RU2015142664A - NODE FOR DEVICE FOR DELIVERY OF MEDICINES - Google Patents

NODE FOR DEVICE FOR DELIVERY OF MEDICINES Download PDF

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Publication number
RU2015142664A
RU2015142664A RU2015142664A RU2015142664A RU2015142664A RU 2015142664 A RU2015142664 A RU 2015142664A RU 2015142664 A RU2015142664 A RU 2015142664A RU 2015142664 A RU2015142664 A RU 2015142664A RU 2015142664 A RU2015142664 A RU 2015142664A
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RU
Russia
Prior art keywords
dose
piston rod
node according
during
drive element
Prior art date
Application number
RU2015142664A
Other languages
Russian (ru)
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RU2015142664A3 (en
RU2673378C2 (en
Inventor
Дэвид Обри Пламптр
Роберт Фредерик Виси
Original Assignee
Санофи-Авентис Дойчланд Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of RU2015142664A publication Critical patent/RU2015142664A/en
Publication of RU2015142664A3 publication Critical patent/RU2015142664A3/ru
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Publication of RU2673378C2 publication Critical patent/RU2673378C2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback

Claims (16)

1. Узел (30) для устройства (1) доставки лекарств, содержащий:1. An assembly (30) for a drug delivery device (1), comprising: - исполнительный элемент (16), который выполнен с возможностью установочного перемещения в проксимальном направлении для установки дозы лекарства, и который выполнен с возможностью выдачного перемещения в дистальном направлении для выдачи дозы лекарства,- an actuating element (16), which is configured to move in the proximal direction to set the dose of the drug, and which is configured to dispense in the distal direction to dispense the dose of medicine, - стопорный механизм (40), срабатывающий после того, как доставлено максимальное количество лекарства, и который выполнен с возможностью такого аксиального ограничения установочного перемещения исполнительного элемента (16), что установка дозы блокируется, при этом ограниченное аксиальное перемещение исполнительного элемента (16) допускается,- a locking mechanism (40) that is activated after the maximum quantity of medication has been delivered, and which is configured to axially restrict the positioning of the actuator (16) so that the dose is blocked, with limited axial movement of the actuator (16), - поршневой шток (10), причем поршневой шток (10) содержит упор (37) последней дозы, и при этом стопорный механизм (40) содержит стопорный элемент (27), причем перемещение исполнительного элемента (16) в проксимальном направлении блокируется, когда стопорный элемент (27) упирается в упор (37) последней дозы,- a piston rod (10), and the piston rod (10) contains the stop (37) of the last dose, and the locking mechanism (40) contains a locking element (27), and the movement of the actuating element (16) in the proximal direction is blocked when the locking element (27) abuts against the stop (37) of the last dose, - приводной элемент (14), который выполнен с возможностью перемещения вдоль поршневого штока (10) в проксимальном направлении для установки дозы, причем приводной элемент (14) выполнен с возможностью перемещения поршневого штока (10) в направлении к выдачному концу устройства во время выдачи дозы, причем стопорный элемент (27) расположен на внутренней поверхности приводного элемента (14), причем поршневой шток (10) содержит направляющий элемент (26), причем направляющий элемент (26) и стопорный элемент (27) выполнены с возможностью такого взаимодействия, что поворот поршневого штока (10) во время установки дозы блокируется, а поворот поршневого штока (10) во время выдачи дозы допускается.- a drive element (14), which is configured to move along the piston rod (10) in the proximal direction for setting the dose, and the drive element (14) is configured to move the piston rod (10) towards the dispensing end of the device during the dose moreover, the locking element (27) is located on the inner surface of the drive element (14), and the piston rod (10) contains a guide element (26), and the guide element (26) and the locking element (27) are made with the possibility of such interaction That rotation of the piston rod (10) during dose setting is blocked, and the rotation of the piston rod (10) during dispensing doses permitted. 2. Узел по п. 1, в котором упор (37) последней дозы имеет форму углубления, которое, по меньшей мере, частично охватывает стопорный элемент (27).2. The assembly according to claim 1, wherein the stop (37) of the last dose has the form of a recess, which at least partially covers the locking element (27). 3. Узел по п. 1, в котором приводной элемент (14) связан с исполнительным элементом (16) таким образом, что перемещение приводного элемента (14) приводит к перемещению исполнительного элемента (16) и наоборот.3. The node according to claim 1, in which the drive element (14) is connected with the actuating element (16) so that the movement of the drive element (14) leads to the movement of the actuating element (16) and vice versa. 4. Узел по п. 1, в котором направляющий элемент (26) и стопорный элемент (27) упираются друг в друга во время установки дозы.4. The node according to claim 1, in which the guide element (26) and the locking element (27) abut against each other during dose setting. 5. Узел по п. 1, в котором направляющий элемент (26) и стопорный элемент (27) выполнены с возможностью прохода одного мимо другого во время выдачи дозы.5. The node according to claim 1, in which the guide element (26) and the locking element (27) are made with the possibility of passing one past the other during the dose. 6. Узел по п. 1, в котором направляющий элемент (26) содержит множество шпонок (28).6. The node according to claim 1, in which the guide element (26) contains many keys (28). 7. Узел по п. 6, в котором направляющий элемент (26) содержит три ряда шпонок (28), которые равномерно распределены по внешней окружности поршневого штока (10).7. The node according to claim 6, in which the guide element (26) contains three rows of dowels (28) that are evenly distributed around the outer circumference of the piston rod (10). 8. Узел по п. 6 или 7, в котором стопорный элемент (27) находится в контакте с, по меньшей мере, одной шпонкой (28) направляющего элемента (26) во время перемещения установки дозы приводного элемента (14).8. The assembly according to claim 6 or 7, in which the locking element (27) is in contact with at least one key (28) of the guide element (26) while moving the dose setting of the drive element (14). 9. Узел по п. 1, в котором приводной элемент (14) выполняет аксиальное, невращательное перемещение по время установки и выдачи дозы.9. The node according to claim 1, in which the drive element (14) performs axial, non-rotational movement during installation and delivery of the dose. 10. Узел по п. 1, в котором аксиальное смещение приводного элемента (14) во время выдачи дозы больше аксиального смещения поршневого штока (10) во время выдачи дозы.10. The assembly according to claim 1, wherein the axial displacement of the drive element (14) during dose delivery is greater than the axial displacement of the piston rod (10) during dose delivery. 11. Узел по п. 1, в котором перемещение поршневого штока (10) блокируется во время установки дозы.11. The node according to claim 1, in which the movement of the piston rod (10) is blocked during dose setting. 12. Узел по любому из пп. 1-7, 9-11, в котором перемещение приводного элемента (14) в дистальном направлении к выдачному концу устройства вынуждает поршневой шток (10) вращаться и аксиально перемещаться к дистальному концу устройства.12. The node according to any one of paragraphs. 1-7, 9-11, in which moving the drive element (14) in the distal direction to the dispensing end of the device causes the piston rod (10) to rotate and axially move to the distal end of the device.
RU2015142664A 2013-03-11 2014-03-10 Assembly for drug delivery device RU2673378C2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13158512 2013-03-11
EP13158512.7 2013-03-11
PCT/EP2014/054521 WO2014139910A1 (en) 2013-03-11 2014-03-10 Assembly for a drug delivery device

Publications (3)

Publication Number Publication Date
RU2015142664A true RU2015142664A (en) 2017-04-25
RU2015142664A3 RU2015142664A3 (en) 2018-03-12
RU2673378C2 RU2673378C2 (en) 2018-11-26

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Application Number Title Priority Date Filing Date
RU2015142664A RU2673378C2 (en) 2013-03-11 2014-03-10 Assembly for drug delivery device

Country Status (18)

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US (1) US10201663B2 (en)
EP (1) EP2968781B1 (en)
JP (1) JP6352316B2 (en)
KR (1) KR102282541B1 (en)
CN (1) CN105025963B (en)
AR (1) AR095194A1 (en)
AU (1) AU2014231036B2 (en)
DK (1) DK2968781T3 (en)
ES (1) ES2735329T3 (en)
HK (1) HK1213511A1 (en)
HU (1) HUE044075T2 (en)
IL (1) IL240546B (en)
MX (1) MX363431B (en)
PL (1) PL2968781T3 (en)
RU (1) RU2673378C2 (en)
TR (1) TR201910216T4 (en)
TW (1) TWI644693B (en)
WO (1) WO2014139910A1 (en)

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Publication number Publication date
HK1213511A1 (en) 2016-07-08
PL2968781T3 (en) 2019-09-30
TR201910216T4 (en) 2019-08-21
EP2968781B1 (en) 2019-04-24
MX2015012571A (en) 2016-01-12
ES2735329T3 (en) 2019-12-18
IL240546B (en) 2020-04-30
KR20150126927A (en) 2015-11-13
EP2968781A1 (en) 2016-01-20
BR112015020816A2 (en) 2017-07-18
JP6352316B2 (en) 2018-07-04
RU2015142664A3 (en) 2018-03-12
HUE044075T2 (en) 2019-09-30
MX363431B (en) 2019-03-22
CN105025963A (en) 2015-11-04
DK2968781T3 (en) 2019-07-15
IL240546A0 (en) 2015-10-29
US20160008551A1 (en) 2016-01-14
CN105025963B (en) 2019-12-03
AR095194A1 (en) 2015-09-30
AU2014231036A1 (en) 2015-09-24
TW201509457A (en) 2015-03-16
TWI644693B (en) 2018-12-21
JP2016509896A (en) 2016-04-04
RU2673378C2 (en) 2018-11-26
AU2014231036B2 (en) 2018-07-05
KR102282541B1 (en) 2021-07-29
WO2014139910A1 (en) 2014-09-18
US10201663B2 (en) 2019-02-12

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