RU2002131380A - PHARMACEUTICAL COMPOSITIONS - Google Patents
PHARMACEUTICAL COMPOSITIONSInfo
- Publication number
- RU2002131380A RU2002131380A RU2002131380/15A RU2002131380A RU2002131380A RU 2002131380 A RU2002131380 A RU 2002131380A RU 2002131380/15 A RU2002131380/15 A RU 2002131380/15A RU 2002131380 A RU2002131380 A RU 2002131380A RU 2002131380 A RU2002131380 A RU 2002131380A
- Authority
- RU
- Russia
- Prior art keywords
- composition according
- sweeteners
- preceding paragraphs
- mass ratio
- composition
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 3
- 239000000203 mixture Substances 0.000 claims 13
- 235000003599 food sweetener Nutrition 0.000 claims 8
- 239000003765 sweetening agent Substances 0.000 claims 8
- 239000003607 modifier Substances 0.000 claims 5
- IAOZJIPTCAWIRG-QWRGUYRKSA-N Aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims 3
- 229960003438 Aspartame Drugs 0.000 claims 3
- 108010011485 Aspartame Proteins 0.000 claims 3
- 239000000605 aspartame Substances 0.000 claims 3
- 235000010357 aspartame Nutrition 0.000 claims 3
- 150000002632 lipids Chemical class 0.000 claims 3
- KEJCWVGMRLCZQQ-DJMWJSSGSA-N 1-acetyloxyethyl (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2E)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(=O)OC(C)OC(C)=O)=O)C(=O)/C(=N/OC)C1=CC=CO1 KEJCWVGMRLCZQQ-DJMWJSSGSA-N 0.000 claims 2
- WINXNKPZLFISPD-UHFFFAOYSA-M Saccharin sodium Chemical compound [Na+].C1=CC=C2C(=O)[N-]S(=O)(=O)C2=C1 WINXNKPZLFISPD-UHFFFAOYSA-M 0.000 claims 2
- 229960002620 cefuroxime axetil Drugs 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 239000000230 xanthan gum Substances 0.000 claims 2
- 235000010493 xanthan gum Nutrition 0.000 claims 2
- 229920001285 xanthan gum Polymers 0.000 claims 2
- 229940082509 xanthan gum Drugs 0.000 claims 2
- CWSZBVAUYPTXTG-UHFFFAOYSA-N 5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol Chemical compound O1C(CO)C(OC)C(O)C(O)C1OCC1C(OC2C(C(O)C(OC)C(CO)O2)OCCO)C(O)C(O)C(OC2C(OC(C)C(O)C2O)CO)O1 CWSZBVAUYPTXTG-UHFFFAOYSA-N 0.000 claims 1
- 229940113118 Carrageenan Drugs 0.000 claims 1
- 210000004051 Gastric Juice Anatomy 0.000 claims 1
- 240000005389 Glycyrrhiza glabra Species 0.000 claims 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims 1
- 229920002907 Guar gum Polymers 0.000 claims 1
- 235000017443 Hedysarum boreale Nutrition 0.000 claims 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 claims 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- XAPRFLSJBSXESP-UHFFFAOYSA-N Oxycinchophen Chemical compound N=1C2=CC=CC=C2C(C(=O)O)=C(O)C=1C1=CC=CC=C1 XAPRFLSJBSXESP-UHFFFAOYSA-N 0.000 claims 1
- 229960001462 Sodium Cyclamate Drugs 0.000 claims 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 150000003863 ammonium salts Chemical class 0.000 claims 1
- 239000007900 aqueous suspension Substances 0.000 claims 1
- 235000021311 artificial sweeteners Nutrition 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 235000019658 bitter taste Nutrition 0.000 claims 1
- BSGNIBMMMFYKOB-UHFFFAOYSA-L calcium;6-methyl-2,2-dioxooxathiazin-4-olate Chemical compound [Ca+2].CC1=CC([O-])=NS(=O)(=O)O1.CC1=CC([O-])=NS(=O)(=O)O1 BSGNIBMMMFYKOB-UHFFFAOYSA-L 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 239000000679 carrageenan Substances 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 239000000665 guar gum Substances 0.000 claims 1
- 235000010417 guar gum Nutrition 0.000 claims 1
- 229960002154 guar gum Drugs 0.000 claims 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 235000014063 licorice root Nutrition 0.000 claims 1
- 235000021096 natural sweeteners Nutrition 0.000 claims 1
- ITVGXXMINPYUHD-CUVHLRMHSA-N neohesperidin dihydrochalcone Chemical compound C1=C(O)C(OC)=CC=C1CCC(=O)C(C(=C1)O)=C(O)C=C1O[C@H]1[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 ITVGXXMINPYUHD-CUVHLRMHSA-N 0.000 claims 1
- 239000000879 neohesperidine DC Substances 0.000 claims 1
- 239000000546 pharmaceutic aid Substances 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims 1
- 239000000892 thaumatin Substances 0.000 claims 1
- 235000010436 thaumatin Nutrition 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Claims (12)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01500277.7 | 2001-11-23 | ||
EP01500277 | 2001-11-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2002131380A true RU2002131380A (en) | 2004-06-27 |
RU2241460C2 RU2241460C2 (en) | 2004-12-10 |
Family
ID=8183502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2002131380/15A RU2241460C2 (en) | 2001-11-23 | 2002-11-21 | Cefuroxime axetyl-containing pharmaceutical composition with masked bitter taste |
Country Status (34)
Country | Link |
---|---|
US (1) | US20030161888A1 (en) |
EP (1) | EP1446126B1 (en) |
JP (1) | JP3497503B2 (en) |
KR (1) | KR100979328B1 (en) |
CN (1) | CN1297274C (en) |
AT (1) | ATE473006T1 (en) |
AU (2) | AU2002338950A1 (en) |
BE (2) | BE1014078A6 (en) |
BR (1) | BR0204767A (en) |
CA (1) | CA2408198C (en) |
CH (1) | CH693982A5 (en) |
CO (1) | CO5580783A2 (en) |
CY (1) | CY1110778T1 (en) |
CZ (1) | CZ12993U1 (en) |
DE (3) | DE20218068U1 (en) |
DK (1) | DK1446126T3 (en) |
ES (2) | ES2201932B2 (en) |
FR (1) | FR2832635B1 (en) |
GB (1) | GB2383536B (en) |
GR (1) | GR1004522B (en) |
HR (2) | HRP20020923A2 (en) |
HU (1) | HUP0204026A3 (en) |
IL (2) | IL161972A0 (en) |
IT (1) | ITMI20022470A1 (en) |
MX (1) | MXPA02011561A (en) |
NO (1) | NO335273B1 (en) |
NZ (1) | NZ533092A (en) |
PL (1) | PL205325B1 (en) |
PT (1) | PT1446126E (en) |
RU (1) | RU2241460C2 (en) |
SI (1) | SI1446126T1 (en) |
TR (1) | TR200202559A2 (en) |
WO (1) | WO2003043638A1 (en) |
ZA (1) | ZA200209473B (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
ES2517244T3 (en) | 2004-05-11 | 2014-11-03 | Egalet Ltd. | Inflatable pharmaceutical form comprising gellan gum |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
EP1802285B1 (en) | 2004-10-21 | 2013-02-27 | Aptalis Pharmatech, Inc. | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
JP2012107060A (en) * | 2004-12-15 | 2012-06-07 | Aska Pharmaceutical Co Ltd | Oral formulation in which bitter taste of isosorbide was alleviated, method for producing the same |
JP4972311B2 (en) * | 2004-12-15 | 2012-07-11 | あすか製薬株式会社 | Oral preparation with reduced bitter taste of isosorbide and method for producing the same |
DE102005019458A1 (en) * | 2005-04-25 | 2006-10-26 | Grünenthal GmbH | Composition, useful in the preparation of pellets and the multi-particular-presentation form, comprises cefuroximaxetil and carrageenan of the group of lambda carrageenan, tau carrageenan and kappa carrageenan |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
CN100402035C (en) * | 2005-07-07 | 2008-07-16 | 石药集团中奇制药技术(石家庄)有限公司 | A pharmaceutical composition of microencapsulated cefuroxime axetil |
US8637076B2 (en) * | 2006-06-01 | 2014-01-28 | Cima Labs Inc. | Prednisolone salt formulations |
US20070281014A1 (en) * | 2006-06-01 | 2007-12-06 | Cima Labs, Inc. | Prednisolone salt formulations |
CN101756906B (en) * | 2009-11-02 | 2011-11-16 | 严洁 | Pharmaceutical composition of cefcapene pivoxil hydrochloride granules and preparation method thereof |
AU2010325746B2 (en) | 2009-12-02 | 2016-02-25 | Adare Pharmaceuticals S.R.L. | Fexofenadine microcapsules and compositions containing them |
TW201127375A (en) * | 2010-01-08 | 2011-08-16 | Eurand Inc | Taste masked topiramate composition and an orally disintegrating tablet comprising the same |
WO2011139254A2 (en) | 2010-05-04 | 2011-11-10 | Mahmut Bilgic | Pharmaceutical formulations compising cefuroxime axetil |
JP5853461B2 (en) * | 2010-07-30 | 2016-02-09 | 大正製薬株式会社 | Oral solution |
EP2741750A1 (en) | 2011-08-12 | 2014-06-18 | Dhanuka Laboratories Ltd. | Pharmaceutical composition comprising cefuroxime |
CN102440960A (en) * | 2011-09-01 | 2012-05-09 | 山东鲁抗医药股份有限公司 | Pharmaceutical composition of cefuroxime axetil for suspension and preparation method thereof |
CA2852912A1 (en) * | 2011-10-31 | 2013-05-10 | Glaxosmithkline Intellectual Property Limited | Pazopanib formulation |
CN108338936A (en) * | 2017-01-23 | 2018-07-31 | 刘全忠 | The preparation and use of sensitive skin protective lotion |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1323161A (en) * | 1970-02-16 | 1973-07-11 | Wyeth John & Brother Ltd | Penicillin composition |
CA1094545A (en) * | 1976-02-16 | 1981-01-27 | Michael Gregson | Cephalosporin antibiotics |
GB1571683A (en) * | 1976-02-16 | 1980-07-16 | Glaxo Operations Ltd | Ester derivatives of cefuroxime |
YU44680B (en) * | 1982-07-30 | 1990-12-31 | Glaxo Lab Ltd | Process for obtaining very pure amorphous form of cephuroxim axetile |
GB8320520D0 (en) * | 1983-07-29 | 1983-09-01 | Glaxo Group Ltd | Chemical process |
GB8524001D0 (en) * | 1985-09-30 | 1985-11-06 | Glaxo Group Ltd | Pharmaceutical composition |
NL193682C (en) * | 1987-05-14 | 2000-07-04 | Glaxo Group Ltd | Coated Cefuroxime Maxetil Composition. |
US4992276A (en) * | 1988-12-14 | 1991-02-12 | Warner-Lambert Company | Antiseptic compositions containing hexahydro-5-pyrimidinamine compounds and thymol and methods for preparing same |
EP0670716B1 (en) * | 1992-11-30 | 2003-03-26 | Kv Pharmaceutical Company | Tastemasked pharmaceutical materials |
IT1277426B1 (en) * | 1995-08-03 | 1997-11-10 | Acs Dobfar Spa | BIOAVAILABLE CRYSTALLINE FORM OF CEFUROXIMA AXETIL |
NZ299077A (en) * | 1996-07-26 | 1998-06-26 | Apotex Inc | Preparation of amorphous cefuroxime axetil (a cephalosporin derivative) by dissolving crystalline cefuroxim axetil in a highly polar solvent, typically dmso and/or dmf |
DE69730982T2 (en) * | 1996-10-28 | 2005-09-01 | General Mills, Inc., Minneapolis | Encapsulation and encapsulation of particles for controlled release |
CA2209868C (en) * | 1997-08-15 | 2001-08-14 | Bernard Charles Sherman | Pharmaceutical compositions comprising cefuroxime axetil |
GB9726781D0 (en) * | 1997-12-19 | 1998-02-18 | Glaxo Group Ltd | Pharmaceutical composition |
AT413647B (en) * | 1998-11-26 | 2006-04-15 | Sandoz Ag | USE OF A COPOLYMERISATE OF 1-VINYL-2-PYRROLIDONE AND VINYL ACETATE FOR THE PREPARATION OF CEFUROXIMAXETIL-SUBJECTED TABLETS |
-
2002
- 2002-11-20 HR HR20020923A patent/HRP20020923A2/en not_active Application Discontinuation
- 2002-11-20 ES ES200202670A patent/ES2201932B2/en not_active Expired - Fee Related
- 2002-11-20 CZ CZ200213690U patent/CZ12993U1/en not_active IP Right Cessation
- 2002-11-20 HR HR20020924A patent/HRP20020924A2/en not_active Application Discontinuation
- 2002-11-21 ES ES02777359T patent/ES2347536T3/en not_active Expired - Lifetime
- 2002-11-21 ZA ZA200209473A patent/ZA200209473B/en unknown
- 2002-11-21 GB GB0227215A patent/GB2383536B/en not_active Expired - Fee Related
- 2002-11-21 IT IT002470A patent/ITMI20022470A1/en unknown
- 2002-11-21 CN CNB021522375A patent/CN1297274C/en not_active Expired - Lifetime
- 2002-11-21 GR GR20020100506A patent/GR1004522B/en unknown
- 2002-11-21 WO PCT/EP2002/013150 patent/WO2003043638A1/en not_active Application Discontinuation
- 2002-11-21 AT AT02777359T patent/ATE473006T1/en active
- 2002-11-21 BE BE2002/0667A patent/BE1014078A6/en not_active IP Right Cessation
- 2002-11-21 MX MXPA02011561A patent/MXPA02011561A/en active IP Right Grant
- 2002-11-21 EP EP02777359A patent/EP1446126B1/en not_active Expired - Lifetime
- 2002-11-21 JP JP2002337570A patent/JP3497503B2/en not_active Expired - Fee Related
- 2002-11-21 RU RU2002131380/15A patent/RU2241460C2/en active
- 2002-11-21 HU HU0204026A patent/HUP0204026A3/en unknown
- 2002-11-21 TR TR2002/02559A patent/TR200202559A2/en unknown
- 2002-11-21 PT PT02777359T patent/PT1446126E/en unknown
- 2002-11-21 FR FR0214587A patent/FR2832635B1/en not_active Expired - Fee Related
- 2002-11-21 BE BE2002/0668A patent/BE1015217A5/fr not_active IP Right Cessation
- 2002-11-21 AU AU2002338950A patent/AU2002338950A1/en not_active Abandoned
- 2002-11-21 DE DE20218068U patent/DE20218068U1/en not_active Expired - Lifetime
- 2002-11-21 IL IL16197202A patent/IL161972A0/en unknown
- 2002-11-21 AU AU2002302147A patent/AU2002302147B2/en not_active Ceased
- 2002-11-21 BR BR0204767-5A patent/BR0204767A/en not_active IP Right Cessation
- 2002-11-21 US US10/301,452 patent/US20030161888A1/en not_active Abandoned
- 2002-11-21 CA CA002408198A patent/CA2408198C/en not_active Expired - Lifetime
- 2002-11-21 PL PL357259A patent/PL205325B1/en unknown
- 2002-11-21 NZ NZ533092A patent/NZ533092A/en not_active IP Right Cessation
- 2002-11-21 DE DE10254412A patent/DE10254412A1/en not_active Withdrawn
- 2002-11-21 DE DE60236952T patent/DE60236952D1/en not_active Expired - Lifetime
- 2002-11-21 CH CH01954/02A patent/CH693982A5/en not_active IP Right Cessation
- 2002-11-21 DK DK02777359.7T patent/DK1446126T3/en active
- 2002-11-21 SI SI200230920T patent/SI1446126T1/en unknown
- 2002-11-21 KR KR1020047007847A patent/KR100979328B1/en active IP Right Grant
-
2004
- 2004-05-13 IL IL161972A patent/IL161972A/en active IP Right Grant
- 2004-05-18 CO CO04045861A patent/CO5580783A2/en not_active Application Discontinuation
- 2004-06-22 NO NO20042620A patent/NO335273B1/en not_active IP Right Cessation
-
2010
- 2010-09-13 CY CY20101100828T patent/CY1110778T1/en unknown
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2002131380A (en) | PHARMACEUTICAL COMPOSITIONS | |
DE20218068U1 (en) | drug | |
US4760094A (en) | Spray dried acetaminophen | |
ES2215223T3 (en) | LIQUID SUSPENSIONS OF MASKED FLAVOR. | |
KR920702215A (en) | Pharmaceutical compositions that rapidly form suspensions in water | |
PT1276469E (en) | Taste masking coating composition | |
BRPI0820308B1 (en) | PHARMACEUTICAL COMPOSITION UNDERSTANDING HIGH LOAD IRON OXYHYDROXIDE, ITS USES AND PREPARATION PROCESSES, AND TABLET | |
JPH11178539A (en) | Granular sweetener | |
WO2000002536A1 (en) | Croscarmellose taste masking | |
GB2192790A (en) | Acetylcysteine compositions | |
US4767789A (en) | Spray dried acetaminophen | |
ES2288152T3 (en) | SOLID PREPARATIONS CONTAINING CHITOSANE POWDER AND ASSOCIATED PRODUCTION PROCEDURE. | |
US6726928B2 (en) | Process for preparing solid dosage forms for unpalatable pharmaceuticals | |
EP0331385B1 (en) | Aqueous suspension of sucralfate | |
PT94987A (en) | PROCESS FOR THE PREPARATION OF AN INSOLUBLE DRUG IN WATER, ANTI-INFLAMMATORY, NON-STEROID, MICROENCAPSULATED | |
US20040091536A1 (en) | Telithromycin suspension with masked taste | |
JP2726498B2 (en) | Oral solid preparation | |
ES2307099T3 (en) | CO-PRECIPITATE QUITOSAN-SILICON DIOXIDE AND USE AS EXCIPIENT IN SOLID DOSAGE FORMS. | |
JPH0322874B2 (en) | ||
JPWO2021119456A5 (en) | ||
TH23580A (en) | A new pharmaceutical formulation containing trymbutene and a process for preparing it. |