RU2010121106A - METHOD FOR TREATING LUNG CANCER - Google Patents
METHOD FOR TREATING LUNG CANCER Download PDFInfo
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- RU2010121106A RU2010121106A RU2010121106/15A RU2010121106A RU2010121106A RU 2010121106 A RU2010121106 A RU 2010121106A RU 2010121106/15 A RU2010121106/15 A RU 2010121106/15A RU 2010121106 A RU2010121106 A RU 2010121106A RU 2010121106 A RU2010121106 A RU 2010121106A
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- dose
- cytapheresis
- allogeneic
- session
- incubated
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Abstract
Способ лечения рака легкого, включающий противоопухолевую иммунотерапию, отличающийся тем, что больным с метастатическим поражением единственного легкого во время проведения аутогемохимиотерапии выполняют трансфузию аллогенной лимфолейкоцитарной массы, полученной от одногруппного донора; после стимуляции лейкопоэза донора нейпогеном в дозе 2,5 мкг/кг массы тела в течение 2-3 дней до достижения уровня лейкоцитов в периферической крови 20·10/9/л и проводят 2 сеанса лимфлейкоцитафереза 4,5 ОЦК, собирая взвесь в стерильные пластиковые контейнеры, полученную в результате сеанса цитафереза разделяют на 2 равные порции: 1-ю порцию инкубируют с ронколейкином в дозе 500.000 ME, 2-ю порцию инкубируют с лейкифероном в дозе 300.000 ЕД при температуре 37°С в течении 180 мин и внутривенно капельно вводят больному- реципиенту; аналогичную процедуру проводят через 24 ч, используя аллогенную лимфолейкоцитарную массу, полученную в результате второго сеанса цитафереза. A method for the treatment of lung cancer, including antitumor immunotherapy, characterized in that patients with metastatic lesion of a single lung during autohemochemotherapy perform transfusion of allogeneic lymphocytic mass obtained from a single group donor; after stimulation of donor leukopoiesis with a neupogen in a dose of 2.5 μg / kg body weight for 2-3 days until the level of leukocytes in peripheral blood reaches 20 · 10/9 / l and 2 sessions of lymphocytapheresis of 4.5 bcc are carried out, collecting the suspension in sterile plastic the containers obtained as a result of the cytapheresis session are divided into 2 equal portions: the 1st portion is incubated with roncoleukin in a dose of 500,000 ME, the 2nd portion is incubated with leuciferon in a dose of 300,000 IU at a temperature of 37 ° C for 180 minutes and administered intravenously to the patient - to the recipient; a similar procedure is carried out after 24 hours using an allogeneic lymphocytic leukocyte mass obtained as a result of the second session of cytapheresis.
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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RU2010121106/15A RU2463062C2 (en) | 2010-05-25 | 2010-05-25 | Method of treating lung cancer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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RU2010121106/15A RU2463062C2 (en) | 2010-05-25 | 2010-05-25 | Method of treating lung cancer |
Publications (2)
Publication Number | Publication Date |
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RU2010121106A true RU2010121106A (en) | 2011-11-27 |
RU2463062C2 RU2463062C2 (en) | 2012-10-10 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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RU2010121106/15A RU2463062C2 (en) | 2010-05-25 | 2010-05-25 | Method of treating lung cancer |
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RU (1) | RU2463062C2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2519738C2 (en) * | 2011-12-12 | 2014-06-20 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения и социального развития Российской Федерации | Method of treating lung cancer |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2107494C1 (en) * | 1993-05-06 | 1998-03-27 | Ростовский научно-исследовательский онкологический институт МЗ РФ | Method for treating pulmonary cancer |
RU2184555C2 (en) * | 1999-12-14 | 2002-07-10 | Ростовский научно-исследовательский онкологический институт | Method to treat pulmonary cancer |
RU2242998C1 (en) * | 2003-04-21 | 2004-12-27 | Ростовский научно-исследовательский онкологический институт | Method for treating pulmonary cancer |
RU2348420C2 (en) * | 2007-04-17 | 2009-03-10 | ФГУ Ростовский научно-исследовательский онкологический институт Росздрава | Method of treatment of locally advanced lung cancer |
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2010
- 2010-05-25 RU RU2010121106/15A patent/RU2463062C2/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2519738C2 (en) * | 2011-12-12 | 2014-06-20 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения и социального развития Российской Федерации | Method of treating lung cancer |
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RU2463062C2 (en) | 2012-10-10 |
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MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20120526 |