to p. 5, also comprising adjusting the advancement stopper bringing it to a location relative to the advancement element, причем продвигаемый стопор ограничивает диапазон перемещения продвигающего элемента и, следовательно, ограничивает количество рабочего вещества, выпускаемого из устройства.moreover, the advance stop limits the range of movement of the advance element and, therefore, limits the amount of working substance discharged from the device.
RU2017112763A 2014-10-13 2015-10-13 Method of dispensed distribution and mechanism therefor RU2685686C2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462063198P 2014-10-13 2014-10-13
US62/063,198 2014-10-13
PCT/US2015/055272 WO2016061062A1 (en) 2014-10-13 2015-10-13 Metered dosing method and mechanisms thereof

Publications (3)

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RU2017112763A3 RU2017112763A3 (en) 2018-11-15
RU2017112763A true RU2017112763A (en) 2018-11-15
RU2685686C2 RU2685686C2 (en) 2019-04-22

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JP (1) JP6507237B2 (en)
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CA (1) CA2964457A1 (en)
CZ (1) CZ2017259A3 (en)
ES (1) ES2638007R1 (en)
GB (1) GB2547831A (en)
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ES2638007R1 (en) 2017-11-06
ES2638007A2 (en) 2017-10-18
AU2015333703B2 (en) 2018-12-13
IL251660B (en) 2020-05-31
RU2017112763A3 (en) 2018-11-15
GB201707675D0 (en) 2017-06-28
GB2547831A (en) 2017-08-30
WO2016061062A1 (en) 2016-04-21
RU2685686C2 (en) 2019-04-22
CA2964457A1 (en) 2016-04-21
JP6507237B2 (en) 2019-04-24
JP2017531499A (en) 2017-10-26
CZ2017259A3 (en) 2017-08-30
AU2015333703A1 (en) 2017-04-27
IL251660A0 (en) 2017-06-29

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