RU2017104909A3 - - Google Patents

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Publication number
RU2017104909A3
RU2017104909A3 RU2017104909A RU2017104909A RU2017104909A3 RU 2017104909 A3 RU2017104909 A3 RU 2017104909A3 RU 2017104909 A RU2017104909 A RU 2017104909A RU 2017104909 A RU2017104909 A RU 2017104909A RU 2017104909 A3 RU2017104909 A3 RU 2017104909A3
Authority
RU
Russia
Application number
RU2017104909A
Other languages
Russian (ru)
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RU2704811C2 (ru
RU2017104909A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2017104909A publication Critical patent/RU2017104909A/ru
Publication of RU2017104909A3 publication Critical patent/RU2017104909A3/ru
Application granted granted Critical
Publication of RU2704811C2 publication Critical patent/RU2704811C2/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/244Lanthanides; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
RU2017104909A 2014-07-17 2015-07-17 Лечение рака комбинацией лучевой терапии, наночастиц оксида церия и химиотерапевтического средства RU2704811C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462025861P 2014-07-17 2014-07-17
US62/025,861 2014-07-17
PCT/US2015/040869 WO2016011328A1 (en) 2014-07-17 2015-07-17 Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2019133284A Division RU2019133284A (ru) 2014-07-17 2015-07-17 Лечение рака комбинацией лучевой терапии, наночастиц оксида церия и химиотерапевтического средства

Publications (3)

Publication Number Publication Date
RU2017104909A RU2017104909A (ru) 2018-08-17
RU2017104909A3 true RU2017104909A3 (enExample) 2019-01-28
RU2704811C2 RU2704811C2 (ru) 2019-10-31

Family

ID=55079076

Family Applications (2)

Application Number Title Priority Date Filing Date
RU2017104909A RU2704811C2 (ru) 2014-07-17 2015-07-17 Лечение рака комбинацией лучевой терапии, наночастиц оксида церия и химиотерапевтического средства
RU2019133284A RU2019133284A (ru) 2014-07-17 2015-07-17 Лечение рака комбинацией лучевой терапии, наночастиц оксида церия и химиотерапевтического средства

Family Applications After (1)

Application Number Title Priority Date Filing Date
RU2019133284A RU2019133284A (ru) 2014-07-17 2015-07-17 Лечение рака комбинацией лучевой терапии, наночастиц оксида церия и химиотерапевтического средства

Country Status (9)

Country Link
EP (2) EP3628308A1 (enExample)
JP (2) JP6706255B2 (enExample)
CN (2) CN111184733A (enExample)
AU (1) AU2015289504B2 (enExample)
BR (1) BR112017000800A8 (enExample)
CA (1) CA2955384C (enExample)
MX (1) MX387363B (enExample)
RU (2) RU2704811C2 (enExample)
WO (1) WO2016011328A1 (enExample)

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US10512761B2 (en) 2009-12-02 2019-12-24 Renovorx, Inc. Methods for delivery of therapeutic materials to treat pancreatic cancer
WO2014197362A1 (en) 2013-06-03 2014-12-11 Ramtin Agah Devices, methods and kits for delivery of therapeutic materials to a pancreas
AU2015289504B2 (en) * 2014-07-17 2020-12-17 BioCurity Pharmaceuticals Inc. Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent
WO2017174437A1 (en) * 2016-04-05 2017-10-12 Hospital Clínic De Barcelona Ceria nanoparticles for use in the treatment of hepatocellular carcinoma
WO2018134254A1 (en) 2017-01-17 2018-07-26 Heparegenix Gmbh Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death
CA3063115A1 (en) * 2017-04-12 2018-10-18 Vikash J. BHAGWANDIN Compositions, packaged pharmaceuticals, and methods of using posaconazole for the sensitization of resistant tumors
AU2018258663B2 (en) * 2017-04-28 2022-08-04 Seagen Inc. Treatment of HER2 positive cancers
US12290564B2 (en) 2017-05-18 2025-05-06 Renovorx, Inc. Methods and apparatuses for treating tumors
US10695543B2 (en) 2017-05-18 2020-06-30 Renovorx, Inc. Methods for treating cancerous tumors
US11052224B2 (en) 2017-05-18 2021-07-06 Renovorx, Inc. Methods for treating cancerous tumors
WO2019124603A1 (ko) * 2017-12-22 2019-06-27 경상대학교병원 Iwr-1을 유효성분으로 함유하는 켈로이드 예방 또는 치료용 조성물
KR102102535B1 (ko) * 2018-07-26 2020-04-21 서울대학교산학협력단 방사선 보호 나노입자
WO2020069292A1 (en) * 2018-09-28 2020-04-02 The Regents Of The University Of Colorado, A Body Corporate Methods for preventing and treating pulmonary inflammation and fibrosis
RU2699670C1 (ru) * 2018-11-16 2019-09-09 Объединенный Институт Ядерных Исследований (Оияи) Способ повышения частоты образования двунитевых разрывов днк в клетках человека при действии ионизирующих излучений в условиях влияния радиомодификаторов
CN115996633A (zh) * 2020-04-30 2023-04-21 中佛罗里达大学研究基金会 消毒用可分配的纳米颗粒基组合物
JP2024531479A (ja) 2021-08-27 2024-08-29 アセンタウィッツ ファーマシューティカルズ リミテッド 凍結乾燥製剤溶液および凍結乾燥製剤、ならびにそれらの方法および使用
JP7762796B2 (ja) 2021-08-27 2025-10-30 アセンタウィッツ ファーマシューティカルズ リミテッド Parp阻害剤に耐性のある患者のth-302による治療
US20250186468A1 (en) 2022-03-15 2025-06-12 Ascentawits Pharmaceuticals, Ltd. Method for treating patient with brca-mutated cancer
EP4509127A1 (en) 2022-04-15 2025-02-19 Ascentawits Pharmaceuticals, Ltd. Method for treating cancer by using th-302 alone or in combination with parp inhibitor
EP4529926A1 (en) 2022-05-23 2025-04-02 Ascentawits Pharmaceuticals, Ltd. Method for treating cancer by combining alkylating agent prodrug and cell cycle inhibitor
CN119894521A (zh) 2022-09-22 2025-04-25 深圳艾欣达伟医药科技有限公司 乏氧激活的化合物在制备治疗癌症患者的药物中的用途

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099798A (en) 1997-10-31 2000-08-08 Nanogram Corp. Ultraviolet light block and photocatalytic materials
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
EP1904072A4 (en) * 2005-06-27 2009-06-17 Edward Via Virginia College Of ANTI-INFLAMMATORY, RADIOPROTECTIVE CERTIFICATE OXIDE NANOPARTICLE CAPACITIES AND ENHANCING LONGEVITY
CA2710377A1 (en) * 2007-12-27 2009-07-09 Infinity Pharmaceuticals, Inc. Therapeutic cancer treatments
EP2288258A4 (en) * 2008-04-25 2012-10-31 Univ Oklahoma INHIBITION OF NEOVASCULARIZATION BY CERIUM OXIDE NANOPARTICLES
US20100015042A1 (en) * 2008-07-03 2010-01-21 Ramot At Tel Aviv University Ltd. Combine radiation therapy and chemotherapy for treating cancer
GB0921596D0 (en) * 2009-12-09 2010-01-27 Isis Innovation Particles for the treatment of cancer in combination with radiotherapy
CN102933258A (zh) * 2010-03-01 2013-02-13 因特奥普医药公司 与含氧量低的细胞敏化剂联用的放疗
US20120251496A1 (en) * 2011-03-31 2012-10-04 Telik, Inc. Ezatiostat for treating multiple myeloma
CA2869554A1 (en) * 2012-04-04 2013-10-10 Duke University Methods of using cerium oxide nanoparticles to mitigate or protect against radiation injury
JP6174692B2 (ja) * 2012-06-13 2017-08-02 セリオン エンタープライジズ リミテッド ライアビリティ カンパニー 酸化ストレスの処置のためのナノセリア
EP2928877B1 (en) * 2012-12-06 2020-01-22 Merck Sharp & Dohme Corp. Disulfide masked prodrug compositions and methods
WO2015164780A1 (en) * 2014-04-25 2015-10-29 The Regents Of The University Of Michigan Nanoparticle therapy in cancer
AU2015289504B2 (en) * 2014-07-17 2020-12-17 BioCurity Pharmaceuticals Inc. Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent
GB201506381D0 (en) * 2015-04-15 2015-05-27 Isis Innovation Embolization particle

Also Published As

Publication number Publication date
CN111184733A (zh) 2020-05-22
EP3628308A1 (en) 2020-04-01
JP2017521499A (ja) 2017-08-03
CN106604719B (zh) 2019-11-26
EP3169312A4 (en) 2017-12-27
MX2017000578A (es) 2017-07-20
WO2016011328A1 (en) 2016-01-21
EP3169312B1 (en) 2020-09-02
RU2019133284A (ru) 2019-12-05
CA2955384A1 (en) 2016-01-21
CA2955384C (en) 2024-03-12
BR112017000800A8 (pt) 2023-04-25
JP2020158507A (ja) 2020-10-01
EP3169312A1 (en) 2017-05-24
AU2015289504A1 (en) 2017-02-23
RU2704811C2 (ru) 2019-10-31
CN106604719A (zh) 2017-04-26
RU2017104909A (ru) 2018-08-17
JP6706255B2 (ja) 2020-06-03
MX387363B (es) 2025-03-18
AU2015289504B2 (en) 2020-12-17
BR112017000800A2 (pt) 2018-07-03

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