RU2003106940A - DIAGNOSTIC METHOD FOR REFLUX NEPHROPATHY - Google Patents

DIAGNOSTIC METHOD FOR REFLUX NEPHROPATHY

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Publication number
RU2003106940A
RU2003106940A RU2003106940/15A RU2003106940A RU2003106940A RU 2003106940 A RU2003106940 A RU 2003106940A RU 2003106940/15 A RU2003106940/15 A RU 2003106940/15A RU 2003106940 A RU2003106940 A RU 2003106940A RU 2003106940 A RU2003106940 A RU 2003106940A
Authority
RU
Russia
Prior art keywords
reflux nephropathy
content
diagnostic method
reflux
tnf
Prior art date
Application number
RU2003106940/15A
Other languages
Russian (ru)
Other versions
RU2239838C1 (en
Inventor
Иван Евгеньевич Смирнов
Светлана Стояновна Паунова
Алла Георгиевна Кучеренко
Елена Борисовна Ольхова
Original Assignee
Научный Центр Здоровья детей РАМН
Filing date
Publication date
Application filed by Научный Центр Здоровья детей РАМН filed Critical Научный Центр Здоровья детей РАМН
Priority to RU2003106940/15A priority Critical patent/RU2239838C1/en
Priority claimed from RU2003106940/15A external-priority patent/RU2239838C1/en
Publication of RU2003106940A publication Critical patent/RU2003106940A/en
Application granted granted Critical
Publication of RU2239838C1 publication Critical patent/RU2239838C1/en

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Claims (1)

Способ диагностики рефлюкс-нефропатии, включающий иммуноферментный анализ мочи на содержание цитокинов, отличающийся тем, что определяют содержание ИЛ 8, 10 и ФНО-α в суточной моче дважды: при первичном обследовании и через 6 месяцев, и при снижении содержания интерлейкина-10 более чем в 1,3 раза, при повышении содержания ФНО-α более чем в 1,4 раза по сравнению с первоначальным значением, на фоне постоянной величины ИЛ-8, свидетельствует о развитии рефлюкс-нефропатии у больных с пузырно-мочеточниковым рефлюксом.A method for the diagnosis of reflux nephropathy, including enzyme-linked immunosorbent assay for urine cytokines, characterized in that they determine the content of IL 8, 10 and TNF-α in daily urine twice: during the initial examination and after 6 months, and with a decrease in the content of interleukin-10 more than 1.3 times, with an increase in the content of TNF-α by more than 1.4 times compared to the initial value, against the background of a constant IL-8, indicates the development of reflux nephropathy in patients with vesicoureteral reflux.
RU2003106940/15A 2003-03-14 2003-03-14 Method for diagnosing reflux nephropathy RU2239838C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2003106940/15A RU2239838C1 (en) 2003-03-14 2003-03-14 Method for diagnosing reflux nephropathy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2003106940/15A RU2239838C1 (en) 2003-03-14 2003-03-14 Method for diagnosing reflux nephropathy

Publications (2)

Publication Number Publication Date
RU2003106940A true RU2003106940A (en) 2004-09-27
RU2239838C1 RU2239838C1 (en) 2004-11-10

Family

ID=34310524

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2003106940/15A RU2239838C1 (en) 2003-03-14 2003-03-14 Method for diagnosing reflux nephropathy

Country Status (1)

Country Link
RU (1) RU2239838C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2478210C1 (en) * 2011-10-27 2013-03-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Оренбургская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО ОрГМА Минздравсоцразвития России) Diagnostic technique for reflux nephropathy a in children with vesicoureteral reflux

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