RU2004129745A - 9-AMINOACRIDINE DERIVATIVES AND METHOD FOR PRODUCING THEM - Google Patents

9-AMINOACRIDINE DERIVATIVES AND METHOD FOR PRODUCING THEM Download PDF

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Publication number
RU2004129745A
RU2004129745A RU2004129745/04A RU2004129745A RU2004129745A RU 2004129745 A RU2004129745 A RU 2004129745A RU 2004129745/04 A RU2004129745/04 A RU 2004129745/04A RU 2004129745 A RU2004129745 A RU 2004129745A RU 2004129745 A RU2004129745 A RU 2004129745A
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Russia
Prior art keywords
compound
general formula
following general
pharmaceutically acceptable
acceptable salt
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RU2004129745/04A
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Russian (ru)
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RU2269524C2 (en
Inventor
Еун-Хван ЧО (KR)
Еун-Хван ЧО
Сун-Ган ЧУНГ (KR)
Сун-Ган ЧУНГ
Сун-Хван ЛИ (KR)
Сун-Хван ЛИ
Хо-Сеок КВОН (KR)
Хо-Сеок КВОН
Донг-Воок КАНГ (KR)
Донг-Воок КАНГ
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Самдзин Фармасьютикал Ко.,Лтд. (Kr)
Самдзин Фармасьютикал Ко.,Лтд.
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Priority to RU2004129745/04A priority Critical patent/RU2269524C2/en
Publication of RU2004129745A publication Critical patent/RU2004129745A/en
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Claims (3)

1. Соединение общей формулы (I)1. The compound of General formula (I)
Figure 00000001
Figure 00000001
 где Y отсутствует или представляет собойwhere Y is absent or represents
Figure 00000002
Figure 00000002
 где Х означает кислород или серу, R1, R2, R3, R4 и R5 независимо означают водород, галоген, нитро, амино, гидрокси, С1-С4 низший алкиламино, С1-С4алкил или С1-С4 низший алкокси, R’ и R’’ независимо представляют собой С1-С4алкил или С1-С4 низший алкокси, и Z означает С1-С4 низший алкил, С1-С4 низший алкокси или С1-С4 низший алкиламино, и его фармацевтически приемлемая соль.where X is oxygen or sulfur, R 1 , R 2 , R 3 , R 4 and R 5 independently mean hydrogen, halogen, nitro, amino, hydroxy, C 1 -C 4 lower alkylamino, C 1 -C 4 alkyl or C 1 —C 4 lower alkoxy, R ′ and R ″ independently are C 1 -C 4 alkyl or C 1 -C 4 lower alkoxy, and Z is C 1 -C 4 lower alkyl, C 1 -C 4 lower alkoxy or C 1 -C 4 lower alkylamino, and a pharmaceutically acceptable salt thereof. 2. Способ получения соединения следующей общей формулы (I) или его фармацевтически приемлемой соли, включающий взаимодействие соединения следующей общей формулы (а) с соединением следующей общей формулы (b) с получением соединения следующей общей формулы (I) и, если необходимо, преобразование соединения общей формулы (I) в его фармацевтически приемлемую соль.2. A method of obtaining a compound of the following general formula (I) or a pharmaceutically acceptable salt thereof, comprising reacting a compound of the following general formula (a) with a compound of the following general formula (b) to obtain a compound of the following general formula (I) and, if necessary, converting the compound general formula (I) in a pharmaceutically acceptable salt thereof. 3. Способ получения соединения следующей общей формулы (I) или его фармацевтически приемлемой соли, включающий взаимодействие соединения следующей общей формулы (с) с соединением следующей общей формулы (d) с получением соединения следующей общей формулы (I) и, если необходимо, преобразование соединения общей формулы (I) в его фармацевтически приемлемую соль.3. A method for producing a compound of the following general formula (I) or a pharmaceutically acceptable salt thereof, comprising reacting a compound of the following general formula (c) with a compound of the following general formula (d) to produce a compound of the following general formula (I) and, if necessary, converting the compound general formula (I) in a pharmaceutically acceptable salt thereof.
Figure 00000003
Figure 00000003
Figure 00000004
Figure 00000004
 где R1, R2, R3, R4, R5, R’, R’’, X, Y и Z такие, как указано выше, и Y означает -OH или группу
Figure 00000005
where R 1 , R 2 , R 3 , R 4 , R 5 , R ′, R ″, X, Y and Z are as defined above, and Y is —OH or a group
Figure 00000005
RU2004129745/04A 2002-03-07 2002-03-07 Derivatives of 9-aminoacridine and method for their preparing RU2269524C2 (en)

Priority Applications (1)

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RU2004129745/04A RU2269524C2 (en) 2002-03-07 2002-03-07 Derivatives of 9-aminoacridine and method for their preparing

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RU2269524C2 RU2269524C2 (en) 2006-02-10

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Effective date: 20110308