RU2010136488A - METHOD FOR STABILIZING ANTIBODIES IN AQUEOUS SOLUTIONS - Google Patents
METHOD FOR STABILIZING ANTIBODIES IN AQUEOUS SOLUTIONS Download PDFInfo
- Publication number
- RU2010136488A RU2010136488A RU2010136488/15A RU2010136488A RU2010136488A RU 2010136488 A RU2010136488 A RU 2010136488A RU 2010136488/15 A RU2010136488/15 A RU 2010136488/15A RU 2010136488 A RU2010136488 A RU 2010136488A RU 2010136488 A RU2010136488 A RU 2010136488A
- Authority
- RU
- Russia
- Prior art keywords
- aqueous solutions
- antibodies
- stabilizing antibodies
- alkyloxybenzene
- methylresorcinol
- Prior art date
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Abstract
Способ стабилизации антител в водных растворах, заключающийся во введении в раствор антител модифицирующей добавки - C1-алкилоксибензола (метилрезорцина) в концентрации 10-4 М (0,0124 г/л) в соотношении 1:1 и хранении в герметично упакованных стеклянных емкостях при температуре от +4°С до +37°С с последующим использованием для постановки соответствующих иммунологических реакций. The method of stabilization of antibodies in aqueous solutions, which consists in introducing into the antibody solution a modifying additive - C1-alkyloxybenzene (methylresorcinol) at a concentration of 10-4 M (0.0124 g / l) in a ratio of 1: 1 and storage in sealed glass containers at a temperature from + 4 ° C to + 37 ° C, followed by use for the formulation of appropriate immunological reactions.
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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RU2010136488/15A RU2447448C1 (en) | 2010-08-30 | 2010-08-30 | Method for stabilising antibodies in aqueous solutions |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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RU2010136488/15A RU2447448C1 (en) | 2010-08-30 | 2010-08-30 | Method for stabilising antibodies in aqueous solutions |
Publications (2)
Publication Number | Publication Date |
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RU2010136488A true RU2010136488A (en) | 2012-03-10 |
RU2447448C1 RU2447448C1 (en) | 2012-04-10 |
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Family Applications (1)
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RU2010136488/15A RU2447448C1 (en) | 2010-08-30 | 2010-08-30 | Method for stabilising antibodies in aqueous solutions |
Country Status (1)
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RU (1) | RU2447448C1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2707092C2 (en) * | 2013-03-13 | 2019-11-22 | Дженентек, Инк. | Compositions with reduced oxidation |
US10653779B2 (en) | 2013-03-13 | 2020-05-19 | Genentech, Inc. | Formulations with reduced oxidation |
US11596620B2 (en) | 2013-03-13 | 2023-03-07 | F. Hoffmann-La Roche Ag | Formulations with reduced oxidation |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2238318C1 (en) * | 2003-06-20 | 2004-10-20 | Открытое акционерное общество "Восток" | Method for stabilization and activation of hydrolytic enzymes |
-
2010
- 2010-08-30 RU RU2010136488/15A patent/RU2447448C1/en not_active IP Right Cessation
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2707092C2 (en) * | 2013-03-13 | 2019-11-22 | Дженентек, Инк. | Compositions with reduced oxidation |
US10653779B2 (en) | 2013-03-13 | 2020-05-19 | Genentech, Inc. | Formulations with reduced oxidation |
US11596620B2 (en) | 2013-03-13 | 2023-03-07 | F. Hoffmann-La Roche Ag | Formulations with reduced oxidation |
Also Published As
Publication number | Publication date |
---|---|
RU2447448C1 (en) | 2012-04-10 |
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Legal Events
Date | Code | Title | Description |
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MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20120831 |