RU2004261C1 - Method and apparatus for obtaining gaseous mixture for intermittent normobaric hypoxia - Google Patents

Description

The use of this membrane also provides the necessary apparatus performance and the necessary composition of the gas mixture (oxygen content (10 ± 0.5) - (18 ± 0.5) vol.%

Due to the proposed apparatus design, the resulting hypoxic mixture has such properties (content 02, N2, absence of impurities) that it can be finely and precisely adjusted. Thus, it is possible to individually select the composition and quantity of the gas mixture according to the patient’s diagnosis and the oxygen content in it can vary from 9.5 to 18.5 vol.%. In known apparatuses and devices such an opportunity was not provided.

The drawing shows an apparatus for producing a gas mixture for intermittent normobaric hypoxia.

The apparatus comprises a housing 1, a gas separation unit 2, including compressors 3 and membrane elements 4 made of hollow polymer fibers based on poly-4-methylpentene-1, an oxygen concentration regulator 5, a gas analyzer 6, a pipeline (collector) of the gas mixture 7, s outlet fitting 8, flowmeter 9, humidifier 10, receiver 11, hose 12, patient mask 13, breathing valve 14, programmer 15, means for monitoring the condition of the patient 16 and monitor 17.

Source air through the body fitting

1 they are fed into the gas separation unit 2 for compression in compressor 3 of the UK 40-2M brand and B is supplied with a membrane element 4 of hollow polymer fibers based on poly-4-methylpentene-1. The gas mixture leaving the membrane element is controlled by the oxygen concentration by regulator 5, a part of the gas flow (1/100 part) is sent to the gas analyzer 6, the main part is fed through a pipeline (collector) 7 and its outlet nozzle 8 to the discharge pipes. The resulting gas mixture is fed through a flow meter 9, equipped with a control valve to a humidifier 10, a receiver 11, and through a hose 12 to a patient mask 13 with a breathing valve 14. The procedure of intermittent normobaric hypoxia is controlled by a programmer 15, which is feedback from the patient's heart rate monitor 16 and broadcast to monitor 17.

Source air containing 21 vol.%

02 and 79 vol.% Na enters the gas separation unit, consisting of four compressors of the UK 40-2M brand, where it is compressed to a pressure of 0.35 MPa and directed at a flow rate of 90 l / min through the inlet fitting of the apparatus into the membrane element, where it enters the inside or outside of the hollow polymer fiber membranes based on poly-4-methylpentene-1 having an outer fiber diameter of 65 μm, a fiber wall thickness of 5 equal to 13 μm, and the ratio of these parameters is 5. The membrane element is made in the form of a bundle of hollow polymer fibers isolated by a glass casing tape impregnated with epoxy resin, fixed to the top and bottom by blocks of sealing epoxy material and having fittings for the inlet of the source air and the outlet of the hypoxic gas mixture, as well as the outlet

5 hyperoxic gas mixture. The gas separation apparatus operates at room temperature.

The hypoxic gas mixture leaving the membrane element is controlled

0 by oxygen concentration by the regulator and a mixture containing 10 vol.% 02 and 90 vol.% N2, with a flow rate of 32 l / min, is sent to the pipeline (collector). The collector is equipped with four outlet pipes in number

5 simultaneously served patients. Simultaneously with the regulation of the oxygen concentration in the hypoxic gas mixture, an analysis of the oxygen concentration by a gas analyzer is carried out, which has a feedback link

0 controller connected in parallel to it, gas mixture through humidifier, receiver, etc. enters the mask of the patient.

Intermittent procedure

5 normobaric hypoxia obtained by a hypoxic mixture containing 10 vol.% 02 and 90 vol.% N2 (no impurities) is carried out according to the method approved by the Ministry of Health of the USSR 04.04.85, No. 10-11 / 35

0 as follows. The patient's breathing with a hypoxic gas mixture is carried out in a cyclically fractionated mode: breathing with the mixture for 5 minutes, then breathing with atmospheric air for 3 minutes (one cycle).

5 The number of cycles may vary from 1 to 10 depending on the state of health of the patient. The total breathing time of the hypoxic gas mixture for 1 session (fraction) is 30% - 60 minutes. Number

0 sessions 10-20 depending on the indications. In the entire range of the claimed parameters, a gas mixture is obtained, acting with a similar result.

5 (56) Instruction. A method of increasing nonspecific body resistance using normobaric hypoxic stimulation. M .: 1985, p. 7-9.

USSR copyright certificate Nfe 1526688, cl. A 61 G 10/00, 1989.

Claims (6)

1. A method of producing a gas mixture for intermittent normobaric hypoxia, including depletion of atmospheric air with oxygen by compressing it in a compressor and passing it through a polymer membrane made of hollow fibers, and the subsequent supply of the mixture through the flow meter and humidifier to the patient, characterized in that the source air is compressed to 0.3 to 1.5 MPa, passed through a fiber based on poly-4-methylpentene-1, having a ratio of the outer diameter to wall thickness 2 - 10, and the moistened mixture is fed through the receiver, hose and mask with a breathing valve to the patient. 2. A hypoxicator containing a gas separation unit connected in series, including a compressor and a membrane element made of hollow polymer fibers, a pipeline with an oxygen concentration regulator and a manifold made in the form of a discharge pipe with a flow meter, humidifier, and means for supplying the mixture to the patient, a gas analyzer, and means monitoring the condition of the patient with a monitor, characterized in that it is equipped with a housing and a programmer, the membrane element is made on the basis of poly-4-methylpentene-1, and the collector is Luciano at least one outlet conduit, similar to the core, wherein the gas analyzer is connected in parallel regulator torus collector - to the conduit fitting means is further inputted, the output the programmer - to the monitor, and the input - to the means for monitoring the patient's condition, while the means for supplying the mixture is made in the form of a receiver with a hose and mask with a breathing valve, and a membrane; element, pipeline with regulator and gas | the zoanalyzer and the programmer are housed in a housing. 3. The apparatus according to claim 2, characterized in that the gas separation unit comprises at least one other membrane element similar to the main one. 4. The apparatus according to claims 2 and 3, characterized in that the gas separation unit contains at least one other compress rub. 5. The apparatus according to claims 2 to 4, characterized in that the compressor or compressors are housed in a housing. thirty 6. The apparatus according to claims 2 to 5, characterized in that the collector comprises 2-20 outlet tubes. 1EG