RU2010135831A - Способы, лекарственные формы и наборы для введения зипрасидона без пищи - Google Patents
Способы, лекарственные формы и наборы для введения зипрасидона без пищи Download PDFInfo
- Publication number
- RU2010135831A RU2010135831A RU2010135831/15A RU2010135831A RU2010135831A RU 2010135831 A RU2010135831 A RU 2010135831A RU 2010135831/15 A RU2010135831/15 A RU 2010135831/15A RU 2010135831 A RU2010135831 A RU 2010135831A RU 2010135831 A RU2010135831 A RU 2010135831A
- Authority
- RU
- Russia
- Prior art keywords
- ziprasidone
- dosage form
- serum
- oral dosage
- solid oral
- Prior art date
Links
- MVWVFYHBGMAFLY-UHFFFAOYSA-N ziprasidone Chemical compound C1=CC=C2C(N3CCN(CC3)CCC3=CC=4CC(=O)NC=4C=C3Cl)=NSC2=C1 MVWVFYHBGMAFLY-UHFFFAOYSA-N 0.000 title claims abstract 69
- 229960000607 ziprasidone Drugs 0.000 title claims abstract 69
- 238000000034 method Methods 0.000 title claims abstract 19
- 239000006186 oral dosage form Substances 0.000 claims abstract 25
- 239000007787 solid Substances 0.000 claims abstract 25
- 210000002966 serum Anatomy 0.000 claims abstract 22
- 208000015114 central nervous system disease Diseases 0.000 claims abstract 12
- 210000002784 stomach Anatomy 0.000 claims abstract 10
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims abstract 9
- 239000002775 capsule Substances 0.000 claims abstract 3
- 210000003169 central nervous system Anatomy 0.000 claims abstract 2
- 239000002552 dosage form Substances 0.000 claims 9
- 239000008247 solid mixture Substances 0.000 claims 5
- 230000003111 delayed effect Effects 0.000 claims 3
- 238000004090 dissolution Methods 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 229920000639 hydroxypropylmethylcellulose acetate succinate Polymers 0.000 claims 3
- 238000013268 sustained release Methods 0.000 claims 3
- 239000012730 sustained-release form Substances 0.000 claims 3
- ZUAAPNNKRHMPKG-UHFFFAOYSA-N acetic acid;butanedioic acid;methanol;propane-1,2-diol Chemical compound OC.CC(O)=O.CC(O)CO.OC(=O)CCC(O)=O ZUAAPNNKRHMPKG-UHFFFAOYSA-N 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 229940100691 oral capsule Drugs 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 238000001556 precipitation Methods 0.000 claims 2
- 229960003474 ziprasidone hydrochloride Drugs 0.000 claims 2
- ZCBZSCBNOOIHFP-UHFFFAOYSA-N ziprasidone hydrochloride hydrate Chemical compound [H+].O.[Cl-].C1=CC=C2C(N3CCN(CC3)CCC3=CC=4CC(=O)NC=4C=C3Cl)=NSC2=C1 ZCBZSCBNOOIHFP-UHFFFAOYSA-N 0.000 claims 2
- 229920000858 Cyclodextrin Polymers 0.000 claims 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 1
- 208000012902 Nervous system disease Diseases 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims 1
- 239000007939 sustained release tablet Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 229940095064 tartrate Drugs 0.000 claims 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3494708P | 2008-03-07 | 2008-03-07 | |
| US61/034,947 | 2008-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2010135831A true RU2010135831A (ru) | 2012-04-20 |
Family
ID=40720011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010135831/15A RU2010135831A (ru) | 2008-03-07 | 2009-03-04 | Способы, лекарственные формы и наборы для введения зипрасидона без пищи |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20110002989A1 (OSRAM) |
| EP (1) | EP2280711A1 (OSRAM) |
| JP (1) | JP2009215293A (OSRAM) |
| KR (1) | KR20100131477A (OSRAM) |
| CN (1) | CN102014910A (OSRAM) |
| AR (1) | AR070964A1 (OSRAM) |
| AU (1) | AU2009220925A1 (OSRAM) |
| BR (1) | BRPI0909818A2 (OSRAM) |
| CA (1) | CA2719115A1 (OSRAM) |
| IL (1) | IL207792A0 (OSRAM) |
| MX (1) | MX2010009844A (OSRAM) |
| RU (1) | RU2010135831A (OSRAM) |
| TW (1) | TW200950783A (OSRAM) |
| WO (1) | WO2009109844A1 (OSRAM) |
| ZA (1) | ZA201005905B (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010082855A1 (en) * | 2009-01-15 | 2010-07-22 | Zaklady Farmaceutyczne Polpharma Sa | Pharmaceutical compositions comprising ziprasidone free base or ziprasidone hydrochloride and the method for their preparation |
| US9510148B2 (en) * | 2009-03-03 | 2016-11-29 | Mobilitie, Llc | System and method for wireless communication to permit audience participation |
| KR102337598B1 (ko) * | 2013-05-03 | 2021-12-10 | 신닥스 파마슈티컬스, 인크. | 암 치료 방법 |
| MX2016001304A (es) | 2013-07-30 | 2016-04-07 | Gilead Connecticut Inc | Polimorfo de inhibidores de syk. |
| PT3027171T (pt) | 2013-07-30 | 2020-06-18 | Gilead Connecticut Inc | Formulação de inibidores da syk |
| WO2015082562A1 (en) * | 2013-12-05 | 2015-06-11 | Alrise Biosystems Gmbh | Process for the production of drug formulations for oral administration |
| TWI735853B (zh) | 2013-12-23 | 2021-08-11 | 美商克洛諾斯生技有限公司 | 脾酪胺酸激酶抑制劑 |
| US10474345B2 (en) * | 2014-04-04 | 2019-11-12 | Shawn SHEY | User interfaces and methods for displaying content |
| AU2015317468B2 (en) * | 2014-09-19 | 2018-06-14 | The Procter & Gamble Company | Process for making a core with an active coating |
| WO2016198983A1 (en) | 2015-06-09 | 2016-12-15 | Bend Research Inc. | Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules |
| CA2987081C (en) | 2015-06-11 | 2022-08-30 | Alrise Biosystems Gmbh | Process for the preparation of drug loaded microparticles |
| CN107714669A (zh) * | 2016-08-11 | 2018-02-23 | 广东东阳光药业有限公司 | 齐拉西酮缓释剂及其制备方法 |
| CN115028640A (zh) | 2017-08-25 | 2022-09-09 | 吉利德科学公司 | Syk抑制剂的多晶型物 |
| KR20210131372A (ko) | 2019-02-22 | 2021-11-02 | 크로노스 바이오, 인코포레이티드 | Syk 억제제로서의 축합된 피라진의 고체 형태 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003000226A2 (en) * | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions containing polymer and drug assemblies |
| BRPI0414082A (pt) * | 2003-09-02 | 2006-10-24 | Pfizer Prod Inc | formas de dosagem de liberação sustentada de ziprasidona |
| US7825106B2 (en) * | 2003-09-03 | 2010-11-02 | Agi Therapeutics Ltd. | Modified release formulations and methods of treating inflammatory bowel disease |
| WO2005065660A2 (en) * | 2003-12-31 | 2005-07-21 | Alpharma, Inc. | Ziprasidone formulations |
| WO2005123086A2 (en) * | 2004-06-11 | 2005-12-29 | Dr. Reddy's Laboratories Ltd. | Ziprasidone dosage form |
| EP1901722A4 (en) * | 2005-06-20 | 2011-06-15 | Elan Pharma Int Ltd | NANOTEHOUS COMPOSITIONS WITH CONTROLLED RELEASE FROM ARYL-HETEROCYCLIC COMPOUNDS |
-
2009
- 2009-03-04 US US12/920,400 patent/US20110002989A1/en not_active Abandoned
- 2009-03-04 TW TW098106972A patent/TW200950783A/zh unknown
- 2009-03-04 EP EP09717510A patent/EP2280711A1/en not_active Withdrawn
- 2009-03-04 CA CA2719115A patent/CA2719115A1/en not_active Abandoned
- 2009-03-04 KR KR1020107022343A patent/KR20100131477A/ko not_active Ceased
- 2009-03-04 WO PCT/IB2009/000442 patent/WO2009109844A1/en not_active Ceased
- 2009-03-04 RU RU2010135831/15A patent/RU2010135831A/ru not_active Application Discontinuation
- 2009-03-04 BR BRPI0909818A patent/BRPI0909818A2/pt not_active IP Right Cessation
- 2009-03-04 CN CN2009801164839A patent/CN102014910A/zh active Pending
- 2009-03-04 MX MX2010009844A patent/MX2010009844A/es not_active Application Discontinuation
- 2009-03-04 AU AU2009220925A patent/AU2009220925A1/en not_active Abandoned
- 2009-03-06 AR ARP090100819A patent/AR070964A1/es not_active Application Discontinuation
- 2009-03-06 JP JP2009052853A patent/JP2009215293A/ja not_active Withdrawn
-
2010
- 2010-08-18 ZA ZA2010/05905A patent/ZA201005905B/en unknown
- 2010-08-24 IL IL207792A patent/IL207792A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR070964A1 (es) | 2010-05-19 |
| MX2010009844A (es) | 2010-09-30 |
| EP2280711A1 (en) | 2011-02-09 |
| WO2009109844A1 (en) | 2009-09-11 |
| JP2009215293A (ja) | 2009-09-24 |
| BRPI0909818A2 (pt) | 2015-10-06 |
| CA2719115A1 (en) | 2009-09-11 |
| AU2009220925A1 (en) | 2009-09-11 |
| TW200950783A (en) | 2009-12-16 |
| CN102014910A (zh) | 2011-04-13 |
| US20110002989A1 (en) | 2011-01-06 |
| IL207792A0 (en) | 2010-12-30 |
| KR20100131477A (ko) | 2010-12-15 |
| ZA201005905B (en) | 2011-11-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2010135831A (ru) | Способы, лекарственные формы и наборы для введения зипрасидона без пищи | |
| US20220184222A1 (en) | Bicycle toxin conjugates and uses thereof | |
| JP6845162B2 (ja) | ケタミン経皮送達システム | |
| JP2022058678A (ja) | ブプレノルフィンの乱用抵抗性粘膜付着性送達デバイス | |
| Jain et al. | Evaluation of efficacy of oral pregabalin in reducing postoperative pain in patients undergoing total knee arthroplasty | |
| US7084116B2 (en) | Methods for treating lower urinary tract disorders and the related disorders vulvodynia and vulvar vestibulitis using Cav2.2 subunit calcium channel modulators | |
| JP2009215293A5 (OSRAM) | ||
| JP2020023518A5 (OSRAM) | ||
| US20210196653A1 (en) | Delivery Of Esketamine For The Treatment Of Depression | |
| US20240277608A1 (en) | Esketamine for the treatment of depression | |
| EP2248519A3 (en) | Non-mucoadhesive film dosage forms | |
| JP2018507243A5 (OSRAM) | ||
| JP2019517542A5 (OSRAM) | ||
| JP2016074728A (ja) | 脱髄性および他の神経系疾患を患っている患者における神経認知的および／または神経精神医学的障害を改善するための４−アミノピリジンの使用 | |
| JP2019530706A5 (OSRAM) | ||
| Gautam et al. | Evaluation of the efficacy of methylprednisolone, etoricoxib and a combination of the two substances to attenuate postoperative pain and PONV in patients undergoing laparoscopic cholecystectomy: a prospective, randomized, placebo-controlled trial | |
| JP4996803B2 (ja) | 抗高血圧剤に対する抵抗性及び関連状態を処置する方法及び処方物 | |
| JP2020500864A5 (OSRAM) | ||
| CN103370066A (zh) | 用于治疗癌症的包含威罗菲尼和干扰素的组合疗法 | |
| US20210353648A1 (en) | Grapiprant unit dosage forms | |
| RU2008102911A (ru) | Фармацевтические составы на основе гуанфацина, подходящие для ежедневного введения в виде единичной дозированной формы | |
| CN104936585B (zh) | 包括苯肾上腺素和扑热息痛的组合药剂 | |
| JP6420923B1 (ja) | 医薬 | |
| WO2021262749A1 (en) | Compositions and methods for preventing and/or treating viral infection | |
| RU2394559C2 (ru) | Способ установления неспецифического противоинфекционного действия иммуномодулирующего иммунобиологического препарата |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20121009 |