RU2009122169A - METHOD FOR PRODUCING SHELLS BASED ON CHITOZAN AND ALGINIC ACID SALTS FOR MICROCapsules CONTAINING PHOSPHOLIPIDIC MICELS - Google Patents
METHOD FOR PRODUCING SHELLS BASED ON CHITOZAN AND ALGINIC ACID SALTS FOR MICROCapsules CONTAINING PHOSPHOLIPIDIC MICELS Download PDFInfo
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- RU2009122169A RU2009122169A RU2009122169/05A RU2009122169A RU2009122169A RU 2009122169 A RU2009122169 A RU 2009122169A RU 2009122169/05 A RU2009122169/05 A RU 2009122169/05A RU 2009122169 A RU2009122169 A RU 2009122169A RU 2009122169 A RU2009122169 A RU 2009122169A
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- alkaline earth
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- Manufacturing Of Micro-Capsules (AREA)
Abstract
1. Способ получения оболочек на основе хитозана и солей альгиновой кислоты для микрокапсул, содержащих фосфолипидные мицеллы, характеризующийся последовательной выдержкой ядер микрокапсул в 0,5÷1,0% (вес./об.) растворе хитозана средней или низкой вязкости в 1,0% уксусной кислоте, в 2,5÷3,0% растворе хлорида щелочноземельного металла, в 0,5÷1,0% (вес./об.) растворе альгината натрия и, повторно, в 2,5÷3,0% растворе хлорида щелочноземельного металла. ! 2. Способ по п.1, характеризующийся тем, что микрокапсулы выдерживают в растворе хитозана 25÷30 мин, в растворе хлорида щелочноземельного металла - не менее 25÷30 мин, в растворе альгината натрия - не менее 5÷10 мин, повторно в растворе хлорида щелочноземельного металла - не менее 10÷15 мин. ! 3. Способ по п.1, характеризующийся тем, что в качестве хлорида щелочноземельного металла используют хлорид кальция. ! 4. Способ по п.1, характеризующийся тем, что в качестве хлорида щелочноземельного металла используют хлорид бария. 1. A method of producing shells based on chitosan and salts of alginic acid for microcapsules containing phospholipid micelles, characterized by sequential exposure of the nuclei of microcapsules in 0.5 ÷ 1.0% (wt./about.) A solution of chitosan medium or low viscosity of 1.0 % acetic acid, in 2.5 ÷ 3.0% alkaline earth metal chloride solution, in 0.5 ÷ 1.0% (w / v) sodium alginate solution and, again, in 2.5 ÷ 3.0% alkaline earth metal chloride solution. ! 2. The method according to claim 1, characterized in that the microcapsules are kept in a solution of chitosan for 25-30 minutes, in a solution of alkaline earth metal chloride - at least 25-30 minutes, in a solution of sodium alginate - at least 5-10 minutes, repeatedly in solution alkaline earth metal chloride - at least 10 ÷ 15 minutes ! 3. The method according to claim 1, characterized in that calcium chloride is used as the alkaline earth metal chloride. ! 4. The method according to claim 1, characterized in that barium chloride is used as the alkaline earth metal chloride.
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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RU2009122169/05A RU2411077C1 (en) | 2009-06-09 | 2009-06-09 | Method for producing chitosan and alginic acid coats for microcapsules containing phospholipid micelles |
Applications Claiming Priority (1)
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RU2009122169/05A RU2411077C1 (en) | 2009-06-09 | 2009-06-09 | Method for producing chitosan and alginic acid coats for microcapsules containing phospholipid micelles |
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RU2009122169A true RU2009122169A (en) | 2010-12-20 |
RU2411077C1 RU2411077C1 (en) | 2011-02-10 |
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RU2009122169/05A RU2411077C1 (en) | 2009-06-09 | 2009-06-09 | Method for producing chitosan and alginic acid coats for microcapsules containing phospholipid micelles |
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RU (1) | RU2411077C1 (en) |
Cited By (2)
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RU2662173C1 (en) * | 2017-02-27 | 2018-07-24 | федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") | Method for producing particles of microcapsulated phenhibut in alginate sodium |
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UA103834C2 (en) * | 2012-06-15 | 2013-11-25 | Павел Петрович Пивоваров | Encapsulated protein-containing product and a method for obtaining thereof |
RU2529179C1 (en) * | 2013-04-23 | 2014-09-27 | Общество с ограниченной ответственностью "Уральский центр биофармацевтических технологий" | Liposome suspension stabiliser and method for production thereof |
CN103462895A (en) * | 2013-07-05 | 2013-12-25 | 南昌大学 | Preparation method of layer-by-layer self-assembled double-modified liposome |
RU2669354C1 (en) * | 2017-09-08 | 2018-10-10 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Means for delivery of active agent |
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2009
- 2009-06-09 RU RU2009122169/05A patent/RU2411077C1/en active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2662173C1 (en) * | 2017-02-27 | 2018-07-24 | федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") | Method for producing particles of microcapsulated phenhibut in alginate sodium |
CN113426387A (en) * | 2021-06-11 | 2021-09-24 | 厦门双瑞船舶涂料有限公司 | Natural water-based antifouling paint and preparation method thereof, antifouling agent microcapsule and preparation method thereof |
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RU2411077C1 (en) | 2011-02-10 |
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